Proto-Oncogene Proteins c-rel
"Proto-Oncogene Proteins c-rel" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Cellular DNA-binding proteins encoded by the rel gene (GENES, REL). They are expressed predominately in hematopoietic cells and may play a role in lymphocyte differentiation. Rel frequently combines with other related proteins (NF-KAPPA B, I-kappa B, relA) to form heterodimers that regulate transcription. Rearrangement or overexpression of c-rel can cause tumorigenesis.
Descriptor ID |
D020569
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MeSH Number(s) |
D12.776.260.682 D12.776.624.664.700.192 D12.776.660.767 D12.776.930.730
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Concept/Terms |
Proto-Oncogene Proteins c-rel- Proto-Oncogene Proteins c-rel
- Proto Oncogene Proteins c rel
- c-rel, Proto-Oncogene Proteins
- p68 c-rel
- c-rel, p68
- p68 c rel
- Proto-Oncogene Protein c-rel
- Proto Oncogene Protein c rel
- c-rel, Proto-Oncogene Protein
- Proto-Oncogene Proteins rel
- Proto Oncogene Proteins rel
- c-rel Protein
- Protein, c-rel
- c rel Protein
- p68(c-rel)
- rel Proto-Oncogene Product p68
- rel Proto Oncogene Product p68
- Proto-Oncogene Products c-rel
- Proto Oncogene Products c rel
- c-rel, Proto-Oncogene Products
- c-rel Proteins
- Proteins, c-rel
- c rel Proteins
- rel Proto-Oncogene Proteins
- Proto-Oncogene Proteins, rel
- rel Proto Oncogene Proteins
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Below are MeSH descriptors whose meaning is more general than "Proto-Oncogene Proteins c-rel".
Below are MeSH descriptors whose meaning is more specific than "Proto-Oncogene Proteins c-rel".
This graph shows the total number of publications written about "Proto-Oncogene Proteins c-rel" by people in this website by year, and whether "Proto-Oncogene Proteins c-rel" was a major or minor topic of these publications.
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Year | Major Topic | Minor Topic | Total |
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1996 | 0 | 1 | 1 |
1999 | 0 | 1 | 1 |
2006 | 0 | 1 | 1 |
2008 | 0 | 1 | 1 |
2011 | 1 | 0 | 1 |
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Below are the most recent publications written about "Proto-Oncogene Proteins c-rel" by people in Profiles.
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Valent?n-Acevedo A, Sinquett FL, Covey LR. c-Rel deficiency increases caspase-4 expression and leads to ER stress and necrosis in EBV-transformed cells. PLoS One. 2011; 6(10):e25467.
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Rafati DS, Geissler K, Johnson K, Unabia G, Hulsebosch C, Nesic-Taylor O, Perez-Polo JR. Nuclear factor-kappaB decoy amelioration of spinal cord injury-induced inflammation and behavior outcomes. J Neurosci Res. 2008 Feb 15; 86(3):566-80.
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Mukhopadhyay NK, Ferdinand AS, Mukhopadhyay L, Cinar B, Lutchman M, Richie JP, Freeman MR, Liu BC. Unraveling androgen receptor interactomes by an array-based method: discovery of proto-oncoprotein c-Rel as a negative regulator of androgen receptor. Exp Cell Res. 2006 Nov 15; 312(19):3782-95.
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Huxford T, Malek S, Ghosh G. Structure and mechanism in NF-kappa B/I kappa B signaling. Cold Spring Harb Symp Quant Biol. 1999; 64:533-40.
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Govind S. Rel signalling pathway and the melanotic tumour phenotype of Drosophila. Biochem Soc Trans. 1996 Feb; 24(1):39-44.