Chemokine CXCL1

"Chemokine CXCL1" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure, which enables searching at various levels of specificity.

MeSH information

Definition | Details | More General Concepts | Related Concepts | More Specific Concepts

A CXC chemokine with specificity for CXCR2 RECEPTORS. It has growth factor activities and is implicated as a oncogenic factor in several tumor types.

Descriptor ID	D054360
MeSH Number(s)	D12.644.276.374.200.120.050 D12.776.467.374.200.120.050 D12.776.624.664.700.049 D23.125.300.120.050 D23.469.200.120.050 D23.529.374.200.120.050
Concept/Terms	Chemokine CXCL1 Chemokine CXCL1 CXCL1, Chemokine CXCL1 Chemokine Chemokine, CXCL1 Gro-alpha Protein Gro alpha Protein GROalpha Protein Melanoma Growth Stimulatory Activity, alpha Protein MGSA-alpha Chemokine Chemokine, MGSA-alpha MGSA alpha Chemokine Neutrophil-Activating Protein 3 Neutrophil Activating Protein 3 Chemokine (C-X-C Motif) Ligand 1 Growth-Related Oncogene alpha Protein Growth Related Oncogene alpha Protein

Below are MeSH descriptors whose meaning is more general than "Chemokine CXCL1".

Chemicals and Drugs [D]
Amino Acids, Peptides, and Proteins [D12]
Peptides [D12.644]
Intercellular Signaling Peptides and Proteins [D12.644.276]
Cytokines [D12.644.276.374]
Chemokines [D12.644.276.374.200]
Chemokines, CXC [D12.644.276.374.200.120]
Chemokine CXCL1 [D12.644.276.374.200.120.050]
Proteins [D12.776]
Intercellular Signaling Peptides and Proteins [D12.776.467]
Cytokines [D12.776.467.374]
Chemokines [D12.776.467.374.200]
Chemokines, CXC [D12.776.467.374.200.120]
Chemokine CXCL1 [D12.776.467.374.200.120.050]
Neoplasm Proteins [D12.776.624]
Oncogene Proteins [D12.776.624.664]
Proto-Oncogene Proteins [D12.776.624.664.700]
Chemokine CXCL1 [D12.776.624.664.700.049]
Biological Factors [D23]
Chemotactic Factors [D23.125]
Chemokines [D23.125.300]
Chemokines, CXC [D23.125.300.120]
Chemokine CXCL1 [D23.125.300.120.050]
Inflammation Mediators [D23.469]
Chemokines [D23.469.200]
Chemokines, CXC [D23.469.200.120]
Chemokine CXCL1 [D23.469.200.120.050]
Intercellular Signaling Peptides and Proteins [D23.529]
Cytokines [D23.529.374]
Chemokines [D23.529.374.200]
Chemokines, CXC [D23.529.374.200.120]
Chemokine CXCL1 [D23.529.374.200.120.050]

Below are MeSH descriptors whose meaning is related to "Chemokine CXCL1".

Below are MeSH descriptors whose meaning is more specific than "Chemokine CXCL1".

publications

Timeline | Most Recent

This graph shows the total number of publications written about "Chemokine CXCL1" by people in this website by year, and whether "Chemokine CXCL1" was a major or minor topic of these publications.

Bar chart showing 11 publications over 10 distinct years, with a maximum of 2 publications in 2016

To see the data from this visualization as text, click here.

Year	Major Topic	Minor Topic	Total
2006	0	1	1
2007	1	0	1
2008	0	1	1
2011	1	0	1
2012	1	0	1
2013	0	1	1
2015	0	1	1
2016	0	2	2
2017	1	0	1
2021	1	0	1

Below are the most recent publications written about "Chemokine CXCL1" by people in Profiles.

Mendonca P, Alghamdi S, Messeha S, Soliman KFA. Pentagalloyl glucose inhibits TNF-a-activated CXCL1/GRO-a expression and induces apoptosis-related genes in triple-negative breast cancer cells. Sci Rep. 2021 03 11; 11(1):5649.

View in: PubMed
Bhat K, Sarkissyan M, Wu Y, Vadgama JV. GROa overexpression drives cell migration and invasion in triple negative breast cancer cells. Oncol Rep. 2017 Jul; 38(1):21-30.

View in: PubMed
Ho MH, Guo ZM, Chunga J, Goodwin JS, Xie H. Characterization of Innate Immune Responses of Human Endothelial Cells Induced by Porphyromonas gingivalis and Their Derived Outer Membrane Vesicles. Front Cell Infect Microbiol. 2016; 6:139.

View in: PubMed
Ignacio RM, Kabir SM, Lee ES, Adunyah SE, Son DS. NF-?B-Mediated CCL20 Reigns Dominantly in CXCR2-Driven Ovarian Cancer Progression. PLoS One. 2016; 11(10):e0164189.

View in: PubMed
Matsuzaki H, Mikami Y, Makita K, Takeshima H, Horie M, Noguchi S, Jo T, Narumoto O, Kohyama T, Takizawa H, Nagase T, Yamauchi Y. Interleukin-17A and Toll-Like Receptor 3 Ligand Poly(I:C) Synergistically Induced Neutrophil Chemoattractant Production by Bronchial Epithelial Cells. PLoS One. 2015; 10(10):e0141746.

View in: PubMed
Dong YL, Kabir SM, Lee ES, Son DS. CXCR2-driven ovarian cancer progression involves upregulation of proinflammatory chemokines by potentiating NF-?B activation via EGFR-transactivated Akt signaling. PLoS One. 2013; 8(12):e83789.

View in: PubMed
Metkar S, Kim KS, Silver J, Goyert SM. Differential expression of CD14-dependent and independent pathways for chemokine induction regulates neutrophil trafficking in infection. J Leukoc Biol. 2012 Aug; 92(2):389-96.

View in: PubMed
Wang Q, Li D, Zhang W, Tang B, Li QQ, Li L. Evaluation of proteomics-identified CCL18 and CXCL1 as circulating tumor markers for differential diagnosis between ovarian carcinomas and benign pelvic masses. Int J Biol Markers. 2011 Oct-Dec; 26(4):262-73.

View in: PubMed
Cardona AE, Sasse ME, Liu L, Cardona SM, Mizutani M, Savarin C, Hu T, Ransohoff RM. Scavenging roles of chemokine receptors: chemokine receptor deficiency is associated with increased levels of ligand in circulation and tissues. Blood. 2008 Jul 15; 112(2):256-63.

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Son DS, Parl AK, Rice VM, Khabele D. Keratinocyte chemoattractant (KC)/human growth-regulated oncogene (GRO) chemokines and pro-inflammatory chemokine networks in mouse and human ovarian epithelial cancer cells. Cancer Biol Ther. 2007 Aug; 6(8):1302-12.

View in: PubMed

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