Chemokines

"Chemokines" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure, which enables searching at various levels of specificity.

MeSH information

Definition | Details | More General Concepts | Related Concepts | More Specific Concepts

Class of pro-inflammatory cytokines that have the ability to attract and activate leukocytes. They can be divided into at least three structural branches: C; (CHEMOKINES, C); CC; (CHEMOKINES, CC); and CXC; (CHEMOKINES, CXC); according to variations in a shared cysteine motif.

Descriptor ID	D018925
MeSH Number(s)	D12.644.276.374.200 D12.776.467.374.200 D23.125.300 D23.469.200 D23.529.374.200
Concept/Terms	Chemokines Chemokines Cytokines, Chemotactic Intercrines Chemotactic Cytokines

Below are MeSH descriptors whose meaning is more general than "Chemokines".

Chemicals and Drugs [D]
Amino Acids, Peptides, and Proteins [D12]
Peptides [D12.644]
Intercellular Signaling Peptides and Proteins [D12.644.276]
Cytokines [D12.644.276.374]
Chemokines [D12.644.276.374.200]
Proteins [D12.776]
Intercellular Signaling Peptides and Proteins [D12.776.467]
Cytokines [D12.776.467.374]
Chemokines [D12.776.467.374.200]
Biological Factors [D23]
Chemotactic Factors [D23.125]
Chemokines [D23.125.300]
Inflammation Mediators [D23.469]
Chemokines [D23.469.200]
Intercellular Signaling Peptides and Proteins [D23.529]
Cytokines [D23.529.374]
Chemokines [D23.529.374.200]

Below are MeSH descriptors whose meaning is more specific than "Chemokines".

publications

Timeline | Most Recent

This graph shows the total number of publications written about "Chemokines" by people in this website by year, and whether "Chemokines" was a major or minor topic of these publications.

Bar chart showing 66 publications over 25 distinct years, with a maximum of 6 publications in 2012

To see the data from this visualization as text, click here.

Year	Major Topic	Minor Topic	Total
1997	1	0	1
2000	1	0	1
2001	0	2	2
2002	2	0	2
2003	1	2	3
2004	2	0	2
2005	2	2	4
2006	2	1	3
2007	2	0	2
2008	2	1	3
2009	0	1	1
2010	0	2	2
2011	1	2	3
2012	1	5	6
2013	4	1	5
2014	0	3	3
2015	2	3	5
2016	3	1	4
2017	2	1	3
2018	0	1	1
2019	1	2	3
2020	1	0	1
2021	0	1	1
2022	1	2	3
2023	0	2	2

Below are the most recent publications written about "Chemokines" by people in Profiles.

Adinew GM, Messeha S, Taka E, Mochona B, Redda KK, Soliman KFA. Thymoquinone Inhibition of Chemokines in TNF-a-Induced Inflammatory and Metastatic Effects in Triple-Negative Breast Cancer Cells. Int J Mol Sci. 2023 Jun 08; 24(12).

View in: PubMed
Kroll KW, Woolley G, Terry K, Premeaux TA, Shikuma CM, Corley MJ, Bowler S, Ndhlovu LC, Reeves RK. Multiplex Analysis of Cytokines and Chemokines in Persons Aging With or Without HIV. AIDS Res Hum Retroviruses. 2023 07; 39(7):367-380.

View in: PubMed
Banerjee S, Mishra S, Xu W, Thompson WE, Chowdhury I. Neuregulin-1 signaling regulates cytokines and chemokines expression and secretion in granulosa cell. J Ovarian Res. 2022 Jul 26; 15(1):86.

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Wang LT, Wang YJ, Zhang YX, Chen SJ, Liu ZX, Cao JY, Ni WJ, Tang TT, Tang RN, Zhang XL, Liu BC. High phosphorus mediated the release of C-X-C motif chemokine ligand 8 in valvular interstitial cells-induced endothelial-to-mesenchymal transition via miR-214/phosphatase and tensin homolog to promote valvular calcification in chronic kidney disease. Clin Transl Med. 2022 05; 12(5):e733.

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Singh SK, Singh R. Cytokines and Chemokines in Cancer Cachexia and Its Long-Term Impact on COVID-19. Cells. 2022 02 08; 11(3).

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Keck J, Chambers JP, Yu JJ, Cheng X, Christenson LK, Guentzel MN, Gupta R, Arulanandam BP. Modulation of Immune Response to Chlamydia muridarum by Host miR-135a. Front Cell Infect Microbiol. 2021; 11:638058.

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Adekoya TO, Richardson RM. Cytokines and Chemokines as Mediators of Prostate Cancer Metastasis. Int J Mol Sci. 2020 Jun 23; 21(12).

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Tiwari S, Casey R, Goulding CW, Hingley-Wilson S, Jacobs WR. Infect and Inject: How Mycobacterium tuberculosis Exploits Its Major Virulence-Associated Type VII Secretion System, ESX-1. Microbiol Spectr. 2019 05; 7(3).

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Bagnall-Moreau C, Chaudhry S, Salas-Ramirez K, Ahles T, Hubbard K. Chemotherapy-Induced Cognitive Impairment Is Associated with Increased Inflammation and Oxidative Damage in the Hippocampus. Mol Neurobiol. 2019 Oct; 56(10):7159-7172.

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Jenkins BD, Martini RN, Hire R, Brown A, Bennett B, Brown I, Howerth EW, Egan M, Hodgson J, Yates C, Kittles R, Chitale D, Ali H, Nathanson D, Nikolinakos P, Newman L, Monteil M, Davis MB. Atypical Chemokine Receptor 1 (DARC/ACKR1) in Breast Tumors Is Associated with Survival, Circulating Chemokines, Tumor-Infiltrating Immune Cells, and African Ancestry. Cancer Epidemiol Biomarkers Prev. 2019 04; 28(4):690-700.

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