Hepatocyte Growth Factor

"Hepatocyte Growth Factor" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure, which enables searching at various levels of specificity.

MeSH information

Definition | Details | More General Concepts | Related Concepts | More Specific Concepts

Multifunctional growth factor which regulates both cell growth and cell motility. It exerts a strong mitogenic effect on hepatocytes and primary epithelial cells. Its receptor is PROTO-ONCOGENE PROTEINS C-MET.

Descriptor ID	D017228
MeSH Number(s)	D12.644.276.374.420 D12.776.467.374.420 D23.529.374.420
Concept/Terms	Hepatocyte Growth Factor Hepatocyte Growth Factor Factor, Hepatocyte Growth Growth Factor, Hepatocyte Scatter Factor Factor, Scatter Hepatopoietin Hepatopoietin A

Below are MeSH descriptors whose meaning is more general than "Hepatocyte Growth Factor".

Chemicals and Drugs [D]
Amino Acids, Peptides, and Proteins [D12]
Peptides [D12.644]
Intercellular Signaling Peptides and Proteins [D12.644.276]
Cytokines [D12.644.276.374]
Hepatocyte Growth Factor [D12.644.276.374.420]
Proteins [D12.776]
Intercellular Signaling Peptides and Proteins [D12.776.467]
Cytokines [D12.776.467.374]
Hepatocyte Growth Factor [D12.776.467.374.420]
Biological Factors [D23]
Intercellular Signaling Peptides and Proteins [D23.529]
Cytokines [D23.529.374]
Hepatocyte Growth Factor [D23.529.374.420]

Below are MeSH descriptors whose meaning is related to "Hepatocyte Growth Factor".

Below are MeSH descriptors whose meaning is more specific than "Hepatocyte Growth Factor".

publications

Timeline | Most Recent

This graph shows the total number of publications written about "Hepatocyte Growth Factor" by people in this website by year, and whether "Hepatocyte Growth Factor" was a major or minor topic of these publications.

Bar chart showing 16 publications over 12 distinct years, with a maximum of 3 publications in 2013

To see the data from this visualization as text, click here.

Year	Major Topic	Minor Topic	Total
2007	1	1	2
2010	1	0	1
2011	1	0	1
2012	0	1	1
2013	2	1	3
2015	0	1	1
2016	0	1	1
2017	1	1	2
2021	1	0	1
2022	1	0	1
2024	0	1	1
2025	1	0	1

Below are the most recent publications written about "Hepatocyte Growth Factor" by people in Profiles.

Kittur FS, Mahmood Q, Saravanan M, Cheng Q, Xie J. Constitutive expression of a 34?kDa Mst1 fragment in the forebrain distinct from the caspase 3-cleaved isoform. Int J Biol Macromol. 2025 Aug; 319(Pt 4):145651.

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Jones VT, Graves-Deal R, Cao Z, Bogatcheva G, Ramirez MA, Harmych SJ, Higginbotham JN, Sharma V, Damalanka VC, Wahoski CC, Joshi N, Irudayam MJ, Roland JT, Ayers GD, Liu Q, Coffey RJ, Janetka JW, Singh B. Inhibition of autocrine HGF maturation overcomes cetuximab resistance in colorectal cancer. Cell Mol Life Sci. 2024 Jan 12; 81(1):28.

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Jones GS, Hoadley KA, Benefield H, Olsson LT, Hamilton AM, Bhattacharya A, Kirk EL, Tipaldos HJ, Fleming JM, Williams KP, Love MI, Nichols HB, Olshan AF, Troester MA. Racial differences in breast cancer outcomes by hepatocyte growth factor pathway expression. Breast Cancer Res Treat. 2022 Apr; 192(2):447-455.

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Nekhai S, Lin X, Soni S, Taye A, Smith N, Afangbedji N, Saraf SL, Gordeuk VR, Taylor JG, Jerebtsova M. Urinary Kringle Domain-Containing Protein HGFL: A Validated Biomarker of Early Sickle Cell Anemia-Associated Kidney Disease. Am J Nephrol. 2021; 52(7):582-587.

View in: PubMed
Jeong GH, Boisvert WA, Xi MZ, Zhang YL, Choi YB, Cho S, Lee S, Choi C, Lee BH. Effect of Miscanthus sinensis var. purpurascens Flower Extract on Proliferation and Molecular Regulation in Human Dermal Papilla Cells and Stressed C57BL/6 Mice. Chin J Integr Med. 2018 Aug; 24(8):591-599.

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Li X, He L, Yue Q, Lu J, Kang N, Xu X, Wang H, Zhang H. MiR-9-5p promotes MSC migration by activating ?-catenin signaling pathway. Am J Physiol Cell Physiol. 2017 Jul 01; 313(1):C80-C93.

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Boisvert WA, Yu M, Choi Y, Jeong GH, Zhang YL, Cho S, Choi C, Lee S, Lee BH. Hair growth-promoting effect of Geranium sibiricum extract in human dermal papilla cells and C57BL/6 mice. BMC Complement Altern Med. 2017 Feb 13; 17(1):109.

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Song M, He Y, Zhou H, Zhang Y, Li X, Yu Y. Combined analysis of DNA methylome and transcriptome reveal novel candidate genes with susceptibility to bovine Staphylococcus aureus subclinical mastitis. Sci Rep. 2016 07 14; 6:29390.

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Hamilton KE, Chatterji P, Lundsmith ET, Andres SF, Giroux V, Hicks PD, Noubissi FK, Spiegelman VS, Rustgi AK. Loss of Stromal IMP1 Promotes a Tumorigenic Microenvironment in the Colon. Mol Cancer Res. 2015 Nov; 13(11):1478-86.

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Bissonette GB, Bae MH, Suresh T, Jaffe DE, Powell EM. Prefrontal cognitive deficits in mice with altered cerebral cortical GABAergic interneurons. Behav Brain Res. 2014 Feb 01; 259:143-51.

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