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Sergei Nekhai

TitleProfessor
Faculty RankProfessor
InstitutionHoward University
DepartmentMedicine
Address1840 7th street, NW HURB-1, Rm.203_
Washington DC 20001
Phone2028654545
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    R25HL003679     (NEKHAI, SERGEI)Sep 30, 1996 - Aug 31, 2012
    NIH
    Howard University Research Scientist Award
    Role: Principal Investigator
    R21AI056973     (NEKHAI, SERGEI)Jul 1, 2003 - Jun 30, 2007
    NIH
    REGULATION OF HIV-1 TRANSCRIPTION BY CDK2
    Role: Principal Investigator
    SC1GM082325     (NEKHAI, SERGEI)Apr 1, 2008 - Mar 31, 2014
    NIH
    Regulation of HIV-1 Transcription by CDK2
    Role: Principal Investigator
    P50HL118006     (NEKHAI, SERGEI)Aug 22, 2013 - Dec 31, 2020
    NIH
    Center for Hemoglobin Research in Minorities (CHaRM)
    Role: Principal Investigator
    R01HL125005     (NEKHAI, SERGEI)May 5, 2014 - Feb 28, 2025
    NIH
    Sickle Cell Disease and Sickle Cell Trait Protection Against HIV-1-infection in Africans and African Americans
    Role: Principal Investigator
    R13HL138729     (FRANK, MARTIN)Sep 1, 2017 - Aug 31, 2018
    NIH
    Conference on Physiology and Pathophysiology of Sickle Cell Disease
    Role: Co-Principal Investigator
    S10OD028681     (NEKHAI, SERGEI)Sep 10, 2020 - Sep 9, 2021
    NIH
    Acquisition of Orbitrap mass spectrometer
    Role: Principal Investigator

    Collapse Bibliographic 
    Collapse selected publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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    PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Fortuna V, Lima J, Oliveira GF, Oliveira YS, Getachew B, Nekhai S, Aschner M, Tizabi Y. Ferroptosis as an emerging target in sickle cell disease. Curr Res Toxicol. 2024; 7:100181. PMID: 39021403.
      Citations:    
    2. Keener R, Chhetri SB, Connelly CJ, Taub MA, Conomos MP, Weinstock J, Ni B, Strober B, Aslibekyan S, Auer PL, Barwick L, Becker LC, Blangero J, Bleecker ER, Brody JA, Cade BE, Celedon JC, Chang YC, Cupples LA, Custer B, Freedman BI, Gladwin MT, Heckbert SR, Hou L, Irvin MR, Isasi CR, Johnsen JM, Kenny EE, Kooperberg C, Minster RL, Naseri T, Viali S, Nekhai S, Pankratz N, Peyser PA, Taylor KD, Telen MJ, Wu B, Yanek LR, Yang IV, Albert C, Arnett DK, Ashley-Koch AE, Barnes KC, Bis JC, Blackwell TW, Boerwinkle E, Burchard EG, Carson AP, Chen Z, Chen YI, Darbar D, de Andrade M, Ellinor PT, Fornage M, Gelb BD, Gilliland FD, He J, Islam T, Kaab S, Kardia SLR, Kelly S, Konkle BA, Kumar R, Loos RJF, Martinez FD, McGarvey ST, Meyers DA, Mitchell BD, Montgomery CG, North KE, Palmer ND, Peralta JM, Raby BA, Redline S, Rich SS, Roden D, Rotter JI, Ruczinski I, Schwartz D, Sciurba F, Shoemaker MB, Silverman EK, Sinner MF, Smith NL, Smith AV, Tiwari HK, Vasan RS, Weiss ST, Williams LK, Zhang Y, Ziv E, Raffield LM, Reiner AP, Arvanitis M, Greider CW, Mathias RA, Battle A. Validation of human telomere length multi-ancestry meta-analysis association signals identifies POP5 and KBTBD6 as human telomere length regulation genes. Nat Commun. 2024 May 24; 15(1):4417. PMID: 38789417.
      Citations: 1     Fields:    Translation:HumansCells
    3. Bracci N, Baer A, Flor R, Petraccione K, Stocker T, Zhou W, Ammosova T, Dinglasan RR, Nekhai S, Kehn-Hall K. CK1 and PP1 regulate Rift Valley fever virus genome replication through L protein phosphorylation. Antiviral Res. 2024 Jun; 226:105895. PMID: 38679165.
      Citations:    Fields:    Translation:HumansAnimalsCells
    4. Packialakshmi B, Limerick E, Ackerman HC, Lin X, Nekhai S, Oliver JD, Stewart IJ, Knepper MA, Fitzhugh C, Zhou X. Proteomic analyses of urinary exosomes identify novel potential biomarkers for early diagnosis of sickle cell nephropathy, a sex-based study. Front Physiol. 2024; 15:1300667. PMID: 38426210.
      Citations:    
    5. Kumari N, Ahmad A, Berto-Junior C, Ivanov A, Wen F, Lin X, Diaz S, Okpala I, Taylor JG, Jerebtsova M, Nekhai S. Antiviral response and HIV-1 inhibition in sickle cell disease. iScience. 2024 Feb 16; 27(2):108813. PMID: 38318349.
      Citations:    
    6. Ogundiran AI, Chang T-L, Ivanov A, Kumari N, Nekhai S, Chandran PL. Shear-reversible clusters of HIV-1 in solution: stabilized by antibodies, dispersed by mucin. J Virol. 2023 10 31; 97(10):e0075223. PMID: 37712704.
      Citations:    Fields:    Translation:HumansCells
    7. Zhang X, Song J, Shah BN, Han J, Hassan T, Miasniakova G, Sergueeva A, Nekhai S, Machado RF, Gladwin MT, Saraf SL, Prchal JT, Gordeuk VR. Publisher Correction: Gene expression changes in sickle cell reticulocytes and their clinical associations. Sci Rep. 2023 Sep 14; 13(1):15225. PMID: 37709839.
      Citations:    Fields:    
    8. Zhang X, Song J, Shah BN, Han J, Hassan T, Miasniakova G, Sergueeva A, Nekhai S, Machado RF, Gladwin MT, Saraf SL, Prchal JT, Gordeuk VR. Gene expression changes in sickle cell reticulocytes and their clinical associations. Sci Rep. 2023 08 08; 13(1):12864. PMID: 37553354.
      Citations:    Fields:    Translation:HumansCells
    9. Ahmad A, Kumari N, Afangbedji N, Nekhai S, Jerebtsova M. Induction of Hepcidin Expression in the Renal Cortex of Sickle Cell Disease Mice. Int J Mol Sci. 2023 Jun 28; 24(13). PMID: 37445980.
      Citations:    Fields:    Translation:AnimalsCells
    10. Castro-Sesquen YE, Saraf SL, Gordeuk VR, Nekhai S, Jerebtsova M. Use of multiple urinary biomarkers for the early detection of chronic kidney disease in sickle cell anemia. Blood Adv. 2023 06 13; 7(11):2606-2608. PMID: 36634264.
      Citations:    Fields:    Translation:Humans
    11. Ahmad A, Tigabu B, Ivanov A, Jerebtsova M, Ammosova T, Ramanathan P, Kumari N, Brantner CA, Pietzsch CA, Abdullah G, Popratiloff A, Widen S, Bukreyev A, Nekhai S. Ebola Virus NP Binding to Host Protein Phosphatase-1 Regulates Capsid Formation. Res Sq. 2023 Jun 06. PMID: 37333330.
      Citations:    
    12. Afangbedji N, Kumari N, Diaz S, Wen F, Taylor JG, Nekhai S, Jerebtsova M. Soluble urokinase-type plasminogen activator receptor in sickle cell disease-associated chronic kidney disease. Blood Adv. 2023 05 09; 7(9):1854-1857. PMID: 36103150.
      Citations: 2     Fields:    Translation:HumansCells
    13. Earley EJ, Kelly S, Fang F, Alencar CS, Rodrigues DOW, Soares Cruz DT, Flanagan JM, Ware RE, Zhang X, Gordeuk V, Gladwin M, Zhang Y, Nouraie M, Nekhai S, Sabino E, Custer B, Dinardo C, Page GP. Genome-wide association study of early ischaemic stroke risk in Brazilian individuals with sickle cell disease implicates ADAMTS2 and CDK18 and uncovers novel loci. Br J Haematol. 2023 04; 201(2):343-352. PMID: 36602125.
      Citations: 1     Fields:    Translation:Humans
    14. Lin X, Ahmad A, Ivanov AI, Simhadri J, Wang S, Kumari N, Ammosova T, Nekhai S. HIV-1 Transcription Inhibitor 1E7-03 Decreases Nucleophosmin Phosphorylation. Mol Cell Proteomics. 2023 02; 22(2):100488. PMID: 36563749.
      Citations:    Fields:    Translation:HumansAnimalsCells
    15. Okpala I, Chukwuka C, Nouraie S, Nekhai S, Onwuka C, Hezekiah I, Obodo O, Maisamari D, Okereke K, Oden A, Tanko Y, Ezekekwu C, Kwaghi V, Onyedum C, Nnodu O. Effect of Sickle Cell Trait on Human Immunodeficiency Virus Type 1 Infection. Open AIDS J. 2022; 16. PMID: 36685019.
      Citations:    
    16. Nekhai S, Kumari N. HIV-1 infection in sickle cell disease and sickle cell trait: role of iron and innate response. Expert Rev Hematol. 2022 03; 15(3):253-263. PMID: 35322747.
      Citations: 3     Fields:    Translation:HumansCells
    17. Taub MA, Conomos MP, Keener R, Iyer KR, Weinstock JS, Yanek LR, Lane J, Miller-Fleming TW, Brody JA, Raffield LM, McHugh CP, Jain D, Gogarten SM, Laurie CA, Keramati A, Arvanitis M, Smith AV, Heavner B, Barwick L, Becker LC, Bis JC, Blangero J, Bleecker ER, Burchard EG, Celed?n JC, Chang YPC, Custer B, Darbar D, de Las Fuentes L, DeMeo DL, Freedman BI, Garrett ME, Gladwin MT, Heckbert SR, Hidalgo BA, Irvin MR, Islam T, Johnson WC, Kaab S, Launer L, Lee J, Liu S, Moscati A, North KE, Peyser PA, Rafaels N, Seidman C, Weeks DE, Wen F, Wheeler MM, Williams LK, Yang IV, Zhao W, Aslibekyan S, Auer PL, Bowden DW, Cade BE, Chen Z, Cho MH, Cupples LA, Curran JE, Daya M, Deka R, Eng C, Fingerlin TE, Guo X, Hou L, Hwang SJ, Johnsen JM, Kenny EE, Levin AM, Liu C, Minster RL, Naseri T, Nouraie M, Reupena MS, Sabino EC, Smith JA, Smith NL, Su JL, Taylor JG, Telen MJ, Tiwari HK, Tracy RP, White MJ, Zhang Y, Wiggins KL, Weiss ST, Vasan RS, Taylor KD, Sinner MF, Silverman EK, Shoemaker MB, Sheu WH, Sciurba F, Schwartz DA, Rotter JI, Roden D, Redline S, Raby BA, Psaty BM, Peralta JM, Palmer ND, Nekhai S, Montgomery CG, Mitchell BD, Meyers DA, McGarvey ST, Mak AC, Loos RJ, Kumar R, Kooperberg C, Konkle BA, Kelly S, Kardia SL, Kaplan R, He J, Gui H, Gilliland FD, Gelb BD, Fornage M, Ellinor PT, de Andrade M, Correa A, Chen YI, Boerwinkle E, Barnes KC, Ashley-Koch AE, Arnett DK, Laurie CC, Abecasis G, Nickerson DA, Wilson JG, Rich SS, Levy D, Ruczinski I, Aviv A, Blackwell TW, Thornton T, O'Connell J, Cox NJ, Perry JA, Armanios M, Battle A, Pankratz N, Reiner AP, Mathias RA. Genetic determinants of telomere length from 109,122 ancestrally diverse whole-genome sequences in TOPMed. Cell Genom. 2022 01 12; 2(1). PMID: 35530816.
      Citations: 24     Fields:    
    18. Kumari N, Nouraie M, Ahmad A, Lassiter H, Khan J, Diaz S, Afangbedji N, Wang S, Houston PE, Ammosova T, de Mulder Rougvie M, Rana S, Nixon DF, Anastos K, Lazar J, French AL, Gange S, Adimora AA, Weitzmann MN, Fischl M, Kempf MC, Kassaye S, Taylor JG, Nekhai S. Restriction of HIV-1 infection in sickle cell trait. Blood Adv. 2021 12 14; 5(23):4922-4934. PMID: 34496009.
      Citations: 2     Fields:    Translation:HumansCells
    19. Pushkarsky T, Ward A, Ivanov A, Lin X, Sviridov D, Nekhai S, Bukrinsky MI. Abundance of Nef and p-Tau217 in Brains of Individuals Diagnosed with HIV-Associated Neurocognitive Disorders Correlate with Disease Severance. Mol Neurobiol. 2022 Feb; 59(2):1088-1097. PMID: 34843091.
      Citations: 6     Fields:    Translation:Humans
    20. Alanazi A, Ivanov A, Kumari N, Lin X, Wang S, Kovalskyy D, Nekhai S. Targeting Tat-TAR RNA Interaction for HIV-1 Inhibition. Viruses. 2021 10 06; 13(10). PMID: 34696435.
      Citations: 5     Fields:    Translation:HumansCells
    21. Brim H, Taylor J, Abbas M, Vilmenay K, Daremipouran M, Varma S, Lee E, Pace B, Song-Naba WL, Gupta K, Nekhai S, O'Neil P, Ashktorab H. The gut microbiome in sickle cell disease: Characterization and potential implications. PLoS One. 2021; 16(8):e0255956. PMID: 34432825.
      Citations: 16     Fields:    Translation:HumansAnimalsCells
    22. Nekhai S, Lin X, Soni S, Taye A, Smith N, Afangbedji N, Saraf SL, Gordeuk VR, Taylor JG, Jerebtsova M. Urinary Kringle Domain-Containing Protein HGFL: A Validated Biomarker of Early Sickle Cell Anemia-Associated Kidney Disease. Am J Nephrol. 2021; 52(7):582-587. PMID: 34375971.
      Citations: 3     Fields:    Translation:HumansCells
    23. Stecher C, Marinkov S, Mayr-Harting L, Katic A, Kastner MT, Rieder-Rommer FJJ, Lin X, Nekhai S, Steininger C. Protein Phosphatase 1 Regulates Human Cytomegalovirus Protein Translation by Restraining AMPK Signaling. Front Microbiol. 2021; 12:698603. PMID: 34335531.
      Citations:    
    24. Lin X, Sajith AM, Wang S, Kumari N, Choy MS, Ahmad A, Cadet DR, Gu X, Ivanov AI, Peti W, Kulkarni A, Nekhai S. Structural Optimization of 2,3-Dihydro-1H-cyclopenta[b]quinolines Targeting the Noncatalytic RVxF Site of Protein Phosphatase 1 for HIV-1 Inhibition. ACS Infect Dis. 2020 12 11; 6(12):3190-3211. PMID: 33258581.
      Citations: 4     Fields:    Translation:HumansCells
    25. Ogharandukun E, Tewolde W, Damtae E, Wang S, Ivanov A, Kumari N, Nekhai S, Chandran PL. Establishing Rules for Self-Adhesion and Aggregation of N-Glycan Sugars Using Virus Glycan Shields. Langmuir. 2020 11 24; 36(46):13769-13783. PMID: 33186493.
      Citations: 3     Fields:    Translation:Cells
    26. Niu X, Parry CS, Mason A, Harrison B, Nouraie SM, Ammosova T, Salomon-Andonie J, Oneal PA, Gordeuk VR, Taylor JG, Nekhai S. Prevalence of Sickle Cell Trait and Rare Hemoglobin Variants in the Metropolitan Washington DC Area. J Hematol. 2020 Sep; 9(3):93-95. PMID: 32855759.
      Citations:    
    27. Zhang X, Kershaw KN, Minniti CP, Campbell A, Rana SR, Darbari DS, Luchtman-Jones L, Sable C, Dham N, Ensing G, Arteta M, Taylor JG, Hsu LL, Nekhai S, Gordeuk VR. Influence of single parenthood on cardiopulmonary function in pediatric patients with sickle cell anemia. Blood Adv. 2020 07 28; 4(14):3311-3314. PMID: 32706890.
      Citations: 1     Fields:    Translation:Humans
    28. Zhang X, Song J, Shah BN, Nekhai S, Miasnikova G, Sergueeva A, Prchal JT, Gordeuk VR. Peripheral blood mononuclear cells show prominent gene expression by erythroid progenitors in diseases characterized by heightened erythropoiesis. Br J Haematol. 2020 07; 190(1):e42-e45. PMID: 32399971.
      Citations: 2     Fields:    Translation:HumansCells
    29. Jerebtsova M, Taye A, Smith N, Afangbedji N, Stokes D, Niu X, Diaz S, Taylor JG, Nekhai S. Association between plasma and urinary orosomucoid and chronic kidney disease in adults with sickle cell disease. Br J Haematol. 2020 07; 190(1):e45-e48. PMID: 32372411.
      Citations: 7     Fields:    Translation:Humans
    30. Nouraie M, Darbari DS, Rana S, Minniti CP, Castro OL, Luchtman-Jones L, Sable C, Dham N, Kato GJ, Gladwin MT, Ensing G, Arteta M, Campbell A, Taylor JG, Nekhai S, Gordeuk VR. Tricuspid regurgitation velocity and other biomarkers of mortality in children, adolescents and young adults with sickle cell disease in the United States: The PUSH study. Am J Hematol. 2020 07; 95(7):766-774. PMID: 32243618.
      Citations: 11     Fields:    Translation:HumansCellsCTClinical Trials
    31. Liu W, Zhang S, Nekhai S, Liu S. Depriving Iron Supply to the Virus Represents a Promising Adjuvant Therapeutic Against Viral Survival. Curr Clin Microbiol Rep. 2020; 7(2):13-19. PMID: 32318324.
      Citations:    
    32. Jerebtsova M, Ahmad A, Kumari N, Rutagarama O, Nekhai S. Macrophage HIV-1 Gene Expression and Delay Resolution of Inflammation in HIV-Tg Mice. Viruses. 2020 03 01; 12(3). PMID: 32121564.
      Citations: 2     Fields:    Translation:HumansAnimalsCells
    33. Jerebtsova M, Ahmad A, Niu X, Rutagarama O, Nekhai S. HIV-1 Transcription Inhibitor 1E7-03 Restores LPS-Induced Alteration of Lung Leukocytes' Infiltration Dynamics and Resolves Inflammation in HIV Transgenic Mice. Viruses. 2020 02 12; 12(2). PMID: 32059509.
      Citations: 4     Fields:    Translation:AnimalsCells
    34. Zhang X, Shah BN, Zhang W, Saraf SL, Nouraie M, Nekhai S, Machado RF, Gladwin MT, Gordeuk VR. S100B has pleiotropic effects on vaso-occlusive manifestations in sickle cell disease. Am J Hematol. 2020 03; 95(3):E62-E65. PMID: 31805207.
      Citations: 2     Fields:    Translation:Humans
    35. Younan P, Santos RI, Ramanathan P, Iampietro M, Nishida A, Dutta M, Ammosova T, Meyer M, Katze MG, Popov VL, Nekhai S, Bukreyev A. Ebola virus-mediated T-lymphocyte depletion is the result of an abortive infection. PLoS Pathog. 2019 10; 15(10):e1008068. PMID: 31648236.
      Citations: 27     Fields:    Translation:HumansAnimalsCells
    36. Ivanov A, Ramanathan P, Parry C, Ilinykh PA, Lin X, Petukhov M, Obukhov Y, Ammosova T, Amarasinghe GK, Bukreyev A, Nekhai S. Global phosphoproteomic analysis of Ebola virions reveals a novel role for VP35 phosphorylation-dependent regulation of genome transcription. Cell Mol Life Sci. 2020 Jul; 77(13):2579-2603. PMID: 31562565.
      Citations: 5     Fields:    Translation:HumansAnimalsCells
    37. Lin X, Ammosova T, Choy MS, Pietzsch CA, Ivanov A, Ahmad A, Saygideger Y, Kumari N, Kovalskyy D, ?ren A, Peti W, Bukreyev A, Nekhai S. Targeting the Non-catalytic RVxF Site of Protein Phosphatase-1 With Small Molecules for Ebola Virus Inhibition. Front Microbiol. 2019; 10:2145. PMID: 31572348.
      Citations:    
    38. Dokekias AE, Ngolet L, Salomon-Andonie J, Nekhai S, Taylor JG. Establishing a national sickle cell disease program in the Republic of Congo. Blood Adv. 2018 11 30; 2(Suppl 1):17-18. PMID: 30504190.
      Citations: 1     Fields:    Translation:Humans
    39. Ammosova T, Pietzsch CA, Saygideger Y, Ilatovsky A, Lin X, Ivanov A, Kumari N, Jerebtsova M, Kulkarni A, Petukhov M, ?ren A, Bukreyev A, Nekhai S. Protein Phosphatase 1-Targeting Small-Molecule C31 Inhibits Ebola Virus Replication. J Infect Dis. 2018 11 22; 218(suppl_5):S627-S635. PMID: 30169869.
      Citations: 8     Fields:    Translation:HumansAnimalsCells
    40. Tigabu B, Ramanathan P, Ivanov A, Lin X, Ilinykh PA, Parry CS, Freiberg AN, Nekhai S, Bukreyev A. Phosphorylated VP30 of Marburg Virus Is a Repressor of Transcription J Virol. 2018 11 01; 92(21). PMID: 30135121.
      Citations: 13     Fields:    Translation:HumansAnimalsCells
    41. Carey BD, Ammosova T, Pinkham C, Lin X, Zhou W, Liotta LA, Nekhai S, Kehn-Hall K. Protein Phosphatase 1a Interacts with Venezuelan Equine Encephalitis Virus Capsid Protein and Regulates Viral Replication through Modulation of Capsid Phosphorylation. J Virol. 2018 08 01; 92(15). PMID: 29769351.
      Citations: 7     Fields:    Translation:AnimalsCells
    42. Ivanov A, Lin X, Ammosova T, Ilatovskiy AV, Kumari N, Lassiter H, Afangbedji N, Niu X, Petukhov MG, Nekhai S. HIV-1 Tat phosphorylation on Ser-16 residue modulates HIV-1 transcription. Retrovirology. 2018 05 23; 15(1):39. PMID: 29792216.
      Citations: 8     Fields:    Translation:HumansCells
    43. Du M, Van Ness S, Gordeuk V, Nouraie SM, Nekhai S, Gladwin M, Steinberg MH, Sebastiani P. Biomarker signatures of sickle cell disease severity. Blood Cells Mol Dis. 2018 09; 72:1-9. PMID: 29778312.
      Citations: 12     Fields:    Translation:Humans
    44. Pleet ML, Mathiesen A, DeMarino C, Akpamagbo YA, Barclay RA, Schwab A, Iordanskiy S, Sampey GC, Lepene B, Ilinykh PA, Bukreyev A, Nekhai S, Aman MJ, Kashanchi F. Corrigendum: Ebola VP40 in Exosomes Can Cause Immune Cell Dysfunction. Front Microbiol. 2018; 9:692. PMID: 29696006.
      Citations:    
    45. Khaibullina A, Adjei EA, Afangbedji N, Ivanov A, Kumari N, Almeida LEF, Quezado ZMN, Nekhai S, Jerebtsova M. RON kinase inhibition reduces renal endothelial injury in sickle cell disease mice. Haematologica. 2018 05; 103(5):787-798. PMID: 29519868.
      Citations: 12     Fields:    Translation:HumansAnimalsCells
    46. Richard CA, Rincheval V, Lassoued S, Fix J, Cardone C, Esneau C, Nekhai S, Galloux M, Rameix-Welti MA, Sizun C, El?ou?t JF. RSV hijacks cellular protein phosphatase 1 to regulate M2-1 phosphorylation and viral transcription. PLoS Pathog. 2018 03; 14(3):e1006920. PMID: 29489893.
      Citations: 33     Fields:    Translation:HumansCells
    47. Jerebtsova M, Saraf SL, Soni S, Afangbedji N, Lin X, Raslan R, Gordeuk VR, Nekhai S. Urinary orosomucoid is associated with progressive chronic kidney disease stage in patients with sickle cell anemia. Am J Hematol. 2018 08; 93(4):E107-E109. PMID: 29327376.
      Citations: 11     Fields:    Translation:Humans
    48. Jerebtsova M, Saraf SL, Lin X, Lee G, Adjei EA, Kumari N, Afangbedji N, Raslan R, McLean C, Gordeuk VR, Nekhai S. Identification of ceruloplasmin as a biomarker of chronic kidney disease in urine of sickle cell disease patients by proteomic analysis. Am J Hematol. 2018 02; 93(2):E45-E47. PMID: 29127684.
      Citations: 14     Fields:    Translation:Humans
    49. Lin X, Kumari N, DeMarino C, Kont YS, Ammosova T, Kulkarni A, Jerebtsova M, Vazquez-Meves G, Ivanov A, Dmytro K, ?ren A, Kashanchi F, Nekhai S. Inhibition of HIV-1 infection in humanized mice and metabolic stability of protein phosphatase-1-targeting small molecule 1E7-03. Oncotarget. 2017 Sep 29; 8(44):76749-76769. PMID: 29100346.
      Citations: 9     Fields:    
    50. Sergueeva A, Miasnikova G, Shah BN, Song J, Lisina E, Okhotin DJ, Nouraie M, Nekhai S, Ammosova T, Niu XM, Prchal JT, Zhang X, Gordeuk VR. Prospective study of thrombosis and thrombospondin-1 expression in Chuvash polycythemia. Haematologica. 2017 05; 102(5):e166-e169. PMID: 28104701.
      Citations: 8     Fields:    Translation:Humans
    51. Lin X, Ammosova T, Kumari N, Nekhai S. Protein Phosphatase-1 -targeted Small Molecules, Iron Chelators and Curcumin Analogs as HIV-1 Antivirals. Curr Pharm Des. 2017; 23(28):4122-4132. PMID: 28677499.
      Citations: 8     Fields:    Translation:HumansAnimalsCells
    52. Kumari N, Ammosova T, Diaz S, Lin X, Niu X, Ivanov A, Jerebtsova M, Dhawan S, Oneal P, Nekhai S. Increased iron export by ferroportin induces restriction of HIV-1 infection in sickle cell disease. Blood Adv. 2016 Dec 27; 1(3):170-183. PMID: 28203649.
      Citations: 19     Fields:    
    53. Ammosova T, Washington K, Rotimi J, Kumari N, Smith KA, Niu X, Jerebtsova M, Nekhai S. Protein Phosphatase-1 Regulates Expression of Neuregulin-1. Biology (Basel). 2016 Dec 02; 5(4). PMID: 27918433.
      Citations:    
    54. Dai Y, Sangerman J, Nouraie M, Faller AD, Oneal P, Rock A, Owoyemi O, Niu X, Nekhai S, Maharaj D, Cui S, Taylor R, Steinberg M, Perrine S. Effects of hydroxyurea on F-cells in sickle cell disease and potential impact of a second fetal globin inducer. Am J Hematol. 2017 Jan; 92(1):E10-E11. PMID: 27766663.
      Citations: 4     Fields:    Translation:HumansCells
    55. Fluitt MB, Kumari N, Nunlee-Bland G, Nekhai S, Gambhir KK. miRNA-15a, miRNA-15b, and miRNA-499 are Reduced in Erythrocytes of Pre-Diabetic African-American Adults. Jacobs J Diabetes Endocrinol. 2016 Dec; 2(1). PMID: 29399662.
      Citations:    
    56. Pleet ML, Mathiesen A, DeMarino C, Akpamagbo YA, Barclay RA, Schwab A, Iordanskiy S, Sampey GC, Lepene B, Nekhai S, Aman MJ, Kashanchi F. Ebola VP40 in Exosomes Can Cause Immune Cell Dysfunction. Front Microbiol. 2016; 7:1765. PMID: 27872619.
      Citations:    
    57. Zhang X, Shah BN, Zhang W, Saraf SL, Miasnikova G, Sergueeva A, Ammosova T, Niu X, Nouraie M, Nekhai S, Castro O, Gladwin MT, Prchal JT, Garcia JG, Machado RF, Gordeuk VR. A genetic variation associated with plasma erythropoietin and a non-coding transcript of PRKAR1A in sickle cell disease. Hum Mol Genet. 2016 10 15; 25(20):4601-4609. PMID: 28173069.
      Citations: 4     Fields:    Translation:HumansCells
    58. Santos S, Obukhov Y, Nekhai S, Pushkarsky T, Brichacek B, Bukrinsky M, Iordanskiy S. Cellular minichromosome maintenance complex component 5 (MCM5) is incorporated into HIV-1 virions and modulates viral replication in the newly infected cells. Virology. 2016 10; 497:11-22. PMID: 27414250.
      Citations: 2     Fields:    Translation:HumansCells
    59. Ogunwuyi O, Kumari N, Smith KA, Bolshakov O, Adesina S, Gugssa A, Anderson WA, Nekhai S, Akala EO. Antiretroviral Drugs-Loaded Nanoparticles Fabricated by Dispersion Polymerization with Potential for HIV/AIDS Treatment. Infect Dis (Auckl). 2016; 9:21-32. PMID: 27013886.
      Citations:    
    60. Baer A, Shafagati N, Benedict A, Ammosova T, Ivanov A, Hakami RM, Terasaki K, Makino S, Nekhai S, Kehn-Hall K. Protein Phosphatase-1 regulates Rift Valley fever virus replication. Antiviral Res. 2016 Mar; 127:79-89. PMID: 26801627.
      Citations: 13     Fields:    Translation:HumansAnimalsCells
    61. Huang H, Konduru K, Solovena V, Zhou ZH, Kumari N, Takeda K, Nekhai S, Bavari S, Kaplan GG, Yamada KM, Dhawan S. Therapeutic potential of the heme oxygenase-1 inducer hemin against Ebola virus infection. Curr Trends Immunol. 2016; 17:117-123. PMID: 28133423.
      Citations:    
    62. Kumari N, Kulkarni AA, Lin X, McLean C, Ammosova T, Ivanov A, Hipolito M, Nekhai S, Nwulia E. Inhibition of HIV-1 by curcumin A, a novel curcumin analog. Drug Des Devel Ther. 2015; 9:5051-60. PMID: 26366056.
      Citations: 36     Fields:    Translation:HumansAnimalsCells
    63. Tyagi M, Iordanskiy S, Ammosova T, Kumari N, Smith K, Breuer D, Ilatovskiy AV, Kont YS, Ivanov A, ?ren A, Kovalskyy D, Petukhov M, Kashanchi F, Nekhai S. Reactivation of latent HIV-1 provirus via targeting protein phosphatase-1. Retrovirology. 2015 Jul 16; 12:63. PMID: 26178009.
      Citations: 18     Fields:    Translation:HumansCells
    64. Smith KA, Lin X, Bolshakov O, Griffin J, Niu X, Kovalskyy D, Ivanov A, Jerebtsova M, Taylor RE, Akala E, Nekhai S. Activation of HIV-1 with Nanoparticle-Packaged Small-Molecule Protein Phosphatase-1-Targeting Compound. Sci Pharm. 2015 Jul-Sep; 83(3):535-48. PMID: 26839837.
      Citations:    
    65. Zhang X, Zhang W, Saraf SL, Nouraie M, Han J, Gowhari M, Hassan J, Miasnikova G, Sergueeva A, Nekhai S, Kittles R, Machado RF, Garcia JG, Gladwin MT, Steinberg MH, Sebastiani P, McClain DA, Gordeuk VR. Genetic polymorphism of APOB is associated with diabetes mellitus in sickle cell disease. Hum Genet. 2015 Aug; 134(8):895-904. PMID: 26025476.
      Citations: 13     Fields:    Translation:Humans
    66. Jerebtsova M, Nekhai S. Therapeutics for postexposure treatment of Ebola virus infection. Future Virol. 2015 Mar; 10(3):221-232. PMID: 26213559.
      Citations:    
    67. Kassim OO, Copeland RL, Kenguele HM, Nekhai S, Ako-Nai KA, Kanaan YM. Antiproliferative activities of Fagara xanthoxyloides and Pseudocedrela kotschyi against prostate cancer cell lines. Anticancer Res. 2015 Mar; 35(3):1453-8. PMID: 25750297.
      Citations: 4     Fields:    Translation:HumansAnimalsCells
    68. Jerebtsova M, Nekhai S. Quantitative mass spectrometry of urinary biomarkers. J Integr OMICS. 2014 Dec 01; 4(2):69-78. PMID: 25984422.
      Citations:    
    69. van Beers EJ, Yang Y, Raghavachari N, Tian X, Allen DT, Nichols JS, Mendelsohn L, Nekhai S, Gordeuk VR, Taylor JG, Kato GJ. Iron, inflammation, and early death in adults with sickle cell disease. Circ Res. 2015 Jan 16; 116(2):298-306. PMID: 25378535.
      Citations: 40     Fields:    Translation:HumansCellsCTClinical Trials
    70. Ammosova T, Platonov M, Ivanov A, Kont YS, Kumari N, Kehn-Hall K, Jerebtsova M, Kulkarni AA, Uren A, Kovalskyy D, Nekhai S. 1E7-03, a low MW compound targeting host protein phosphatase-1, inhibits HIV-1 transcription. Br J Pharmacol. 2014 Nov; 171(22):5059-75. PMID: 25073485.
      Citations: 23     Fields:    Translation:AnimalsCells
    71. Kumari N, Iordanskiy S, Kovalskyy D, Breuer D, Niu X, Lin X, Xu M, Gavrilenko K, Kashanchi F, Dhawan S, Nekhai S. Phenyl-1-Pyridin-2yl-ethanone-based iron chelators increase I?B-a expression, modulate CDK2 and CDK9 activities, and inhibit HIV-1 transcription. Antimicrob Agents Chemother. 2014 Nov; 58(11):6558-71. PMID: 25155598.
      Citations: 11     Fields:    Translation:HumansCells
    72. Ilinykh PA, Tigabu B, Ivanov A, Ammosova T, Obukhov Y, Garron T, Kumari N, Kovalskyy D, Platonov MO, Naumchik VS, Freiberg AN, Nekhai S, Bukreyev A. Role of protein phosphatase 1 in dephosphorylation of Ebola virus VP30 protein and its targeting for the inhibition of viral transcription. J Biol Chem. 2014 Aug 15; 289(33):22723-22738. PMID: 24936058.
      Citations: 49     Fields:    Translation:HumansAnimalsCells
    73. Chasnyk V, Fedorova E, Egorov A, Ammosova T, Nekhai S, Kostik M, Santimov A, Dubko M, Kalashnikova O, Masalova V, Likhacheva T, Snegireva L, Grom A. A130: Is the CCR5-delta32 Mutation Protective Against Systemic-Onset Juvenile Idiopathic Arthritis? Arthritis Rheumatol. 2014 Mar; 66 Suppl 3:S171. PMID: 24677884.
      Citations: 1     Fields:    
    74. Zhang X, Zhang W, Ma SF, Desai AA, Saraf S, Miasniakova G, Sergueeva A, Ammosova T, Xu M, Nekhai S, Abbasi T, Casanova NG, Steinberg MH, Baldwin CT, Sebastiani P, Prchal JT, Kittles R, Garcia JG, Machado RF, Gordeuk VR. Hypoxic response contributes to altered gene expression and precapillary pulmonary hypertension in patients with sickle cell disease. Circulation. 2014 Apr 22; 129(16):1650-8. PMID: 24515990.
      Citations: 28     Fields:    Translation:HumansCells
    75. Nekhai S, Petukhov M, Breuer D. Regulation of CDK9 activity by phosphorylation and dephosphorylation. Biomed Res Int. 2014; 2014:964964. PMID: 24524087.
      Citations: 23     Fields:    Translation:HumansCells
    76. Ashenafi M, Ammosova T, Nekhai S, Byrnes WM. Purification and characterization of aminoglycoside phosphotransferase APH(6)-Id, a streptomycin-inactivating enzyme. Mol Cell Biochem. 2014 Feb; 387(1-2):207-16. PMID: 24248535.
      Citations: 11     Fields:    Translation:Cells
    77. Salomon-Andonie J, Miasnikova G, Sergueeva A, Polyakova LA, Niu X, Nekhai S, Gordeuk VR. Effect of congenital upregulation of hypoxia inducible factors on percentage of fetal hemoglobin in the blood. Blood. 2013 Oct 24; 122(17):3088-9. PMID: 24159170.
      Citations: 3     Fields:    Translation:Humans
    78. Zhang X, Zhang W, Ma SF, Miasniakova G, Sergueeva A, Ammosova T, Xu M, Nekhai S, Nourai M, Wade MS, Prchal JT, Garcia JGN, Machado RF, Gordeuk VR. Iron deficiency modifies gene expression variation induced by augmented hypoxia sensing. Blood Cells Mol Dis. 2014 Jan; 52(1):35-45. PMID: 23993337.
      Citations: 14     Fields:    Translation:HumansCells
    79. Zhou ZH, Kumari N, Nekhai S, Clouse KA, Wahl LM, Yamada KM, Dhawan S. Heme oxygenase-1 induction alters chemokine regulation and ameliorates human immunodeficiency virus-type-1 infection in lipopolysaccharide-stimulated macrophages. Biochem Biophys Res Commun. 2013 Jun 07; 435(3):373-7. PMID: 23665328.
      Citations: 12     Fields:    Translation:HumansCells
    80. Nekhai S, Kumari N, Dhawan S. Role of cellular iron and oxygen in the regulation of HIV-1 infection. Future Virol. 2013 Mar; 8(3):301-311. PMID: 23678366.
      Citations:    
    81. Tomasic NL, Piterkova L, Huff C, Bilic E, Yoon D, Miasnikova GY, Sergueeva AI, Niu X, Nekhai S, Gordeuk V, Prchal JT. The phenotype of polycythemia due to Croatian homozygous VHL (571C>G:H191D) mutation is different from that of Chuvash polycythemia (VHL 598C>T:R200W). Haematologica. 2013 Apr; 98(4):560-7. PMID: 23403324.
      Citations: 16     Fields:    Translation:HumansCells
    82. Zhou ZH, Kumari N, Catalano J, Nekhai S, Wise J, Yamada KM, Dhawan S. Heme oxygenase-1-mediated host cell response inhibits the susceptibility of prostate cancer cells to retroviral infection and retards their proliferation. Curr Trends Immunol. 2013 Jan; 14:53-56. PMID: 25620854.
      Citations:    
    83. Van Duyne R, Guendel I, Jaworski E, Sampey G, Klase Z, Chen H, Zeng C, Kovalskyy D, El Kouni MH, Lepene B, Patanarut A, Nekhai S, Price DH, Kashanchi F. Effect of mimetic CDK9 inhibitors on HIV-1-activated transcription. J Mol Biol. 2013 Feb 22; 425(4):812-29. PMID: 23247501.
      Citations: 20     Fields:    Translation:HumansAnimalsCells
    84. Breuer D, Kotelkin A, Ammosova T, Kumari N, Ivanov A, Ilatovskiy AV, Beullens M, Roane PR, Bollen M, Petukhov MG, Kashanchi F, Nekhai S. CDK2 regulates HIV-1 transcription by phosphorylation of CDK9 on serine 90. Retrovirology. 2012 Nov 09; 9:94. PMID: 23140174.
      Citations: 32     Fields:    Translation:HumansCells
    85. Nekhai S, Xu M, Foster A, Kasvosve I, Diaz S, Machado RF, Castro OL, Kato GJ, Taylor JG, Gordeuk VR. Reduced sensitivity of the ferroportin Q248H mutant to physiological concentrations of hepcidin. Haematologica. 2013 Mar; 98(3):455-63. PMID: 23065513.
      Citations: 11     Fields:    Translation:HumansCells
    86. Jerebtsova M, Kumari N, Obuhkov Y, Nekhai S. Adenoviral E4 gene stimulates secretion of pigmental epithelium derived factor (PEDF) that maintains long-term survival of human glomerulus-derived endothelial cells. Mol Cell Proteomics. 2012 Nov; 11(11):1378-88. PMID: 22915824.
      Citations: 3     Fields:    Translation:HumansAnimalsCells
    87. Debebe Z, Nekhai S, Ashenafi M, Lovejoy DB, Kalinowski DS, Gordeuk VR, Byrnes WM, Richardson DR, Karla PK. Development of a sensitive HPLC method to measure in vitro permeability of E- and Z-isomeric forms of thiosemicarbazones in Caco-2 monolayers. J Chromatogr B Analyt Technol Biomed Life Sci. 2012 Oct 01; 906:25-32. PMID: 22954966.
      Citations: 4     Fields:    Translation:HumansCells
    88. Santos S, Obukhov Y, Nekhai S, Bukrinsky M, Iordanskiy S. Virus-producing cells determine the host protein profiles of HIV-1 virion cores. Retrovirology. 2012 Aug 13; 9:65. PMID: 22889230.
      Citations: 43     Fields:    Translation:HumansCells
    89. Jerebtsova M, Kumari N, Xu M, de Melo GB, Niu X, Jeang KT, Nekhai S. HIV-1 Resistant CDK2-Knockdown Macrophage-Like Cells Generated from 293T Cell-Derived Human Induced Pluripotent Stem Cells. Biology (Basel). 2012 Jul 26; 1(2):175-195. PMID: 22934150.
      Citations:    
    90. Narayanan A, Sampey G, Van Duyne R, Guendel I, Kehn-Hall K, Roman J, Currer R, Galons H, Oumata N, Joseph B, Meijer L, Caputi M, Nekhai S, Kashanchi F. Use of ATP analogs to inhibit HIV-1 transcription. Virology. 2012 Oct 10; 432(1):219-31. PMID: 22771113.
      Citations: 13     Fields:    Translation:HumansCells
    91. Ammosova T, Platonov M, Yedavalli VR, Obukhov Y, Gordeuk VR, Jeang KT, Kovalskyy D, Nekhai S. Small molecules targeted to a non-catalytic "RVxF" binding site of protein phosphatase-1 inhibit HIV-1. PLoS One. 2012; 7(6):e39481. PMID: 22768081.
      Citations: 23     Fields:    Translation:HumansCells
    92. Nouraie M, Nekhai S, Gordeuk VR. Sickle cell disease is associated with decreased HIV but higher HBV and HCV comorbidities in U.S. hospital discharge records: a cross-sectional study. Sex Transm Infect. 2012 Nov; 88(7):528-33. PMID: 22628662.
      Citations: 19     Fields:    Translation:Humans
    93. Gordeuk VR, Miasnikova GY, Sergueeva AI, Niu X, Nouraie M, Okhotin DJ, Polyakova LA, Ammosova T, Nekhai S, Ganz T, Prchal JT. Chuvash polycythemia VHLR200W mutation is associated with down-regulation of hepcidin expression. Blood. 2011 Nov 10; 118(19):5278-82. PMID: 21876117.
      Citations: 24     Fields:    Translation:HumansCells
    94. Van Duyne R, Guendel I, Narayanan A, Gregg E, Shafagati N, Tyagi M, Easley R, Klase Z, Nekhai S, Kehn-Hall K, Kashanchi F. Varying modulation of HIV-1 LTR activity by Baf complexes. J Mol Biol. 2011 Aug 19; 411(3):581-96. PMID: 21699904.
      Citations: 29     Fields:    Translation:HumansCells
    95. Ammosova T, Obukhov Y, Kotelkin A, Breuer D, Beullens M, Gordeuk VR, Bollen M, Nekhai S. Protein phosphatase-1 activates CDK9 by dephosphorylating Ser175. PLoS One. 2011 Apr 21; 6(4):e18985. PMID: 21533037.
      Citations: 35     Fields:    Translation:HumansCells
    96. Thuma PE, van Dijk J, Bucala R, Debebe Z, Nekhai S, Kuddo T, Nouraie M, Weiss G, Gordeuk VR. Distinct clinical and immunologic profiles in severe malarial anemia and cerebral malaria in Zambia. J Infect Dis. 2011 Jan 15; 203(2):211-9. PMID: 21288821.
      Citations: 41     Fields:    Translation:HumansAnimals
    97. Xu M, Kashanchi F, Foster A, Rotimi J, Turner W, Gordeuk VR, Nekhai S. Hepcidin induces HIV-1 transcription inhibited by ferroportin. Retrovirology. 2010 Dec 02; 7:104. PMID: 21126372.
      Citations: 32     Fields:    Translation:HumansCells
    98. Ammosova T, Yedavalli VR, Niu X, Jerebtsova M, Van Eynde A, Beullens M, Bollen M, Jeang KT, Nekhai S. Expression of a protein phosphatase 1 inhibitor, cdNIPP1, increases CDK9 threonine 186 phosphorylation and inhibits HIV-1 transcription. J Biol Chem. 2011 Feb 04; 286(5):3798-804. PMID: 21098020.
      Citations: 37     Fields:    Translation:HumansAnimalsCells
    99. Debebe Z, Ammosova T, Breuer D, Lovejoy DB, Kalinowski DS, Kumar K, Jerebtsova M, Ray P, Kashanchi F, Gordeuk VR, Richardson DR, Nekhai S. Iron chelators of the di-2-pyridylketone thiosemicarbazone and 2-benzoylpyridine thiosemicarbazone series inhibit HIV-1 transcription: identification of novel cellular targets--iron, cyclin-dependent kinase (CDK) 2, and CDK9. Mol Pharmacol. 2011 Jan; 79(1):185-96. PMID: 20956357.
      Citations: 41     Fields:    Translation:HumansCells
    100. Jerebtsova M, Klotchenko SA, Artamonova TO, Ammosova T, Washington K, Egorov VV, Shaldzhyan AA, Sergeeva MV, Zatulovskiy EA, Temkina OA, Petukhov MG, Vasin AV, Khodorkovskii MA, Orlov YN, Nekhai S. Mass spectrometry and biochemical analysis of RNA polymerase II: targeting by protein phosphatase-1. Mol Cell Biochem. 2011 Jan; 347(1-2):79-87. PMID: 20941529.
      Citations: 17     Fields:    Translation:HumansCells
    101. Kasvosve I, Debebe Z, Nekhai S, Gordeuk VR. Ferroportin (SLC40A1) Q248H mutation is associated with lower circulating plasma tumor necrosis factor-alpha and macrophage migration inhibitory factor concentrations in African children. Clin Chim Acta. 2010 Sep 06; 411(17-18):1248-52. PMID: 20460119.
      Citations: 4     Fields:    Translation:Humans
    102. Charles S, Ammosova T, Cardenas J, Foster A, Rotimi J, Jerebtsova M, Ayodeji AA, Niu X, Ray PE, Gordeuk VR, Kashanchi F, Nekhai S. Regulation of HIV-1 transcription at 3% versus 21% oxygen concentration. J Cell Physiol. 2009 Nov; 221(2):469-79. PMID: 19626680.
      Citations: 19     Fields:    Translation:HumansCells
    103. Gordeuk VR, Campbell A, Rana S, Nouraie M, Niu X, Minniti CP, Sable C, Darbari D, Dham N, Onyekwere O, Ammosova T, Nekhai S, Kato GJ, Gladwin MT, Castro OL. Relationship of erythropoietin, fetal hemoglobin, and hydroxyurea treatment to tricuspid regurgitation velocity in children with sickle cell disease. Blood. 2009 Nov 19; 114(21):4639-44. PMID: 19724057.
      Citations: 33     Fields:    Translation:Humans
    104. Niu X, Miasnikova GY, Sergueeva AI, Polyakova LA, Okhotin DJ, Tuktanov NV, Nouraie M, Ammosova T, Nekhai S, Gordeuk VR. Altered cytokine profiles in patients with Chuvash polycythemia. Am J Hematol. 2009 Feb; 84(2):74-8. PMID: 19062180.
      Citations: 9     Fields:    Translation:Humans
    105. Gordeuk VR, Diaz SF, Onojobi GO, Kasvosve I, Debebe Z, Edossa A, Pantin JM, Xiong S, Nekhai S, Nouraie M, Tsukamoto H, Taylor RE. Ferroportin Q248h, dietary iron, and serum ferritin in community African-Americans with low to high alcohol consumption. Alcohol Clin Exp Res. 2008 Nov; 32(11):1947-53. PMID: 18782341.
      Citations: 6     Fields:    Translation:Humans
    106. Berro R, Pedati C, Kehn-Hall K, Wu W, Klase Z, Even Y, Genevi?re AM, Ammosova T, Nekhai S, Kashanchi F. CDK13, a new potential human immunodeficiency virus type 1 inhibitory factor regulating viral mRNA splicing. J Virol. 2008 Jul; 82(14):7155-66. PMID: 18480452.
      Citations: 34     Fields:    Translation:HumansCells
    107. Sergueeva AI, Miasnikova GY, Okhotin DJ, Levina AA, Debebe Z, Ammosova T, Niu X, Romanova EA, Nekhai S, DiBello PM, Jacobsen DW, Prchal JT, Gordeuk VR. Elevated homocysteine, glutathione and cysteinylglycine concentrations in patients homozygous for the Chuvash polycythemia VHL mutation. Haematologica. 2008 Feb; 93(2):279-82. PMID: 18223282.
      Citations: 7     Fields:    Translation:Humans
    108. Debebe Z, Ammosova T, Jerebtsova M, Kurantsin-Mills J, Niu X, Charles S, Richardson DR, Ray PE, Gordeuk VR, Nekhai S. Iron chelators ICL670 and 311 inhibit HIV-1 transcription. Virology. 2007 Oct 25; 367(2):324-33. PMID: 17631934.
      Citations: 36     Fields:    Translation:HumansCells
    109. Berro R, de la Fuente C, Klase Z, Kehn K, Parvin L, Pumfery A, Agbottah E, Vertes A, Nekhai S, Kashanchi F. Identifying the membrane proteome of HIV-1 latently infected cells. J Biol Chem. 2007 Mar 16; 282(11):8207-18. PMID: 17237230.
      Citations: 37     Fields:    Translation:HumansCells
    110. Nekhai S, Jerebtsova M, Jackson A, Southerland W. Regulation of HIV-1 transcription by protein phosphatase 1. Curr HIV Res. 2007 Jan; 5(1):3-9. PMID: 17266553.
      Citations: 23     Fields:    Translation:Cells
    111. Nekhai S, Bhat UG, Ammosova T, Radhakrishnan SK, Jerebtsova M, Niu X, Foster A, Layden TJ, Gartel AL. A novel anticancer agent ARC antagonizes HIV-1 and HCV. Oncogene. 2007 May 31; 26(26):3899-903. PMID: 17173067.
      Citations: 13     Fields:    Translation:HumansAnimalsCells
    112. Nekhai S, Jeang KT. Transcriptional and post-transcriptional regulation of HIV-1 gene expression: role of cellular factors for Tat and Rev. Future Microbiol. 2006 Dec; 1(4):417-26. PMID: 17661632.
      Citations: 53     Fields:    Translation:HumansCells
    113. Ammosova T, Berro R, Jerebtsova M, Jackson A, Charles S, Klase Z, Southerland W, Gordeuk VR, Kashanchi F, Nekhai S. Phosphorylation of HIV-1 Tat by CDK2 in HIV-1 transcription. Retrovirology. 2006 Nov 03; 3:78. PMID: 17083724.
      Citations: 55     Fields:    Translation:HumansCells
    114. Epie N, Ammosova T, Turner W, Nekhai S. Inhibition of PP2A by LIS1 increases HIV-1 gene expression. Retrovirology. 2006 Oct 02; 3:65. PMID: 17018134.
      Citations: 10     Fields:    Translation:HumansCells
    115. Bushuev VI, Miasnikova GY, Sergueeva AI, Polyakova LA, Okhotin D, Gaskin PR, Debebe Z, Nekhai S, Castro OL, Prchal JT, Gordeuk VR. Endothelin-1, vascular endothelial growth factor and systolic pulmonary artery pressure in patients with Chuvash polycythemia. Haematologica. 2006 Jun; 91(6):744-9. PMID: 16769575.
      Citations: 41     Fields:    Translation:Humans
    116. Kasvosve I, Gomo ZA, Nathoo KJ, Matibe P, Mudenge B, Loyevsky M, Nekhai S, Gordeuk VR. Association of serum transferrin receptor concentration with markers of inflammation in Zimbabwean children. Clin Chim Acta. 2006 Sep; 371(1-2):130-6. PMID: 16603144.
      Citations: 9     Fields:    Translation:HumansCells
    117. Nekhai S, Jerebtsova M. Therapies for HIV with RNAi. Curr Opin Mol Ther. 2006 Feb; 8(1):52-61. PMID: 16506526.
      Citations: 5     Fields:    Translation:HumansAnimalsCells
    118. Pumfery A, de la Fuente C, Berro R, Nekhai S, Kashanchi F, Chao SH. Potential use of pharmacological cyclin-dependent kinase inhibitors as anti-HIV therapeutics. Curr Pharm Des. 2006; 12(16):1949-61. PMID: 16787240.
      Citations: 15     Fields:    Translation:Humans
    119. Ammosova T, Jerebtsova M, Beullens M, Lesage B, Jackson A, Kashanchi F, Southerland W, Gordeuk VR, Bollen M, Nekhai S. Nuclear targeting of protein phosphatase-1 by HIV-1 Tat protein. J Biol Chem. 2005 Oct 28; 280(43):36364-71. PMID: 16131488.
      Citations: 36     Fields:    Translation:HumansCells
    120. Ammosova T, Berro R, Kashanchi F, Nekhai S. RNA interference directed to CDK2 inhibits HIV-1 transcription. Virology. 2005 Oct 25; 341(2):171-8. PMID: 16085226.
      Citations: 24     Fields:    Translation:HumansCells
    121. Ammosova T, Washington K, Debebe Z, Brady J, Nekhai S. Dephosphorylation of CDK9 by protein phosphatase 2A and protein phosphatase-1 in Tat-activated HIV-1 transcription. Retrovirology. 2005 Jul 27; 2:47. PMID: 16048649.
      Citations: 32     Fields:    Translation:HumansAnimalsCells
    122. Epie N, Ammosova T, Sapir T, Voloshin Y, Lane WS, Turner W, Reiner O, Nekhai S. HIV-1 Tat interacts with LIS1 protein. Retrovirology. 2005 Feb 07; 2:6. PMID: 15698475.
      Citations: 17     Fields:    Translation:HumansCells
    123. Ammosova T, Jerebtsova M, Beullens M, Voloshin Y, Ray PE, Kumar A, Bollen M, Nekhai S. Nuclear protein phosphatase-1 regulates HIV-1 transcription. J Biol Chem. 2003 Aug 22; 278(34):32189-94. PMID: 12788939.
      Citations: 29     Fields:    Translation:HumansCells
    124. Washington K, Ammosova T, Beullens M, Jerebtsova M, Kumar A, Bollen M, Nekhai S. Protein phosphatase-1 dephosphorylates the C-terminal domain of RNA polymerase-II. J Biol Chem. 2002 Oct 25; 277(43):40442-8. PMID: 12185079.
      Citations: 31     Fields:    Translation:HumansAnimalsCells
    125. Deng L, Ammosova T, Pumfery A, Kashanchi F, Nekhai S. HIV-1 Tat interaction with RNA polymerase II C-terminal domain (CTD) and a dynamic association with CDK2 induce CTD phosphorylation and transcription from HIV-1 promoter. J Biol Chem. 2002 Sep 13; 277(37):33922-9. PMID: 12114499.
      Citations: 39     Fields:    Translation:HumansCells
    126. Nekhai S, Zhou M, Fernandez A, Lane WS, Lamb NJ, Brady J, Kumar A. HIV-1 Tat-associated RNA polymerase C-terminal domain kinase, CDK2, phosphorylates CDK7 and stimulates Tat-mediated transcription. Biochem J. 2002 Jun 15; 364(Pt 3):649-57. PMID: 12049628.
      Citations: 30     Fields:    Translation:HumansCells
    127. Bharucha DC, Zhou M, Nekhai S, Brady JN, Shukla RR, Kumar A. A protein phosphatase from human T cells augments tat transactivation of the human immunodeficiency virus type 1 long-terminal repeat. Virology. 2002 Apr 25; 296(1):6-16. PMID: 12036313.
      Citations: 8     Fields:    Translation:HumansCells
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