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Cecilia M. Shikuma,MD

TitleChair
Faculty RankProfessor
InstitutionUniversity of Hawaii
DepartmentMedicine
AddressJohn A. Burns School of Medicine
University of Hawaii at Manoa
651 Ilalo Street
Honolulu HI 96813
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    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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    PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Mitchell BI, Yazel Eiser IE, Kallianpur KJ, Gangcuangco LM, Chow DC, Ndhlovu LC, Paul R, Shikuma CM. Dynamics of peripheral T cell exhaustion and monocyte subpopulations in neurocognitive impairment and brain atrophy in chronic HIV infection. J Neurovirol. 2024 Jun 29. PMID: 38949728.
      Citations: 1     Fields:    
    2. Marques de Menezes EG, Bowler SA, Shikuma CM, Ndhlovu LC, Norris PJ. Circulating plasma-derived extracellular vesicles expressing bone and kidney markers are associated with neurocognitive impairment in people living with HIV. Front Neurol. 2024; 15:1383227. PMID: 38725641.
      Citations:    
    3. Yoon H, Dean LS, Jiyarom B, Khadka VS, Deng Y, Nerurkar VR, Chow DC, Shikuma CM, Devendra G, Koh Y, Park J. Single-cell RNA sequencing reveals characteristics of myeloid cells in post-acute sequelae of SARS-CoV-2 patients with persistent respiratory symptoms. Front Immunol. 2023; 14:1268510. PMID: 38259488.
      Citations: 2     Fields:    Translation:HumansCells
    4. Zorilla RA, Shikuma CM. A Literature Review on the Adherence to Screening Guidelines for Latent Tuberculosis Infection Among Persons Living With HIV. Hawaii J Health Soc Welf. 2023 12; 82(12):289-295. PMID: 38093759.
      Citations:    Fields:    Translation:Humans
    5. Awamura T, Nakasone ES, Gangcuangco LM, Subia NT, Bali AJ, Chow DC, Shikuma CM, Park J. Platelet and HIV Interactions and Their Contribution to Non-AIDS Comorbidities. Biomolecules. 2023 11 02; 13(11). PMID: 38002289.
      Citations:    Fields:    Translation:HumansCells
    6. Vares-Lum DL, Gangcuangco LMA, Park J, Manzano E, Ortega M, Chow DC, Shikuma C. Plasma galectin-3 is associated with decreased glomerular filtration rate in chronic HIV. HIV Res Clin Pract. 2023 09 20; 24(1):2261753. PMID: 37783570.
      Citations:    Fields:    Translation:Humans
    7. Corley MJ, Pang APS, Shikuma CM, Ndhlovu LC. Cell-type specific impact of metformin on monocyte epigenetic age reversal in virally suppressed older people living with HIV. Aging Cell. 2024 01; 23(1):e13926. PMID: 37675817.
      Citations: 4     Fields:    Translation:HumansCells
    8. Park J, Dean LS, Heckl J, Gangcuangco LM, Pedro TK, Tallquist MD, Seto TB, Shiramizu B, Chow DC, Shikuma CM. Low-density granulocytes display immature cells with enhanced NET formation in people living with HIV. Sci Rep. 2023 08 16; 13(1):13282. PMID: 37587169.
      Citations:    Fields:    Translation:HumansCells
    9. Yoon H, Dean LS, Jiyarom B, Khadka V, Deng Y, Nerurukar VR, Chow DC, Shikuma CM, Devendra G, Koh Y, Park J. Single-cell RNA sequencing reveals characteristics of myeloid cells in pulmonary post-acute sequelae of SARS-CoV-2. bioRxiv. 2023 Aug 02. PMID: 37577518.
      Citations:    
    10. Shikuma CM, Wojna V, De Gruttola V, Siriwardhana C, Souza SA, Rodriguez-Benitez RJ, Turner EH, Kallianpur K, Bolzenius J, Chow D, Matos M, Shiramizu B, Clements DM, Premeaux TA, Ndhlovu LC, Paul R. Impact of antiretroviral therapy intensification with C-C motif chemokine receptor 5 antagonist maraviroc on HIV-associated neurocognitive impairment. AIDS. 2023 11 01; 37(13):1987-1995. PMID: 37418541.
      Citations: 3     Fields:    Translation:Humans
    11. Kroll KW, Woolley G, Terry K, Premeaux TA, Shikuma CM, Corley MJ, Bowler S, Ndhlovu LC, Reeves RK. Multiplex Analysis of Cytokines and Chemokines in Persons Aging With or Without HIV. AIDS Res Hum Retroviruses. 2023 07; 39(7):367-380. PMID: 37097212.
      Citations:    Fields:    Translation:Humans
    12. Giannakopoulos S, Strange DP, Jiyarom B, Abdelaal O, Bradshaw AW, Nerurkar VR, Ward MA, Bakse J, Yap J, Vanapruks S, Boisvert WA, Tallquist MD, Shikuma C, Sadri-Ardekani H, Clapp P, Murphy SV, Verma S. In vitro evidence against productive SARS-CoV-2 infection of human testicular cells: Bystander effects of infection mediate testicular injury. PLoS Pathog. 2023 05; 19(5):e1011409. PMID: 37200377.
      Citations: 5     Fields:    Translation:HumansAnimalsCells
    13. Dean LS, Devendra G, Jiyarom B, Subia N, Tallquist MD, Nerurkar VR, Chang SP, Chow DC, Shikuma CM, Park J. Corrigendum: Phenotypic alteration of low-density granulocytes in people with pulmonary post-acute sequelae of SARS-CoV-2 infection. Front Immunol. 2023; 14:1209624. PMID: 37187732.
      Citations: 1     Fields:    
    14. Park J, Dean LS, Jiyarom B, Gangcuangco LM, Shah P, Awamura T, Ching LL, Nerurkar VR, Chow DC, Igno F, Shikuma CM, Devendra G. Elevated circulating monocytes and monocyte activation in COVID-19 convalescent individuals. Front Immunol. 2023; 14:1151780. PMID: 37077911.
      Citations: 16     Fields:    Translation:HumansCells
    15. Asante I, Lu A, Mitchell BI, Boisvert WA, Shikuma CM, Chow DC, Louie SG. Alterations in Renin-Angiotensin System (RAS) Peptide Levels in Patients with HIV. Metabolites. 2022 Dec 31; 13(1). PMID: 36676986.
      Citations:    
    16. de Menezes EGM, Liu JS, Bowler SA, Giron LB, D'Antoni ML, Shikuma CM, Abdel-Mohsen M, Ndhlovu LC, Norris PJ. Circulating brain-derived extracellular vesicles expressing neuroinflammatory markers are associated with HIV-related neurocognitive impairment. Front Immunol. 2022; 13:1033712. PMID: 36601110.
      Citations: 5     Fields:    Translation:HumansCells
    17. Dean LS, Devendra G, Jiyarom B, Subia N, Tallquist MD, Nerurkar VR, Chang SP, Chow DC, Shikuma CM, Park J. Phenotypic alteration of low-density granulocytes in people with pulmonary post-acute sequalae of SARS-CoV-2 infection. Front Immunol. 2022; 13:1076724. PMID: 36591237.
      Citations: 3     Fields:    Translation:HumansCells
    18. Dean LS, Chow DC, Ndhlovu LC, Boisvert WA, Chang SP, Shikuma CM, Park J. Characterization of Circulating Fibrocytes in People Living with HIV on Stable Antiretroviral Therapy. Immunohorizons. 2022 11 01; 6(11):760-767. PMID: 36445359.
      Citations: 1     Fields:    Translation:Humans
    19. Maison DP, Ching LL, Cleveland SB, Tseng AC, Nakano E, Shikuma CM, Nerurkar VR. Dynamic SARS-CoV-2 emergence algorithm for rationally-designed logical next-generation vaccines. Commun Biol. 2022 10 10; 5(1):1081. PMID: 36217024.
      Citations:    
    20. Kroll KW, Shah SV, Lucar OA, Premeaux TA, Shikuma CM, Corley MJ, Mosher M, Woolley G, Bowler S, Ndhlovu LC, Reeves RK. Mucosal-homing natural killer cells are associated with aging in persons living with HIV. Cell Rep Med. 2022 10 18; 3(10):100773. PMID: 36208628.
      Citations: 5     Fields:    Translation:HumansCells
    21. Giannakopoulos S, Strange DP, Jiyarom B, Abdelaal O, Bradshaw AW, Nerurkar VR, Ward MA, Bakse J, Yap J, Vanapruks S, Boisvert W, Tallquist MD, Shikuma C, Sadri-Ardekani H, Clapp P, Murphy S, Verma S. In vitro evidence against productive SARS-CoV-2 infection of human testicular cells: Bystander effects of infection mediate testicular injury. bioRxiv. 2022 Sep 22. PMID: 36172118.
      Citations:    
    22. Dean LS, SahBandar IN, Shikuma CM. Identification and Implications of HIV-1 CRF01_AE Subtype in Hawai'i. Hawaii J Health Soc Welf. 2022 08; 81(8):215-217. PMID: 35923383.
      Citations:    Fields:    Translation:HumansCells
    23. Ching LL, Tseng AC, Nakano E, Salomon RC, Wang WK, Shikuma C, Nerurkar VR. COVID-19 vaccination and booster induced authentic-virus neutralizing antibody response is superior to SARS-CoV-2 natural infection induced response. J Clin Virol. 2022 07; 152:105185. PMID: 35605371.
      Citations: 3     Fields:    Translation:HumansCellsPHPublic Health
    24. Marques de Menezes EG, Deng X, Liu J, Bowler SA, Shikuma CM, Stone M, Hunt PW, Ndhlovu LC, Norris PJ. Plasma CD16+ Extracellular Vesicles Associate with Carotid Artery Intima-Media Thickness in HIV+ Adults on Combination Antiretroviral Therapy. mBio. 2022 06 28; 13(3):e0300521. PMID: 35435733.
      Citations: 5     Fields:    Translation:HumansCells
    25. Shikuma CM, Le T, Phuong TV, Chew GM, Nguyen VVC, Vo TL, Siriwardhana C, Chow D, Ghukasyan H, Limpruttidham N, Premeaux T, Gangcuangco LM, Paul R, Ndhlovu LC. Immunologic Change over 72 Weeks Following Raltegravir- Versus Efavirenz-Based Therapy in HIV/HCV-Coinfected Individuals in Vietnam. AIDS Res Hum Retroviruses. 2022 06; 38(6):441-450. PMID: 34861767.
      Citations:    Fields:    Translation:HumansCells
    26. Adeniji OS, Kuri-Cervantes L, Yu C, Xu Z, Ho M, Chew GM, Shikuma C, Tomescu C, George AF, Roan NR, Ndhlovu LC, Liu Q, Muthumani K, Weiner DB, Betts MR, Xiao H, Abdel-Mohsen M. Siglec-9 defines and restrains a natural killer subpopulation highly cytotoxic to HIV-infected cells. PLoS Pathog. 2021 11; 17(11):e1010034. PMID: 34762717.
      Citations: 8     Fields:    Translation:HumansCells
    27. Kiefer EM, Ross KS, Santos AC, Barney MR, McCormick TJ, Chow DC, Shikuma CM. Incident Cases of Sexually Transmitted Infections among Users of Pre-Exposure Prophylaxis for HIV Prevention in Honolulu, Hawai'i. Hawaii J Health Soc Welf. 2021 07; 80(7):148-154. PMID: 34278321.
      Citations:    Fields:    Translation:HumansPHPublic Health
    28. Gangcuangco LMA, Mitchell BI, Siriwardhana C, Kohorn LB, Chew GM, Bowler S, Kallianpur KJ, Chow DC, Ndhlovu LC, Gerschenson M, Shikuma CM. Correction: Mitochondrial oxidative phosphorylation in peripheral blood mononuclear cells is decreased in chronic HIV and correlates with immune dysregulation. PLoS One. 2021; 16(3):e0249428. PMID: 33765089.
      Citations: 1     Fields:    
    29. Paul RH, Shikuma CM, Chau NVV, Ndhlovu LC, Thanh NT, Belden AC, Chow DC, Chew GM, Premeaux TA, Ly VT, McBride JAD, Bolzenius JD, Le T. Neurocognitive Trajectories After 72 Weeks of First-Line Anti-retroviral Therapy in Vietnamese Adults With HIV-HCV Co-infection. Front Neurol. 2021; 12:602263. PMID: 33776879.
      Citations:    
    30. Bowler S, Mitchell BI, Kallianpur KJ, Chow D, Jiang W, Shikuma CM, Ndhlovu LC. Plasma anti-CD4 IgG is associated with brain abnormalities in people with HIV on antiretroviral therapy. J Neurovirol. 2021 04; 27(2):334-339. PMID: 33710596.
      Citations: 3     Fields:    Translation:HumansCells
    31. Hedges JR, Soliman KFA, Southerland WM, D'Amour G, Fern?ndez-Repollet E, Khan SA, Kumar D, Shikuma CM, Rivers BM, Yates CC, Yanagihara R, Thompson WE, Bond VC, Harris-Hooker S, McClure SA, Ofili EO. Strengthening and Sustaining Inter-Institutional Research Collaborations and Partnerships. Int J Environ Res Public Health. 2021 03 08; 18(5). PMID: 33800316.
      Citations: 3     Fields:    Translation:Humans
    32. Maison DP, Ching LL, Shikuma CM, Nerurkar VR. Genetic Characteristics and Phylogeny of 969-bp S Gene Sequence of SARS-CoV-2 from Hawai'i Reveals the Worldwide Emerging P681H Mutation. Hawaii J Health Soc Welf. 2021 03 01; 80(3):52-61. PMID: 33718878.
      Citations: 28     Fields:    Translation:HumansCells
    33. Maison DP, Ching LL, Shikuma CM, Nerurkar VR. Genetic Characteristics and Phylogeny of 969-bp S Gene Sequence of SARS-CoV-2 from Hawaii Reveals the Worldwide Emerging P681H Mutation. bioRxiv. 2021 Jan 07. PMID: 33442699.
      Citations:    
    34. Nir TM, Fouche JP, Ananworanich J, Ances BM, Boban J, Brew BJ, Chaganti JR, Chang L, Ching CRK, Cysique LA, Ernst T, Faskowitz J, Gupta V, Harezlak J, Heaps-Woodruff JM, Hinkin CH, Hoare J, Joska JA, Kallianpur KJ, Kuhn T, Lam HY, Law M, Lebrun-Fr?nay C, Levine AJ, Mondot L, Nakamoto BK, Navia BA, Pennec X, Porges EC, Salminen LE, Shikuma CM, Surento W, Thames AD, Valcour V, Vassallo M, Woods AJ, Thompson PM, Cohen RA, Paul R, Stein DJ, Jahanshad N. Association of Immunosuppression and Viral Load With Subcortical Brain Volume in an International Sample of People Living With HIV. JAMA Netw Open. 2021 01 04; 4(1):e2031190. PMID: 33449093.
      Citations: 11     Fields:    Translation:Humans
    35. McClean M, Buzkova P, Budoff M, Estrella M, Freiberg M, Hodis HN, Palella F, Shikuma C, Post WS, Gupta S. Brief Report: Cystatin C-Based Estimation of Glomerular Filtration Rate and Association With Atherosclerosis Imaging Markers in People Living With HIV. J Acquir Immune Defic Syndr. 2020 12 01; 85(4):466-469. PMID: 33136746.
      Citations: 2     Fields:    Translation:HumansCells
    36. Baumer Y, Weatherby TM, Mitchell BI, SahBandar IN, Premeaux TA, Michelle L D, Gutierrez-Huerta CA, Powell-Wiley TM, Brown TR, Boisvert WA, Shikuma CM, Ndhlovu LC. Hiding in plain sight - platelets, the silent carriers of HIV-1. Platelets. 2021 Nov 17; 32(8):1038-1042. PMID: 33222575.
      Citations: 2     Fields:    Translation:HumansCells
    37. Chew GM, Padua AJP, Chow DC, Souza SA, Clements DM, Corley MJ, Pang APS, Alejandria MM, Gerschenson M, Shikuma CM, Ndhlovu LC. Effects of Brief Adjunctive Metformin Therapy in Virologically Suppressed HIV-Infected Adults on Polyfunctional HIV-Specific CD8 T Cell Responses to PD-L1 Blockade. AIDS Res Hum Retroviruses. 2021 01; 37(1):24-33. PMID: 33019813.
      Citations: 6     Fields:    Translation:HumansCellsCTClinical Trials
    38. Mitchell BI, Laws EI, Chow DC, SahBandar IN, Gangcuangco LMA, Shikuma CM, Ndhlovu LC. Increased Monocyte Inflammatory Responses to Oxidized LDL Are Associated with Insulin Resistance in HIV-Infected Individuals on Suppressive Antiretroviral Therapy. Viruses. 2020 10 05; 12(10). PMID: 33028018.
      Citations: 1     Fields:    Translation:HumansCells
    39. Chow DC, Mau M, Hodis HN, Kewcharoen J, Li Y, Siriwardhana C, Souza SA, Mitchell BI, Bowler S, SahBandar I, Gangcuangco LMA, MacPherson I, Ndhlovu LC, Shikuma CM. Short Communication: Carotid Artery Plaque Burden in HIV Is Associated with Soluble Mediators and Monocytes. AIDS Res Hum Retroviruses. 2020 12; 36(12):1020-1023. PMID: 32862657.
      Citations: 2     Fields:    Translation:HumansCells
    40. Kallianpur KJ, Birn R, Ndhlovu LC, Souza SA, Mitchell B, Paul R, Chow DC, Kohorn L, Shikuma CM. Impact of Cannabis Use on Brain Structure and Function in Suppressed HIV Infection. J Behav Brain Sci. 2020 Aug; 10(8):344-370. PMID: 32968547.
      Citations:    
    41. Chow DC, Bernas MA, Gangcuangco LM, Huynh J, Kohorn LB, Kallianpur KJ, Souza SA, Shiramizu B, Ndhlovu LC, Shikuma CM. Frailty Is Associated With Insulin Resistance in Chronic Human Immunodeficiency Virus Infection. Clin Infect Dis. 2020 08 14; 71(4):1127-1128. PMID: 31612202.
      Citations: 1     Fields:    Translation:HumansCells
    42. SahBandar IN, Chew GM, Corley MJ, Pang APS, Tsai N, Hanks N, Khadka VS, Klatt NR, Hensley-McBain T, Somsouk M, Vujkovic-Cvijin I, Chow DC, Shikuma CM, Ndhlovu LC. Changes in gastrointestinal microbial communities influence HIV-specific CD8+ T-cell responsiveness to immune checkpoint blockade. AIDS. 2020 08 01; 34(10):1451-1460. PMID: 32675558.
      Citations: 3     Fields:    Translation:HumansCells
    43. Gangcuangco LMA, Mitchell BI, Siriwardhana C, Kohorn LB, Chew GM, Bowler S, Kallianpur KJ, Chow DC, Ndhlovu LC, Gerschenson M, Shikuma CM. Mitochondrial oxidative phosphorylation in peripheral blood mononuclear cells is decreased in chronic HIV and correlates with immune dysregulation. PLoS One. 2020; 15(4):e0231761. PMID: 32353005.
      Citations: 14     Fields:    Translation:HumansCells
    44. Shikuma CM, Chew GM, Kohorn L, Souza SA, Chow D, SahBandar IN, Park EY, Hanks N, Gangcuangco LMA, Gerschenson M, Ndhlovu LC. Short Communication: Metformin Reduces CD4 T Cell Exhaustion in HIV-Infected Adults on Suppressive Antiretroviral Therapy. AIDS Res Hum Retroviruses. 2020 04; 36(4):303-305. PMID: 31731885.
      Citations: 19     Fields:    Translation:HumansCells
    45. D'Antoni ML, Kallianpur KJ, Premeaux TA, Corley MJ, Fujita T, Laws EI, Ogata-Arakaki D, Chow DC, Khadka VS, Shikuma CM, Ndhlovu LC. Lower Interferon Regulatory Factor-8 Expression in Peripheral Myeloid Cells Tracks With Adverse Central Nervous System Outcomes in Treated HIV Infection. Front Immunol. 2019; 10:2789. PMID: 31849969.
      Citations: 1     Fields:    Translation:HumansCells
    46. Kallianpur KJ, Walker M, Gerschenson M, Shikuma CM, Gangcuangco LMA, Kohorn L, Libutti DE, Nir TM, Jahanshad N, Thompson PM, Paul R. Systemic Mitochondrial Oxidative Phosphorylation Protein Levels Correlate with Neuroimaging Measures in Chronically HIV-Infected Individuals. AIDS Res Hum Retroviruses. 2020 01; 36(1):83-91. PMID: 31617381.
      Citations: 6     Fields:    Translation:HumansCells
    47. SahBandar IN, Ndhlovu LC, Saiki K, Kohorn LB, Peterson MM, D'Antoni ML, Shiramizu B, Shikuma CM, Chow DC. Relationship between Circulating Inflammatory Monocytes and Cardiovascular Disease Measures of Carotid Intimal Thickness. J Atheroscler Thromb. 2020 May 01; 27(5):441-448. PMID: 31588100.
      Citations: 22     Fields:    Translation:HumansCells
    48. Gojanovich GS, Shikuma CM, Milne C, Libutti DE, Chow DC, Gerschenson M. Subcutaneous Adipocyte Adenosine Triphosphate Levels in HIV Infected Patients. AIDS Res Hum Retroviruses. 2020 01; 36(1):75-82. PMID: 31407586.
      Citations: 3     Fields:    Translation:HumansCells
    49. Limpruttidham N, Mitchell BI, Kallianpur KJ, Nakamoto BK, Souza SA, Shiramizu B, Ndhlovu LC, Chow DC, Shikuma CM. S100B and its association with HIV-associated neurocognitive disorders. J Neurovirol. 2019 12; 25(6):899-900. PMID: 31278533.
      Citations: 2     Fields:    Translation:Humans
    50. Dye CK, Corley MJ, Li D, Khadka VS, Mitchell BI, Sultana R, Lum-Jones A, Shikuma CM, Ndhlovu LC, Maunakea AK. Comparative DNA methylomic analyses reveal potential origins of novel epigenetic biomarkers of insulin resistance in monocytes from virally suppressed HIV-infected adults. Clin Epigenetics. 2019 06 28; 11(1):95. PMID: 31253200.
      Citations: 9     Fields:    Translation:HumansCells
    51. Bowler S, Chew GM, Budoff M, Chow D, Mitchell BI, D'Antoni ML, Siriwardhana C, Ndhlovu LC, Shikuma C. PD-1+ and TIGIT+ CD4 T Cells Are Associated With Coronary Artery Calcium Progression in HIV-Infected Treated Adults. J Acquir Immune Defic Syndr. 2019 05 01; 81(1):e21-e23. PMID: 30865177.
      Citations: 3     Fields:    Translation:HumansCells
    52. Le Ngoc C, Tran Thi Thanh T, Tran Thi Lan P, Nguyen Mai T, Nguyen Hoa T, Nghiem My N, Le Van T, Le Manh H, Le Thanh P, Nguyen Van Vinh C, Thwaites G, Cooke G, Heilek GM, Shikuma C, Le T, Baker S, Rahman M. Differential prevalence and geographic distribution of hepatitis C virus genotypes in acute and chronic hepatitis C patients in Vietnam. PLoS One. 2019; 14(3):e0212734. PMID: 30865664.
      Citations: 11     Fields:    Translation:HumansCellsCTClinical Trials
    53. Premeaux TA, D'Antoni ML, Abdel-Mohsen M, Pillai SK, Kallianpur KJ, Nakamoto BK, Agsalda-Garcia M, Shiramizu B, Shikuma CM, Gissl?n M, Price RW, Valcour V, Ndhlovu LC. Elevated cerebrospinal fluid Galectin-9 is associated with central nervous system immune activation and poor cognitive performance in older HIV-infected individuals. J Neurovirol. 2019 04; 25(2):150-161. PMID: 30478799.
      Citations: 17     Fields:    Translation:HumansCells
    54. Shikuma CM, Kohorn L, Paul R, Chow DC, Kallianpur KJ, Walker M, Souza S, Gangcuangco LMA, Nakamoto BK, Pien FD, Duerler T, Castro L, Nagamine L, Soll B. Sleep and neuropsychological performance in HIV+ subjects on efavirenz-based therapy and response to switch in therapy. HIV Clin Trials. 2018 08; 19(4):139-147. PMID: 30451595.
      Citations: 14     Fields:    Translation:HumansCells
    55. Zhang Z, Chew GM, Shikuma CM, Gangcuangco LMA, Souza SA, Shiramizu B, Nakamoto BK, Gong T, Mannem SR, Mitchell BI, Kallianpur KJ, Ndhlovu LC, Chow DC. Red blood cell distribution width as an easily measurable biomarker of persistent inflammation and T cell dysregulation in antiretrovirally treated HIV-infected adults. HIV Clin Trials. 2018 10; 19(5):172-176. PMID: 30422099.
      Citations: 7     Fields:    Translation:HumansCells
    56. D'Antoni ML, Paul RH, Mitchell BI, Kohorn L, Fischer L, Lefebvre E, Seyedkazemi S, Nakamoto BK, Walker M, Kallianpur KJ, Ogata-Arakaki D, Ndhlovu LC, Shikuma C. Improved Cognitive Performance and Reduced Monocyte Activation in Virally Suppressed Chronic HIV After Dual CCR2 and CCR5 Antagonism. J Acquir Immune Defic Syndr. 2018 09 01; 79(1):108-116. PMID: 29781885.
      Citations: 33     Fields:    Translation:HumansCellsCTClinical Trials
    57. D'Antoni ML, Mitchell BI, McCurdy S, Byron MM, Ogata-Arakaki D, Chow D, Mehta NN, Boisvert WA, Lefebvre E, Shikuma CM, Ndhlovu LC, Baumer Y. Cenicriviroc inhibits trans-endothelial passage of monocytes and is associated with impaired E-selectin expression. J Leukoc Biol. 2018 12; 104(6):1241-1252. PMID: 30088682.
      Citations: 11     Fields:    Translation:HumansCells
    58. McIntosh RC, Paul R, Ndhlovu LC, Hidalgo M, Lobo JD, Walker M, Shikuma CM, Kallianpur KJ. Resting-state connectivity and spontaneous activity of ventromedial prefrontal cortex predict depressive symptomology and peripheral inflammation in HIV. J Neurovirol. 2018 10; 24(5):616-628. PMID: 30022427.
      Citations: 12     Fields:    Translation:Humans
    59. McIntosh RC, Chow DC, Lum CJ, Shikuma CM, Kallianpur KJ. Reply to "The insular cortex and QTc interval in HIV+ and HIV- individuals: Is there an effect of sympathetic nervous system activity?" Clin Neurophysiol. 2018 01; 129(1):337-338. PMID: 29169688.
      Citations:    Fields:    Translation:Humans
    60. McIntosh RC, Chow DC, Lum CJ, Hidalgo M, Shikuma CM, Kallianpur KJ. Reduced functional connectivity between ventromedial prefrontal cortex and insula relates to longer corrected QT interval in HIV+ and HIV- individuals. Clin Neurophysiol. 2017 10; 128(10):1839-1850. PMID: 28826014.
      Citations: 6     Fields:    Translation:Humans
    61. SahBandar IN, Samonte G, Telan E, Siripong N, Belcaid M, Schanzenbach D, Leano S, Chagan-Yasutan H, Hattori T, Shikuma CM, Ndhlovu LC. Ultra-Deep Sequencing Analysis on HIV Drug-Resistance-Associated Mutations Among HIV-Infected Individuals: First Report from the Philippines. AIDS Res Hum Retroviruses. 2017 Nov; 33(11):1099-1106. PMID: 28569550.
      Citations: 6     Fields:    Translation:HumansCells
    62. Kocher M, McDermott M, Lindsey R, Shikuma CM, Gerschenson M, Chow DC, Kohorn LB, Hetzler RK, Kimura IF. Short Communication: HIV Patient Systemic Mitochondrial Respiration Improves with Exercise. AIDS Res Hum Retroviruses. 2017 Oct; 33(10):1035-1037. PMID: 28467726.
      Citations: 4     Fields:    Translation:HumansCells
    63. Le T, Kinh NV, Cuc NTK, Tung NLN, Lam NT, Thuy PTT, Cuong DD, Phuc PTH, Vinh VH, Hanh DTH, Tam VV, Thanh NT, Thuy TP, Hang NT, Long HB, Nhan HT, Wertheim HFL, Merson L, Shikuma C, Day JN, Chau NVV, Farrar J, Thwaites G, Wolbers M. A Trial of Itraconazole or Amphotericin B for HIV-Associated Talaromycosis. N Engl J Med. 2017 06 15; 376(24):2329-2340. PMID: 28614691.
      Citations: 70     Fields:    Translation:HumansAnimals
    64. Wirunsawanya K, Belyea L, Shikuma C, Watanabe RM, Kohorn L, Shiramizu B, Mitchell BI, Souza SA, Keating SM, Norris PJ, Ndhlovu LC, Chow D. Plasminogen Activator Inhibitor-1 Predicts Negative Alterations in Whole-Body Insulin Sensitivity in Chronic HIV Infection. AIDS Res Hum Retroviruses. 2017 07; 33(7):723-727. PMID: 28322572.
      Citations: 6     Fields:    Translation:Humans
    65. Thanh NT, Vinh LD, Liem NT, Shikuma C, Day JN, Thwaites G, Le T. Clinical features of three patients with paradoxical immune reconstitution inflammatory syndrome associated with Talaromyces marneffei infection. Med Mycol Case Rep. 2018 Mar; 19:33-37. PMID: 29379703.
      Citations:    
    66. Gangcuangco LMA, Kohorn LB, Chow DC, Keating SM, Norris PJ, Nagamine LS, Ndhlovu LC, Souza SA, Kallianpur KJ, Shikuma CM. High 25-hydroxyvitamin D is associated with unexpectedly high plasma inflammatory markers in HIV patients on antiretroviral therapy. Medicine (Baltimore). 2016 Oct; 95(43):e5270. PMID: 27787390.
      Citations: 2     Fields:    Translation:Humans
    67. Chow D, Shikuma C, Ritchings C, Guo M, Rosenblatt L. Atazanavir and Cardiovascular Risk Among Human Immunodeficiency Virus-Infected Patients: A Systematic Review. Infect Dis Ther. 2016 Dec; 5(4):473-489. PMID: 27677263.
      Citations:    
    68. Corley MJ, Dye C, D'Antoni ML, Byron MM, Yo KL, Lum-Jones A, Nakamoto B, Valcour V, SahBandar I, Shikuma CM, Ndhlovu LC, Maunakea AK. Comparative DNA Methylation Profiling Reveals an Immunoepigenetic Signature of HIV-related Cognitive Impairment. Sci Rep. 2016 09 15; 6:33310. PMID: 27629381.
      Citations: 28     Fields:    Translation:HumansCells
    69. Kallianpur KJ, Sakoda M, Gangcuangco LM, Ndhlovu LC, Umaki T, Chow D, Wongjittraporn S, Shikuma CM. Frailty Characteristics in Chronic HIV Patients are Markers of White Matter Atrophy Independently of Age and Depressive Symptoms: A Pilot Study. Open Med J. 2016; 3:138-152. PMID: 27721908.
      Citations:    
    70. Abdel-Mohsen M, Chavez L, Tandon R, Chew GM, Deng X, Danesh A, Keating S, Lanteri M, Samuels ML, Hoh R, Sacha JB, Norris PJ, Niki T, Shikuma CM, Hirashima M, Deeks SG, Ndhlovu LC, Pillai SK. Human Galectin-9 Is a Potent Mediator of HIV Transcription and Reactivation. PLoS Pathog. 2016 06; 12(6):e1005677. PMID: 27253379.
      Citations: 43     Fields:    Translation:HumansCells
    71. Riangwiwat T, Kohorn LB, Chow DC, Souza SA, Ndhlovu LC, Wong JW, Gangcuangco LM, Shikuma CM. CD4/CD8 Ratio Predicts Peripheral Fat in HIV-Infected Population. J Acquir Immune Defic Syndr. 2016 May 01; 72(1):e17-9. PMID: 26885805.
      Citations: 2     Fields:    Translation:HumansCells
    72. Hanna DB, Guo M, Bu?kov? P, Miller TL, Post WS, Stein JH, Currier JS, Kronmal RA, Freiberg MS, Bennett SN, Shikuma CM, Anastos K, Li Y, Tracy RP, Hodis HN, Delaney JA, Kaplan RC. HIV Infection and Carotid Artery Intima-media Thickness: Pooled Analyses Across 5 Cohorts of the NHLBI HIV-CVD Collaborative. Clin Infect Dis. 2016 07 15; 63(2):249-56. PMID: 27118787.
      Citations: 35     Fields:    Translation:Humans
    73. Mitchell BI, Byron MM, Ng RC, Chow DC, Ndhlovu LC, Shikuma CM. Elevation of Non-Classical (CD14+/lowCD16++) Monocytes Is Associated with Increased Albuminuria and Urine TGF-?1 in HIV-Infected Individuals on Stable Antiretroviral Therapy. PLoS One. 2016; 11(4):e0153758. PMID: 27097224.
      Citations: 4     Fields:    Translation:HumansCells
    74. Chow DC, Kagihara JM, Zhang G, Souza SA, Hodis HN, Li Y, Mitchell BI, Nakamoto BK, Kallianpur KJ, Keating SM, Norris PJ, Kohorn LB, Ndhlovu LC, Shikuma CM. Non-classical monocytes predict progression of carotid artery bifurcation intima-media thickness in HIV-infected individuals on stable antiretroviral therapy. HIV Clin Trials. 2016 05; 17(3):114-22. PMID: 27125366.
      Citations: 19     Fields:    Translation:HumansCells
    75. Kallianpur KJ, Gerschenson M, Mitchell BI, LiButti DE, Umaki TM, Ndhlovu LC, Nakamoto BK, Chow DC, Shikuma CM. Oxidative mitochondrial DNA damage in peripheral blood mononuclear cells is associated with reduced volumes of hippocampus and subcortical gray matter in chronically HIV-infected patients. Mitochondrion. 2016 05; 28:8-15. PMID: 26923169.
      Citations: 24     Fields:    Translation:HumansCells
    76. Chow D, Kohorn L, Souza S, Ndhlovu L, Ando A, Kallianpur KJ, Byron MM, Baumer Y, Keating S, Shikuma C. Atazanavir use and carotid intima media thickness progression in HIV: potential influence of bilirubin. AIDS. 2016 Feb 20; 30(4):672-4. PMID: 26825035.
      Citations: 6     Fields:    Translation:Humans
    77. Zungsontiporn N, Tello RR, Zhang G, Mitchell BI, Budoff M, Kallianpur KJ, Nakamoto BK, Keating SM, Norris PJ, Ndhlovu LC, Souza SA, Shikuma CM, Chow DC. Non-Classical Monocytes and Monocyte Chemoattractant Protein-1 (MCP-1) Correlate with Coronary Artery Calcium Progression in Chronically HIV-1 Infected Adults on Stable Antiretroviral Therapy. PLoS One. 2016; 11(2):e0149143. PMID: 26867220.
      Citations: 24     Fields:    Translation:HumansCells
    78. Chew GM, Fujita T, Webb GM, Burwitz BJ, Wu HL, Reed JS, Hammond KB, Clayton KL, Ishii N, Abdel-Mohsen M, Liegler T, Mitchell BI, Hecht FM, Ostrowski M, Shikuma CM, Hansen SG, Maurer M, Korman AJ, Deeks SG, Sacha JB, Ndhlovu LC. TIGIT Marks Exhausted T Cells, Correlates with Disease Progression, and Serves as a Target for Immune Restoration in HIV and SIV Infection. PLoS Pathog. 2016 Jan; 12(1):e1005349. PMID: 26741490.
      Citations: 178     Fields:    Translation:HumansAnimalsCells
    79. Thao VP, Quang VM, Day JN, Chinh NT, Shikuma CM, Farrar J, Van Vinh Chau N, Thwaites GE, Dunstan SJ, Le T. High prevalence of PI resistance in patients failing second-line ART in Vietnam. J Antimicrob Chemother. 2016 Mar; 71(3):762-74. PMID: 26661398.
      Citations: 11     Fields:    Translation:HumansCells
    80. Zungsontiporn N, Ndhlovu LC, Mitchell BI, Stein JH, Kallianpur KJ, Nakamoto B, Keating SM, Norris PJ, Souza SA, Shikuma CM, Chow DC. Serum amyloid P (SAP) is associated with impaired brachial artery flow-mediated dilation in chronically HIV-1 infected adults on stable antiretroviral therapy. HIV Clin Trials. 2015 11; 16(6):228-35. PMID: 26777795.
      Citations: 4     Fields:    Translation:HumansCells
    81. Thao VP, Quang VM, Wolbers M, Anh ND, Shikuma C, Farrar J, Dunstan S, Chau NVV, Day J, Thwaites G, Le T. Second-Line HIV Therapy Outcomes and Determinants of Mortality at the Largest HIV Referral Center in Southern Vietnam. Medicine (Baltimore). 2015 Oct; 94(43):e1715. PMID: 26512561.
      Citations: 17     Fields:    Translation:Humans
    82. Ndhlovu LC, D'Antoni ML, Ananworanich J, Byron MM, Chalermchai T, Sithinamsuwan P, Tipsuk S, Ho E, Slike BM, Schuetz A, Zhang G, Agsalda-Garcia M, Shiramizu B, Shikuma CM, Valcour V. Loss of CCR2 expressing non-classical monocytes are associated with cognitive impairment in antiretroviral therapy-na?ve HIV-infected Thais. J Neuroimmunol. 2015 Nov 15; 288:25-33. PMID: 26531691.
      Citations: 17     Fields:    Translation:HumansCells
    83. Chang DA, Ede RC, Chow DC, Souza RD, Gangcuangco LM, Hanks N, Nakamoto BK, Mitchell B, Masutani AT, Fisk S, Shikuma CM, Dill JE. Early Childhood Vision Screening in Hawai'i Utilizing a Hand-Held Screener. Hawaii J Med Public Health. 2015 Sep; 74(9):292-6. PMID: 26468424.
      Citations: 5     Fields:    Translation:HumansPHPublic Health
    84. Chow D, Nakamoto BK, Sullivan K, Sletten DM, Fujii S, Umekawa S, Kocher M, Kallianpur KJ, Shikuma CM, Low P. Symptoms of Autonomic Dysfunction in Human Immunodeficiency Virus. Open Forum Infect Dis. 2015 Sep; 2(3):ofv103. PMID: 26269797.
      Citations:    
    85. Chow D, Young R, Valcour N, Kronmal RA, Lum CJ, Parikh NI, Tracy RP, Budoff M, Shikuma CM. HIV and coronary artery calcium score: comparison of the Hawaii Aging with HIV Cardiovascular Study and Multi-Ethnic Study of Atherosclerosis (MESA) cohorts. HIV Clin Trials. 2015 08; 16(4):130-8. PMID: 26038953.
      Citations: 12     Fields:    Translation:HumansCTClinical Trials
    86. Kocher MH, Hetzler RK, Shikuma CM, Kimura IF, Stickley CD, Lindsey RA, Nakamoto BK, Chow DC. Autonomic Function is Associated with Fitness Level in HIV-Infected Individuals. Jacobs J AIDS HIV. 2015 Jun; 1(1). PMID: 26213714.
      Citations:    
    87. Shikuma CM, Bennett K, Ananworanich J, Gerschenson M, Teeratakulpisarn N, Jadwattanakul T, DeGruttola V, McArthur JC, Ebenezer G, Chomchey N, Praihirunkit P, Hongchookiat P, Mathajittiphun P, Nakamoto B, Hauer P, Phanuphak P, Phanuphak N. Distal leg epidermal nerve fiber density as a surrogate marker of HIV-associated sensory neuropathy risk: risk factors and change following initial antiretroviral therapy. J Neurovirol. 2015 Oct; 21(5):525-34. PMID: 26002840.
      Citations: 4     Fields:    Translation:HumansCells
    88. Krishnan S, Schouten JT, Atkinson B, Brown TT, Wohl DA, McComsey GA, Glesby MJ, Shikuma C, Haubrich R, Jacobson DL. Changes in metabolic syndrome status after initiation of antiretroviral therapy. J Acquir Immune Defic Syndr. 2015 Jan 01; 68(1):73-80. PMID: 25321179.
      Citations: 13     Fields:    Translation:Humans
    89. Munger AM, Chow DC, Playford MP, Parikh NI, Gangcuangco LM, Nakamoto BK, Kallianpur KJ, Ndhlovu LC, Shikuma CM, Mehta NN. Characterization of lipid composition and high-density lipoprotein function in HIV-infected individuals on stable antiretroviral regimens. AIDS Res Hum Retroviruses. 2015 Feb; 31(2):221-8. PMID: 25416403.
      Citations: 10     Fields:    Translation:Humans
    90. Sentell TL, Valcour N, Ahn HJ, Miyamura J, Nakamoto B, Chow D, Masaki K, Seto TB, Chen JJ, Shikuma C. High rates of Native Hawaiian and older Japanese adults hospitalized with dementia in Hawai'i. J Am Geriatr Soc. 2015 Jan; 63(1):158-64. PMID: 25537987.
      Citations: 9     Fields:    Translation:Humans
    91. Parikh NI, Gerschenson M, Bennett K, Gangcuangco LM, Lopez MS, Mehta NN, Playford MP, Nakamoto BK, Seto TB, Chow DC, Shikuma CM. Lipoprotein concentration, particle number, size and cholesterol efflux capacity are associated with mitochondrial oxidative stress and function in an HIV positive cohort. Atherosclerosis. 2015 Mar; 239(1):50-4. PMID: 25574857.
      Citations: 12     Fields:    Translation:HumansCells
    92. O-charoen P, Ndhlovu LC, Gangcuangco LM, Keating SM, Norris PJ, Ng RC, Mitchell BI, Shikuma CM, Chow DC. Albuminuria is associated with elevated acute phase reactants and proinflammatory markers in HIV-infected patients receiving suppressive combination antiretroviral therapy. AIDS Res Hum Retroviruses. 2014 Dec; 30(12):1185-91. PMID: 25205472.
      Citations: 3     Fields:    Translation:Humans
    93. Sentell T, Marten L, Ahn HJ, Qui Y, Chen JJ, Miyamura J, Chow D, Shikuma C. Disparities in hospitalizations among HIV positive individuals for Native Hawaiians and Asians compared to Whites in Hawai'i. Hawaii J Med Public Health. 2014 Oct; 73(10):308-14. PMID: 25337448.
      Citations: 3     Fields:    Translation:Humans
    94. Ndhlovu LC, Umaki T, Chew GM, Chow DC, Agsalda M, Kallianpur KJ, Paul R, Zhang G, Ho E, Hanks N, Nakamoto B, Shiramizu BT, Shikuma CM. Treatment intensification with maraviroc (CCR5 antagonist) leads to declines in CD16-expressing monocytes in cART-suppressed chronic HIV-infected subjects and is associated with improvements in neurocognitive test performance: implications for HIV-associated neurocognitive disease (HAND). J Neurovirol. 2014 Dec; 20(6):571-82. PMID: 25227930.
      Citations: 57     Fields:    Translation:HumansCells
    95. Kallianpur KJ, Valcour VG, Lerdlum S, Busovaca E, Agsalda M, Sithinamsuwan P, Chalermchai T, Fletcher JL, Tipsuk S, Shikuma CM, Shiramizu BT, Ananworanich J. HIV DNA in CD14+ reservoirs is associated with regional brain atrophy in patients naive to combination antiretroviral therapy. AIDS. 2014 Jul 17; 28(11):1619-24. PMID: 25232899.
      Citations: 15     Fields:    Translation:HumansCells
    96. Hulgan T, Levinson RT, Gerschenson M, Phanuphak N, Ananworanich J, Teeratakulpisarm N, Jadwattanakul T, LiButti DE, Fink H, McArthur JC, Ebenezer GJ, Hauer P, Murdock D, Shikuma CM, Samuels DC. Epidermal nerve fiber density, oxidative stress, and mitochondrial haplogroups in HIV-infected Thais initiating therapy. AIDS. 2014 Jul 17; 28(11):1625-33. PMID: 24785954.
      Citations: 3     Fields:    Translation:HumansAnimalsCells
    97. Sullivan K, Shikuma CM, Chow D, Cornelius E, Romine RK, Lindsey RA, Stickley CD, Kimura IF, Hetzler RK. Aerobic fitness levels and validation of a non exercise VO2max prediction equation for HIV-infected patients on HAART. HIV Clin Trials. 2014 Mar-Apr; 15(2):69-77. PMID: 24710921.
      Citations: 1     Fields:    Translation:HumansCells
    98. Shikuma CM, Chow DC, Gangcuangco LM, Zhang G, Keating SM, Norris PJ, Seto TB, Parikh N, Kallianpur KJ, Nakamoto BK, Nagamine LS, Ndhlovu LC, Barbour JD. Monocytes expand with immune dysregulation and is associated with insulin resistance in older individuals with chronic HIV. PLoS One. 2014; 9(2):e90330. PMID: 24587328.
      Citations: 27     Fields:    Translation:HumansCells
    99. Shikuma CM, Gangcuangco LM, Killebrew DA, Libutti DE, Chow DC, Nakamoto BK, Liang CY, Milne CI, Ndhlovu LC, Barbour JD, Shiramizu BT, Gerschenson M. The role of HIV and monocytes/macrophages in adipose tissue biology. J Acquir Immune Defic Syndr. 2014 Feb 01; 65(2):151-9. PMID: 24091690.
      Citations: 29     Fields:    Translation:HumansCells
    100. Umaki TM, Gangcuangco LM, Chow DC, Nakamoto BK, Marotz L, Kallianpur KJ, Shikuma CM. Poorer neuropsychological performance increases risk for social services among HIV-infected individuals. Hawaii J Med Public Health. 2013 Dec; 72(12):422-6. PMID: 24377076.
      Citations: 3     Fields:    Translation:Humans
    101. Barbour JD, Jalbert EC, Chow DC, Gangcuangco LM, Norris PJ, Keating SM, Heitman J, Nagamine L, Seto T, Ndhlovu LC, Nakamoto BK, Hodis HN, Parikh NI, Shikuma CM. Reduced CD14 expression on classical monocytes and vascular endothelial adhesion markers independently associate with carotid artery intima media thickness in chronically HIV-1 infected adults on virologically suppressive anti-retroviral therapy. Atherosclerosis. 2014 Jan; 232(1):52-8. PMID: 24401216.
      Citations: 24     Fields:    Translation:HumansCells
    102. Nakamoto BK, Shikuma CM, Ogata-Arakaki D, Umaki T, Neuwelt EA, Shiramizu BT, Chow DC, Parikh NI, Kallianpur KJ, Hamilton BE. Feasibility and potential role of ferumoxytol-enhanced neuroimaging in HIV-associated neurocognitive disorder. J Neurovirol. 2013 Dec; 19(6):601-5. PMID: 24129909.
      Citations: 3     Fields:    Translation:HumansCells
    103. Jalbert E, Crawford TQ, D'Antoni ML, Keating SM, Norris PJ, Nakamoto BK, Seto T, Parikh NI, Shikuma CM, Ndhlovu LC, Barbour JD. IL-1? enriched monocytes mount massive IL-6 responses to common inflammatory triggers among chronically HIV-1 infected adults on stable anti-retroviral therapy at risk for cardiovascular disease. PLoS One. 2013; 8(9):e75500. PMID: 24086545.
      Citations: 28     Fields:    Translation:HumansCells
    104. Shikuma CM, Barbour JD, Ndhlovu LC, Keating SM, Norris PJ, Budoff M, Parikh N, Seto T, Gangcuangco LM, Ogata-Arakaki D, Chow D. Plasma monocyte chemoattractant protein-1 and tumor necrosis factor-a levels predict the presence of coronary artery calcium in HIV-infected individuals independent of traditional cardiovascular risk factors. AIDS Res Hum Retroviruses. 2014 Feb; 30(2):142-6. PMID: 23984974.
      Citations: 19     Fields:    Translation:Humans
    105. Chow D, Nakamoto B, So E, Parikh N, Souza S, Kallianpur K, Shikuma C. Rates of autonomic dysfunction in HIV patients receiving antiretroviral therapy. J Neurovirol. 2013 Oct; 19(5):511-2. PMID: 24018903.
      Citations: 5     Fields:    Translation:Humans
    106. Tongma C, Shikuma CM, Nakamoto BK, Kallianpur KJ, Umaki TM, Barbour JD, Ndhlovu L, Parikh NI, Chow DC. Albuminuria as a marker of cardiovascular risk in HIV-infected individuals receiving stable antiretroviral therapy. Hawaii J Med Public Health. 2013 Sep; 72(9 Suppl 4):34-8. PMID: 24052917.
      Citations: 4     Fields:    Translation:Humans
    107. Valcour VG, Ananworanich J, Agsalda M, Sailasuta N, Chalermchai T, Schuetz A, Shikuma C, Liang CY, Jirajariyavej S, Sithinamsuwan P, Tipsuk S, Clifford DB, Paul R, Fletcher JL, Marovich MA, Slike BM, DeGruttola V, Shiramizu B. HIV DNA reservoir increases risk for cognitive disorders in cART-na?ve patients. PLoS One. 2013; 8(7):e70164. PMID: 23936155.
      Citations: 57     Fields:    Translation:HumansCells
    108. Shikuma CM, McArthur JC, Ebenezer GJ, Ananworanich J, Teeratakulpisarn N, Jadwattanakul T, Valcour VG, Bennett K, Phanuphak N. Ethnic differences in epidermal nerve fiber density. Muscle Nerve. 2013 Sep; 48(3):462-4. PMID: 23483476.
      Citations: 8     Fields:    Translation:HumansCells
    109. Gangcuangco LM, Chow DC, Liang CY, Nakamoto BK, Umaki TM, Kallianpur KJ, Shikuma CM. Predictors of 25-hydroxyvitamin D levels in HIV-infected patients in Hawai'i. Hawaii J Med Public Health. 2013 Jun; 72(6):197-201. PMID: 23795329.
      Citations: 3     Fields:    Translation:Humans
    110. Kallianpur KJ, Shikuma C, Kirk GR, Shiramizu B, Valcour V, Chow D, Souza S, Nakamoto B, Sailasuta N. Peripheral blood HIV DNA is associated with atrophy of cerebellar and subcortical gray matter. Neurology. 2013 May 07; 80(19):1792-9. PMID: 23596064.
      Citations: 52     Fields:    Translation:Humans
    111. Lin C, Grandinetti A, Shikuma C, Souza S, Parikh N, Nakamoto B, Kallianpur KJ, Chow D. The effects of extended release niacin on lipoprotein sub-particle concentrations in HIV-infected patients. Hawaii J Med Public Health. 2013 Apr; 72(4):123-7. PMID: 23795312.
      Citations: 1     Fields:    Translation:Humans
    112. Chalermchai T, Valcour V, Sithinamsuwan P, Pinyakorn S, Clifford D, Paul RH, Tipsuk S, Fletcher JL, Degruttola V, Ratto-Kim S, Hutchings N, Shikuma C, Ananworanich J. Trail Making Test A improves performance characteristics of the International HIV Dementia Scale to identify symptomatic HAND. J Neurovirol. 2013 Apr; 19(2):137-43. PMID: 23483520.
      Citations: 13     Fields:    Translation:Humans
    113. Watt G, Kantipong P, Burnouf T, Shikuma C, Philpott S. Natural Scrub Typhus Antibody Suppresses HIV CXCR4(X4) Viruses. Infect Dis Rep. 2013 Jan 22; 5(1):e8. PMID: 24470959.
      Citations:    
    114. Jalbert E, Shikuma CM, Ndhlovu LC, Barbour JD. Sequential staining improves detection of CCR2 and CX3CR1 on monocytes when simultaneously evaluating CCR5 by multicolor flow cytometry. Cytometry A. 2013 Mar; 83(3):280-6. PMID: 23426986.
      Citations: 11     Fields:    Translation:HumansCells
    115. Phanuphak N, Ananworanich J, Teeratakulpisarn N, Jadwattanakul T, Kerr SJ, Chomchey N, Hongchookiat P, Mathajittiphun P, Pinyakorn S, Rungrojrat P, Praihirunyakit P, Gerschenson M, Phanuphak P, Valcour V, Kim JH, Shikuma C. A 72-week randomized study of the safety and efficacy of a stavudine to zidovudine switch at 24 weeks compared to zidovudine or tenofovir disoproxil fumarate when given with lamivudine and nevirapine. Antivir Ther. 2012; 17(8):1521-31. PMID: 23220732.
      Citations: 4     Fields:    Translation:HumansCTClinical Trials
    116. Heaps J, Valcour V, Chalermchai T, Paul R, Rattanamanee S, Siangphoe U, Sithinamsuwan P, Chairangsaris P, Nidhinandana S, Tipsuk S, Suttichom D, Fletcher J, Shikuma C, Ananworanich J. Development of normative neuropsychological performance in Thailand for the assessment of HIV-associated neurocognitive disorders. J Clin Exp Neuropsychol. 2013; 35(1):1-8. PMID: 23113809.
      Citations: 19     Fields:    Translation:Humans
    117. Krishnan S, Schouten JT, Atkinson B, Brown T, Wohl D, McComsey GA, Glesby MJ, Shikuma C, Haubrich R, Tebas P, Campbell TB, Jacobson DL. Metabolic syndrome before and after initiation of antiretroviral therapy in treatment-naive HIV-infected individuals. J Acquir Immune Defic Syndr. 2012 Nov 01; 61(3):381-9. PMID: 22828718.
      Citations: 38     Fields:    Translation:Humans
    118. Shikuma CM, Nakamoto B, Shiramizu B, Liang CY, DeGruttola V, Bennett K, Paul R, Kallianpur K, Chow D, Gavegnano C, Hurwitz SJ, Schinazi RF, Valcour VG. Antiretroviral monocyte efficacy score linked to cognitive impairment in HIV. Antivir Ther. 2012; 17(7):1233-42. PMID: 23018140.
      Citations: 43     Fields:    Translation:HumansCells
    119. Chow D, Kocher M, Shikuma C, Parikh N, Grandinetti A, Nakamoto B, Seto T, Low P. Effects of antiretroviral therapy on autonomic function in early HIV infection: a preliminary report. Int J Med Sci. 2012; 9(5):397-405. PMID: 22859899.
      Citations: 5     Fields:    Translation:Humans
    120. McLinden R, Paris R, Polonis V, Close N, Su Z, Shikuma C, Margolis D, Kim J. Association of HIV neutralizing antibody with lower viral load after treatment interruption in a prospective trial (A5170). AIDS. 2012 Jul 17; 26(11):1452. PMID: 22767347.
      Citations: 5     Fields:    Translation:HumansCells
    121. Chow D, Thomas BS, Liang CY, Souza SC, Nakamoto BK, Parikh NI, Shikuma C. Role of the veterans aging cohort study index in assessing total atherosclerotic burden. Clin Infect Dis. 2012 Sep; 55(5):750-1; author reply 751-2. PMID: 22670040.
      Citations: 3     Fields:    Translation:Humans
    122. Nakamoto BK, Jahanshad N, McMurtray A, Kallianpur KJ, Chow DC, Valcour VG, Paul RH, Marotz L, Thompson PM, Shikuma CM. Cerebrovascular risk factors and brain microstructural abnormalities on diffusion tensor images in HIV-infected individuals. J Neurovirol. 2012 Aug; 18(4):303-12. PMID: 22585287.
      Citations: 15     Fields:    Translation:Humans
    123. Shikuma C, Gerschenson M, Ananworanich J, Valcour V, Teeratakulpisarn N, Jadwattanakul T, Degruttola V, Liang CY, McArthur J, Ebenezer G, Chomchey N, Praihirunkit P, Hongchookiath P, Mathajittiphun P, Nakamoto B, Hauer P, Phanuphak P, Phanuphak N. Determinants of epidermal nerve fibre density in antiretroviral-na?ve HIV-infected individuals. HIV Med. 2012 Nov; 13(10):602-8. PMID: 22574621.
      Citations: 6     Fields:    Translation:HumansCells
    124. McLinden RJ, Paris RM, Polonis VR, Close NC, Su Z, Shikuma CM, Margolis DM, Kim JH. Association of HIV neutralizing antibody with lower viral load after treatment interruption in a prospective trial (A5170). AIDS. 2012 Jan 02; 26(1):1-9. PMID: 21971356.
      Citations: 2     Fields:    Translation:HumansCells
    125. Kusao I, Shiramizu B, Liang CY, Grove J, Agsalda M, Troelstrup D, Velasco VN, Marshall A, Whitenack N, Shikuma C, Valcour V. Cognitive performance related to HIV-1-infected monocytes. J Neuropsychiatry Clin Neurosci. 2012; 24(1):71-80. PMID: 22450616.
      Citations: 55     Fields:    Translation:HumansCells
    126. Shimizu SM, Chow DC, Valcour V, Masaki K, Nakamoto B, Kallianpur KJ, Shikuma C. The Impact of Depressive Symptoms on Neuropsychological Performance Tests in HIV-Infected Individuals: A Study of the Hawaii Aging with HIV Cohort. World J AIDS. 2011 Dec 01; 1(4):139-145. PMID: 23061029.
      Citations:    
    127. Shikuma CM, Seto T, Liang CY, Bennett K, DeGruttola V, Gerschenson M, Stein JH, Budoff M, Hodis HN, Delaney JA, Ogata-Arakaki D, Pramyothin P, Chow D. Vitamin D levels and markers of arterial dysfunction in HIV. AIDS Res Hum Retroviruses. 2012 Aug; 28(8):793-7. PMID: 21978287.
      Citations: 33     Fields:    Translation:Humans
    128. Kallianpur KJ, Kirk GR, Sailasuta N, Valcour V, Shiramizu B, Nakamoto BK, Shikuma C. Regional cortical thinning associated with detectable levels of HIV DNA. Cereb Cortex. 2012 Sep; 22(9):2065-75. PMID: 22016479.
      Citations: 53     Fields:    Translation:Humans
    129. Nakamoto BK, Valcour VG, Kallianpur K, Liang CY, McMurtray A, Chow D, Kappenburg E, Shikuma CM. Impact of cerebrovascular disease on cognitive function in HIV-infected patients. J Acquir Immune Defic Syndr. 2011 Jul 01; 57(3):e66-8. PMID: 21860354.
      Citations: 11     Fields:    Translation:Humans
    130. Chow DC, Wood R, Choi J, Grandinetti A, Gerschenson M, Sriratanaviriyakul N, Nakamoto B, Shikuma C, Low P. Cardiovagal autonomic function in HIV-infected patients with unsuppressed HIV viremia. HIV Clin Trials. 2011 May-Jun; 12(3):141-50. PMID: 21684854.
      Citations: 16     Fields:    Translation:Humans
    131. Le T, Wolbers M, Chi NH, Quang VM, Chinh NT, Lan NP, Lam PS, Kozal MJ, Shikuma CM, Day JN, Farrar J. Epidemiology, seasonality, and predictors of outcome of AIDS-associated Penicillium marneffei infection in Ho Chi Minh City, Viet Nam. Clin Infect Dis. 2011 Apr 01; 52(7):945-52. PMID: 21427403.
      Citations: 96     Fields:    Translation:HumansAnimals
    132. Le T, Farrar J, Shikuma C. Rebound of plasma viremia following cessation of antiretroviral therapy despite profoundly low levels of HIV reservoir: implications for eradication. AIDS. 2011 Mar 27; 25(6):871-2; author reply 872-3. PMID: 21412062.
      Citations: 4     Fields:    Translation:HumansCells
    133. Payam A, Shiramizu B, Shikuma C, Milne C, Terada K, Kajioka E, Ka'opua LS, Cassel K, Chow D. HIV-associated anal dysplasia: experience from a multiethnic-HIV clinic in Hawaii. J Health Care Poor Underserved. 2011; 22(4 Suppl):16-22. PMID: 22102303.
      Citations: 1     Fields:    Translation:HumansCellsPHPublic Health
    134. Valcour V, Paul R, Neuhaus J, Shikuma C. The Effects of Age and HIV on Neuropsychological Performance. J Int Neuropsychol Soc. 2011 Jan; 17(1):190-5. PMID: 21144102.
      Citations: 58     Fields:    Translation:Humans
    135. Shikuma CM, Ribaudo HJ, Zheng Y, Gulick RM, Meyer WA, Tashima KT, Bastow B, Kuritzkes DR, Glesby MJ. Change in high-sensitivity c-reactive protein levels following initiation of efavirenz-based antiretroviral regimens in HIV-infected individuals. AIDS Res Hum Retroviruses. 2011 May; 27(5):461-8. PMID: 20863238.
      Citations: 23     Fields:    Translation:Humans
    136. Le T, Huu Chi N, Kim Cuc NT, Manh Sieu TP, Shikuma CM, Farrar J, Day JN. AIDS-associated Penicillium marneffei infection of the central nervous system. Clin Infect Dis. 2010 Dec 15; 51(12):1458-62. PMID: 21054180.
      Citations: 23     Fields:    Translation:HumansAnimals
    137. Pereyra F, Jia X, McLaren PJ, Telenti A, de Bakker PI, Walker BD, Ripke S, Brumme CJ, Pulit SL, Carrington M, Kadie CM, Carlson JM, Heckerman D, Graham RR, Plenge RM, Deeks SG, Gianniny L, Crawford G, Sullivan J, Gonzalez E, Davies L, Camargo A, Moore JM, Beattie N, Gupta S, Crenshaw A, Burtt NP, Guiducci C, Gupta N, Gao X, Qi Y, Yuki Y, Piechocka-Trocha A, Cutrell E, Rosenberg R, Moss KL, Lemay P, O'Leary J, Schaefer T, Verma P, Toth I, Block B, Baker B, Rothchild A, Lian J, Proudfoot J, Alvino DM, Vine S, Addo MM, Allen TM, Altfeld M, Henn MR, Le Gall S, Streeck H, Haas DW, Kuritzkes DR, Robbins GK, Shafer RW, Gulick RM, Shikuma CM, Haubrich R, Riddler S, Sax PE, Daar ES, Ribaudo HJ, Agan B, Agarwal S, Ahern RL, Allen BL, Altidor S, Altschuler EL, Ambardar S, Anastos K, Anderson B, Anderson V, Andrady U, Antoniskis D, Bangsberg D, Barbaro D, Barrie W, Bartczak J, Barton S, Basden P, Basgoz N, Bazner S, Bellos NC, Benson AM, Berger J, Bernard NF, Bernard AM, Birch C, Bodner SJ, Bolan RK, Boudreaux ET, Bradley M, Braun JF, Brndjar JE, Brown SJ, Brown K, Brown ST, Burack J, Bush LM, Cafaro V, Campbell O, Campbell J, Carlson RH, Carmichael JK, Casey KK, Cavacuiti C, Celestin G, Chambers ST, Chez N, Chirch LM, Cimoch PJ, Cohen D, Cohn LE, Conway B, Cooper DA, Cornelson B, Cox DT, Cristofano MV, Cuchural G, Czartoski JL, Dahman JM, Daly JS, Davis BT, Davis K, Davod SM, DeJesus E, Dietz CA, Dunham E, Dunn ME, Ellerin TB, Eron JJ, Fangman JJ, Farel CE, Ferlazzo H, Fidler S, Fleenor-Ford A, Frankel R, Freedberg KA, French NK, Fuchs JD, Fuller JD, Gaberman J, Gallant JE, Gandhi RT, Garcia E, Garmon D, Gathe JC, Gaultier CR, Gebre W, Gilman FD, Gilson I, Goepfert PA, Gottlieb MS, Goulston C, Groger RK, Gurley TD, Haber S, Hardwicke R, Hardy WD, Harrigan PR, Hawkins TN, Heath S, Hecht FM, Henry WK, Hladek M, Hoffman RP, Horton JM, Hsu RK, Huhn GD, Hunt P, Hupert MJ, Illeman ML, Jaeger H, Jellinger RM, John M, Johnson JA, Johnson KL, Johnson H, Johnson K, Joly J, Jordan WC, Kauffman CA, Khanlou H, Killian RK, Kim AY, Kim DD, Kinder CA, Kirchner JT, Kogelman L, Kojic EM, Korthuis PT, Kurisu W, Kwon DS, LaMar M, Lampiris H, Lanzafame M, Lederman MM, Lee DM, Lee JM, Lee MJ, Lee ET, Lemoine J, Levy JA, Llibre JM, Liguori MA, Little SJ, Liu AY, Lopez AJ, Loutfy MR, Loy D, Mohammed DY, Man A, Mansour MK, Marconi VC, Markowitz M, Marques R, Martin JN, Martin HL, Mayer KH, McElrath MJ, McGhee TA, McGovern BH, McGowan K, McIntyre D, Mcleod GX, Menezes P, Mesa G, Metroka CE, Meyer-Olson D, Miller AO, Montgomery K, Mounzer KC, Nagami EH, Nagin I, Nahass RG, Nelson MO, Nielsen C, Norene DL, O'Connor DH, Ojikutu BO, Okulicz J, Oladehin OO, Oldfield EC, Olender SA, Ostrowski M, Owen WF, Pae E, Parsonnet J, Pavlatos AM, Perlmutter AM, Pierce MN, Pincus JM, Pisani L, Price LJ, Proia L, Prokesch RC, Pujet HC, Ramgopal M, Rathod A, Rausch M, Ravishankar J, Rhame FS, Richards CS, Richman DD, Rodes B, Rodriguez M, Rose RC, Rosenberg ES, Rosenthal D, Ross PE, Rubin DS, Rumbaugh E, Saenz L, Salvaggio MR, Sanchez WC, Sanjana VM, Santiago S, Schmidt W, Schuitemaker H, Sestak PM, Shalit P, Shay W, Shirvani VN, Silebi VI, Sizemore JM, Skolnik PR, Sokol-Anderson M, Sosman JM, Stabile P, Stapleton JT, Starrett S, Stein F, Stellbrink HJ, Sterman FL, Stone VE, Stone DR, Tambussi G, Taplitz RA, Tedaldi EM, Telenti A, Theisen W, Torres R, Tosiello L, Tremblay C, Tribble MA, Trinh PD, Tsao A, Ueda P, Vaccaro A, Valadas E, Vanig TJ, Vecino I, Vega VM, Veikley W, Wade BH, Walworth C, Wanidworanun C, Ward DJ, Warner DA, Weber RD, Webster D, Weis S, Wheeler DA, White DJ, Wilkins E, Winston A, Wlodaver CG, van't Wout A, Wright DP, Yang OO, Yurdin DL, Zabukovic BW, Zachary KC, Zeeman B, Zhao M. The major genetic determinants of HIV-1 control affect HLA class I peptide presentation. Science. 2010 Dec 10; 330(6010):1551-7. PMID: 21051598.
      Citations: 707     Fields:    Translation:HumansCells
    138. Le T, Hong Chau TT, Kim Cuc NT, Si Lam P, Manh Sieu TP, Shikuma CM, Day JN. AIDS-associated Cryptococcus neoformans and Penicillium marneffei coinfection: a therapeutic dilemma in resource-limited settings. Clin Infect Dis. 2010 Nov 01; 51(9):e65-8. PMID: 20887205.
      Citations: 8     Fields:    Translation:HumansAnimals
    139. Brown TT, Tassiopoulos K, Bosch RJ, Shikuma C, McComsey GA. Association between systemic inflammation and incident diabetes in HIV-infected patients after initiation of antiretroviral therapy. Diabetes Care. 2010 Oct; 33(10):2244-9. PMID: 20664016.
      Citations: 128     Fields:    Translation:Humans
    140. Nakamoto BK, McMurtray A, Davis J, Valcour V, Watters MR, Shiramizu B, Chow DC, Kallianpur K, Shikuma CM. Incident neuropathy in HIV-infected patients on HAART. AIDS Res Hum Retroviruses. 2010 Jul; 26(7):759-65. PMID: 20624077.
      Citations: 10     Fields:    Translation:Humans
    141. Souza SA, Chow DC, Walsh EJ, Ford S, Shikuma C. Pilot study on the safety and tolerability of extended release niacin for HIV-infected patients with hypertriglyceridemia. Hawaii Med J. 2010 May; 69(5):122-5. PMID: 20533755.
      Citations: 1     Fields:    Translation:Humans
    142. Chow DC, Stein JH, Seto TB, Mitchell C, Sriratanaviriyakul N, Grandinetti A, Gerschenson M, Shiramizu B, Souza S, Shikuma C. Short-term effects of extended-release niacin on endothelial function in HIV-infected patients on stable antiretroviral therapy. AIDS. 2010 Apr 24; 24(7):1019-23. PMID: 20216298.
      Citations: 8     Fields:    Translation:HumansCells
    143. Paredes R, Lalama CM, Ribaudo HJ, Schackman BR, Shikuma C, Giguel F, Meyer WA, Johnson VA, Fiscus SA, D'Aquila RT, Gulick RM, Kuritzkes DR. Pre-existing minority drug-resistant HIV-1 variants, adherence, and risk of antiretroviral treatment failure. J Infect Dis. 2010 Mar; 201(5):662-71. PMID: 20102271.
      Citations: 92     Fields:    Translation:HumansCells
    144. Schouten JT, Krambrink A, Ribaudo HJ, Kmack A, Webb N, Shikuma C, Kuritzkes DR, Gulick RM. Substitution of nevirapine because of efavirenz toxicity in AIDS clinical trials group A5095. Clin Infect Dis. 2010 Mar 01; 50(5):787-91. PMID: 20121419.
      Citations: 11     Fields:    Translation:Humans
    145. Valcour VG, Shiramizu BT, Shikuma CM. HIV DNA in circulating monocytes as a mechanism to dementia and other HIV complications. J Leukoc Biol. 2010 Apr; 87(4):621-6. PMID: 20130221.
      Citations: 56     Fields:    Translation:HumansCells
    146. Pumpradit W, Ananworanich J, Lolak S, Shikuma C, Paul R, Siangphoe U, Chaoniti N, Kaew-On P, Paris R, Ruxrungtham K, Valcour V. Neurocognitive impairment and psychiatric comorbidity in well-controlled human immunodeficiency virus-infected Thais from the 2NN Cohort Study. J Neurovirol. 2010 Feb; 16(1):76-82. PMID: 20053142.
      Citations: 24     Fields:    Translation:HumansCells
    147. Hu W, Yu Q, Hu N, Byrd D, Amet T, Shikuma C, Shiramizu B, Halperin JA, Qin X. A high-affinity inhibitor of human CD59 enhances complement-mediated virolysis of HIV-1: implications for treatment of HIV-1/AIDS. J Immunol. 2010 Jan 01; 184(1):359-68. PMID: 19955519.
      Citations: 28     Fields:    Translation:HumansCells
    148. Hetzler RK, Stickley CD, Shikuma CM, Chow D, Takahashi CE, Kimura IF, Barnett AT. Validation of the human activity profile in HIV-positive individuals on HAART. HIV Clin Trials. 2009 Jul-Aug; 10(4):254-60. PMID: 19723612.
      Citations: 1     Fields:    Translation:HumansCells
    149. Marten LR, Chow DC, Valcour NA, Shikuma CM. Assessing the needs for HIV medical care in Hawai'i. Hawaii Med J. 2009 May; 68(4):74-8. PMID: 19583108.
      Citations: 2     Fields:    Translation:Humans
    150. Hu N, Yu R, Shikuma C, Shiramizu B, Ostrwoski MA, Yu Q. Role of cell signaling in poxvirus-mediated foreign gene expression in mammalian cells. Vaccine. 2009 May 14; 27(22):2994-3006. PMID: 19428911.
      Citations: 8     Fields:    Translation:HumansAnimalsCells
    151. Chow D, Okinaka L, Souza S, Shikuma C, Tice A. Hansen's disease with HIV: a case of immune reconstitution disease. Hawaii Med J. 2009 Mar; 68(2):27-9. PMID: 19385373.
      Citations: 2     Fields:    Translation:Humans
    152. Shiramizu B, Williams AE, Shikuma C, Valcour V. Amount of HIV DNA in peripheral blood mononuclear cells is proportional to the severity of HIV-1-associated neurocognitive disorders. J Neuropsychiatry Clin Neurosci. 2009; 21(1):68-74. PMID: 19359454.
      Citations: 25     Fields:    Translation:HumansCells
    153. Sithinamsuwan P, Punthanamongkol S, Valcour V, Onsanit S, Nidhinandana S, Thitivichianlert S, Shikuma C. Frequency and characteristics of HIV-associated sensory neuropathy among HIV patients in Bangkok, Thailand. J Acquir Immune Defic Syndr. 2008 Dec 01; 49(4):456-8. PMID: 19011422.
      Citations: 6     Fields:    Translation:Humans
    154. Valcour V, Watters MR, Williams AE, Sacktor N, McMurtray A, Shikuma C. Aging exacerbates extrapyramidal motor signs in the era of highly active antiretroviral therapy. J Neurovirol. 2008 Oct; 14(5):362-7. PMID: 18989814.
      Citations: 48     Fields:    Translation:HumansCells
    155. Valcour V, Shiramizu B, Shikuma C. Frequency of apolipoprotein E4 among older compared with younger HIV patients: support for detrimental effect of E4 on survival. Proc Natl Acad Sci U S A. 2008 Oct 14; 105(41):E66; author reply E67-8. PMID: 18843101.
      Citations: 11     Fields:    Translation:Humans
    156. Ananworanich J, Phanuphak N, de Souza M, Paris R, Arroyo M, Trichavaroj R, Sirivichayakul S, Shikuma C, Phanuphak P, Kim JH. Incidence and characterization of acute HIV-1 infection in a high-risk Thai population. J Acquir Immune Defic Syndr. 2008 Oct 01; 49(2):151-5. PMID: 18769355.
      Citations: 24     Fields:    Translation:HumansCells
    157. Shikuma CM, Gerschenson M, Chow D, Libutti DE, Willis JH, Murray J, Capaldi RA, Marusich M. Mitochondrial oxidative phosphorylation protein levels in peripheral blood mononuclear cells correlate with levels in subcutaneous adipose tissue within samples differing by HIV and lipoatrophy status. AIDS Res Hum Retroviruses. 2008 Oct; 24(10):1255-62. PMID: 18844460.
      Citations: 16     Fields:    Translation:HumansCells
    158. Kaholokula JK, Saito E, Shikuma C, Look M, Spencer-Tolentino K, Mau MK. Native and Pacific health disparities research. Hawaii Med J. 2008 Aug; 67(8):218-9, 222. PMID: 18853894.
      Citations: 5     Fields:    Translation:Humans
    159. Kuritzkes DR, Lalama CM, Ribaudo HJ, Marcial M, Meyer WA, Shikuma C, Johnson VA, Fiscus SA, D'Aquila RT, Schackman BR, Acosta EP, Gulick RM. Preexisting resistance to nonnucleoside reverse-transcriptase inhibitors predicts virologic failure of an efavirenz-based regimen in treatment-naive HIV-1-infected subjects. J Infect Dis. 2008 Mar 15; 197(6):867-70. PMID: 18269317.
      Citations: 67     Fields:    Translation:HumansCells
    160. Ratto-Kim S, Chuenchitra T, Pulliam L, Paris R, Sukwit S, Gongwon S, Sithinamsuwan P, Nidhinandana S, Thitivichianlert S, Shiramizu BT, de Souza MS, Chitpatima ST, Sun B, Rempel H, Nitayaphan S, Williams K, Kim JH, Shikuma CM, Valcour VG. Expression of monocyte markers in HIV-1 infected individuals with or without HIV associated dementia and normal controls in Bangkok Thailand. J Neuroimmunol. 2008 Mar; 195(1-2):100-7. PMID: 18191233.
      Citations: 7     Fields:    Translation:HumansCells
    161. Tebas P, Zhang J, Yarasheski K, Evans S, Fischl MA, Shevitz A, Feinberg J, Collier AC, Shikuma C, Brizz B, Sattler F. Switching to a protease inhibitor-containing, nucleoside-sparing regimen (lopinavir/ritonavir plus efavirenz) increases limb fat but raises serum lipid levels: results of a prospective randomized trial (AIDS clinical trial group 5125s). J Acquir Immune Defic Syndr. 2007 Jun 01; 45(2):193-200. PMID: 17527093.
      Citations: 12     Fields:    Translation:Humans
    162. Sacktor N, Skolasky R, Selnes OA, Watters M, Poff P, Shiramizu B, Shikuma C, Valcour V. Neuropsychological test profile differences between young and old human immunodeficiency virus-positive individuals. J Neurovirol. 2007 Jun; 13(3):203-9. PMID: 17613710.
      Citations: 59     Fields:    Translation:Humans
    163. Gulick RM, Lalama CM, Ribaudo HJ, Shikuma CM, Schackman BR, Schouten J, Squires KE, Koletar SL, Pilcher CD, Reichman RC, Klingman KL, Kuritzkes DR. Intensification of a triple-nucleoside regimen with tenofovir or efavirenz in HIV-1-infected patients with virological suppression. AIDS. 2007 Apr 23; 21(7):813-23. PMID: 17415036.
      Citations: 5     Fields:    Translation:HumansCells
    164. Shikuma CM, Yang Y, Glesby MJ, Meyer WA, Tashima KT, Ribaudo HJ, Webb N, Bastow B, Kuritzkes DR, Gulick RM. Metabolic effects of protease inhibitor-sparing antiretroviral regimens given as initial treatment of HIV-1 Infection (AIDS Clinical Trials Group Study A5095). J Acquir Immune Defic Syndr. 2007 Apr 15; 44(5):540-50. PMID: 17245230.
      Citations: 21     Fields:    Translation:HumansCells
    165. Kuritzkes DR, Ribaudo HJ, Squires KE, Koletar SL, Santana J, Riddler SA, Reichman R, Shikuma C, Meyer WA, Klingman KL, Gulick RM. Plasma HIV-1 RNA dynamics in antiretroviral-naive subjects receiving either triple-nucleoside or efavirenz-containing regimens: ACTG A5166s. J Infect Dis. 2007 Apr 15; 195(8):1169-76. PMID: 17357053.
      Citations: 23     Fields:    Translation:HumansCells
    166. Shiramizu B, Paul R, Williams A, Shikuma C, Watters M, Grove J, Valcour V. HIV proviral DNA associated with decreased neuropsychological function. J Neuropsychiatry Clin Neurosci. 2007; 19(2):157-63. PMID: 17431062.
      Citations: 20     Fields:    Translation:HumansCells
    167. Khawcharoenporn T, Shikuma CM, Williams AE, Chow DC. Lamivudine-associated macrocytosis in HIV-infected patients. Int J STD AIDS. 2007 Jan; 18(1):39-40. PMID: 17326861.
      Citations:    Fields:    Translation:HumansCells
    168. Bhasin S, Parker RA, Sattler F, Haubrich R, Alston B, Umbleja T, Shikuma CM. Effects of testosterone supplementation on whole body and regional fat mass and distribution in human immunodeficiency virus-infected men with abdominal obesity. J Clin Endocrinol Metab. 2007 Mar; 92(3):1049-57. PMID: 17164307.
      Citations: 31     Fields:    Translation:HumansCells
    169. Shiramizu B, Ratto-Kim S, Sithinamsuwan P, Nidhinandana S, Thitivichianlert S, Watt G, deSouza M, Chuenchitra T, Sukwit S, Chitpatima S, Robertson K, Paul R, Shikuma C, Valcour V. HIV DNA and dementia in treatment-na?ve HIV-1-infected individuals in Bangkok, Thailand. Int J Med Sci. 2006 Dec 06; 4(1):13-8. PMID: 17211496.
      Citations: 17     Fields:    Translation:HumansCells
    170. Valcour VG, Sacktor NC, Paul RH, Watters MR, Selnes OA, Shiramizu BT, Williams AE, Shikuma CM. Insulin resistance is associated with cognition among HIV-1-infected patients: the Hawaii Aging With HIV cohort. J Acquir Immune Defic Syndr. 2006 Dec 01; 43(4):405-10. PMID: 17099311.
      Citations: 54     Fields:    Translation:HumansCells
    171. Valcour V, Yee P, Williams AE, Shiramizu B, Watters M, Selnes O, Paul R, Shikuma C, Sacktor N. Lowest ever CD4 lymphocyte count (CD4 nadir) as a predictor of current cognitive and neurological status in human immunodeficiency virus type 1 infection--The Hawaii Aging with HIV Cohort. J Neurovirol. 2006 Oct; 12(5):387-91. PMID: 17065131.
      Citations: 67     Fields:    Translation:Humans
    172. Chow DC, Day LJ, Souza SA, Shikuma CM. Metabolic complications of HIV therapy. IAPAC Mon. 2006 Sep; 12(9):302-17. PMID: 17378067.
      Citations: 1     Fields:    Translation:Humans
    173. Gulick RM, Ribaudo HJ, Shikuma CM, Lalama C, Schackman BR, Meyer WA, Acosta EP, Schouten J, Squires KE, Pilcher CD, Murphy RL, Koletar SL, Carlson M, Reichman RC, Bastow B, Klingman KL, Kuritzkes DR. Three- vs four-drug antiretroviral regimens for the initial treatment of HIV-1 infection: a randomized controlled trial. JAMA. 2006 Aug 16; 296(7):769-81. PMID: 16905783.
      Citations: 91     Fields:    Translation:HumansCells
    174. Chow DC, Wood R, Grandinetti A, Shikuma C, Schatz I, Low P. Cardiovagal autonomic dysfunction in relation to HIV-associated lipodystrophy. HIV Clin Trials. 2006 Jan-Feb; 7(1):16-23. PMID: 16684641.
      Citations: 4     Fields:    Translation:HumansCellsCTClinical Trials
    175. Ribaudo HJ, Kuritzkes DR, Schackman BR, Acosta EP, Shikuma CM, Gulick RM. Design issues in initial HIV-treatment trials: focus on ACTG A5095. Antivir Ther. 2006; 11(6):751-60. PMID: 17310819.
      Citations: 6     Fields:    Translation:HumansCells
    176. Shikuma CM, Day LJ, Gerschenson M. Insulin resistance in the HIV-infected population: the potential role of mitochondrial dysfunction. Curr Drug Targets Infect Disord. 2005 Sep; 5(3):255-62. PMID: 16181144.
      Citations: 20     Fields:    Translation:Humans
    177. Shikuma CM, Valcour VG, Ratto-Kim S, Williams AE, Souza S, Gerschenson M, Day L, Kim JH, Shiramizu B. HIV-associated wasting in the era of highly active antiretroviral therapy: a syndrome of residual HIV infection in monocytes and macrophages? Clin Infect Dis. 2005 Jun 15; 40(12):1846-8. PMID: 15909275.
      Citations: 5     Fields:    Translation:HumansCells
    178. Shiramizu B, Gartner S, Williams A, Shikuma C, Ratto-Kim S, Watters M, Aguon J, Valcour V. Circulating proviral HIV DNA and HIV-associated dementia. AIDS. 2005 Jan 03; 19(1):45-52. PMID: 15627032.
      Citations: 68     Fields:    Translation:HumansCells
    179. Valcour VG, Shikuma CM, Shiramizu BT, Williams AE, Watters MR, Poff PW, Grove JS, Selnes OA, Sacktor NC. Diabetes, insulin resistance, and dementia among HIV-1-infected patients. J Acquir Immune Defic Syndr. 2005 Jan 01; 38(1):31-6. PMID: 15608521.
      Citations: 58     Fields:    Translation:HumansCells
    180. Gerschenson M, Shiramizu B, LiButti DE, Shikuma CM. Mitochondrial DNA levels of peripheral blood mononuclear cells and subcutaneous adipose tissue from thigh, fat and abdomen of HIV-1 seropositive and negative individuals. Antivir Ther. 2005; 10 Suppl 2:M83-9. PMID: 16152709.
      Citations: 21     Fields:    Translation:HumansCells
    181. Day L, Shikuma C, Gerschenson M. Acetyl-L-carnitine for the treatment of HIV lipoatrophy. Ann N Y Acad Sci. 2004 Nov; 1033:139-46. PMID: 15591011.
      Citations:    Fields:    Translation:HumansCells
    182. Shikuma CM, Zackin R, Sattler F, Mildvan D, Nyangweso P, Alston B, Evans S, Mulligan K. Changes in weight and lean body mass during highly active antiretroviral therapy. Clin Infect Dis. 2004 Oct 15; 39(8):1223-30. PMID: 15486848.
      Citations: 30     Fields:    Translation:Humans
    183. Day L, Shikuma C, Gerschenson M. Mitochondrial injury in the pathogenesis of antiretroviral-induced hepatic steatosis and lactic acidemia. Mitochondrion. 2004 Jul; 4(2-3):95-109. PMID: 16120375.
      Citations: 5     Fields:    
    184. Gulick RM, Ribaudo HJ, Shikuma CM, Lustgarten S, Squires KE, Meyer WA, Acosta EP, Schackman BR, Pilcher CD, Murphy RL, Maher WE, Witt MD, Reichman RC, Snyder S, Klingman KL, Kuritzkes DR. Triple-nucleoside regimens versus efavirenz-containing regimens for the initial treatment of HIV-1 infection. N Engl J Med. 2004 Apr 29; 350(18):1850-61. PMID: 15115831.
      Citations: 160     Fields:    Translation:HumansCellsCTClinical Trials
    185. Valcour VG, Shikuma CM, Watters MR, Sacktor NC. Cognitive impairment in older HIV-1-seropositive individuals: prevalence and potential mechanisms. AIDS. 2004 Jan 01; 18 Suppl 1:S79-86. PMID: 15075502.
      Citations: 91     Fields:    Translation:HumansCells
    186. Shiramizu B, Gartner S, Cho M, Liu Y, Pyron N, Valcour V, Shikuma C. Assessment of HIV-1 DNA copies per cell by real-time polymerase chain reaction. Front Biosci. 2004 Jan 01; 9:255-61. PMID: 14766363.
      Citations: 5     Fields:    Translation:HumansCells
    187. Chow DC, Souza SA, Chen R, Richmond-Crum SM, Grandinetti A, Shikuma C. Elevated blood pressure in HIV-infected individuals receiving highly active antiretroviral therapy. HIV Clin Trials. 2003 Nov-Dec; 4(6):411-6. PMID: 14628284.
      Citations: 28     Fields:    Translation:Humans
    188. Shiramizu B, Shikuma KM, Kamemoto L, Gerschenson M, Erdem G, Pinti M, Cossarizza A, Shikuma C. Placenta and cord blood mitochondrial DNA toxicity in HIV-infected women receiving nucleoside reverse transcriptase inhibitors during pregnancy. J Acquir Immune Defic Syndr. 2003 Apr 01; 32(4):370-4. PMID: 12640193.
      Citations: 33     Fields:    Translation:HumansCellsPHPublic Health
    189. Wallis RS, Kalayjian R, Jacobson JM, Fox L, Purdue L, Shikuma CM, Arakaki R, Snyder S, Coombs RW, Bosch RJ, Spritzler J, Chernoff M, Aga E, Myers L, Schock B, Lederman MM. A study of the immunology, virology, and safety of prednisone in HIV-1-infected subjects with CD4 cell counts of 200 to 700 mm(-3). J Acquir Immune Defic Syndr. 2003 Mar 01; 32(3):281-6. PMID: 12626887.
      Citations: 15     Fields:    Translation:HumansCellsCTClinical Trials
    190. Chow DC, Richmond-Crum SM, Shimizu SM, Kohatsu J, Souza SA, Grandinetti A, Urada KK, Shikuma C. A descriptive epidemiologic study of HIV-infected individuals in Hawaii: report of the Hawaii Sero-Positivity and Medical Management database (HSPAMM). Hawaii Med J. 2002 Dec; 61(12):275-9. PMID: 12632825.
      Citations:    Fields:    Translation:Humans
    191. Chung RT, Evans SR, Yang Y, Theodore D, Valdez H, Clark R, Shikuma C, Nevin T, Sherman KE. Immune recovery is associated with persistent rise in hepatitis C virus RNA, infrequent liver test flares, and is not impaired by hepatitis C virus in co-infected subjects. AIDS. 2002 Sep 27; 16(14):1915-23. PMID: 12351951.
      Citations: 37     Fields:    Translation:Humans
    192. Yu Q, Shiramizu B, Nerurkar VR, Hu N, Shikuma CM, Melish ME, Cascio K, Imrie A, Lu Y, Yanagihara R. TT virus: preferential distribution in CD19(+) peripheral blood mononuclear cells and lack of viral integration. J Med Virol. 2002 Feb; 66(2):276-84. PMID: 11782940.
      Citations: 4     Fields:    Translation:HumansCells
    193. Shikuma CM, Shiramizu B. Mitochondrial Toxicity Associated with Nucleoside Reverse Transcriptase Inhibitor Therapy. Curr Infect Dis Rep. 2001 Dec; 3(6):553-560. PMID: 11722814.
      Citations:    
    194. Shikuma CM, Hu N, Milne C, Yost F, Waslien C, Shimizu S, Shiramizu B. Mitochondrial DNA decrease in subcutaneous adipose tissue of HIV-infected individuals with peripheral lipoatrophy. AIDS. 2001 Sep 28; 15(14):1801-9. PMID: 11579242.
      Citations: 22     Fields:    Translation:HumansCells
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