Macrophages

"Macrophages" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure, which enables searching at various levels of specificity.

MeSH information

Definition | Details | More General Concepts | Related Concepts | More Specific Concepts

The relatively long-lived phagocytic cell of mammalian tissues that are derived from blood MONOCYTES. Main types are PERITONEAL MACROPHAGES; ALVEOLAR MACROPHAGES; HISTIOCYTES; KUPFFER CELLS of the liver; and OSTEOCLASTS. They may further differentiate within chronic inflammatory lesions to EPITHELIOID CELLS or may fuse to form FOREIGN BODY GIANT CELLS or LANGHANS GIANT CELLS. (from The Dictionary of Cell Biology, Lackie and Dow, 3rd ed.)

Descriptor ID	D008264
MeSH Number(s)	A11.329.372 A11.627.482 A11.733.397 A15.382.680.397 A15.382.812.522
Concept/Terms	Macrophages Macrophages Bone Marrow-Derived Macrophages Bone Marrow Derived Macrophages Bone Marrow-Derived Macrophage Macrophage, Bone Marrow-Derived Macrophages, Bone Marrow-Derived Monocyte-Derived Macrophages Monocyte Derived Macrophages Macrophage Macrophages, Monocyte-Derived Macrophage, Monocyte-Derived Macrophages, Monocyte Derived Monocyte-Derived Macrophage

Below are MeSH descriptors whose meaning is more general than "Macrophages".

Anatomy [A]
Cells [A11]
Connective Tissue Cells [A11.329]
Macrophages [A11.329.372]
Myeloid Cells [A11.627]
Macrophages [A11.627.482]
Phagocytes [A11.733]
Macrophages [A11.733.397]
Hemic and Immune Systems [A15]
Immune System [A15.382]
Phagocytes [A15.382.680]
Macrophages [A15.382.680.397]
Mononuclear Phagocyte System [A15.382.812]
Macrophages [A15.382.812.522]

Below are MeSH descriptors whose meaning is related to "Macrophages".

Below are MeSH descriptors whose meaning is more specific than "Macrophages".

publications

Timeline | Most Recent

This graph shows the total number of publications written about "Macrophages" by people in this website by year, and whether "Macrophages" was a major or minor topic of these publications.

Bar chart showing 390 publications over 30 distinct years, with a maximum of 21 publications in 2004 and 2012 and 2014 and 2020

To see the data from this visualization as text, click here.

Year	Major Topic	Minor Topic	Total
1997	0	1	1
1998	1	4	5
1999	1	0	1
2000	0	3	3
2001	1	6	7
2002	3	7	10
2003	7	8	15
2004	9	12	21
2005	5	6	11
2006	5	3	8
2007	5	10	15
2008	7	6	13
2009	4	5	9
2010	9	7	16
2011	12	6	18
2012	9	12	21
2013	11	9	20
2014	12	9	21
2015	13	3	16
2016	10	10	20
2017	4	9	13
2018	13	3	16
2019	10	10	20
2020	12	9	21
2021	7	7	14
2022	1	6	7
2023	1	10	11
2024	6	9	15
2025	8	7	15
2026	2	5	7

Below are the most recent publications written about "Macrophages" by people in Profiles.

Shake EP, Vargas Santos G, Sivaraman V. Alcohol and Cannabinoids Differentially Regulate Macrophage Polarization, with Co-Exposure Producing an Antagonistic Immunomodulatory Effect. Int J Mol Sci. 2026 Apr 30; 27(9).

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Kumaresan V, Pahari S, Hung CY, Hermann BP, Schlesinger LS, Seshu J. Role of dual specificity phosphatase 1 in influencing inflammatory pathways in macrophages modulated by Borrelia burgdorferi lipoproteins. Front Immunol. 2026; 17:1766756.

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Tanoto FR, Liew JH, Stocks CJ, Rawat D, Chong KKL, Pethe K, Antypas H, Kline KA. Gelatinase regulates the egress of intracellular replicating populations during Enterococcus faecalis infection. PLoS Pathog. 2026 Mar; 22(3):e1013738.

View in: PubMed
Zalucha EM, Hutch CR, Bethea M, Cook TM, Unadkat A, Wells KL, Kim KS, Maerz B, Lehrke M, Singer K, Sandoval DA. The Role of Pancreatic Preproglucagon in Regulating Local Inflammation in Mice. Cells. 2026 Mar 06; 15(5).

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Armina-Rodriguez A, Dorta-Estremera SM, Mendez LB, Espino AM. Protection of mice against septic shock induced by lethal intraperitoneal dose of LPS by a recombinant Fasciola hepatica fatty acid binding protein. Microbiol Spectr. 2026 Apr 07; 14(4):e0275625.

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Elnahas H, Materon L, Tiwari R, Yallapu MM, Padilla V, Lozano K. Pullulan-based nanofiber membranes with antibacterial and anti-inflammatory properties for rhinosinusitis therapy. Ther Deliv. 2026 Jan; 17(1):27-38.

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da Silva RAG, Tien BYQ, Kao PHN, Antypas H, Celik C, Tan AZC, Ismail MH, Hu G, Chong KKL, Thibault G, Chen J, Kline KA. Enterococcus faecalis-derived lactic acid suppresses macrophage activation to facilitate persistent and polymicrobial wound infections. Cell Host Microbe. 2026 Feb 11; 34(2):245-262.e8.

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Rakib A, Al Mamun MA, Mandal M, Yasmen N, Ofosu-Boateng M, Collier DM, Park F, Gyamfi MA, Jiang J, Singh UP. Siglec-E deletion alters AT macrophages phenotypes, induces an inflammatory response, and adipogenesis during diet-induced obesity. Int Immunopharmacol. 2026 Jan 15; 169:115952.

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Shin HE, An S, Heckl J, Komori C, Sullivan H, Zorilla R, Yoon H, Pedro TK, Tallquist MD, Park J. PDGFRa+ fibroblast ablation exacerbates pathologic features in a model of house dust mite-induced allergenic asthma. Dis Model Mech. 2025 12 01; 18(12).

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Rosario-Rodr?guez LJ, Cantres-Rosario YM, Rodr?guez De Jes?s AE, Mera-P?rez AM, Tosado-Rodr?guez EL, Roche Lima A, Mel?ndez LM. Cannabinoid Receptor Type 2 Agonist JWH-133 Stimulates Antiviral Factors and Decreases Proviral, Inflammatory, and Neurotoxic Proteins in HIV-Infected Macrophage Secretome. Int J Mol Sci. 2025 Oct 30; 26(21).

View in: PubMed

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