"Oncostatin M" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A cytokine with both pro- and anti-inflammatory actions that depend upon the cellular microenvironment. Oncostatin M is a 28 kDa monomeric glycoprotein that is similar in structure to LEUKEMIA INHIBITORY FACTOR. Its name derives from the the observation that it inhibited the growth of tumor cells and augmented the growth of normal fibroblasts.
| Descriptor ID |
D053683
|
| MeSH Number(s) |
D12.644.276.374.562 D12.776.467.374.562 D23.529.374.562
|
| Concept/Terms |
|
Below are MeSH descriptors whose meaning is more general than "Oncostatin M".
Below are MeSH descriptors whose meaning is more specific than "Oncostatin M".
This graph shows the total number of publications written about "Oncostatin M" by people in this website by year, and whether "Oncostatin M" was a major or minor topic of these publications.
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Below are the most recent publications written about "Oncostatin M" by people in Profiles.
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Nowell MA, Richards PJ, Fielding CA, Ognjanovic S, Topley N, Williams AS, Bryant-Greenwood G, Jones SA. Regulation of pre-B cell colony-enhancing factor by STAT-3-dependent interleukin-6 trans-signaling: implications in the pathogenesis of rheumatoid arthritis. Arthritis Rheum. 2006 Jul; 54(7):2084-95.