Proto-Oncogene Proteins c-kit

"Proto-Oncogene Proteins c-kit" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure, which enables searching at various levels of specificity.

MeSH information

Definition | Details | More General Concepts | Related Concepts | More Specific Concepts

A protein-tyrosine kinase receptor that is specific for STEM CELL FACTOR. This interaction is crucial for the development of hematopoietic, gonadal, and pigment stem cells. Genetic mutations that disrupt the expression of PROTO-ONCOGENE PROTEINS C-KIT are associated with PIEBALDISM, while overexpression or constitutive activation of the c-kit protein-tyrosine kinase is associated with tumorigenesis.

Descriptor ID	D019009
MeSH Number(s)	D08.811.913.696.620.682.725.400.050 D12.776.543.750.630.124 D12.776.543.750.705.852.150.100 D12.776.543.750.750.400.200.170 D12.776.624.664.700.183
Concept/Terms	Proto-Oncogene Proteins c-kit Proto-Oncogene Proteins c-kit Proto Oncogene Proteins c kit c-kit, Proto-Oncogene Proteins Stem Cell Factor Receptor SCF Receptor p145 c-kit c-kit, p145 p145 c kit p145(c-kit) p145c-kit p145c kit CD117 Antigen Antigens, CD117 CD117 Antigens Proto-Oncogene Protein c-kit Proto Oncogene Protein c kit c-kit, Proto-Oncogene Protein c-kit Protein c kit Protein kit Proto-Oncogene Protein Proto-Oncogene Protein, kit kit Proto Oncogene Protein Receptor, Stem Cell Factor Proto-Oncogene Protein kit Proto Oncogene Protein kit c-kit Receptor c kit Receptor

Below are MeSH descriptors whose meaning is more general than "Proto-Oncogene Proteins c-kit".

Chemicals and Drugs [D]
Enzymes and Coenzymes [D08]
Enzymes [D08.811]
Transferases [D08.811.913]
Phosphotransferases [D08.811.913.696]
Phosphotransferases (Alcohol Group Acceptor) [D08.811.913.696.620]
Protein Kinases [D08.811.913.696.620.682]
Protein-Tyrosine Kinases [D08.811.913.696.620.682.725]
Receptor Protein-Tyrosine Kinases [D08.811.913.696.620.682.725.400]
Proto-Oncogene Proteins c-kit [D08.811.913.696.620.682.725.400.050]
Amino Acids, Peptides, and Proteins [D12]
Proteins [D12.776]
Membrane Proteins [D12.776.543]
Receptors, Cell Surface [D12.776.543.750]
Receptor Protein-Tyrosine Kinases [D12.776.543.750.630]
Proto-Oncogene Proteins c-kit [D12.776.543.750.630.124]
Receptors, Immunologic [D12.776.543.750.705]
Receptors, Cytokine [D12.776.543.750.705.852]
Receptors, Colony-Stimulating Factor [D12.776.543.750.705.852.150]
Proto-Oncogene Proteins c-kit [D12.776.543.750.705.852.150.100]
Receptors, Peptide [D12.776.543.750.750]
Receptors, Growth Factor [D12.776.543.750.750.400]
Receptors, Colony-Stimulating Factor [D12.776.543.750.750.400.200]
Proto-Oncogene Proteins c-kit [D12.776.543.750.750.400.200.170]
Neoplasm Proteins [D12.776.624]
Oncogene Proteins [D12.776.624.664]
Proto-Oncogene Proteins [D12.776.624.664.700]
Proto-Oncogene Proteins c-kit [D12.776.624.664.700.183]

Below are MeSH descriptors whose meaning is related to "Proto-Oncogene Proteins c-kit".

Below are MeSH descriptors whose meaning is more specific than "Proto-Oncogene Proteins c-kit".

publications

Timeline | Most Recent

This graph shows the total number of publications written about "Proto-Oncogene Proteins c-kit" by people in this website by year, and whether "Proto-Oncogene Proteins c-kit" was a major or minor topic of these publications.

Bar chart showing 9 publications over 9 distinct years, with a maximum of 1 publications in 2003 and 2005 and 2006 and 2007 and 2009 and 2010 and 2012 and 2013 and 2018

To see the data from this visualization as text, click here.

Year	Major Topic	Minor Topic	Total
2003	1	0	1
2005	1	0	1
2006	0	1	1
2007	0	1	1
2009	0	1	1
2010	0	1	1
2012	0	1	1
2013	1	0	1
2018	0	1	1

Below are the most recent publications written about "Proto-Oncogene Proteins c-kit" by people in Profiles.

Matsumoto I, Chambers JK, Nibe K, Kinoshita R, Nishimura R, Nakayama H, Uchida K. Histopathologic and Immunohistochemistry Findings in Feline Renal Cell Carcinoma. Vet Pathol. 2018 09; 55(5):663-672.

View in: PubMed
Martin H, Mali RS, Ma P, Chatterjee A, Ramdas B, Sims E, Munugalavadla V, Ghosh J, Mattingly RR, Visconte V, Tiu RV, Vlaar CP, Dharmawardhane S, Kapur R. Pak and Rac GTPases promote oncogenic KIT-induced neoplasms. J Clin Invest. 2013 Oct; 123(10):4449-63.

View in: PubMed
Hunter C, Rodriguez A, Yu JJ, Chambers J, Guentzel MN, Arulanandam B. Comparison of bone marrow-derived and mucosal mast cells in controlling intramacrophage Francisella tularensis replication. Exp Biol Med (Maywood). 2012 Jun; 237(6):617-21.

View in: PubMed
Som A, Zhu R, Guo CC, Efstathiou E, Xiao L, Pisters LL, Matin A, Tu SM. Recurrent seminomas: clinical features and biologic implications. Urol Oncol. 2012 Jul-Aug; 30(4):494-501.

View in: PubMed
Kim KI, Park J, Ahn KS, Won NH, Kim BK, Shin WG, Yoon SS, Oh JM. Molecular characterization and prognostic significance of FLT3 in CML progression. Leuk Res. 2010 Aug; 34(8):995-1001.

View in: PubMed
Zhou Q, Li Y, Nie R, Friel P, Mitchell D, Evanoff RM, Pouchnik D, Banasik B, McCarrey JR, Small C, Griswold MD. Expression of stimulated by retinoic acid gene 8 (Stra8) and maturation of murine gonocytes and spermatogonia induced by retinoic acid in vitro. Biol Reprod. 2008 Mar; 78(3):537-45.

View in: PubMed
Sun L, Hui AM, Su Q, Vortmeyer A, Kotliarov Y, Pastorino S, Passaniti A, Menon J, Walling J, Bailey R, Rosenblum M, Mikkelsen T, Fine HA. Neuronal and glioma-derived stem cell factor induces angiogenesis within the brain. Cancer Cell. 2006 Apr; 9(4):287-300.

View in: PubMed
Lee HW, Jeong YI, Choi JC, Lee MW, Choi JH, Moon KC, Koh JK. Two cases of telangiectasia macularis eruptiva perstans demonstrated by immunohistochemistry for c-kit (CD 117). J Dermatol. 2005 Oct; 32(10):817-20.

View in: PubMed
Schmandt RE, Broaddus R, Lu KH, Shvartsman H, Thornton A, Malpica A, Sun C, Bodurka DC, Gershenson DM. Expression of c-ABL, c-KIT, and platelet-derived growth factor receptor-beta in ovarian serous carcinoma and normal ovarian surface epithelium. Cancer. 2003 Aug 15; 98(4):758-64.

View in: PubMed

People

Explore

Similar Concepts

Top Journals