"Receptor, trkB" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A protein-tyrosine kinase receptor that is specific for BRAIN-DERIVED NEUROTROPHIC FACTOR; NEUROTROPHIN 3; neurotrophin 4 and neurotrophin 5. It is widely expressed in nervous tissue and plays a role in mediating the effects of neurotrophins on growth and differentiation of neuronal cells.
| Descriptor ID |
D020813
|
| MeSH Number(s) |
D08.811.913.696.620.682.725.400.700 D12.776.543.750.630.498 D12.776.543.750.750.400.550.600
|
| Concept/Terms |
Receptor, trkB- Receptor, trkB
- BDNF Receptor
- Receptor, BDNF
- trkB Receptor
- Receptor, Neurotrophic Tyrosine Kinase Type 2
- NTRK2 Receptor
- Receptor, NTRK2
- Brain Derived Neurotrophic Factor Receptor
- Neurotrophic Tyrosine Kinase Receptor Type 2
- trkB(gp145) Protein
- Neurotrophic Factor, Brain-Derived, Receptor
|
Below are MeSH descriptors whose meaning is more general than "Receptor, trkB".
Below are MeSH descriptors whose meaning is more specific than "Receptor, trkB".
This graph shows the total number of publications written about "Receptor, trkB" by people in this website by year, and whether "Receptor, trkB" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2002 | 1 | 0 | 1 |
| 2003 | 0 | 1 | 1 |
| 2005 | 1 | 2 | 3 |
| 2008 | 0 | 2 | 2 |
| 2009 | 0 | 2 | 2 |
| 2010 | 1 | 0 | 1 |
| 2012 | 1 | 0 | 1 |
| 2014 | 2 | 0 | 2 |
| 2015 | 0 | 1 | 1 |
| 2017 | 1 | 0 | 1 |
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Below are the most recent publications written about "Receptor, trkB" by people in Profiles.
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Xiao L, Chang SY, Xiong ZG, Selveraj P, Peng Loh Y. Absence of Carboxypeptidase E/Neurotrophic Factor-?1 in Knock-Out Mice Leads to Dysfunction of BDNF-TRKB Signaling in Hippocampus. J Mol Neurosci. 2017 May; 62(1):79-87.
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Williams SN, Undieh AS. Dopamine-sensitive signaling mediators modulate psychostimulant-induced ultrasonic vocalization behavior in rats. Behav Brain Res. 2016 Jan 01; 296:1-6.
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Otis JM, Fitzgerald MK, Mueller D. Infralimbic BDNF/TrkB enhancement of GluN2B currents facilitates extinction of a cocaine-conditioned place preference. J Neurosci. 2014 Apr 23; 34(17):6057-64.
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Kajiya M, Takeshita K, Kittaka M, Matsuda S, Ouhara K, Takeda K, Takata T, Kitagawa M, Fujita T, Shiba H, Kurihara H. BDNF mimetic compound LM22A-4 regulates cementoblast differentiation via the TrkB-ERK/Akt signaling cascade. Int Immunopharmacol. 2014 Apr; 19(2):245-52.
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Iuvone PM, Boatright JH, Tosini G, Ye K. N-acetylserotonin: circadian activation of the BDNF receptor and neuroprotection in the retina and brain. Adv Exp Med Biol. 2014; 801:765-71.
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Matsuda S, Fujita T, Kajiya M, Takeda K, Shiba H, Kawaguchi H, Kurihara H. Brain-derived neurotrophic factor induces migration of endothelial cells through a TrkB-ERK-integrin aV?3-FAK cascade. J Cell Physiol. 2012 May; 227(5):2123-9.
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Jang SW, Liu X, Pradoldej S, Tosini G, Chang Q, Iuvone PM, Ye K. N-acetylserotonin activates TrkB receptor in a circadian rhythm. Proc Natl Acad Sci U S A. 2010 Feb 23; 107(8):3876-81.
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Kajiya M, Shiba H, Fujita T, Takeda K, Uchida Y, Kawaguchi H, Kitagawa M, Takata T, Kurihara H. Brain-derived neurotrophic factor protects cementoblasts from serum starvation-induced cell death. J Cell Physiol. 2009 Dec; 221(3):696-706.
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Williams SN, Undieh AS. Brain-derived neurotrophic factor signaling modulates cocaine induction of reward-associated ultrasonic vocalization in rats. J Pharmacol Exp Ther. 2010 Feb; 332(2):463-8.
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Blanco RE, Soto I, Duprey-D?az M, Blagburn JM. Up-regulation of brain-derived neurotrophic factor by application of fibroblast growth factor-2 to the cut optic nerve is important for long-term survival of retinal ganglion cells. J Neurosci Res. 2008 Nov 15; 86(15):3382-92.