Protein-Tyrosine Kinases

"Protein-Tyrosine Kinases" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure, which enables searching at various levels of specificity.

MeSH information

Definition | Details | More General Concepts | Related Concepts | More Specific Concepts

Protein kinases that catalyze the PHOSPHORYLATION of TYROSINE residues in proteins with ATP or other nucleotides as phosphate donors.

Descriptor ID	D011505
MeSH Number(s)	D08.811.913.696.620.682.725
Concept/Terms	Protein-Tyrosine Kinases Protein-Tyrosine Kinases Kinases, Protein-Tyrosine Protein Tyrosine Kinases Tyrosine Kinase Kinase, Tyrosine Tyrosine Protein Kinase Kinase, Tyrosine Protein Tyrosylprotein Kinase Kinase, Tyrosylprotein Tyrosine-Specific Protein Kinase Kinase, Tyrosine-Specific Protein Protein Kinase, Tyrosine-Specific Tyrosine Specific Protein Kinase Tyrosine-Specific Protein Kinases Kinases, Tyrosine-Specific Protein Protein Kinases, Tyrosine-Specific Tyrosine Specific Protein Kinases Protein-Tyrosine Kinase Kinase, Protein-Tyrosine Protein Tyrosine Kinase Tyrosine Protein Kinases Kinases, Tyrosine Protein Protein Kinases, Tyrosine

Below are MeSH descriptors whose meaning is more general than "Protein-Tyrosine Kinases".

Chemicals and Drugs [D]
Enzymes and Coenzymes [D08]
Enzymes [D08.811]
Transferases [D08.811.913]
Phosphotransferases [D08.811.913.696]
Phosphotransferases (Alcohol Group Acceptor) [D08.811.913.696.620]
Protein Kinases [D08.811.913.696.620.682]
Protein-Tyrosine Kinases [D08.811.913.696.620.682.725]

Below are MeSH descriptors whose meaning is related to "Protein-Tyrosine Kinases".

Below are MeSH descriptors whose meaning is more specific than "Protein-Tyrosine Kinases".

publications

Timeline | Most Recent

This graph shows the total number of publications written about "Protein-Tyrosine Kinases" by people in this website by year, and whether "Protein-Tyrosine Kinases" was a major or minor topic of these publications.

Bar chart showing 107 publications over 24 distinct years, with a maximum of 12 publications in 2001

To see the data from this visualization as text, click here.

Year	Major Topic	Minor Topic	Total
1996	2	0	2
1998	2	3	5
1999	4	1	5
2000	6	4	10
2001	8	4	12
2002	5	4	9
2003	0	1	1
2004	4	7	11
2005	2	4	6
2006	2	4	6
2007	2	2	4
2008	1	0	1
2009	0	2	2
2011	1	2	3
2012	2	1	3
2013	3	0	3
2015	2	0	2
2016	1	1	2
2017	1	2	3
2019	2	1	3
2020	2	2	4
2021	2	0	2
2022	3	0	3
2024	5	0	5

Below are the most recent publications written about "Protein-Tyrosine Kinases" by people in Profiles.

Poje G, ?akic D, Marinovic M, You J, Tarpley M, Williams KP, Golub N, Dernov?ek J, Toma?ic T, Be?ic E, Rajic Z. Unveiling the antiglioblastoma potential of harmicens, harmine and ferrocene hybrids. Acta Pharm. 2024 Dec 01; 74(4):595-612.

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Peng X, Guo S, Zheng S, Hossain A, Zhang C, Mottamal M, Skripnikova E, Ma P, Martinez-Carter K, Zhang Q, Abedin F, Huckaba T, Wang G. Discovery of Oral Degraders of the ROS1 Fusion Protein with Potent Activity against Secondary Resistance Mutations. J Med Chem. 2024 Oct 24; 67(20):18098-18123.

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Yoshida S, Kawamura A, Aoki K, Wiriyasermkul P, Sugimoto S, Tomiyoshi J, Tajima A, Ishida Y, Katoh Y, Tsukada T, Tsuneoka Y, Yamada K, Nagamori S, Nakayama K, Yoshida K. Positive regulation of Hedgehog signaling via phosphorylation of GLI2/GLI3 by DYRK2 kinase. Proc Natl Acad Sci U S A. 2024 Jul 09; 121(28):e2320070121.

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Kawamura A, Yoshida S, Yoshida K. The diverse functions of DYRK2 in response to cellular stress. Histol Histopathol. 2024 Nov; 39(11):1427-1434.

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Harada E, Yoshida S, Imaizumi Y, Kawamura A, Ohtsuka T, Yoshida K. Dual-specificity tyrosine-regulated kinase 2 exerts anti-tumor effects by induction of G1 arrest in lung adenocarcinoma. Biochim Biophys Acta Gen Subj. 2024 06; 1868(6):130600.

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Hajredini F, Alphonse S, Ghose R. BY-kinases: Protein tyrosine kinases like no other. J Biol Chem. 2023 01; 299(1):102737.

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Alphonse S, Djemil I, Piserchio A, Ghose R. Structural basis for the recognition of the bacterial tyrosine kinase Wzc by its cognate tyrosine phosphatase Wzb. Proc Natl Acad Sci U S A. 2022 06 28; 119(26):e2201800119.

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Kawamura A, Yoshida S, Aoki K, Shimoyama Y, Yamada K, Yoshida K. DYRK2 maintains genome stability via neddylation of cullins in response to DNA damage. J Cell Sci. 2022 06 01; 135(11).

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Grant AH, Ayala-Marin YM, Mohl JE, Robles-Escajeda E, Rodriguez G, Dutil J, Kirken RA. The Genomic Landscape of a Restricted ALL Cohort from Patients Residing on the U.S./Mexico Border. Int J Environ Res Public Health. 2021 07 09; 18(14).

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Tarpley M, Oladapo HO, Strepay D, Caligan TB, Chdid L, Shehata H, Roques JR, Thomas R, Laudeman CP, Onyenwoke RU, Darr DB, Williams KP. Identification of harmine and ?-carboline analogs from a high-throughput screen of an approved drug collection; profiling as differential inhibitors of DYRK1A and monoamine oxidase A and for in vitro and in vivo anti-cancer studies. Eur J Pharm Sci. 2021 Jul 01; 162:105821.

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