Focal Adhesion Protein-Tyrosine Kinases

"Focal Adhesion Protein-Tyrosine Kinases" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure, which enables searching at various levels of specificity.

MeSH information

Definition | Details | More General Concepts | Related Concepts | More Specific Concepts

A family of non-receptor, PROLINE-rich protein-tyrosine kinases.

Descriptor ID	D051416
MeSH Number(s)	D08.811.913.696.620.682.725.049 D12.644.360.287 D12.776.476.287
Concept/Terms	Focal Adhesion Protein-Tyrosine Kinases Focal Adhesion Protein-Tyrosine Kinases Focal Adhesion Protein Tyrosine Kinases Focal Adhesion Protein-Tyrosine Kinase Family Focal Adhesion Protein Tyrosine Kinase Family Focal Adhesion Kinase Focal Adhesion Protein-Tyrosine Kinase

Below are MeSH descriptors whose meaning is more general than "Focal Adhesion Protein-Tyrosine Kinases".

Chemicals and Drugs [D]
Enzymes and Coenzymes [D08]
Enzymes [D08.811]
Transferases [D08.811.913]
Phosphotransferases [D08.811.913.696]
Phosphotransferases (Alcohol Group Acceptor) [D08.811.913.696.620]
Protein Kinases [D08.811.913.696.620.682]
Protein-Tyrosine Kinases [D08.811.913.696.620.682.725]
Focal Adhesion Protein-Tyrosine Kinases [D08.811.913.696.620.682.725.049]
Amino Acids, Peptides, and Proteins [D12]
Peptides [D12.644]
Intracellular Signaling Peptides and Proteins [D12.644.360]
Focal Adhesion Protein-Tyrosine Kinases [D12.644.360.287]
Proteins [D12.776]
Intracellular Signaling Peptides and Proteins [D12.776.476]
Focal Adhesion Protein-Tyrosine Kinases [D12.776.476.287]

Below are MeSH descriptors whose meaning is related to "Focal Adhesion Protein-Tyrosine Kinases".

Below are MeSH descriptors whose meaning is more specific than "Focal Adhesion Protein-Tyrosine Kinases".

Focal Adhesion Protein-Tyrosine Kinases
Focal Adhesion Kinase 1
Focal Adhesion Kinase 2

publications

Timeline | Most Recent

This graph shows the total number of publications written about "Focal Adhesion Protein-Tyrosine Kinases" by people in this website by year, and whether "Focal Adhesion Protein-Tyrosine Kinases" was a major or minor topic of these publications.

Bar chart showing 16 publications over 13 distinct years, with a maximum of 2 publications in 2005 and 2011 and 2014

To see the data from this visualization as text, click here.

Year	Major Topic	Minor Topic	Total
2002	0	1	1
2005	0	2	2
2007	1	0	1
2008	0	1	1
2009	1	0	1
2010	1	0	1
2011	2	0	2
2013	0	1	1
2014	2	0	2
2015	1	0	1
2017	1	0	1
2020	0	1	1
2024	0	1	1

Below are the most recent publications written about "Focal Adhesion Protein-Tyrosine Kinases" by people in Profiles.

Porter T, Del Valle MM, Kucheryavykh L. Ethnicity-Based Variations in Focal Adhesion Kinase Signaling in Glioblastoma Gene Expression: A Study of the Puerto Rican Hispanic Population. Int J Mol Sci. 2024 May 01; 25(9).

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Goyal V, DeVera C, Laurent V, Sellers J, Chrenek MA, Hicks D, Baba K, Iuvone PM, Tosini G. Dopamine 2 Receptor Signaling Controls the Daily Burst in Phagocytic Activity in the Mouse Retinal Pigment Epithelium. Invest Ophthalmol Vis Sci. 2020 05 11; 61(5):10.

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Kumar V, Soni UK, Maurya VK, Singh K, Jha RK. Integrin beta8 (ITGB8) activates VAV-RAC1 signaling via FAK in the acquisition of endometrial epithelial cell receptivity for blastocyst implantation. Sci Rep. 2017 05 15; 7(1):1885.

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Thanapprapasr D, Previs RA, Hu W, Ivan C, Armaiz-Pena GN, Dorniak PL, Hansen JM, Rupaimoole R, Huang J, Dalton HJ, Ali-Fehmi R, Coleman RL, Sood AK. PTEN Expression as a Predictor of Response to Focal Adhesion Kinase Inhibition in Uterine Cancer. Mol Cancer Ther. 2015 Jun; 14(6):1466-1475.

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Leung CS, Yeung TL, Yip KP, Pradeep S, Balasubramanian L, Liu J, Wong KK, Mangala LS, Armaiz-Pena GN, Lopez-Berestein G, Sood AK, Birrer MJ, Mok SC. Calcium-dependent FAK/CREB/TNNC1 signalling mediates the effect of stromal MFAP5 on ovarian cancer metastatic potential. Nat Commun. 2014 Oct 03; 5:5092.

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Stone RL, Baggerly KA, Armaiz-Pena GN, Kang Y, Sanguino AM, Thanapprapasr D, Dalton HJ, Bottsford-Miller J, Zand B, Akbani R, Diao L, Nick AM, DeGeest K, Lopez-Berestein G, Coleman RL, Lutgendorf S, Sood AK. Focal adhesion kinase: an alternative focus for anti-angiogenesis therapy in ovarian cancer. Cancer Biol Ther. 2014 Jul; 15(7):919-29.

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Morales SA, Telander DG, Leon D, Forward K, Braun J, Wadehra M, Gordon LK. Epithelial membrane protein 2 controls VEGF expression in ARPE-19 cells. Invest Ophthalmol Vis Sci. 2013 Mar 28; 54(3):2367-72.

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Fu M, Rao R, Sudhakar D, Hogue CP, Rutta Z, Morales S, Gordon LK, Braun J, Goodglick L, Wadehra M. Epithelial membrane protein-2 promotes endometrial tumor formation through activation of FAK and Src. PLoS One. 2011; 6(5):e19945.

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Shi ZD, Wang H, Tarbell JM. Heparan sulfate proteoglycans mediate interstitial flow mechanotransduction regulating MMP-13 expression and cell motility via FAK-ERK in 3D collagen. PLoS One. 2011 Jan 05; 6(1):e15956.

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Sood AK, Armaiz-Pena GN, Halder J, Nick AM, Stone RL, Hu W, Carroll AR, Spannuth WA, Deavers MT, Allen JK, Han LY, Kamat AA, Shahzad MM, McIntyre BW, Diaz-Montero CM, Jennings NB, Lin YG, Merritt WM, DeGeest K, Vivas-Mejia PE, Lopez-Berestein G, Schaller MD, Cole SW, Lutgendorf SK. Adrenergic modulation of focal adhesion kinase protects human ovarian cancer cells from anoikis. J Clin Invest. 2010 May; 120(5):1515-23.

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