G-Protein-Coupled Receptor Kinases
"G-Protein-Coupled Receptor Kinases" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A family of serine-threonine kinases that are specific for G-PROTEIN-COUPLED RECEPTORS. They are regulatory proteins that play a role in G-protein-coupled receptor densensitization.
| Descriptor ID |
D054768
|
| MeSH Number(s) |
D08.811.913.696.620.682.700.364 D12.644.360.293 D12.776.476.293
|
| Concept/Terms |
G-Protein-Coupled Receptor Kinases- G-Protein-Coupled Receptor Kinases
- G Protein Coupled Receptor Kinases
- Kinases, G-Protein-Coupled Receptor
- Receptor Kinases, G-Protein-Coupled
|
Below are MeSH descriptors whose meaning is more general than "G-Protein-Coupled Receptor Kinases".
Below are MeSH descriptors whose meaning is more specific than "G-Protein-Coupled Receptor Kinases".
This graph shows the total number of publications written about "G-Protein-Coupled Receptor Kinases" by people in this website by year, and whether "G-Protein-Coupled Receptor Kinases" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2002 | 0 | 1 | 1 |
| 2012 | 1 | 0 | 1 |
| 2013 | 1 | 0 | 1 |
| 2014 | 1 | 0 | 1 |
| 2016 | 0 | 1 | 1 |
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Below are the most recent publications written about "G-Protein-Coupled Receptor Kinases" by people in Profiles.
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Delgado-Peraza F, Ahn KH, Nogueras-Ortiz C, Mungrue IN, Mackie K, Kendall DA, Yudowski GA. Mechanisms of Biased ?-Arrestin-Mediated Signaling Downstream from the Cannabinoid 1 Receptor. Mol Pharmacol. 2016 06; 89(6):618-29.
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Singh V, Raghuwanshi SK, Smith N, Rivers EJ, Richardson RM. G Protein-coupled receptor kinase-6 interacts with activator of G protein signaling-3 to regulate CXCR2-mediated cellular functions. J Immunol. 2014 Mar 01; 192(5):2186-94.
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Raghuwanshi SK, Smith N, Rivers EJ, Thomas AJ, Sutton N, Hu Y, Mukhopadhyay S, Chen XL, Leung T, Richardson RM. G protein-coupled receptor kinase 6 deficiency promotes angiogenesis, tumor progression, and metastasis. J Immunol. 2013 May 15; 190(10):5329-36.
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Raghuwanshi SK, Su Y, Singh V, Haynes K, Richmond A, Richardson RM. The chemokine receptors CXCR1 and CXCR2 couple to distinct G protein-coupled receptor kinases to mediate and regulate leukocyte functions. J Immunol. 2012 Sep 15; 189(6):2824-32.
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Fong AM, Premont RT, Richardson RM, Yu YR, Lefkowitz RJ, Patel DD. Defective lymphocyte chemotaxis in beta-arrestin2- and GRK6-deficient mice. Proc Natl Acad Sci U S A. 2002 May 28; 99(11):7478-83.