Adaptor Proteins, Signal Transducing

"Adaptor Proteins, Signal Transducing" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure, which enables searching at various levels of specificity.

MeSH information

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A broad category of carrier proteins that play a role in SIGNAL TRANSDUCTION. They generally contain several modular domains, each of which having its own binding activity, and act by forming complexes with other intracellular-signaling molecules. Signal-transducing adaptor proteins lack enzyme activity, however their activity can be modulated by other signal-transducing enzymes

Descriptor ID	D048868
MeSH Number(s)	D12.644.360.024 D12.776.157.057 D12.776.476.024
Concept/Terms	Adaptor Proteins, Signal Transducing Adaptor Proteins, Signal Transducing Signal Transducing Adaptor Proteins

Below are MeSH descriptors whose meaning is more general than "Adaptor Proteins, Signal Transducing".

Chemicals and Drugs [D]
Amino Acids, Peptides, and Proteins [D12]
Peptides [D12.644]
Intracellular Signaling Peptides and Proteins [D12.644.360]
Adaptor Proteins, Signal Transducing [D12.644.360.024]
Proteins [D12.776]
Carrier Proteins [D12.776.157]
Adaptor Proteins, Signal Transducing [D12.776.157.057]
Intracellular Signaling Peptides and Proteins [D12.776.476]
Adaptor Proteins, Signal Transducing [D12.776.476.024]

Below are MeSH descriptors whose meaning is related to "Adaptor Proteins, Signal Transducing".

Below are MeSH descriptors whose meaning is more specific than "Adaptor Proteins, Signal Transducing".

publications

Timeline | Most Recent

This graph shows the total number of publications written about "Adaptor Proteins, Signal Transducing" by people in this website by year, and whether "Adaptor Proteins, Signal Transducing" was a major or minor topic of these publications.

Bar chart showing 174 publications over 29 distinct years, with a maximum of 17 publications in 2011

To see the data from this visualization as text, click here.

Year	Major Topic	Minor Topic	Total
1998	2	0	2
1999	1	0	1
2000	1	1	2
2001	1	2	3
2002	2	2	4
2003	4	4	8
2004	1	2	3
2005	3	6	9
2006	1	1	2
2007	3	5	8
2008	5	6	11
2009	5	1	6
2010	4	6	10
2011	11	6	17
2012	5	6	11
2013	4	6	10
2014	4	5	9
2015	3	4	7
2016	3	5	8
2017	4	1	5
2018	3	2	5
2019	6	2	8
2020	3	3	6
2021	1	4	5
2022	2	2	4
2023	0	3	3
2024	1	1	2
2025	2	2	4
2026	1	0	1

Below are the most recent publications written about "Adaptor Proteins, Signal Transducing" by people in Profiles.

Al-Mathkour MM, Dwead AM, Khazaw K, Cinar B. The YAP1 and EPHA3 receptor tyrosine kinase axis regulates cellular plasticity and treatment response. Cell Signal. 2026 May; 141:112368.

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Mahbub M, Saha B, Goss DJ. 4E-BP1 differentially regulates translation of a subset of human mRNAs. J Biol Chem. 2026 01; 302(1):110976.

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Mallick D, Ghosh I, Mondal T, Mondal S, Mukhopadhyay R, Joseph J, Ghosh S, Jana SS. Cellular elasticity drives mechano-adaptation against fluid shear stress. J Cell Sci. 2025 Nov 01; 138(21).

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Ochoa PT, Sanchez-Hernandez ES, Duran AM, Cheng KW, Philip J, Suzuki T, Unternaehrer JJ, Dutil J, Das B, Ganguly R, Baca Y, de Semir D, Wang C, Kremsky I, Casiano CA. The GR-LEDGF/p75-HSP27 Axis Contributes to Cross-Resistance Between Enzalutamide and Docetaxel in Prostate Cancer. Cells. 2025 Oct 09; 14(19).

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Ellison V, Polotskaia A, Xiao G, Leybengrub P, Lee R, Qiu W, Hendrickson RC, Hu W, Bargonetti J. A cancer persistent DNA repair circuit driven by MDM2, MDM4 (MDMX), and mutant p53 for recruitment of MDC1 and 53BP1 on chromatin. Nucleic Acids Res. 2025 Jul 08; 53(13).

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Pave?kovic M, De-Paula RB, Ojelade SA, Tantry EK, Kochukov MY, Bao S, Veeraragavan S, Garza AR, Srivastava S, Song SY, Fujita M, Duong DM, Bennett DA, De Jager PL, Seyfried NT, Dickinson ME, Heaney JD, Arenkiel BR, Shulman JM. Alzheimer's disease risk gene CD2AP is a dose-sensitive determinant of synaptic structure and plasticity. Hum Mol Genet. 2024 10 07; 33(20):1815-1832.

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Zhu N, Rogers WE, Heidary DK, Huxford T. Structural and biochemical analyses of the nuclear I?B? protein in complex with the NF-?B p50 homodimer. Genes Dev. 2024 07 19; 38(11-12):528-535.

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Alimardan Z, Abbasi M, Hasanzadeh F, Aghaei M, Khodarahmi G, Kashfi K. Heat shock proteins and cancer: The FoxM1 connection. Biochem Pharmacol. 2023 05; 211:115505.

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Zhang X, Xing M, Ma Y, Zhang Z, Qiu C, Wang X, Zhao Z, Ji Z, Zhang JY. Oridonin Induces Apoptosis in Esophageal Squamous Cell Carcinoma by Inhibiting Cytoskeletal Protein LASP1 and PDLIM1. Molecules. 2023 Jan 13; 28(2).

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Earley EJ, Kelly S, Fang F, Alencar CS, Rodrigues DOW, Soares Cruz DT, Flanagan JM, Ware RE, Zhang X, Gordeuk V, Gladwin M, Zhang Y, Nouraie M, Nekhai S, Sabino E, Custer B, Dinardo C, Page GP. Genome-wide association study of early ischaemic stroke risk in Brazilian individuals with sickle cell disease implicates ADAMTS2 and CDK18 and uncovers novel loci. Br J Haematol. 2023 04; 201(2):343-352.

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