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Joshua M. Shulman

TitleInstructor
Faculty RankInstructor
InstitutionCharles R. Drew University of Medicine and Science
DepartmentGeneral Studies
Address1731 E. 120th Street
1731 E. 120th Street
Los Angeles CA 90059
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    Collapse Research 
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    K08AG034290     (SHULMAN, JOSHUA M.)Aug 15, 2009 - Jul 31, 2014
    NIH
    Exploring the Genetics of Alzheimer's Disease in Humans and Drosophila
    Role: Principal Investigator
    R21NS089854     (SHULMAN, JOSHUA M.)Sep 1, 2014 - Aug 31, 2017
    NIH
    Functional Validation of Parkinsons Disease Susceptibility Genes in Drosophila
    Role: Principal Investigator
    R01AG050631     (SHULMAN, JOSHUA M)May 1, 2016 - Apr 30, 2021
    NIH
    Functional Validation of the CD2AP Susceptibility Network in Alzheimer's Disease
    Role: Principal Investigator
    R01AG053960     (SHULMAN, JOSHUA M)Sep 15, 2016 - Apr 30, 2021
    NIH
    Tau-Spliceosome Interactions in Alzheimer's Disease
    Role: Principal Investigator
    R01AG057339     (BOTAS, JUAN)Sep 15, 2017 - May 31, 2022
    NIH
    Functional Dissection of Alzheimer's Disease Networks in Drosophila: from Association to Causal Modulators of Age-Dependent Neurodegeration
    Role: Co-Principal Investigator
    U01AG061357     (LEVEY, ALLAN I ;SEYFRIED, NICHOLAS THOMAS;SHULMAN, JOSHUA M)Sep 30, 2018 - Aug 31, 2023
    NIH
    AMP-AD Brain Proteomic Network Enhancement, Validation, and Translation into CSF Biomarkers
    Role: Co-Principal Investigator
    R21AG068961     (SHULMAN, JOSHUA M)Aug 1, 2020 - Apr 30, 2022
    NIH
    Metabolo-Genetic Dissection of GBA and Lysosomal Genes in Parkinson's Disease and Lewy Body Dementia
    Role: Principal Investigator
    RF1AG070436     (SHAW, PAUL J)Apr 1, 2021 - Mar 31, 2024
    NIH
    Bidirectional interactions between sleep and Alzheimer's disease: Functional dissection of the brain transcriptome in humans and Drosophila
    Role: Co-Principal Investigator
    R01AG070436     (SHAW, PAUL J)Apr 1, 2021 - Mar 31, 2026
    NIH
    Bidirectional interactions between sleep and Alzheimer's disease: Functional dissection of the brain transcriptome in humans and Drosophila
    Role: Co-Principal Investigator
    U01AG072439     (SHULMAN, JOSHUA M)Jul 1, 2021 - Jun 30, 2026
    NIH
    Functional Genomic Dissection of Alzheimer's Disease in Humans and Drosophila Models
    Role: Principal Investigator

    Collapse Bibliographic 
    Collapse selected publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
    Newest   |   Oldest   |   Most Cited   |   Most Discussed   |   Timeline   |   Field Summary   |   Plain Text
    PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Pave?kovic M, De-Paula RB, Ojelade SA, Tantry EK, Kochukov MY, Bao S, Veeraragavan S, Garza AR, Srivastava S, Song SY, Fujita M, Duong DM, Bennett DA, De Jager PL, Seyfried NT, Dickinson ME, Heaney JD, Arenkiel BR, Shulman JM. Alzheimer's disease risk gene CD2AP is a dose-sensitive determinant of synaptic structure and plasticity. Hum Mol Genet. 2024 10 07; 33(20):1815-1832. PMID: 39146503.
      Citations: 1     Fields:    Translation:HumansAnimalsCells
    2. Atalla A, Shulman J, Rose J, Lynch M. Trends in chlorine and chloramine gas exposures reported to United States poison centers. Clin Toxicol (Phila). 2024 Sep; 62(9):589-595. PMID: 39263698.
      Citations:    Fields:    Translation:HumansPHPublic Health
    3. Levine M, Culbreth R, Amaducci A, Calello DP, Shulman J, Judge B, Love J, Hughes A, Schwarz ES, Carpenter J, Wax P, Aldy K, Krotulski AJ, Logan BK, Buchanan J, Brent J, Meaden CW, Hendrickson RG, Abston S, Li S, Campleman S, Manini AF. Prevalence and predictors of HIV among patients presenting to US emergency departments with opioid overdose. Drug Alcohol Depend. 2024 Nov 01; 264:112423. PMID: 39270332.
      Citations:    Fields:    Translation:Humans
    4. Goodman LD, Ralhan I, Li X, Lu S, Moulton MJ, Park YJ, Zhao P, Kanca O, Ghaderpour Taleghani ZS, Jacquemyn J, Shulman JM, Ando K, Sun K, Ioannou MS, Bellen HJ. Tau is required for glial lipid droplet formation and resistance to neuronal oxidative stress. Nat Neurosci. 2024 Oct; 27(10):1918-1933. PMID: 39187706.
      Citations:    Fields:    Translation:HumansAnimalsCells
    5. Shastry S, Lin J, Aldy K, Brent J, Wax P, Krotulski A, Campleman S, Li S, Meyn A, Abston S, Logan B, Amaducci A, Judge B, Levine M, Calello D, Shulman J, Hughes A, Culbreth R, Schwarz E, Manini AF. Heroin or fentanyl: Prevalence of confirmed fentanyl in ED patients with suspected heroin overdose. J Am Coll Emerg Physicians Open. 2024 Aug; 5(4):e13235. PMID: 39161754.
      Citations:    
    6. Buchman AS, Yu L, Oveisgharan S, Zammit AR, Wang T, Shulman JM, VanderHorst V, Nag S, Bennett DA. Parkinson's Disease and Other Alzheimer's Disease and Related Dementia Pathologies and the Progression of Parkinsonism in Older Adults. J Alzheimers Dis. 2024; 100(s1):S197-S209. PMID: 39121125.
      Citations:    Fields:    Translation:Humans
    7. Smith HS, Robinson JO, Levchenko A, Pereira S, Pascual B, Bradbury K, Arbones V, Fong J, Shulman JM, McGuire AL, Masdeu J. Research Participants' Perspectives on Precision Diagnostics for Alzheimer's Disease. J Alzheimers Dis. 2024; 97(3):1261-1274. PMID: 38250770.
      Citations: 1     Fields:    Translation:Humans
    8. Croskey A, Trautman W, Barton D, Ratay MK, Shulman J. Ocular injury from saltwater coral palytoxin. Am J Emerg Med. 2024 01; 75:197.e1-197.e3. PMID: 37945412.
      Citations:    Fields:    Translation:HumansAnimals
    9. Wu T, Deger JM, Ye H, Guo C, Dhindsa J, Pekarek BT, Al-Ouran R, Liu Z, Al-Ramahi I, Botas J, Shulman JM. Tau polarizes an aging transcriptional signature to excitatory neurons and glia. Elife. 2023 May 23; 12. PMID: 37219079.
      Citations: 3     Fields:    Translation:HumansAnimalsCells
    10. Yu M, Ye H, De-Paula RB, Mangleburg CG, Wu T, Lee TV, Li Y, Duong D, Phillips B, Cruchaga C, Allen GI, Seyfried NT, Al-Ramahi I, Botas J, Shulman JM. Functional screening of lysosomal storage disorder genes identifies modifiers of alpha-synuclein neurotoxicity. PLoS Genet. 2023 05; 19(5):e1010760. PMID: 37200393.
      Citations: 3     Fields:    Translation:HumansAnimalsCells
    11. Khetarpal SK, Rengasamy M, Adebiyi O, Hsiung K, Wong S, Shulman J, Pizon A. Risk Factors and Clinical Correlates of Pediatric Serotonin Syndrome in Hospitalized Suicide Attempters. J Pediatr X. 2023; 9:100086. PMID: 37334280.
      Citations:    
    12. Love JS, Levine M, Aldy K, Brent J, Krotulski AJ, Logan BK, Vargas-Torres C, Walton SE, Amaducci A, Calello D, Hendrickson R, Hughes A, Kurt A, Judge B, Pizon A, Schwarz E, Shulman J, Wiegan T, Wax P, Manini AF. Opioid overdoses involving xylazine in emergency department patients: a multicenter study. Clin Toxicol (Phila). 2023 03; 61(3):173-180. PMID: 37014353.
      Citations: 19     Fields:    Translation:Humans
    13. Li J, Amoh BK, McCormick E, Tarkunde A, Zhu KF, Perez A, Mair M, Moore J, Shulman JM, Al-Ramahi I, Botas J. Integration of transcriptome-wide association study with neuronal dysfunction assays provides functional genomics evidence for Parkinson's disease genes. Hum Mol Genet. 2023 01 27; 32(4):685-695. PMID: 36173927.
      Citations: 3     Fields:    Translation:AnimalsCells
    14. Ye H, Robak LA, Yu M, Cykowski M, Shulman JM. Genetics and Pathogenesis of Parkinson's Syndrome. Annu Rev Pathol. 2023 01 24; 18:95-121. PMID: 36100231.
      Citations: 78     Fields:    Translation:HumansCells
    15. Ye F, Funk Q, Rockers E, Shulman JM, Masdeu JC, Pascual B. In Alzheimer-prone brain regions, metabolism and risk-gene expression are strongly correlated. Brain Commun. 2022; 4(5):fcac216. PMID: 36092303.
      Citations:    
    16. Lagisetty Y, Bourquard T, Al-Ramahi I, Mangleburg CG, Mota S, Soleimani S, Shulman JM, Botas J, Lee K, Lichtarge O. Identification of risk genes for Alzheimer's disease by gene embedding. Cell Genom. 2022 Sep 14; 2(9). PMID: 36268052.
      Citations: 10     Fields:    
    17. Hill EJ, Robak LA, Al-Ouran R, Deger J, Fong JC, Vandeventer PJ, Schulman E, Rao S, Saade H, Savitt JM, von Coelln R, Desai N, Doddapaneni H, Salvi S, Dugan-Perez S, Muzny DM, McGuire AL, Liu Z, Gibbs RA, Shaw C, Jankovic J, Shulman LM, Shulman JM. Genome Sequencing in the Parkinson Disease Clinic. Neurol Genet. 2022 Aug; 8(4):e200002. PMID: 35747619.
      Citations:    
    18. Bazargan-Hejazi S, Shirazi A, Wang A, Shlobin NA, Karunungan K, Shulman J, Marzio R, Ebrahim G, Shay W, Slavin S. Contribution of a positive psychology-based conceptual framework in reducing physician burnout and improving well-being: a systematic review. BMC Med Educ. 2021 Nov 25; 21(1):593. PMID: 34823509.
      Citations: 10     Fields:    Translation:Humans
    19. Bailey M, Shulman LM, Ryan D, Ouyang B, Shulman JM, Buchman AS, Bennett DA, Barnes LL, Hall DA. Frequency of Parkinsonism and Parkinson Disease in African Americans in the Chicago Community. J Gerontol A Biol Sci Med Sci. 2021 06 14; 76(7):1340-1345. PMID: 33631006.
      Citations: 3     Fields:    Translation:Humans
    20. Abreha MH, Ojelade S, Dammer EB, McEachin ZT, Duong DM, Gearing M, Bassell GJ, Lah JJ, Levey AI, Shulman JM, Seyfried NT. TBK1 interacts with tau and enhances neurodegeneration in tauopathy. J Biol Chem. 2021 Jan-Jun; 296:100760. PMID: 33965374.
      Citations: 11     Fields:    Translation:HumansAnimalsCells
    21. Petyuk VA, Yu L, Olson HM, Yu F, Clair G, Qian WJ, Shulman JM, Bennett DA. Proteomic Profiling of the Substantia Nigra to Identify Determinants of Lewy Body Pathology and Dopaminergic Neuronal Loss. J Proteome Res. 2021 05 07; 20(5):2266-2282. PMID: 33900085.
      Citations: 9     Fields:    Translation:HumansCells
    22. Guo Q, Dammer EB, Zhou M, Kundinger SR, Gearing M, Lah JJ, Levey AI, Shulman JM, Seyfried NT. Targeted Quantification of Detergent-Insoluble RNA-Binding Proteins in Human Brain Reveals Stage and Disease Specific Co-aggregation in Alzheimer's Disease. Front Mol Neurosci. 2021; 14:623659. PMID: 33815056.
      Citations:    
    23. Hill EJ, Mangleburg CG, Alfradique-Dunham I, Ripperger B, Stillwell A, Saade H, Rao S, Fagbongbe O, von Coelln R, Tarakad A, Hunter C, Dawe RJ, Jankovic J, Shulman LM, Buchman AS, Shulman JM. Quantitative mobility measures complement the MDS-UPDRS for characterization of Parkinson's disease heterogeneity. Parkinsonism Relat Disord. 2021 03; 84:105-111. PMID: 33607526.
      Citations: 8     Fields:    Translation:Humans
    24. Alfradique-Dunham I, Al-Ouran R, von Coelln R, Blauwendraat C, Hill E, Luo L, Stillwell A, Young E, Kaw A, Tan M, Liao C, Hernandez D, Pihlstrom L, Grosset D, Shulman LM, Liu Z, Rouleau GA, Nalls M, Singleton AB, Morris H, Jankovic J, Shulman JM. Genome-Wide Association Study Meta-Analysis for Parkinson Disease Motor Subtypes. Neurol Genet. 2021 Apr; 7(2):e557. PMID: 33987465.
      Citations:    
    25. Yao T, Sweeney E, Nagorski J, Shulman JM, Allen GI. Quantifying cognitive resilience in Alzheimer's Disease: The Alzheimer's Disease Cognitive Resilience Score. PLoS One. 2020; 15(11):e0241707. PMID: 33152028.
      Citations: 11     Fields:    Translation:Humans
    26. Mangleburg CG, Wu T, Yalamanchili HK, Guo C, Hsieh YC, Duong DM, Dammer EB, De Jager PL, Seyfried NT, Liu Z, Shulman JM. Integrated analysis of the aging brain transcriptome and proteome in tauopathy. Mol Neurodegener. 2020 09 29; 15(1):56. PMID: 32993812.
      Citations: 13     Fields:    Translation:HumansAnimalsCells
    27. Robak LA, Du R, Yuan B, Gu S, Alfradique-Dunham I, Kondapalli V, Hinojosa E, Stillwell A, Young E, Zhang C, Song X, Du H, Gambin T, Jhangiani SN, Coban Akdemir Z, Muzny DM, Tejomurtula A, Ross OA, Shaw C, Jankovic J, Bi W, Posey JE, Lupski JR, Shulman JM. Integrated sequencing and array comparative genomic hybridization in familial Parkinson disease. Neurol Genet. 2020 Oct; 6(5):e498. PMID: 32802956.
      Citations:    
    28. Wan YW, Al-Ouran R, Mangleburg CG, Perumal TM, Lee TV, Allison K, Swarup V, Funk CC, Gaiteri C, Allen M, Wang M, Neuner SM, Kaczorowski CC, Philip VM, Howell GR, Martini-Stoica H, Zheng H, Mei H, Zhong X, Kim JW, Dawson VL, Dawson TM, Pao PC, Tsai LH, Haure-Mirande JV, Ehrlich ME, Chakrabarty P, Levites Y, Wang X, Dammer EB, Srivastava G, Mukherjee S, Sieberts SK, Omberg L, Dang KD, Eddy JA, Snyder P, Chae Y, Amberkar S, Wei W, Hide W, Preuss C, Ergun A, Ebert PJ, Airey DC, Mostafavi S, Yu L, Klein HU, Carter GW, Collier DA, Golde TE, Levey AI, Bennett DA, Estrada K, Townsend TM, Zhang B, Schadt E, De Jager PL, Price ND, Ertekin-Taner N, Liu Z, Shulman JM, Mangravite LM, Logsdon BA. Meta-Analysis of the Alzheimer's Disease Human Brain Transcriptome and Functional Dissection in Mouse Models. Cell Rep. 2020 07 14; 32(2):107908. PMID: 32668255.
      Citations: 141     Fields:    Translation:HumansAnimalsCells
    29. Ye H, Ojelade SA, Li-Kroeger D, Zuo Z, Wang L, Li Y, Gu JY, Tepass U, Rodal AA, Bellen HJ, Shulman JM. Retromer subunit, VPS29, regulates synaptic transmission and is required for endolysosomal function in the aging brain. Elife. 2020 04 14; 9. PMID: 32286230.
      Citations: 24     Fields:    Translation:AnimalsCells
    30. Johnson ECB, Dammer EB, Duong DM, Ping L, Zhou M, Yin L, Higginbotham LA, Guajardo A, White B, Troncoso JC, Thambisetty M, Montine TJ, Lee EB, Trojanowski JQ, Beach TG, Reiman EM, Haroutunian V, Wang M, Schadt E, Zhang B, Dickson DW, Ertekin-Taner N, Golde TE, Petyuk VA, De Jager PL, Bennett DA, Wingo TS, Rangaraju S, Hajjar I, Shulman JM, Lah JJ, Levey AI, Seyfried NT. Large-scale proteomic analysis of Alzheimer's disease brain and cerebrospinal fluid reveals early changes in energy metabolism associated with microglia and astrocyte activation. Nat Med. 2020 05; 26(5):769-780. PMID: 32284590.
      Citations: 400     Fields:    Translation:HumansAnimalsCells
    31. Campleman SL, Brent J, Pizon AF, Shulman J, Wax P, Manini AF. Drug-specific risk of severe QT prolongation following acute drug overdose. Clin Toxicol (Phila). 2020 12; 58(12):1326-1334. PMID: 32252558.
      Citations: 11     Fields:    Translation:Humans
    32. Blauwendraat C, Reed X, Krohn L, Heilbron K, Bandres-Ciga S, Tan M, Gibbs JR, Hernandez DG, Kumaran R, Langston R, Bonet-Ponce L, Alcalay RN, Hassin-Baer S, Greenbaum L, Iwaki H, Leonard HL, Grenn FP, Ruskey JA, Sabir M, Ahmed S, Makarious MB, Pihlstr?m L, Toft M, van Hilten JJ, Marinus J, Schulte C, Brockmann K, Sharma M, Siitonen A, Majamaa K, Eerola-Rautio J, Tienari PJ, Pantelyat A, Hillis AE, Dawson TM, Rosenthal LS, Albert MS, Resnick SM, Ferrucci L, Morris CM, Pletnikova O, Troncoso J, Grosset D, Lesage S, Corvol JC, Brice A, Noyce AJ, Masliah E, Wood N, Hardy J, Shulman LM, Jankovic J, Shulman JM, Heutink P, Gasser T, Cannon P, Scholz SW, Morris H, Cookson MR, Nalls MA, Gan-Or Z, Singleton AB. Genetic modifiers of risk and age at onset in GBA associated Parkinson's disease and Lewy body dementia. Brain. 2020 01 01; 143(1):234-248. PMID: 31755958.
      Citations: 104     Fields:    Translation:HumansCells
    33. Reynolds K, Kaufman R, Korenoski A, Fennimore L, Shulman J, Lynch M. Trends in gabapentin and baclofen exposures reported to U.S. poison centers. Clin Toxicol (Phila). 2020 07; 58(7):763-772. PMID: 31786961.
      Citations: 8     Fields:    Translation:Humans
    34. Nalls MA, Blauwendraat C, Vallerga CL, Heilbron K, Bandres-Ciga S, Chang D, Tan M, Kia DA, Noyce AJ, Xue A, Bras J, Young E, von Coelln R, Sim?n-S?nchez J, Schulte C, Sharma M, Krohn L, Pihlstr?m L, Siitonen A, Iwaki H, Leonard H, Faghri F, Gibbs JR, Hernandez DG, Scholz SW, Botia JA, Martinez M, Corvol JC, Lesage S, Jankovic J, Shulman LM, Sutherland M, Tienari P, Majamaa K, Toft M, Andreassen OA, Bangale T, Brice A, Yang J, Gan-Or Z, Gasser T, Heutink P, Shulman JM, Wood NW, Hinds DA, Hardy JA, Morris HR, Gratten J, Visscher PM, Graham RR, Singleton AB. Identification of novel risk loci, causal insights, and heritable risk for Parkinson's disease: a meta-analysis of genome-wide association studies. Lancet Neurol. 2019 12; 18(12):1091-1102. PMID: 31701892.
      Citations: 954     Fields:    Translation:Humans
    35. Satizabal CL, Adams HHH, Hibar DP, White CC, Knol MJ, Stein JL, Scholz M, Sargurupremraj M, Jahanshad N, Roshchupkin GV, Smith AV, Bis JC, Jian X, Luciano M, Hofer E, Teumer A, van der Lee SJ, Yang J, Yanek LR, Lee TV, Li S, Hu Y, Koh JY, Eicher JD, Desrivi?res S, Arias-Vasquez A, Chauhan G, Athanasiu L, Renter?a ME, Kim S, Hoehn D, Armstrong NJ, Chen Q, Holmes AJ, den Braber A, Kloszewska I, Andersson M, Espeseth T, Grimm O, Abramovic L, Alhusaini S, Milaneschi Y, Papmeyer M, Axelsson T, Ehrlich S, Roiz-Santia?ez R, Kraemer B, H?berg AK, Jones HJ, Pike GB, Stein DJ, Stevens A, Bralten J, Vernooij MW, Harris TB, Filippi I, Witte AV, Guadalupe T, Wittfeld K, Mosley TH, Becker JT, Doan NT, Hagenaars SP, Saba Y, Cuellar-Partida G, Amin N, Hilal S, Nho K, Mirza-Schreiber N, Arfanakis K, Becker DM, Ames D, Goldman AL, Lee PH, Boomsma DI, Lovestone S, Giddaluru S, Le Hellard S, Mattheisen M, Bohlken MM, Kasperaviciute D, Schmaal L, Lawrie SM, Agartz I, Walton E, Tordesillas-Gutierrez D, Davies GE, Shin J, Ipser JC, Vinke LN, Hoogman M, Jia T, Burkhardt R, Klein M, Crivello F, Janowitz D, Carmichael O, Haukvik UK, Aribisala BS, Schmidt H, Strike LT, Cheng CY, Risacher SL, P?tz B, Fleischman DA, Assareh AA, Mattay VS, Buckner RL, Mecocci P, Dale AM, Cichon S, Boks MP, Matarin M, Penninx BWJH, Calhoun VD, Chakravarty MM, Marquand AF, Macare C, Kharabian Masouleh S, Oosterlaan J, Amouyel P, Hegenscheid K, Rotter JI, Schork AJ, Liewald DCM, de Zubicaray GI, Wong TY, Shen L, S?mann PG, Brodaty H, Roffman JL, de Geus EJC, Tsolaki M, Erk S, van Eijk KR, Cavalleri GL, van der Wee NJA, McIntosh AM, Gollub RL, Bulayeva KB, Bernard M, Richards JS, Himali JJ, Loeffler M, Rommelse N, Hoffmann W, Westlye LT, Vald?s Hern?ndez MC, Hansell NK, van Erp TGM, Wolf C, Kwok JBJ, Vellas B, Heinz A, Olde Loohuis LM, Delanty N, Ho BC, Ching CRK, Shumskaya E, Singh B, Hofman A, van der Meer D, Homuth G, Psaty BM, Bastin ME, Montgomery GW, Foroud TM, Reppermund S, Hottenga JJ, Simmons A, Meyer-Lindenberg A, Cahn W, Whelan CD, van Donkelaar MMJ, Yang Q, Hosten N, Green RC, Thalamuthu A, Mohnke S, Hulshoff Pol HE, Lin H, Jack CR, Schofield PR, M?hleisen TW, Maillard P, Potkin SG, Wen W, Fletcher E, Toga AW, Gruber O, Huentelman M, Davey Smith G, Launer LJ, Nyberg L, J?nsson EG, Crespo-Facorro B, Koen N, Greve DN, Uitterlinden AG, Weinberger DR, Steen VM, Fedko IO, Groenewold NA, Niessen WJ, Toro R, Tzourio C, Longstreth WT, Ikram MK, Smoller JW, van Tol MJ, Sussmann JE, Paus T, Lema?tre H, Schroeter ML, Mazoyer B, Andreassen OA, Holsboer F, Depondt C, Veltman DJ, Turner JA, Pausova Z, Schumann G, van Rooij D, Djurovic S, Deary IJ, McMahon KL, M?ller-Myhsok B, Brouwer RM, Soininen H, Pandolfo M, Wassink TH, Cheung JW, Wolfers T, Martinot JL, Zwiers MP, Nauck M, Melle I, Martin NG, Kanai R, Westman E, Kahn RS, Sisodiya SM, White T, Saremi A, van Bokhoven H, Brunner HG, V?lzke H, Wright MJ, van 't Ent D, N?then MM, Ophoff RA, Buitelaar JK, Fern?ndez G, Sachdev PS, Rietschel M, van Haren NEM, Fisher SE, Beiser AS, Francks C, Saykin AJ, Mather KA, Romanczuk-Seiferth N, Hartman CA, DeStefano AL, Heslenfeld DJ, Weiner MW, Walter H, Hoekstra PJ, Nyquist PA, Franke B, Bennett DA, Grabe HJ, Johnson AD, Chen C, van Duijn CM, Lopez OL, Fornage M, Wardlaw JM, Schmidt R, DeCarli C, De Jager PL, Villringer A, Debette S, Gudnason V, Medland SE, Shulman JM, Thompson PM, Seshadri S, Ikram MA. Genetic architecture of subcortical brain structures in 38,851 individuals. Nat Genet. 2019 11; 51(11):1624-1636. PMID: 31636452.
      Citations: 124     Fields:    Translation:HumansAnimals
    36. Hsieh YC, Guo C, Yalamanchili HK, Abreha M, Al-Ouran R, Li Y, Dammer EB, Lah JJ, Levey AI, Bennett DA, De Jager PL, Seyfried NT, Liu Z, Shulman JM. Tau-Mediated Disruption of the Spliceosome Triggers Cryptic RNA Splicing and Neurodegeneration in Alzheimer's Disease. Cell Rep. 2019 10 08; 29(2):301-316.e10. PMID: 31597093.
      Citations: 77     Fields:    Translation:HumansAnimalsCells
    37. Al-Ouran R, Wan YW, Mangleburg CG, Lee TV, Allison K, Shulman JM, Liu Z. A Portal to Visualize Transcriptome Profiles in Mouse Models of Neurological Disorders. Genes (Basel). 2019 09 26; 10(10). PMID: 31561642.
      Citations: 5     Fields:    Translation:AnimalsCells
    38. Ojelade SA, Lee TV, Giagtzoglou N, Yu L, Ugur B, Li Y, Duraine L, Zuo Z, Petyuk V, De Jager PL, Bennett DA, Arenkiel BR, Bellen HJ, Shulman JM. cindr, the Drosophila Homolog of the CD2AP Alzheimer's Disease Risk Gene, Is Required for Synaptic Transmission and Proteostasis. Cell Rep. 2019 08 13; 28(7):1799-1813.e5. PMID: 31412248.
      Citations: 21     Fields:    Translation:HumansAnimalsCells
    39. von Coelln R, Dawe RJ, Leurgans SE, Curran TA, Truty T, Yu L, Barnes LL, Shulman JM, Shulman LM, Bennett DA, Hausdorff JM, Buchman AS. Quantitative mobility metrics from a wearable sensor predict incident parkinsonism in older adults. Parkinsonism Relat Disord. 2019 08; 65:190-196. PMID: 31272924.
      Citations: 14     Fields:    Translation:Humans
    40. Blauwendraat C, Heilbron K, Vallerga CL, Bandres-Ciga S, von Coelln R, Pihlstr?m L, Sim?n-S?nchez J, Schulte C, Sharma M, Krohn L, Siitonen A, Iwaki H, Leonard H, Noyce AJ, Tan M, Gibbs JR, Hernandez DG, Scholz SW, Jankovic J, Shulman LM, Lesage S, Corvol JC, Brice A, van Hilten JJ, Marinus J, Eerola-Rautio J, Tienari P, Majamaa K, Toft M, Grosset DG, Gasser T, Heutink P, Shulman JM, Wood N, Hardy J, Morris HR, Hinds DA, Gratten J, Visscher PM, Gan-Or Z, Nalls MA, Singleton AB. Parkinson's disease age at onset genome-wide association study: Defining heritability, genetic loci, and a-synuclein mechanisms. Mov Disord. 2019 06; 34(6):866-875. PMID: 30957308.
      Citations: 180     Fields:    Translation:Humans
    41. Buchman AS, Yu L, Wilson RS, Leurgans SE, Nag S, Shulman JM, Barnes LL, Schneider JA, Bennett DA. Progressive parkinsonism in older adults is related to the burden of mixed brain pathologies. Neurology. 2019 04 16; 92(16):e1821-e1830. PMID: 30894446.
      Citations: 43     Fields:    Translation:Humans
    42. Ysselstein D, Shulman JM, Krainc D. Emerging links between pediatric lysosomal storage diseases and adult parkinsonism. Mov Disord. 2019 05; 34(5):614-624. PMID: 30726573.
      Citations: 21     Fields:    Translation:Humans
    43. Rousseaux MWC, V?zquez-V?lez GE, Al-Ramahi I, Jeong HH, Bajic A, Revelli JP, Ye H, Phan ET, Deger JM, Perez AM, Kim JY, Lavery LA, Xu Q, Li MZ, Kang H, Kim JJ, Shulman JM, Westbrook TF, Elledge SJ, Liu Z, Botas J, Zoghbi HY. A Druggable Genome Screen Identifies Modifiers of a-Synuclein Levels via a Tiered Cross-Species Validation Approach. J Neurosci. 2018 10 24; 38(43):9286-9301. PMID: 30249792.
      Citations: 28     Fields:    Translation:HumansAnimalsCells
    44. Shulman JM. Reply: Lysosomal storage disorder gene variants in multiple system atrophy. Brain. 2018 07 01; 141(7):e54. PMID: 29741598.
      Citations:    Fields:    Translation:Humans
    45. Guo C, Jeong HH, Hsieh YC, Klein HU, Bennett DA, De Jager PL, Liu Z, Shulman JM. Tau Activates Transposable Elements in Alzheimer's Disease. Cell Rep. 2018 06 05; 23(10):2874-2880. PMID: 29874575.
      Citations: 147     Fields:    Translation:HumansAnimalsCells
    46. Jeong HH, Yalamanchili HK, Guo C, Shulman JM, Liu Z. An ultra-fast and scalable quantification pipeline for transposable elements from next generation sequencing data. Pac Symp Biocomput. 2018; 23:168-179. PMID: 29218879.
      Citations: 48     Fields:    Translation:HumansAnimalsCells
    47. Robak LA, Jansen IE, van Rooij J, Uitterlinden AG, Kraaij R, Jankovic J, Heutink P, Shulman JM. Excessive burden of lysosomal storage disorder gene variants in Parkinson's disease. Brain. 2017 12 01; 140(12):3191-3203. PMID: 29140481.
      Citations: 205     Fields:    Translation:Humans
    48. Rousseaux MWC, Shulman JM, Jankovic J. Progress toward an integrated understanding of Parkinson's disease. F1000Res. 2017; 6:1121. PMID: 28751973.
      Citations: 12     Fields:    
    49. Blauwendraat C, Faghri F, Pihlstrom L, Geiger JT, Elbaz A, Lesage S, Corvol JC, May P, Nicolas A, Abramzon Y, Murphy NA, Gibbs JR, Ryten M, Ferrari R, Bras J, Guerreiro R, Williams J, Sims R, Lubbe S, Hernandez DG, Mok KY, Robak L, Campbell RH, Rogaeva E, Traynor BJ, Chia R, Chung SJ, Hardy JA, Brice A, Wood NW, Houlden H, Shulman JM, Morris HR, Gasser T, Kr?ger R, Heutink P, Sharma M, Sim?n-S?nchez J, Nalls MA, Singleton AB, Scholz SW. NeuroChip, an updated version of the NeuroX genotyping platform to rapidly screen for variants associated with neurological diseases. Neurobiol Aging. 2017 09; 57:247.e9-247.e13. PMID: 28602509.
      Citations: 77     Fields:    Translation:Humans
    50. Wangler MF, Hu Y, Shulman JM. Drosophila and genome-wide association studies: a review and resource for the functional dissection of human complex traits. Dis Model Mech. 2017 02 01; 10(2):77-88. PMID: 28151408.
      Citations: 21     Fields:    Translation:HumansAnimalsCells
    51. Jansen IE, Ye H, Heetveld S, Lechler MC, Michels H, Seinstra RI, Lubbe SJ, Drouet V, Lesage S, Majounie E, Gibbs JR, Nalls MA, Ryten M, Botia JA, Vandrovcova J, Simon-Sanchez J, Castillo-Lizardo M, Rizzu P, Blauwendraat C, Chouhan AK, Li Y, Yogi P, Amin N, van Duijn CM, Morris HR, Brice A, Singleton AB, David DC, Nollen EA, Jain S, Shulman JM, Heutink P. Discovery and functional prioritization of Parkinson's disease candidate genes from large-scale whole exome sequencing. Genome Biol. 2017 01 30; 18(1):22. PMID: 28137300.
      Citations: 61     Fields:    Translation:HumansAnimalsCells
    52. Hales CM, Dammer EB, Deng Q, Duong DM, Gearing M, Troncoso JC, Thambisetty M, Lah JJ, Shulman JM, Levey AI, Seyfried NT. Changes in the detergent-insoluble brain proteome linked to amyloid and tau in Alzheimer's Disease progression. Proteomics. 2016 12; 16(23):3042-3053. PMID: 27718298.
      Citations: 45     Fields:    Translation:Humans
    53. Jakobsdottir J, van der Lee SJ, Bis JC, Chouraki V, Li-Kroeger D, Yamamoto S, Grove ML, Naj A, Vronskaya M, Salazar JL, DeStefano AL, Brody JA, Smith AV, Amin N, Sims R, Ibrahim-Verbaas CA, Choi SH, Satizabal CL, Lopez OL, Beiser A, Ikram MA, Garcia ME, Hayward C, Varga TV, Ripatti S, Franks PW, Hallmans G, Rolandsson O, Jansson JH, Porteous DJ, Salomaa V, Eiriksdottir G, Rice KM, Bellen HJ, Levy D, Uitterlinden AG, Emilsson V, Rotter JI, Aspelund T, O'Donnell CJ, Fitzpatrick AL, Launer LJ, Hofman A, Wang LS, Williams J, Schellenberg GD, Boerwinkle E, Psaty BM, Seshadri S, Shulman JM, Gudnason V, van Duijn CM. Rare Functional Variant in TM2D3 is Associated with Late-Onset Alzheimer's Disease. PLoS Genet. 2016 Oct; 12(10):e1006327. PMID: 27764101.
      Citations: 27     Fields:    Translation:HumansAnimals
    54. M?ller SH, Girard SL, Hopfner F, Merner ND, Bourassa CV, Lorenz D, Clark LN, Tittmann L, Soto-Ortolaza AI, Klebe S, Hallett M, Schneider SA, Hodgkinson CA, Lieb W, Wszolek ZK, Pendziwiat M, Lorenzo-Betancor O, Poewe W, Ortega-Cubero S, Seppi K, Rajput A, Hussl A, Rajput AH, Berg D, Dion PA, Wurster I, Shulman JM, Srulijes K, Haubenberger D, Pastor P, Vilari?o-G?ell C, Postuma RB, Bernard G, Ladwig KH, Dupr? N, Jankovic J, Strauch K, Panisset M, Winkelmann J, Testa CM, Reischl E, Zeuner KE, Ross OA, Arzberger T, Chouinard S, Deuschl G, Louis ED, Kuhlenb?umer G, Rouleau GA. Genome-wide association study in essential tremor identifies three new loci. Brain. 2016 12; 139(Pt 12):3163-3169. PMID: 27797806.
      Citations: 40     Fields:    Translation:Humans
    55. Giri A, Mok KY, Jansen I, Sharma M, Tesson C, Mangone G, Lesage S, Bras JM, Shulman JM, Sheerin UM, D?ez-Fairen M, Pastor P, Mart? MJ, Ezquerra M, Tolosa E, Correia-Guedes L, Ferreira J, Amin N, van Duijn CM, van Rooij J, Uitterlinden AG, Kraaij R, Nalls M, Sim?n-S?nchez J. Lack of evidence for a role of genetic variation in TMEM230 in the risk for Parkinson's disease in the Caucasian population. Neurobiol Aging. 2017 02; 50:167.e11-167.e13. PMID: 27818000.
      Citations: 12     Fields:    Translation:Humans
    56. Buchman AS, Leurgans SE, Yu L, Wilson RS, Lim AS, James BD, Shulman JM, Bennett DA. Incident parkinsonism in older adults without Parkinson disease. Neurology. 2016 Sep 06; 87(10):1036-44. PMID: 27488597.
      Citations: 43     Fields:    Translation:Humans
    57. Valenca GT, Srivastava GP, Oliveira-Filho J, White CC, Yu L, Schneider JA, Buchman AS, Shulman JM, Bennett DA, De Jager PL. The Role of MAPT Haplotype H2 and Isoform 1N/4R in Parkinsonism of Older Adults. PLoS One. 2016; 11(7):e0157452. PMID: 27458716.
      Citations: 13     Fields:    Translation:HumansCells
    58. Chouhan AK, Guo C, Hsieh YC, Ye H, Senturk M, Zuo Z, Li Y, Chatterjee S, Botas J, Jackson GR, Bellen HJ, Shulman JM. Uncoupling neuronal death and dysfunction in Drosophila models of neurodegenerative disease. Acta Neuropathol Commun. 2016 06 23; 4(1):62. PMID: 27338814.
      Citations: 39     Fields:    Translation:HumansAnimalsCells
    59. Ali YO, Allen HM, Yu L, Li-Kroeger D, Bakhshizadehmahmoudi D, Hatcher A, McCabe C, Xu J, Bjorklund N, Taglialatela G, Bennett DA, De Jager PL, Shulman JM, Bellen HJ, Lu HC. NMNAT2:HSP90 Complex Mediates Proteostasis in Proteinopathies. PLoS Biol. 2016 06; 14(6):e1002472. PMID: 27254664.
      Citations: 72     Fields:    Translation:HumansAnimalsCells
    60. Farlow JL, Robak LA, Hetrick K, Bowling K, Boerwinkle E, Coban-Akdemir ZH, Gambin T, Gibbs RA, Gu S, Jain P, Jankovic J, Jhangiani S, Kaw K, Lai D, Lin H, Ling H, Liu Y, Lupski JR, Muzny D, Porter P, Pugh E, White J, Doheny K, Myers RM, Shulman JM, Foroud T. Whole-Exome Sequencing in Familial Parkinson Disease. JAMA Neurol. 2016 Jan; 73(1):68-75. PMID: 26595808.
      Citations: 40     Fields:    Translation:Humans
    61. Buchman AS, Wilson RS, Shulman JM, Leurgans SE, Schneider JA, Bennett DA. Parkinsonism in Older Adults and Its Association With Adverse Health Outcomes and Neuropathology. J Gerontol A Biol Sci Med Sci. 2016 Apr; 71(4):549-56. PMID: 26362440.
      Citations: 37     Fields:    Translation:Humans
    62. Wijemanne S, Shulman JM, Jimenez-Shahed J, Curry D, Jankovic J. SPG11 Mutations Associated With a Complex Phenotype Resembling Dopa-Responsive Dystonia. Mov Disord Clin Pract. 2015 Jun; 2(2):149-154. PMID: 30363882.
      Citations: 7     Fields:    
    63. Shulman JM. Drosophila and experimental neurology in the post-genomic era. Exp Neurol. 2015 Dec; 274(Pt A):4-13. PMID: 25814441.
      Citations: 7     Fields:    Translation:HumansAnimals
    64. Debette S, Ibrahim Verbaas CA, Bressler J, Schuur M, Smith A, Bis JC, Davies G, Wolf C, Gudnason V, Chibnik LB, Yang Q, deStefano AL, de Quervain DJ, Srikanth V, Lahti J, Grabe HJ, Smith JA, Priebe L, Yu L, Karbalai N, Hayward C, Wilson JF, Campbell H, Petrovic K, Fornage M, Chauhan G, Yeo R, Boxall R, Becker J, Stegle O, Mather KA, Chouraki V, Sun Q, Rose LM, Resnick S, Oldmeadow C, Kirin M, Wright AF, Jonsdottir MK, Au R, Becker A, Amin N, Nalls MA, Turner ST, Kardia SL, Oostra B, Windham G, Coker LH, Zhao W, Knopman DS, Heiss G, Griswold ME, Gottesman RF, Vitart V, Hastie ND, Zgaga L, Rudan I, Polasek O, Holliday EG, Schofield P, Choi SH, Tanaka T, An Y, Perry RT, Kennedy RE, Sale MM, Wang J, Wadley VG, Liewald DC, Ridker PM, Gow AJ, Pattie A, Starr JM, Porteous D, Liu X, Thomson R, Armstrong NJ, Eiriksdottir G, Assareh AA, Kochan NA, Widen E, Palotie A, Hsieh YC, Eriksson JG, Vogler C, van Swieten JC, Shulman JM, Beiser A, Rotter J, Schmidt CO, Hoffmann W, N?then MM, Ferrucci L, Attia J, Uitterlinden AG, Amouyel P, Dartigues JF, Amieva H, R?ikk?nen K, Garcia M, Wolf PA, Hofman A, Longstreth WT, Psaty BM, Boerwinkle E, DeJager PL, Sachdev PS, Schmidt R, Breteler MM, Teumer A, Lopez OL, Cichon S, Chasman DI, Grodstein F, M?ller-Myhsok B, Tzourio C, Papassotiropoulos A, Bennett DA, Ikram MA, Deary IJ, van Duijn CM, Launer L, Fitzpatrick AL, Seshadri S, Mosley TH. Genome-wide studies of verbal declarative memory in nondemented older people: the Cohorts for Heart and Aging Research in Genomic Epidemiology consortium. Biol Psychiatry. 2015 Apr 15; 77(8):749-63. PMID: 25648963.
      Citations: 42     Fields:    Translation:Humans
    65. Haelterman NA, Yoon WH, Sandoval H, Jaiswal M, Shulman JM, Bellen HJ. A mitocentric view of Parkinson's disease. Annu Rev Neurosci. 2014; 37:137-59. PMID: 24821430.
      Citations: 64     Fields:    Translation:HumansAnimalsCells
    66. Buchman AS, Yu L, Wilson RS, Shulman JM, Boyle PA, Bennett DA. Harm avoidance is associated with progression of parkinsonism in community-dwelling older adults: a prospective cohort study. BMC Geriatr. 2014 Apr 23; 14:54. PMID: 24754876.
      Citations: 4     Fields:    Translation:Humans
    67. Shulman JM, Yu L, Buchman AS, Evans DA, Schneider JA, Bennett DA, De Jager PL. Association of Parkinson disease risk loci with mild parkinsonian signs in older persons. JAMA Neurol. 2014 Apr; 71(4):429-35. PMID: 24514572.
      Citations: 27     Fields:    Translation:HumansCells
    68. Shulman JM. Structural variation and the expanding genomic architecture of Parkinson disease. JAMA Neurol. 2013 Nov; 70(11):1355-6. PMID: 24018918.
      Citations: 2     Fields:    Translation:Humans
    69. Shulman JM, Imboywa S, Giagtzoglou N, Powers MP, Hu Y, Devenport D, Chipendo P, Chibnik LB, Diamond A, Perrimon N, Brown NH, De Jager PL, Feany MB. Functional screening in Drosophila identifies Alzheimer's disease susceptibility genes and implicates Tau-mediated mechanisms. Hum Mol Genet. 2014 Feb 15; 23(4):870-7. PMID: 24067533.
      Citations: 88     Fields:    Translation:HumansAnimals
    70. Shulman JM, Chen K, Keenan BT, Chibnik LB, Fleisher A, Thiyyagura P, Roontiva A, McCabe C, Patsopoulos NA, Corneveaux JJ, Yu L, Huentelman MJ, Evans DA, Schneider JA, Reiman EM, De Jager PL, Bennett DA. Genetic susceptibility for Alzheimer disease neuritic plaque pathology. JAMA Neurol. 2013 Sep 01; 70(9):1150-7. PMID: 23836404.
      Citations: 95     Fields:    Translation:Humans
    71. Cruchaga C, Kauwe JS, Harari O, Jin SC, Cai Y, Karch CM, Benitez BA, Jeng AT, Skorupa T, Carrell D, Bertelsen S, Bailey M, McKean D, Shulman JM, De Jager PL, Chibnik L, Bennett DA, Arnold SE, Harold D, Sims R, Gerrish A, Williams J, Van Deerlin VM, Lee VM, Shaw LM, Trojanowski JQ, Haines JL, Mayeux R, Pericak-Vance MA, Farrer LA, Schellenberg GD, Peskind ER, Galasko D, Fagan AM, Holtzman DM, Morris JC, Goate AM. GWAS of cerebrospinal fluid tau levels identifies risk variants for Alzheimer's disease. Neuron. 2013 Apr 24; 78(2):256-68. PMID: 23562540.
      Citations: 227     Fields:    Translation:HumansCells
    72. Sherva R, Tripodis Y, Bennett DA, Chibnik LB, Crane PK, de Jager PL, Farrer LA, Saykin AJ, Shulman JM, Naj A, Green RC. Genome-wide association study of the rate of cognitive decline in Alzheimer's disease. Alzheimers Dement. 2014 Jan; 10(1):45-52. PMID: 23535033.
      Citations: 92     Fields:    Translation:Humans
    73. Bhama JK, Shulman J, Bermudez CA, Bansal A, Ramani R, Teuteberg JJ, Shullo M, McNamara DM, Kormos RL, Toyoda Y. Heart transplantation for adults with congenital heart disease: results in the modern era. J Heart Lung Transplant. 2013 May; 32(5):499-504. PMID: 23474360.
      Citations: 10     Fields:    Translation:Humans
    74. Hek K, Demirkan A, Lahti J, Terracciano A, Teumer A, Cornelis MC, Amin N, Bakshis E, Baumert J, Ding J, Liu Y, Marciante K, Meirelles O, Nalls MA, Sun YV, Vogelzangs N, Yu L, Bandinelli S, Benjamin EJ, Bennett DA, Boomsma D, Cannas A, Coker LH, de Geus E, De Jager PL, Diez-Roux AV, Purcell S, Hu FB, Rimma EB, Hunter DJ, Jensen MK, Curhan G, Rice K, Penman AD, Rotter JI, Sotoodehnia N, Emeny R, Eriksson JG, Evans DA, Ferrucci L, Fornage M, Gudnason V, Hofman A, Illig T, Kardia S, Kelly-Hayes M, Koenen K, Kraft P, Kuningas M, Massaro JM, Melzer D, Mulas A, Mulder CL, Murray A, Oostra BA, Palotie A, Penninx B, Petersmann A, Pilling LC, Psaty B, Rawal R, Reiman EM, Schulz A, Shulman JM, Singleton AB, Smith AV, Sutin AR, Uitterlinden AG, V?lzke H, Widen E, Yaffe K, Zonderman AB, Cucca F, Harris T, Ladwig KH, Llewellyn DJ, R?ikk?nen K, Tanaka T, van Duijn CM, Grabe HJ, Launer LJ, Lunetta KL, Mosley TH, Newman AB, Tiemeier H, Murabito J. A genome-wide association study of depressive symptoms. Biol Psychiatry. 2013 Apr 01; 73(7):667-78. PMID: 23290196.
      Citations: 86     Fields:    Translation:HumansCells
    75. Buchman AS, Nag S, Shulman JM, Lim AS, VanderHorst VG, Leurgans SE, Schneider JA, Bennett DA. Locus coeruleus neuron density and parkinsonism in older adults without Parkinson's disease. Mov Disord. 2012 Nov; 27(13):1625-31. PMID: 23038629.
      Citations: 31     Fields:    Translation:HumansCells
    76. Shulman JM, Schneider JA. Molecular mechanisms of cortical degeneration in Parkinson disease. Neurology. 2012 Oct 23; 79(17):1750-1. PMID: 23019261.
      Citations:    Fields:    Translation:Humans
    77. Lim AS, Chang AM, Shulman JM, Raj T, Chibnik LB, Cain SW, Rothamel K, Benoist C, Myers AJ, Czeisler CA, Buchman AS, Bennett DA, Duffy JF, Saper CB, De Jager PL. A common polymorphism near PER1 and the timing of human behavioral rhythms. Ann Neurol. 2012 Sep; 72(3):324-34. PMID: 23034908.
      Citations: 19     Fields:    Translation:HumansCells
    78. Bis JC, DeCarli C, Smith AV, van der Lijn F, Crivello F, Fornage M, Debette S, Shulman JM, Schmidt H, Srikanth V, Schuur M, Yu L, Choi SH, Sigurdsson S, Verhaaren BF, DeStefano AL, Lambert JC, Jack CR, Struchalin M, Stankovich J, Ibrahim-Verbaas CA, Fleischman D, Zijdenbos A, den Heijer T, Mazoyer B, Coker LH, Enzinger C, Danoy P, Amin N, Arfanakis K, van Buchem MA, de Bruijn RF, Beiser A, Dufouil C, Huang J, Cavalieri M, Thomson R, Niessen WJ, Chibnik LB, Gislason GK, Hofman A, Pikula A, Amouyel P, Freeman KB, Phan TG, Oostra BA, Stein JL, Medland SE, Vasquez AA, Hibar DP, Wright MJ, Franke B, Martin NG, Thompson PM, Nalls MA, Uitterlinden AG, Au R, Elbaz A, Beare RJ, van Swieten JC, Lopez OL, Harris TB, Chouraki V, Breteler MM, De Jager PL, Becker JT, Vernooij MW, Knopman D, Fazekas F, Wolf PA, van der Lugt A, Gudnason V, Longstreth WT, Brown MA, Bennett DA, van Duijn CM, Mosley TH, Schmidt R, Tzourio C, Launer LJ, Ikram MA, Seshadri S. Common variants at 12q14 and 12q24 are associated with hippocampal volume. Nat Genet. 2012 Apr 15; 44(5):545-51. PMID: 22504421.
      Citations: 135     Fields:    Translation:HumansCells
    79. Valant V, Keenan BT, Anderson CD, Shulman JM, Devan WJ, Ayres AM, Schwab K, Goldstein JN, Viswanathan A, Greenberg SM, Bennett DA, De Jager PL, Rosand J, Biffi A. TOMM40 in Cerebral Amyloid Angiopathy Related Intracerebral Hemorrhage: Comparative Genetic Analysis with Alzheimer's Disease. Transl Stroke Res. 2012 Jul; 3(Suppl 1):102-12. PMID: 24323865.
      Citations: 10     Fields:    
    80. Raj T, Shulman JM, Keenan BT, Chibnik LB, Evans DA, Bennett DA, Stranger BE, De Jager PL. Alzheimer disease susceptibility loci: evidence for a protein network under natural selection. Am J Hum Genet. 2012 Apr 06; 90(4):720-6. PMID: 22482808.
      Citations: 42     Fields:    Translation:Humans
    81. Keenan BT, Shulman JM, Chibnik LB, Raj T, Tran D, Sabuncu MR, Allen AN, Corneveaux JJ, Hardy JA, Huentelman MJ, Lemere CA, Myers AJ, Nicholson-Weller A, Reiman EM, Evans DA, Bennett DA, De Jager PL. A coding variant in CR1 interacts with APOE-e4 to influence cognitive decline. Hum Mol Genet. 2012 May 15; 21(10):2377-88. PMID: 22343410.
      Citations: 58     Fields:    Translation:Humans
    82. Buchman AS, Shulman JM, Nag S, Leurgans SE, Arnold SE, Morris MC, Schneider JA, Bennett DA. Nigral pathology and parkinsonian signs in elders without Parkinson disease. Ann Neurol. 2012 Feb; 71(2):258-66. PMID: 22367997.
      Citations: 124     Fields:    Translation:HumansCells
    83. Yu L, Shulman JM, Chibnik L, Leurgans S, Schneider JA, De Jager PL, Bennett DA. The CETP I405V polymorphism is associated with an increased risk of Alzheimer's disease. Aging Cell. 2012 Apr; 11(2):228-33. PMID: 22122979.
      Citations: 12     Fields:    Translation:Humans
    84. De Jager PL, Shulman JM, Chibnik LB, Keenan BT, Raj T, Wilson RS, Yu L, Leurgans SE, Tran D, Aubin C, Anderson CD, Biffi A, Corneveaux JJ, Huentelman MJ, Rosand J, Daly MJ, Myers AJ, Reiman EM, Bennett DA, Evans DA. A genome-wide scan for common variants affecting the rate of age-related cognitive decline. Neurobiol Aging. 2012 May; 33(5):1017.e1-15. PMID: 22054870.
      Citations: 108     Fields:    Translation:Humans
    85. Treusch S, Hamamichi S, Goodman JL, Matlack KE, Chung CY, Baru V, Shulman JM, Parrado A, Bevis BJ, Valastyan JS, Han H, Lindhagen-Persson M, Reiman EM, Evans DA, Bennett DA, Olofsson A, DeJager PL, Tanzi RE, Caldwell KA, Caldwell GA, Lindquist S. Functional links between A? toxicity, endocytic trafficking, and Alzheimer's disease risk factors in yeast. Science. 2011 Dec 02; 334(6060):1241-5. PMID: 22033521.
      Citations: 186     Fields:    Translation:HumansAnimalsCells
    86. Chibnik LB, Shulman JM, Leurgans SE, Schneider JA, Wilson RS, Tran D, Aubin C, Buchman AS, Heward CB, Myers AJ, Hardy JA, Huentelman MJ, Corneveaux JJ, Reiman EM, Evans DA, Bennett DA, De Jager PL. CR1 is associated with amyloid plaque burden and age-related cognitive decline. Ann Neurol. 2011 Mar; 69(3):560-9. PMID: 21391232.
      Citations: 97     Fields:    Translation:Humans
    87. Shulman JM, Chipendo P, Chibnik LB, Aubin C, Tran D, Keenan BT, Kramer PL, Schneider JA, Bennett DA, Feany MB, De Jager PL. Functional screening of Alzheimer pathology genome-wide association signals in Drosophila. Am J Hum Genet. 2011 Feb 11; 88(2):232-8. PMID: 21295279.
      Citations: 43     Fields:    Translation:HumansAnimalsCells
    88. Shulman JM, De Jager PL, Feany MB. Parkinson's disease: genetics and pathogenesis. Annu Rev Pathol. 2011; 6:193-222. PMID: 21034221.
      Citations: 355     Fields:    Translation:HumansAnimalsCells
    89. Xia Z, Chibnik LB, Glanz BI, Liguori M, Shulman JM, Tran D, Khoury SJ, Chitnis T, Holyoak T, Weiner HL, Guttmann CR, De Jager PL. A putative Alzheimer's disease risk allele in PCK1 influences brain atrophy in multiple sclerosis. PLoS One. 2010 Nov 30; 5(11):e14169. PMID: 21152065.
      Citations: 12     Fields:    Translation:Humans
    90. Shulman JM, Chibnik LB, Aubin C, Schneider JA, Bennett DA, De Jager PL. Intermediate phenotypes identify divergent pathways to Alzheimer's disease. PLoS One. 2010 Jun 21; 5(6):e11244. PMID: 20574532.
      Citations: 28     Fields:    Translation:HumansCells
    91. Corneveaux JJ, Myers AJ, Allen AN, Pruzin JJ, Ramirez M, Engel A, Nalls MA, Chen K, Lee W, Chewning K, Villa SE, Meechoovet HB, Gerber JD, Frost D, Benson HL, O'Reilly S, Chibnik LB, Shulman JM, Singleton AB, Craig DW, Van Keuren-Jensen KR, Dunckley T, Bennett DA, De Jager PL, Heward C, Hardy J, Reiman EM, Huentelman MJ. Association of CR1, CLU and PICALM with Alzheimer's disease in a cohort of clinically characterized and neuropathologically verified individuals. Hum Mol Genet. 2010 Aug 15; 19(16):3295-301. PMID: 20534741.
      Citations: 135     Fields:    Translation:Humans
    92. Shulman JM, De Jager PL. Evidence for a common pathway linking neurodegenerative diseases. Nat Genet. 2009 Dec; 41(12):1261-2. PMID: 19935760.
      Citations: 16     Fields:    Translation:Humans
    93. Alcalay RN, Shulman JM, Plotkin SR. Ramsay Hunt syndrome in a patient with metastatic lung cancer to brain. J Neurooncol. 2008 Jan; 86(1):55-6. PMID: 17634859.
      Citations:    Fields:    Translation:Humans
    94. Steinhilb ML, Dias-Santagata D, Mulkearns EE, Shulman JM, Biernat J, Mandelkow EM, Feany MB. S/P and T/P phosphorylation is critical for tau neurotoxicity in Drosophila. J Neurosci Res. 2007 May 01; 85(6):1271-8. PMID: 17335084.
      Citations: 57     Fields:    Translation:AnimalsCells
    95. Khurana V, Lu Y, Steinhilb ML, Oldham S, Shulman JM, Feany MB. TOR-mediated cell-cycle activation causes neurodegeneration in a Drosophila tauopathy model. Curr Biol. 2006 Feb 07; 16(3):230-41. PMID: 16461276.
      Citations: 144     Fields:    Translation:AnimalsCells
    96. Shulman JM. Surgical lessons from Shakespeare. Curr Surg. 2004 Jan-Feb; 61(1):96-7. PMID: 14972180.
      Citations:    Fields:    Translation:Humans
    97. Shulman JM, Feany MB. Genetic modifiers of tauopathy in Drosophila. Genetics. 2003 Nov; 165(3):1233-42. PMID: 14668378.
      Citations: 110     Fields:    Translation:Animals
    98. Doerflinger H, Benton R, Shulman JM, St Johnston D. The role of PAR-1 in regulating the polarised microtubule cytoskeleton in the Drosophila follicular epithelium. Development. 2003 Sep; 130(17):3965-75. PMID: 12874119.
      Citations: 74     Fields:    Translation:AnimalsCells
    99. Shulman JM, Shulman LM, Weiner WJ, Feany MB. From fruit fly to bedside: translating lessons from Drosophila models of neurodegenerative disease. Curr Opin Neurol. 2003 Aug; 16(4):443-9. PMID: 12869801.
      Citations: 38     Fields:    Translation:HumansAnimals
    100. Tree DR, Shulman JM, Rousset R, Scott MP, Gubb D, Axelrod JD. Prickle mediates feedback amplification to generate asymmetric planar cell polarity signaling. Cell. 2002 May 03; 109(3):371-81. PMID: 12015986.
      Citations: 183     Fields:    Translation:HumansAnimalsCells
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