Alzheimer Disease

"Alzheimer Disease" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure, which enables searching at various levels of specificity.

MeSH information

Definition | Details | More General Concepts | Related Concepts | More Specific Concepts

A degenerative disease of the BRAIN characterized by the insidious onset of DEMENTIA. Impairment of MEMORY, judgment, attention span, and problem solving skills are followed by severe APRAXIAS and a global loss of cognitive abilities. The condition primarily occurs after age 60, and is marked pathologically by severe cortical atrophy and the triad of SENILE PLAQUES; NEUROFIBRILLARY TANGLES; and NEUROPIL THREADS. (From Adams et al., Principles of Neurology, 6th ed, pp1049-57)

Descriptor ID	D000544
MeSH Number(s)	C10.228.140.380.100 C10.574.945.249 F03.615.400.100
Concept/Terms	Alzheimer Disease Alzheimer Disease Alzheimer's Disease Dementia, Senile Senile Dementia Dementia, Alzheimer Type Alzheimer Type Dementia Alzheimer-Type Dementia (ATD) Alzheimer Type Dementia (ATD) Dementia, Alzheimer-Type (ATD) Alzheimer Type Senile Dementia Primary Senile Degenerative Dementia Dementia, Primary Senile Degenerative Alzheimer Sclerosis Sclerosis, Alzheimer Alzheimer Syndrome Alzheimer Dementia Alzheimer Dementias Dementia, Alzheimer Dementias, Alzheimer Senile Dementia, Alzheimer Type Acute Confusional Senile Dementia Acute Confusional Senile Dementia Senile Dementia, Acute Confusional Dementia, Presenile Dementia, Presenile Presenile Dementia Alzheimer Disease, Late Onset Alzheimer Disease, Late Onset Late Onset Alzheimer Disease Alzheimer's Disease, Focal Onset Alzheimer's Disease, Focal Onset Focal Onset Alzheimer's Disease Familial Alzheimer Disease (FAD) Familial Alzheimer Disease (FAD) Alzheimer Disease, Familial (FAD) Alzheimer Diseases, Familial (FAD) Familial Alzheimer Diseases (FAD) Alzheimer Disease, Early Onset Alzheimer Disease, Early Onset Early Onset Alzheimer Disease Presenile Alzheimer Dementia

Below are MeSH descriptors whose meaning is more general than "Alzheimer Disease".

Diseases [C]
Nervous System Diseases [C10]
Central Nervous System Diseases [C10.228]
Brain Diseases [C10.228.140]
Dementia [C10.228.140.380]
Alzheimer Disease [C10.228.140.380.100]
Neurodegenerative Diseases [C10.574]
Tauopathies [C10.574.945]
Alzheimer Disease [C10.574.945.249]
Psychiatry and Psychology [F]
Mental Disorders [F03]
Neurocognitive Disorders [F03.615]
Dementia [F03.615.400]
Alzheimer Disease [F03.615.400.100]

Below are MeSH descriptors whose meaning is related to "Alzheimer Disease".

Below are MeSH descriptors whose meaning is more specific than "Alzheimer Disease".

publications

Timeline | Most Recent

This graph shows the total number of publications written about "Alzheimer Disease" by people in this website by year, and whether "Alzheimer Disease" was a major or minor topic of these publications.

Bar chart showing 811 publications over 30 distinct years, with a maximum of 38 publications in 2011 and 2023

To see the data from this visualization as text, click here.

Year	Major Topic	Minor Topic	Total
1996	13	1	14
1997	8	2	10
1998	17	1	18
1999	11	3	14
2000	17	4	21
2001	11	4	15
2002	29	8	37
2003	20	4	24
2004	32	2	34
2005	30	6	36
2006	32	3	35
2007	33	3	36
2008	27	5	32
2009	27	8	35
2010	29	4	33
2011	27	11	38
2012	13	5	18
2013	32	1	33
2014	14	1	15
2015	21	0	21
2016	22	6	28
2017	23	3	26
2018	29	3	32
2019	15	3	18
2020	30	3	33
2021	21	4	25
2022	27	0	27
2023	38	0	38
2024	34	3	37
2025	27	1	28

Below are the most recent publications written about "Alzheimer Disease" by people in Profiles.

Park SY, Setiawan VW, Crimmins EM, White LR, Haiman CA, Wilkens LR, Le Marchand L, Lim U. Plant-Based Dietary Patterns and Risk of Alzheimer Disease and Related Dementias in the Multiethnic Cohort Study. Neurology. 2026 May 12; 106(9):e214916.

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Saarah P, Syeda ZA, Xu Z, Dong Y, Jiang H, Shanguhyia M, Roy S, Zhu B, Zhang L, Dewan AT, Asgari S, Alagpulinsa DA. Shared genetic and neuroimmune architecture links type 1 diabetes with neurocognitive traits. Nat Commun. 2026 Mar 13; 17(1).

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Mamani S, Sordillo LA, Alfano RR. Femtosecond Optical Kerr Effect in Alzheimer's Brain Tissue. J Biophotonics. 2026 Mar; 19(3):e70244.

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Zhou J, Yang Y, Liu S, Chen J, Liao H, Liang W, Zhang Z, Wang Y, Liu Y, Zhang H, Jiang H, Lin W, Qu J, Barger SW, Wu S. Microglial serine racemase knockout alleviates Alzheimer-like neuropathology and behavioral deficit via lactylation-mediated anti-inflammation. Commun Biol. 2026 Feb 25; 9(1).

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da Silva AMP, Janu?rio Campos Cardoso L, Batista S, Gon?alves OR, Paranhos T, Teixeira IPS, Guimar?es PD, Espinosa Franco B, Cal H, Salles JEN, Perry G, H?ilund-Carlsen PF, Santos DH. Tirzepatide versus semaglutide for the prevention of mild cognitive impairment, dementia, and Alzheimer's disease in type 2 diabetes: A real-world, retrospective cohort study. J Diabetes Complications. 2026 May; 40(5):109306.

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da Silva AMP, de Deus O, Janu?rio Campos Cardoso L, Virgilio Ribeiro F, Froelich Meldola P, Rodrigues Menezes I, Lee Han M, Quiroga DG, James Almeida K, Haddad Santos D, Perry G, H?ilund-Carlsen PF, de Souza Franco E, de Sousa Maia MB. Efficacy, safety, and ARIA risk of anti-?-amyloid antibodies in early Alzheimer's disease: a systematic review, meta-analysis, and meta-regression. Expert Opin Biol Ther. 2026 Jan-Feb; 26(2):177-188.

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Zhao P, El Fadel O, Le A, Mangleburg CG, Dhindsa J, Wu T, Zhao J, Huang M, Amoh B, Marella AS, Li Y, Seyfried NT, Levey AI, Liu Z, Al-Ramahi I, Botas J, Shulman JM. Systems genetic dissection of brain gene expression reveals excitotoxic mechanisms of Alzheimer's disease. Mol Psychiatry. 2026 Jun; 31(6):3462-3481.

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Morovati A, Moussa Y, Kalupahana NS, Zu Y, Jun H, Fokar M, Moustaid-Moussa N. Neuroinflammation in Alzheimer's Disease: The Role of Obesity, Gut Microbiota, and Therapeutic Potential of Omega-3 Fatty Acids and Neural Stem Cells. J Nutr. 2026 04; 156(4):101407.

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Elia A, Parodi-Rullan R, Vazquez-Torres R, Carey A, Zhao H, Javadov S, Fossati S. Amyloid ? Instigates Cardiac Neurotrophic Signaling Impairment, Driving Alzheimer's Associated Heart Disease. Adv Sci (Weinh). 2026 Apr; 13(20):e11924.

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Dorfsman DA, Cai D, Hamilton-Nelson KL, Adams LD, Mena PR, Rodriguez VC, Sanchez JJ, Valladares GS, Lopez M, Whitehead PL, Prough MB, Manrique P, Martinez A, Mas SM, Scaramutti C, Acosta H, Silva-Vergara C, McInerney K, Griswold AJ, Feliciano-Astacio BE, Cuccaro ML, Kunkle BW, Reitz C, Tosto G, Bush WS, Haines JL, Akinyemi JO, Akinyemi RO, Ogunniyi A, Byrd GS, Vance JM, Celis K, Seixas A, Pericak-Vance MA, Rajabli F. Educational attainment is associated with reduced functional decline in Puerto Ricans with elevated pTau181. J Alzheimers Dis. 2026 Mar; 110(2):685-695.

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