A degenerative disease of the central nervous system characterized by balance difficulties; OCULAR MOTILITY DISORDERS (supranuclear ophthalmoplegia); DYSARTHRIA; swallowing difficulties; and axial DYSTONIA. Onset is usually in the fifth decade and disease progression occurs over several years. Pathologic findings include neurofibrillary degeneration and neuronal loss in the dorsal MESENCEPHALON; SUBTHALAMIC NUCLEUS; RED NUCLEUS; pallidum; dentate nucleus; and vestibular nuclei. (From Adams et al., Principles of Neurology, 6th ed, pp1076-7)

Descriptor ID	D013494
MeSH Number(s)	C10.228.140.079.882 C10.228.662.700 C10.292.562.750.500 C10.574.945.500 C10.597.622.447.690 C11.590.472.500 C23.888.592.636.447.690
Concept/Terms	Supranuclear Palsy, Progressive Supranuclear Palsy, Progressive Progressive Supranuclear Palsies Supranuclear Palsies, Progressive Palsy, Progressive Supranuclear Progressive Supranuclear Ophthalmoplegia Progressive Supranuclear Palsy Steele-Richardson-Olszewski Disease Steele Richardson Olszewski Disease Steele-Richardson-Olszewski Syndrome Steele Richardson Olszewski Syndrome Syndrome, Steele-Richardson-Olszewski Supranuclear Palsy, Progressive, 1 Ophthalmoplegia, Progressive Supranuclear Supranuclear Ophthalmoplegia, Progressive Richardson's Syndrome Richardson Syndrome Syndrome, Richardson's

Below are MeSH descriptors whose meaning is more general than "Supranuclear Palsy, Progressive".

Below are MeSH descriptors whose meaning is related to "Supranuclear Palsy, Progressive".

Below are MeSH descriptors whose meaning is more specific than "Supranuclear Palsy, Progressive".