"A Kinase Anchor Proteins" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A structurally-diverse family of intracellular-signaling adaptor proteins that selectively tether specific protein kinase A subtypes to distinct subcellular sites. They play a role in focusing the PROTEIN KINASE A activity toward relevant substrates. Over fifty members of this family exist, most of which bind specifically to regulatory subunits of CYCLIC AMP-DEPENDENT PROTEIN KINASE TYPE II such as CAMP PROTEIN KINASE RIIALPHA or CAMP PROTEIN KINASE RIIBETA.
| Descriptor ID |
D054758
|
| MeSH Number(s) |
D12.644.360.024.065 D12.776.157.057.003 D12.776.476.024.069
|
| Concept/Terms |
A Kinase Anchor Proteins- A Kinase Anchor Proteins
- Protein Kinase A Anchor Proteins
- A-Kinase Anchor Proteins
- Anchor Proteins, A-Kinase
|
Below are MeSH descriptors whose meaning is more general than "A Kinase Anchor Proteins".
Below are MeSH descriptors whose meaning is more specific than "A Kinase Anchor Proteins".
This graph shows the total number of publications written about "A Kinase Anchor Proteins" by people in this website by year, and whether "A Kinase Anchor Proteins" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2002 | 0 | 1 | 1 |
| 2006 | 0 | 1 | 1 |
| 2007 | 0 | 1 | 1 |
| 2015 | 1 | 0 | 1 |
| 2018 | 1 | 0 | 1 |
| 2021 | 1 | 0 | 1 |
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Below are the most recent publications written about "A Kinase Anchor Proteins" by people in Profiles.
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Zhang S, Wang H, Melick CH, Jeong MH, Curukovic A, Tiwary S, Lama-Sherpa TD, Meng D, Servage KA, James NG, Jewell JL. AKAP13 couples GPCR signaling to mTORC1 inhibition. PLoS Genet. 2021 10; 17(10):e1009832.
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Rivera-Pag?n AF, M?ndez-Gonz?lez MP, Rivera-Aponte DE, Malpica-Nieves CJ, Melnik-Mart?nez KV, Zayas-Santiago A, Maldonado-Mart?nez G, Shuba YM, Skatchkov SN, Eaton MJ. A-Kinase-Anchoring Protein (AKAP150) is expressed in Astrocytes and Upregulated in Response to Ischemia. Neuroscience. 2018 08 01; 384:54-63.
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Wise A, Tenezaca L, Fernandez RW, Schatoff E, Flores J, Ueda A, Zhong X, Wu CF, Simon AF, Venkatesh T. Drosophila mutants of the autism candidate gene neurobeachin (rugose) exhibit neuro-developmental disorders, aberrant synaptic properties, altered locomotion, and impaired adult social behavior and activity patterns. J Neurogenet. 2015; 29(2-3):135-43.
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Chai S, Li M, Lan J, Xiong ZG, Saugstad JA, Simon RP. A kinase-anchoring protein 150 and calcineurin are involved in regulation of acid-sensing ion channels ASIC1a and ASIC2a. J Biol Chem. 2007 Aug 03; 282(31):22668-77.
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Wilson GM, Flibotte S, Chopra V, Melnyk BL, Honer WG, Holt RA. DNA copy-number analysis in bipolar disorder and schizophrenia reveals aberrations in genes involved in glutamate signaling. Hum Mol Genet. 2006 Mar 01; 15(5):743-9.
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Shamloula HK, Mbogho MP, Pimentel AC, Chrzanowska-Lightowlers ZM, Hyatt V, Okano H, Venkatesh TR. rugose (rg), a Drosophila A kinase anchor protein, is required for retinal pattern formation and interacts genetically with multiple signaling pathways. Genetics. 2002 Jun; 161(2):693-710.