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Nicholas G James, PhD

Title
Faculty RankAssistant Professor
InstitutionUniversity of Hawaii at Manoa
Address2500 Campus Rd
Honolulu HI 96822
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    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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    PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Zhang S, Wang H, Melick CH, Jeong MH, Curukovic A, Tiwary S, Lama-Sherpa TD, Meng D, Servage KA, James NG, Jewell JL. AKAP13 couples GPCR signaling to mTORC1 inhibition. PLoS Genet. 2021 10; 17(10):e1009832. PMID: 34673774.
      Citations: 9     Fields:    Translation:HumansAnimalsCells
    2. Tassin TC, Barylko B, Hedde PN, Chen Y, Binns DD, James NG, Mueller JD, Jameson DM, Taussig R, Albanesi JP. Gain-of-Function Properties of a Dynamin 2 Mutant Implicated in Charcot-Marie-Tooth Disease. Front Cell Neurosci. 2021; 15:745940. PMID: 34744632.
      Citations:    
    3. Meng D, Yang Q, Melick CH, Park BC, Hsieh TS, Curukovic A, Jeong MH, Zhang J, James NG, Jewell JL. ArfGAP1 inhibits mTORC1 lysosomal localization and activation. EMBO J. 2021 06 15; 40(12):e106412. PMID: 33988249.
      Citations: 11     Fields:    Translation:HumansAnimalsCells
    4. James NG, Malik S, Sanstrum BJ, Rh?aume C, Broide RS, Jameson DM, Brideau-Andersen A, Jacky BS. Characterization of clostridium botulinum neurotoxin serotype A (BoNT/A) and fibroblast growth factor receptor interactions using novel receptor dimerization assay. Sci Rep. 2021 04 09; 11(1):7832. PMID: 33837264.
      Citations: 7     Fields:    Translation:AnimalsCells
    5. Sanstrum BJ, Goo BMSS, Holden DZY, Delgado DD, Nguyen TPN, Lee KD, James NG. Fluctuation Imaging of LRRK2 Reveals that the G2019S Mutation Alters Spatial and Membrane Dynamics. Molecules. 2020 May 31; 25(11). PMID: 32486414.
      Citations:    Fields:    Translation:HumansCells
    6. Nguyen H, Ward WS, James NG. Spatial and temporal resolution of mORC4 fluorescent variants reveals structural requirements for achieving higher order self-association and pronuclei entry. Methods Appl Fluoresc. 2019 May 16; 7(3):035002. PMID: 30865939.
      Citations: 2     Fields:    Translation:AnimalsCells
    7. Gallea JI, Ambroggio EE, Vilcaes AA, James NG, Jameson DM, Celej MS. Amyloid oligomerization of the Parkinson's disease related protein a-synuclein impacts on its curvature-membrane sensitivity. J Neurochem. 2018 11; 147(4):541-556. PMID: 30142705.
      Citations: 6     Fields:    Translation:HumansCells
    8. Goo BMSS, Sanstrum BJ, Holden DZY, Yu Y, James NG. Arc/Arg3.1 has an activity-regulated interaction with PICK1 that results in altered spatial dynamics. Sci Rep. 2018 10 02; 8(1):14675. PMID: 30279480.
      Citations: 9     Fields:    Translation:AnimalsCells
    9. Barylko B, Wilkerson JR, Cavalier SH, Binns DD, James NG, Jameson DM, Huber KM, Albanesi JP. Palmitoylation and Membrane Binding of Arc/Arg3.1: A Potential Role in Synaptic Depression. Biochemistry. 2018 02 06; 57(5):520-524. PMID: 29264923.
      Citations: 26     Fields:    Translation:HumansAnimalsCells
    10. Nguyen H, James NG, Nguyen L, Nguyen TP, Vuong C, Ortega MA, Jameson DM, Ward WS. Higher Order Oligomerization of the Licensing ORC4 Protein Is Required for Polar Body Extrusion in Murine Meiosis. J Cell Biochem. 2017 09; 118(9):2941-2949. PMID: 28230328.
      Citations: 5     Fields:    Translation:AnimalsCells
    11. Berry MJ, Astern J, Bellinger F, Brampton C, Cann R, Gerschenson M, Haymer D, James NG, Jameson DM, LeSaux O, Hoffmann PR, Nichols R, Pitts M, Seale L, Seifried S, Stokes AJ, Todorovic C. Medical school hotline: the research mission of the cell and molecular biology department and program at the john a. Burns school of medicine. Hawaii J Med Public Health. 2015 Apr; 74(4):150-3. PMID: 25954603.
      Citations:    Fields:    Translation:Humans
    12. Byers CE, Barylko B, Ross JA, Southworth DR, James NG, Taylor CA, Wang L, Collins KA, Estrada A, Waung M, Tassin TC, Huber KM, Jameson DM, Albanesi JP. Enhancement of dynamin polymerization and GTPase activity by Arc/Arg3.1. Biochim Biophys Acta. 2015 Jun; 1850(6):1310-8. PMID: 25783003.
      Citations: 21     Fields:    Translation:HumansAnimalsCells
    13. Montecinos-Franjola F, James NG, Concha-Marambio L, Brunet JE, Lagos R, Monasterio O, Jameson DM. Single tryptophan mutants of FtsZ: nucleotide binding/exchange and conformational transitions. Biochim Biophys Acta. 2014 Jul; 1844(7):1193-200. PMID: 24704635.
      Citations: 5     Fields:    Translation:Cells
    14. James NG, Jameson DM. Steady-state fluorescence polarization/anisotropy for the study of protein interactions. Methods Mol Biol. 2014; 1076:29-42. PMID: 24108621.
      Citations: 10     Fields:    
    15. James NG, Digman MA, Ross JA, Barylko B, Wang L, Li J, Chen Y, Mueller JD, Gratton E, Albanesi JP, Jameson DM. A mutation associated with centronuclear myopathy enhances the size and stability of dynamin 2 complexes in cells. Biochim Biophys Acta. 2014 Jan; 1840(1):315-21. PMID: 24016602.
      Citations: 11     Fields:    Translation:HumansAnimalsCells
    16. Jameson DM, Vetromile CM, James NG. Investigations of protein-protein interactions using time-resolved fluorescence and phasors. Methods. 2013 Mar; 59(3):278-86. PMID: 23348372.
      Citations: 3     Fields:    Translation:Cells
    17. Jameson DM, James NG, Albanesi JP. Fluorescence fluctuation spectroscopy approaches to the study of receptors in live cells. Methods Enzymol. 2013; 519:87-113. PMID: 23280108.
      Citations: 5     Fields:    Translation:HumansCells
    18. James NG, Digman MA, Gratton E, Barylko B, Ding X, Albanesi JP, Goldberg MS, Jameson DM. Number and brightness analysis of LRRK2 oligomerization in live cells. Biophys J. 2012 Jun 06; 102(11):L41-3. PMID: 22713584.
      Citations: 30     Fields:    Translation:AnimalsCells
    19. Decarreau JA, James NG, Chrin LR, Berger CL. Switch I closure simultaneously promotes strong binding to actin and ADP in smooth muscle myosin. J Biol Chem. 2011 Jun 24; 286(25):22300-7. PMID: 21536675.
      Citations: 3     Fields:    Translation:AnimalsCells
    20. Gilmore MA, Williams D, Okawa Y, Holguin B, James NG, Ross JA, Roger Aoki K, Jameson DM, Steward LE. Depolarization after resonance energy transfer (DARET): a sensitive fluorescence-based assay for botulinum neurotoxin protease activity. Anal Biochem. 2011 Jun 01; 413(1):36-42. PMID: 21300022.
      Citations: 12     Fields:    Translation:Cells
    21. Stefl M, James NG, Ross JA, Jameson DM. Applications of phasors to in vitro time-resolved fluorescence measurements. Anal Biochem. 2011 Mar 01; 410(1):62-9. PMID: 21078290.
      Citations: 36     Fields:    Translation:AnimalsCells
    22. James NG, Ross JA, Stefl M, Jameson DM. Applications of phasor plots to in vitro protein studies. Anal Biochem. 2011 Mar 01; 410(1):70-6. PMID: 21078289.
      Citations: 21     Fields:    Translation:HumansCells
    23. James NG, Ross JA, Mason AB, Jameson DM. Excited-state lifetime studies of the three tryptophan residues in the N-lobe of human serum transferrin. Protein Sci. 2010 Jan; 19(1):99-110. PMID: 19916167.
      Citations: 9     Fields:    Translation:HumansCells
    24. James NG, Byrne SL, Steere AN, Smith VC, MacGillivray RT, Mason AB. Inequivalent contribution of the five tryptophan residues in the C-lobe of human serum transferrin to the fluorescence increase when iron is released. Biochemistry. 2009 Apr 07; 48(13):2858-67. PMID: 19281173.
      Citations: 12     Fields:    Translation:HumansCells
    25. Mason AB, Halbrooks PJ, James NG, Byrne SL, Grady JK, Chasteen ND, Bobst CE, Kaltashov IA, Smith VC, MacGillivray RT, Everse SJ. Structural and functional consequences of the substitution of glycine 65 with arginine in the N-lobe of human transferrin. Biochemistry. 2009 Mar 10; 48(9):1945-53. PMID: 19219998.
      Citations: 5     Fields:    Translation:HumansCells
    26. James NG, Byrne SL, Mason AB. Incorporation of 5-hydroxytryptophan into transferrin and its receptor allows assignment of the pH induced changes in intrinsic fluorescence when iron is released. Biochim Biophys Acta. 2009 Mar; 1794(3):532-40. PMID: 19103311.
      Citations: 8     Fields:    Translation:HumansCells
    27. Mason AB, Judson GL, Bravo MC, Edelstein A, Byrne SL, James NG, Roush ED, Fierke CA, Bobst CE, Kaltashov IA, Daughtery MA. Evolution reversed: the ability to bind iron restored to the N-lobe of the murine inhibitor of carbonic anhydrase by strategic mutagenesis. Biochemistry. 2008 Sep 16; 47(37):9847-55. PMID: 18712936.
      Citations: 1     Fields:    Translation:HumansAnimalsCells
    28. James NG, Mason AB. Protocol to determine accurate absorption coefficients for iron-containing transferrins. Anal Biochem. 2008 Jul 15; 378(2):202-7. PMID: 18471984.
      Citations: 16     Fields:    Translation:HumansAnimalsCells
    29. James NG, Berger CL, Byrne SL, Smith VC, MacGillivray RT, Mason AB. Intrinsic fluorescence reports a global conformational change in the N-lobe of human serum transferrin following iron release. Biochemistry. 2007 Sep 18; 46(37):10603-11. PMID: 17711300.
      Citations: 24     Fields:    Translation:HumansCells
    30. Wang F, Lothrop AP, James NG, Griffiths TA, Lambert LA, Leverence R, Kaltashov IA, Andrews NC, MacGillivray RT, Mason AB. A novel murine protein with no effect on iron homoeostasis is homologous with transferrin and is the putative inhibitor of carbonic anhydrase. Biochem J. 2007 Aug 15; 406(1):85-95. PMID: 17511619.
      Citations: 5     Fields:    Translation:HumansAnimalsCells
    31. Mason AB, Halbrooks PJ, James NG, Connolly SA, Larouche JR, Smith VC, MacGillivray RT, Chasteen ND. Mutational analysis of C-lobe ligands of human serum transferrin: insights into the mechanism of iron release. Biochemistry. 2005 Jun 07; 44(22):8013-21. PMID: 15924420.
      Citations: 23     Fields:    Translation:HumansAnimalsCells
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