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Hieu Nguyen

Title
Faculty RankJunior Researcher
InstitutionUniversity of Hawaii at Manoa
DepartmentAnatomy, Biochemistry & Physiology
AddressJohn A. Burns School of Medicine
University of Hawaii at Manoa
654 Ilalo Street
Honolulu HI 96813
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    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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    PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Tsai YT, Tseng YW, Chen YT, Nguyen HT, Lu HT, Chuang AE. Near-infrared augmented alginate-tyramine hydrogels-driven oxygen localization for osteoarthritis mitigation and cartilage repair. Int J Biol Macromol. 2025 Oct; 327(Pt 1):146949. PMID: 40829678.
      Citations:    Fields:    
    2. Chuang SC, Yu SA, Hung PC, Chuang AE, Liang JW, Rethi L, Chen CK, Fang HW, Nguyen HT, Lu HT. Corrigendum to "Transformative lactera-polypyrrole@carrageenan microparticles leveraging NIR for skin regeneration and stress relief" [Int. J. Biol. Macromol. 2025 May 20: 144436]. Int J Biol Macromol. 2025 Aug; 319(Pt 1):145949. PMID: 40695627.
      Citations:    Fields:    
    3. Hsiao CH, Lin YW, Liu CH, Chen YT, Nguyen HT, Chuang AE. Nano-orchestrated magnetotactic-like navigation for electromagnetic theranostics and immune enhancement via photoautotrophic oxygenation, mild hyperthermia, and ferroptosis. J Nanobiotechnology. 2025 Jun 13; 23(1):442. PMID: 40514659.
      Citations:    Fields:    Translation:HumansAnimalsCells
    4. Chuang SC, Yu SA, Hung PC, Chuang AE, Liang JW, Rethi L, Chen CK, Fang HW, Nguyen HT, Lu HT. Transformative lactera-polypyrrole@carrageenan microparticles leveraging NIR for skin regeneration and stress relief. Int J Biol Macromol. 2025 Jun; 316(Pt 1):144436. PMID: 40403819.
      Citations:    Fields:    Translation:HumansAnimals
    5. Chuang SC, Yu SA, Hung PC, Chuang AE, Liang JW, Sun CL, Rethi L, Fang HW, Nguyen HT, Tsai YT, Weng PW. Mitochondrial activation via calcium peroxide/carrageenan/soybean lecithin-derived polypyrrole phototherapeutic microparticles. Colloids Surf B Biointerfaces. 2025 Oct; 254:114787. PMID: 40398274.
      Citations:    Fields:    Translation:AnimalsCells
    6. Chen CK, Chiu HW, Nguyen HT, Lu HT, Chuang AE. Transdermally administered nanozymes-infused F127/methylcellulose hydrogel for osteoarthritis relief via immunomodulatory pathways. Int J Biol Macromol. 2025 Jun; 314:144114. PMID: 40354857.
      Citations:    Fields:    Translation:HumansAnimalsCells
    7. Pan WY, Weng PW, Wu SH, Hsiao CH, Jheng PR, Nguyen HN, Tseng CL, Burnouf T, Rethi L, Nguyen HT, Huang WY, Wang TJ, Chuang AE. Intranasal delivery of epigallocatechin gallate-laden platelet extracellular vesicles for mitigating retinal glaucoma. J Control Release. 2025 May 10; 381:113596. PMID: 40043911.
      Citations: 3     Fields:    Translation:HumansAnimalsCells
    8. Kelley JR, Dimitrova E, Maciuszek M, Nguyen HT, Szczurek AT, Hughes AL, Blackledge NP, Kettenbach AN, Klose RJ. The PNUTS phosphatase complex controls transcription pause release. Mol Cell. 2024 Dec 19; 84(24):4843-4861.e8. PMID: 39603239.
      Citations: 4     Fields:    Translation:HumansAnimalsCells
    9. Choy MS, Nguyen HT, Kumar GS, Peti W, Kettenbach AN, Page R. A protein phosphatase 1 specific phosphatase targeting peptide (PhosTAP) to identify the PP1 phosphatome. Proc Natl Acad Sci U S A. 2024 Oct 29; 121(44):e2415383121. PMID: 39446389.
      Citations: 4     Fields:    Translation:HumansCells
    10. Weng PW, Lu HT, Rethi L, Liu CH, Wong CC, Rethi L, Wu KC, Jheng PR, Nguyen HT, Chuang AE. Alleviating rheumatoid arthritis with a photo-pharmacotherapeutic glycan-integrated nanogel complex for advanced percutaneous delivery. J Nanobiotechnology. 2024 Oct 21; 22(1):646. PMID: 39428483.
      Citations:    Fields:    Translation:Animals
    11. Roychowdhury T, McNutt SW, Pasala C, Nguyen HT, Thornton DT, Sharma S, Botticelli L, Digwal CS, Joshi S, Yang N, Panchal P, Chakrabarty S, Bay S, Markov V, Kwong C, Lisanti J, Chung SY, Ginsberg SD, Yan P, De Stanchina E, Corben A, Modi S, Alpaugh ML, Colombo G, Erdjument-Bromage H, Neubert TA, Chalkley RJ, Baker PR, Burlingame AL, Rodina A, Chiosis G, Chu F. Phosphorylation-driven epichaperome assembly is a regulator of cellular adaptability and proliferation. Nat Commun. 2024 10 16; 15(1):8912. PMID: 39414766.
      Citations: 9     Fields:    Translation:HumansAnimalsCells
    12. Wang Y, Lin R, Liu C, Wang X, Chosy C, Haruta Y, Bui AD, Li M, Sun H, Zheng X, Luo H, Wu P, Gao H, Sun W, Nie Y, Zhu H, Zhou K, Nguyen HT, Luo X, Li L, Xiao C, Saidaminov MI, Stranks SD, Zhang L, Tan H. Homogenized contact in all-perovskite tandems using tailored 2D perovskite. Nature. 2024 Nov; 635(8040):867-873. PMID: 39401514.
      Citations: 15     Fields:    
    13. Chuang AE, Chen YL, Chiu HJ, Nguyen HT, Liu CH. Nasal administration of polysaccharides-based nanocarrier combining hemoglobin and diferuloylmethane for managing diabetic kidney disease. Int J Biol Macromol. 2024 Dec; 282(Pt 1):136534. PMID: 39406330.
      Citations: 1     Fields:    Translation:HumansAnimals
    14. Hsiao CH, Lin YW, Liu CH, Nguyen HT, Chuang AE. Light-Driven Green-Fabricated Artificial Intelligence-Enabled Micro/Nanorobots for Multimodal Phototherapeutic Management of Bladder Cancer. Adv Healthc Mater. 2024 12; 13(32):e2402864. PMID: 39344248.
      Citations: 1     Fields:    Translation:HumansAnimalsCells
    15. Chuang AE, Tao YK, Dong SW, Nguyen HT, Liu CH. Polypyrrole/iron-glycol chitosan nanozymes mediate M1 macrophages to enhance the X-ray-triggered photodynamic therapy for bladder cancer by promoting antitumor immunity. Int J Biol Macromol. 2024 Nov; 280(Pt 4):135608. PMID: 39276877.
      Citations: 1     Fields:    Translation:HumansAnimalsCells
    16. Chuang AE, Chen YL, Nguyen HT, Lu HT, Liu CH. Sequential management of burn wound healing stages through biointelligence-inspired platelet extracellular vesicle-encapsulated photodynamic diferuloylmethane. Nanoscale. 2024 Aug 29; 16(34):16089-16106. PMID: 39092551.
      Citations: 1     Fields:    Translation:HumansAnimalsCells
    17. Chiang CC, Liu CH, Rethi L, Nguyen HT, Chuang AE. Phototactic/Photosynthetic/Magnetic-Powered Chlamydomonas Reinhardtii-Metal-Organic Frameworks Micro/Nanomotors for Intelligent Thrombolytic Management and Ischemia Alleviation. Adv Healthc Mater. 2024 11; 13(29):e2401383. PMID: 39155411.
      Citations: 1     Fields:    Translation:HumansAnimalsCells
    18. Wu H, Nguyen H, Hashim PH, Fogelgren B, Duncan FE, Ward WS. Oocyte-specific EXOC5 expression is required for mouse oogenesis and folliculogenesis. Mol Hum Reprod. 2024 Aug 05; 30(8). PMID: 39037927.
      Citations: 2     Fields:    Translation:AnimalsCells
    19. Chuang AE, Lin YW, Jheng PR, Rethi L, Nguyen HT, Weng PW. Bio-intelligent plasma-engineered diferuloylmethane/fucoidan/neutrophil lysate/iron oxide nanoclusters for phototherapeutic and magnetotherapeutic with in situ magnetic gelation mitigating inflammatory diseases. Colloids Surf B Biointerfaces. 2024 Nov; 243:114054. PMID: 39079188.
      Citations:    Fields:    Translation:HumansAnimalsCells
    20. Tao YK, Tseng YW, Tzou KY, Kuo CY, Nguyen HT, Lu HT, Chuang AE. Advancing teeth whitening efficacy via dual-phototherapeutic strategy incorporating molybdenum disulfide embedded in carrageenan hydrogel for dental healthcare. Int J Biol Macromol. 2024 Sep; 276(Pt 1):133647. PMID: 38964693.
      Citations: 2     Fields:    Translation:HumansAnimals
    21. Wang TJ, Rethi L, Ku MY, Nguyen HT, Chuang AE. A review on revolutionizing ophthalmic therapy: Unveiling the potential of chitosan, hyaluronic acid, cellulose, cyclodextrin, and poloxamer in eye disease treatments. Int J Biol Macromol. 2024 Jul; 273(Pt 2):132700. PMID: 38879998.
      Citations: 8     Fields:    Translation:HumansAnimals
    22. McNutt SW, Roychowdhury T, Pasala C, Nguyen HT, Thornton DT, Sharma S, Botticelli L, Digwal CS, Joshi S, Yang N, Panchal P, Chakrabarty S, Bay S, Markov V, Kwong C, Lisanti J, Chung SY, Ginsberg SD, Yan P, DeStanchina E, Corben A, Modi S, Alpaugh M, Colombo G, Erdjument-Bromage H, Neubert TA, Chalkley RJ, Baker PR, Burlingame AL, Rodina A, Chiosis G, Chu F. Phosphorylation-Driven Epichaperome Assembly: A Critical Regulator of Cellular Adaptability and Proliferation. Res Sq. 2024 Apr 03. PMID: 38645031.
      Citations:    
    23. Wu SH, Rethi L, Pan WY, Nguyen HT, Chuang AE. Emerging horizons and prospects of polysaccharide-constructed gels in the realm of wound healing. Colloids Surf B Biointerfaces. 2024 Mar; 235:113759. PMID: 38280240.
      Citations: 2     Fields:    
    24. Nguyen H, Ribas-Maynou J, Wu H, Quon B, Inouye T, Walker B, Langaman C, Huang TTF, Ward WS. Low levels of mouse sperm chromatin fragmentation delay embryo development. Biol Reprod. 2023 11 15; 109(5):635-643. PMID: 37658763.
      Citations: 5     Fields:    Translation:AnimalsCells
    25. Hein JB, Nguyen HT, Garvanska DH, Nasa I, Kruse T, Feng Y, Lopez Mendez B, Davey N, Kettenbach AN, Fordyce PM, Nilsson J. Phosphatase specificity principles uncovered by MRBLE:Dephos and global substrate identification. Mol Syst Biol. 2023 12 06; 19(12):e11782. PMID: 37916966.
      Citations: 11     Fields:    Translation:Cells
    26. Liu CH, Jheng PR, Rethi L, Godugu C, Lee CY, Chen YT, Nguyen HT, Chuang EY. P-Selectin mediates targeting of a self-assembling phototherapeutic nanovehicle enclosing dipyridamole for managing thromboses. J Nanobiotechnology. 2023 Aug 08; 21(1):260. PMID: 37553670.
      Citations: 6     Fields:    Translation:Animals
    27. Liu CH, Liu MC, Jheng PR, Yu J, Fan YJ, Liang JW, Hsiao YC, Chiang CW, Bolouki N, Lee JW, Hsieh JH, Mansel BW, Chen YT, Nguyen HT, Chuang EY. Plasma-Derived Nanoclusters for Site-Specific Multimodality Photo/Magnetic Thrombus Theranostics. Adv Healthc Mater. 2023 11; 12(28):e2301504. PMID: 37421244.
      Citations: 5     Fields:    Translation:Animals
    28. Nguyen HT, Vasconcellos HD, Keck K, Reis JP, Lewis CE, Sidney S, Lloyd-Jones DM, Schreiner PJ, Guallar E, Wu CO, Lima JAC, Ambale-Venkatesh B. Multivariate longitudinal data for survival analysis of cardiovascular event prediction in young adults: insights from a comparative explainable study. BMC Med Res Methodol. 2023 01 25; 23(1):23. PMID: 36698064.
      Citations: 3     Fields:    Translation:Humans
    29. Nguyen H, Wu H, Ung A, Yamazaki Y, Fogelgren B, Ward WS. Deletion of Orc4 during oogenesis severely reduces polar body extrusion and blocks zygotic DNA replication?. Biol Reprod. 2022 04 26; 106(4):730-740. PMID: 34977916.
      Citations: 3     Fields:    Translation:Cells
    30. Swartz SZ, Nguyen HT, McEwan BC, Adamo ME, Cheeseman IM, Kettenbach AN. Selective dephosphorylation by PP2A-B55 directs the meiosis I-meiosis II transition in oocytes. Elife. 2021 08 03; 10. PMID: 34342579.
      Citations: 11     Fields:    Translation:AnimalsCells
    31. Nguyen HT, Ho TL, Pratomo A, Ilsan NA, Huang TW, Chen CH, Chuang EY. Enzymatically triggered graphene oxide released from multifunctional carriers boosts anti-pathogenic properties for promising wound-healing applications. Mater Sci Eng C Mater Biol Appl. 2021 Sep; 128:112265. PMID: 34474824.
      Citations: 5     Fields:    Translation:Humans
    32. Hsiao YC, Jheng PR, Nguyen HT, Chen YH, Manga YB, Lu LS, Rethi L, Chen CH, Huang TW, Lin JD, Chang TK, Ho YC, Chuang EY. Photothermal-Irradiated Polyethyleneimine-Polypyrrole Nanopigment Film-Coated Polyethylene Fabrics for Infrared-Inspired with Pathogenic Evaluation. ACS Appl Mater Interfaces. 2021 Jan 20; 13(2):2483-2495. PMID: 33404219.
      Citations: 9     Fields:    Translation:AnimalsCells
    33. Nguyen H, Ung A, Ward WS. The role of ORC4 in enucleation of Murine Erythroleukemia (MEL) cells is similar to that in oocyte polar body extrusion. Syst Biol Reprod Med. 2020 Dec; 66(6):378-386. PMID: 32972244.
      Citations: 3     Fields:    Translation:AnimalsCells
    34. Han Z, Margulies SL, Kurian D, Jabaut JM, Mehta A, Dudum R, Koudoro H, Roberts RS, Lee J, Li J, Nguyen HT, Elliott M. Engaging medical students in problem-based search and study of the biomedical literature. Int J Med Educ. 2017 Aug 17; 8:297-299. PMID: 28829332.
      Citations: 1     Fields:    Translation:Humans
    35. Nguyen H, James NG, Nguyen L, Nguyen TP, Vuong C, Ortega MA, Jameson DM, Ward WS. Higher Order Oligomerization of the Licensing ORC4 Protein Is Required for Polar Body Extrusion in Murine Meiosis. J Cell Biochem. 2017 09; 118(9):2941-2949. PMID: 28230328.
      Citations: 5     Fields:    Translation:AnimalsCells
    36. Nguyen HT, Umemura K, Kawano T. Indole-3-acetic acid-induced oxidative burst and an increase in cytosolic calcium ion concentration in rice suspension culture. Biosci Biotechnol Biochem. 2016 Aug; 80(8):1546-54. PMID: 27149194.
      Citations: 5     Fields:    Translation:AnimalsCells
    37. Ortega MA, Nguyen H, Ward WS. ORC proteins in the mammalian zygote. Cell Tissue Res. 2016 Jan; 363(1):195-200. PMID: 26453397.
      Citations: 8     Fields:    Translation:HumansAnimalsCells
    38. Nguyen H, Ortega MA, Ko M, Marh J, Ward WS. ORC4 surrounds extruded chromatin in female meiosis. J Cell Biochem. 2015 May; 116(5):778-86. PMID: 25502171.
      Citations: 11     Fields:    Translation:AnimalsCells
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