Chromatin

"Chromatin" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure, which enables searching at various levels of specificity.

MeSH information

Definition | Details | More General Concepts | Related Concepts | More Specific Concepts

The material of CHROMOSOMES. It is a complex of DNA; HISTONES; and nonhistone proteins (CHROMOSOMAL PROTEINS, NON-HISTONE) found within the nucleus of a cell.

Descriptor ID	D002843
MeSH Number(s)	A11.284.430.106.279.345.190.160.180 D12.776.664.224 G05.360.160.180
Concept/Terms	Chromatin Chromatin Chromatins

Below are MeSH descriptors whose meaning is more general than "Chromatin".

Anatomy [A]
Cells [A11]
Cellular Structures [A11.284]
Intracellular Space [A11.284.430]
Cell Nucleus [A11.284.430.106]
Cell Nucleus Structures [A11.284.430.106.279]
Intranuclear Space [A11.284.430.106.279.345]
Chromosomes [A11.284.430.106.279.345.190]
Chromosome Structures [A11.284.430.106.279.345.190.160]
Chromatin [A11.284.430.106.279.345.190.160.180]
Chemicals and Drugs [D]
Amino Acids, Peptides, and Proteins [D12]
Proteins [D12.776]
Nucleoproteins [D12.776.664]
Chromatin [D12.776.664.224]
Biological Sciences [G]
Genetic Phenomena [G05]
Genetic Structures [G05.360]
Chromosome Structures [G05.360.160]
Chromatin [G05.360.160.180]

Below are MeSH descriptors whose meaning is related to "Chromatin".

Below are MeSH descriptors whose meaning is more specific than "Chromatin".

publications

Timeline | Most Recent

This graph shows the total number of publications written about "Chromatin" by people in this website by year, and whether "Chromatin" was a major or minor topic of these publications.

Bar chart showing 141 publications over 27 distinct years, with a maximum of 11 publications in 2015

To see the data from this visualization as text, click here.

Year	Major Topic	Minor Topic	Total
1996	3	1	4
1998	1	0	1
2000	2	0	2
2002	0	1	1
2003	1	3	4
2004	4	6	10
2005	3	4	7
2006	4	4	8
2007	2	6	8
2008	4	1	5
2009	2	3	5
2010	1	5	6
2011	3	6	9
2012	1	4	5
2013	2	6	8
2014	0	3	3
2015	5	6	11
2016	0	3	3
2017	2	2	4
2018	4	3	7
2019	1	1	2
2020	2	1	3
2021	2	1	3
2022	2	5	7
2023	3	4	7
2024	3	2	5
2025	2	1	3

Below are the most recent publications written about "Chromatin" by people in Profiles.

Ellison V, Polotskaia A, Xiao G, Leybengrub P, Lee R, Qiu W, Hendrickson RC, Hu W, Bargonetti J. A cancer persistent DNA repair circuit driven by MDM2, MDM4 (MDMX), and mutant p53 for recruitment of MDC1 and 53BP1 on chromatin. Nucleic Acids Res. 2025 Jul 08; 53(13).

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Sapp N, Prakash P, Chakraborty R, Balasubramaniam M, Dash C. The role of chromatin in retroviral preintegration complex function. J Biol Chem. 2025 08; 301(8):110440.

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Gemeinhardt TM, Regy RM, Phan TM, Pal N, Sharma J, Senkovich O, Mendiola AJ, Ledterman HJ, Henrickson A, Lopes D, Kapoor U, Bihani A, Sihou D, Kim YC, Jeruzalmi D, Demeler B, Kim CA, Mittal J, Francis NJ. A disordered linker in the Polycomb protein Polyhomeotic tunes phase separation and oligomerization. Mol Cell. 2025 Jun 05; 85(11):2128-2146.e15.

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Beigel K, Wang XM, Song L, Maurer K, Breen C, Taylor D, Goldman D, Petri M, Sullivan KE. Comparison of cell type and disease subset chromatin modifications in SLE. Clin Epigenetics. 2024 Nov 14; 16(1):159.

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Ejaz U, Dou Z, Yao PY, Wang Z, Liu X, Yao X. Chromothripsis: an emerging crossroad from aberrant mitosis to therapeutic opportunities. J Mol Cell Biol. 2024 09 30; 16(4).

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Williams J, Regedanz E, Lucinda N, Nava Fereira AR, Lacatus G, Berger M, O'Connell N, Coursey T, Ruan J, Bisaro DM, Sunter G. Mutation of the conserved late element in geminivirus CP promoters abolishes Arabidopsis TCP24 transcription factor binding and decreases H3K27me3 levels on viral chromatin. PLoS Pathog. 2024 Jul; 20(7):e1012399.

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Bharti R, Dey G, Khan D, Myers A, Huffman OG, Saygin C, Braley C, Richards E, Sangwan N, Willard B, Lathia JD, Fox PL, Lin F, Jha BK, Brown JM, Yu JS, Dwidar M, Joehlin-Price A, Vargas R, Michener CM, Longworth MS, Reizes O. Cell surface CD55 traffics to the nucleus leading to cisplatin resistance and stemness by inducing PRC2 and H3K27 trimethylation on chromatin in ovarian cancer. Mol Cancer. 2024 Jun 10; 23(1):121.

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Chen Y, Gao Z, Mohd-Ibrahim I, Yang H, Wu L, Fu Y, Deng Y. Pan-cancer analyses of bromodomain containing 9 as a novel therapeutic target reveals its diagnostic, prognostic potential and biological mechanism in human tumours. Clin Transl Med. 2024 02; 14(2):e1543.

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Zhou F, Tan P, Liu S, Chang L, Yang J, Sun M, Guo Y, Si Y, Wang D, Yu J, Ma Y. Subcellular RNA distribution and its change during human embryonic stem cell differentiation. Stem Cell Reports. 2024 01 09; 19(1):126-140.

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Nguyen H, Ribas-Maynou J, Wu H, Quon B, Inouye T, Walker B, Langaman C, Huang TTF, Ward WS. Low levels of mouse sperm chromatin fragmentation delay embryo development. Biol Reprod. 2023 11 15; 109(5):635-643.

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