T-Lymphocytes

"T-Lymphocytes" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure, which enables searching at various levels of specificity.

MeSH information

Definition | Details | More General Concepts | Related Concepts | More Specific Concepts

Lymphocytes responsible for cell-mediated immunity. Two types have been identified - cytotoxic (T-LYMPHOCYTES, CYTOTOXIC) and helper T-lymphocytes (T-LYMPHOCYTES, HELPER-INDUCER). They are formed when lymphocytes circulate through the THYMUS GLAND and differentiate to thymocytes. When exposed to an antigen, they divide rapidly and produce large numbers of new T cells sensitized to that antigen.

Descriptor ID	D013601
MeSH Number(s)	A11.118.637.555.567.569 A15.145.229.637.555.567.569 A15.382.490.555.567.569
Concept/Terms	T-Lymphocytes T-Lymphocytes T Lymphocytes T-Lymphocyte T-Cells T Cells T-Cell Thymus-Dependent Lymphocytes Lymphocyte, Thymus-Dependent Lymphocytes, Thymus-Dependent Thymus Dependent Lymphocytes Thymus-Dependent Lymphocyte

Below are MeSH descriptors whose meaning is more general than "T-Lymphocytes".

Anatomy [A]
Cells [A11]
Blood Cells [A11.118]
Leukocytes [A11.118.637]
Leukocytes, Mononuclear [A11.118.637.555]
Lymphocytes [A11.118.637.555.567]
T-Lymphocytes [A11.118.637.555.567.569]
Hemic and Immune Systems [A15]
Blood [A15.145]
Blood Cells [A15.145.229]
Leukocytes [A15.145.229.637]
Leukocytes, Mononuclear [A15.145.229.637.555]
Lymphocytes [A15.145.229.637.555.567]
T-Lymphocytes [A15.145.229.637.555.567.569]
Immune System [A15.382]
Leukocytes [A15.382.490]
Leukocytes, Mononuclear [A15.382.490.555]
Lymphocytes [A15.382.490.555.567]
T-Lymphocytes [A15.382.490.555.567.569]

Below are MeSH descriptors whose meaning is related to "T-Lymphocytes".

Below are MeSH descriptors whose meaning is more specific than "T-Lymphocytes".

publications

Timeline | Most Recent

This graph shows the total number of publications written about "T-Lymphocytes" by people in this website by year, and whether "T-Lymphocytes" was a major or minor topic of these publications.

Bar chart showing 284 publications over 30 distinct years, with a maximum of 19 publications in 2001

To see the data from this visualization as text, click here.

Year	Major Topic	Minor Topic	Total
1996	3	2	5
1997	4	1	5
1998	5	5	10
1999	4	1	5
2000	7	5	12
2001	10	9	19
2002	6	4	10
2003	5	9	14
2004	8	4	12
2005	2	4	6
2006	6	4	10
2007	6	5	11
2008	6	6	12
2009	2	7	9
2010	6	2	8
2011	8	9	17
2012	6	3	9
2013	7	4	11
2014	4	6	10
2015	8	5	13
2016	5	4	9
2017	4	4	8
2018	3	4	7
2019	6	2	8
2020	5	4	9
2021	5	8	13
2022	2	3	5
2023	1	4	5
2024	4	4	8
2025	1	3	4

Below are the most recent publications written about "T-Lymphocytes" by people in Profiles.

Lau LS, Suarez M, Fernandez B, Souchak J, Antonopoulos A, Hu N, Abreu MM, Koehne G, Dell A, Haslam SM, Posey AD, Dimitroff CJ. Glycoengineering CAR-T cells to overcome galectin-3-mediated immunosuppression. Front Immunol. 2026; 17:1766555.

View in: PubMed
Tanji Y, Shimada S, Kato M, Akiyama Y, Hatano M, Tsukihara S, Igarashi Y, Kodera K, Okazaki K, Yasukawa K, Umemura K, Kamachi A, Nara A, Yamane M, Ishikawa Y, Mochizuki E, Mochida Y, Ikegami T, Ban D, Uchida S, Tanaka S. Cytokine mRNA-based therapy alleviates dendritic cell and T cell paucity to eliminate aggressive pancreatic cancer in preclinical mouse models. EBioMedicine. 2026 Mar; 125:106137.

View in: PubMed
Xiong Z, Kong Q, Chagantipati B, Stepniak A, Jaswal AP, Sneiderman CT, Han Y, Jackson SA, Raphael RA, Zhang W, Li M, Chao Y, Qin B, Dulkadir Z, Schwegman L, Zhang Y, Kuminkoski C, Mahlke MA, Nath P, Hu B, Zinn PO, Mantica M, Agnihotri S, Nechemia-Arbely Y, Pollack IF, Rigatti LH, Forsthuber TG, Li X, Raphael I, Kohanbash G. C/EBP?-induced alternative splicing of RCAN1 generates a potent TCR-T target in mesenchymal glioblastoma. Cell Mol Immunol. 2026 Jan; 23(1):94-113.

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Landry LG, Wells KL, Anderson AM, Miller KR, Jones KL, Michels AW, Nakayama M. Quantitative V gene-targeted T cell receptor sequencing as a biomarker in type 1 diabetes. JCI Insight. 2026 Feb 09; 11(3).

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Pirillo E, Freenor V F, Wamba BEN, Bhatnagar S, Mondal T, Tushir-Singh J. An evolutionary T119R substitution in the macaque T-cell immunoreceptor TIGIT enables proteolytic shedding and reveals clinical antibody vulnerabilities. J Biol Chem. 2026 01; 302(1):110962.

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Beigel K, Alsaati N, Maurer K, McDonald-McGinn D, Crowley TB, Knight M, Henrickson SE, Bassett AS, Sullivan KE. Single cell RNA-seq analysis of hematopoietic cell types in 22q11.2 deletion syndrome reveals significant changes to non-T cells. Pediatr Allergy Immunol. 2025 11; 36(11):e70237.

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Cervantes JA, Welch TP, Kaiser B, Bill CA, Torres A, Bill GL, Bill CA, Vines CM. Signaling via C-C Chemokine Ligand 19 and Extracellular Regulated Kinase 5 in T Cells Limits the Humoral Adaptive Immune Response in Mice. Int J Mol Sci. 2025 Oct 07; 26(19).

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Wamba BEN, Mondal T, Freenor V F, Shaheed M, Pang O, Bedinger D, Legembre P, Devel L, Bhatnagar S, Leiserowitz GS, Tushir-Singh J. Evolutionary regulation of human Fas ligand (CD95L) by plasmin in solid cancer immunotherapy. Nat Commun. 2025 Jul 01; 16(1):5748.

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Coleman MI, Khan MB, Gbodossou E, Diop A, DeBarros K, Bond VC, Floyd V, Kondwani K, Rice VM, Powell MD. Plant Lectin, MoMo30, Pressures HIV-1 to Select for Variants with Deleted N-Linked Glycosylation Sites. Viruses. 2025 06 27; 17(7).

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Xiong Z, Sneiderman CT, Kuminkoski CR, Reinheimer J, Schwegman L, Sever RE, Habib A, Hu B, Agnihotri S, Rajasundaram D, Zinn PO, Forsthuber TG, Pollack IF, Li X, Raphael I, Kohanbash G. Transcript-targeted antigen mapping reveals the potential of POSTN splicing junction epitopes in glioblastoma immunotherapy. Genes Immun. 2025 06; 26(3):190-199.

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