Common Variable Immunodeficiency

"Common Variable Immunodeficiency" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure, which enables searching at various levels of specificity.

MeSH information

Definition | Details | More General Concepts | Related Concepts | More Specific Concepts

Heterogeneous group of immunodeficiency syndromes characterized by hypogammaglobulinemia of most isotypes, variable B-cell defects, and the presence of recurrent bacterial infections.

Descriptor ID	D017074
MeSH Number(s)	C20.673.330
Concept/Terms	Common Variable Immunodeficiency Common Variable Immunodeficiency Common Variable Immunodeficiencies Immunodeficiencies, Common Variable Immunodeficiency, Common Variable Common Variable Hypogammaglobulinemia Common Variable Hypogammaglobulinemias Hypogammaglobulinemia, Common Variable Hypogammaglobulinemias, Common Variable Variable Hypogammaglobulinemia, Common Variable Hypogammaglobulinemias, Common Common Variable Immune Deficiency Hypogammaglobulinemia, Acquired Hypogammaglobulinemia, Acquired Acquired Hypogammaglobulinemia Acquired Hypogammaglobulinemias Hypogammaglobulinemias, Acquired Immunoglobulin Deficiency, Late-Onset Immunoglobulin Deficiency, Late-Onset Deficiencies, Late-Onset Immunoglobulin Deficiency, Late-Onset Immunoglobulin Immunoglobulin Deficiencies, Late-Onset Immunoglobulin Deficiency, Late Onset Late-Onset Immunoglobulin Deficiencies Late-Onset Immunoglobulin Deficiency

Below are MeSH descriptors whose meaning is more general than "Common Variable Immunodeficiency".

Diseases [C]
Immune System Diseases [C20]
Immunologic Deficiency Syndromes [C20.673]
Common Variable Immunodeficiency [C20.673.330]

Below are MeSH descriptors whose meaning is related to "Common Variable Immunodeficiency".

Below are MeSH descriptors whose meaning is more specific than "Common Variable Immunodeficiency".

publications

Timeline | Most Recent

This graph shows the total number of publications written about "Common Variable Immunodeficiency" by people in this website by year, and whether "Common Variable Immunodeficiency" was a major or minor topic of these publications.

Bar chart showing 28 publications over 17 distinct years, with a maximum of 5 publications in 2015

To see the data from this visualization as text, click here.

Year	Major Topic	Minor Topic	Total
1997	1	0	1
2002	0	1	1
2005	1	0	1
2006	1	0	1
2009	1	0	1
2010	1	0	1
2011	1	0	1
2013	1	0	1
2014	1	0	1
2015	5	0	5
2016	1	0	1
2017	2	0	2
2018	4	0	4
2019	2	0	2
2020	2	0	2
2022	1	0	1
2023	2	0	2

Below are the most recent publications written about "Common Variable Immunodeficiency" by people in Profiles.

Malik S, Jeanpierre L, Cianferoni A, Ruffner M, Sullivan KE. A patient with Pitt-Hopkins syndrome with concomitant common variable immunodeficiency. Am J Med Genet A. 2024 Apr; 194(4):e63490.

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Correa-Jimenez O, Restrepo-Gualteros S, Nino G, Cunningham-Rundles C, Sullivan KE, Fuleihan RL, Gutierrez MJ. Respiratory Comorbidities Associated with Bronchiectasis in Patients with Common Variable Immunodeficiency in the USIDNET Registry. J Clin Immunol. 2023 11; 43(8):2208-2220.

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Syed MN, Kutac C, Miller JM, Marsh R, Sullivan KE, Cunningham-Rundles C, Fuleihan RL, Kheradmand F, Hajjar J. Risk Factors of Pneumonia in Primary Antibody Deficiency Patients Receiving Immunoglobulin Therapy: Data from the US Immunodeficiency Network (USIDNET). J Clin Immunol. 2022 10; 42(7):1545-1552.

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Zhang S, Kline M, Fuleihan RL, Consortium U, Scalchunes C, Sullivan KE, Jongco AM. PROMIS-29 survey confirms major impact of fatigue on health-related quality of life in common variable immunodeficiency. Immunol Res. 2020 12; 68(6):379-388.

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Yakaboski E, Fuleihan RL, Sullivan KE, Cunningham-Rundles C, Feuille E. Lymphoproliferative Disease in CVID: a Report of Types and Frequencies from a US Patient Registry. J Clin Immunol. 2020 04; 40(3):524-530.

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Lee WI, Fan WL, Lu CH, Chen SH, Kuo ML, Lin SJ, Tsai WS, Jaing TH, Chen LC, Yeh KW, Yao TC, Huang JL. A Novel CD3G Mutation in a Taiwanese Patient With Normal T Regulatory Function Presenting With the CVID Phenotype Free of Autoimmunity-Analysis of all Genotypes and Phenotypes. Front Immunol. 2019; 10:2833.

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Le Coz C, Bengsch B, Khanna C, Trofa M, Ohtani T, Nolan BE, Henrickson SE, Lambert MP, Kim TO, Despotovic JM, Feldman S, Fadugba OO, Takach P, Ruffner M, Jyonouchi S, Heimall J, Sullivan KE, Wherry EJ, Romberg N. Common variable immunodeficiency-associated endotoxemia promotes early commitment to the T follicular lineage. J Allergy Clin Immunol. 2019 12; 144(6):1660-1673.

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Sullivan KE. Neutropenia as a sign of immunodeficiency. J Allergy Clin Immunol. 2019 01; 143(1):96-100.

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Romberg N, Le Coz C, Glauzy S, Schickel JN, Trofa M, Nolan BE, Paessler M, Xu ML, Lambert MP, Lakhani SA, Khokha MK, Jyonouchi S, Heimall J, Takach P, Maglione PJ, Catanzaro J, Hsu FI, Sullivan KE, Cunningham-Rundles C, Meffre E. Patients with common variable immunodeficiency with autoimmune cytopenias exhibit hyperplastic yet inefficient germinal center responses. J Allergy Clin Immunol. 2019 01; 143(1):258-265.

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Gutierrez MJ, Sullivan KE, Fuleihan R, Bingham CO. Phenotypic characterization of patients with rheumatologic manifestations of common variable immunodeficiency. Semin Arthritis Rheum. 2018 10; 48(2):318-326.

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