Natural Killer T-Cells

"Natural Killer T-Cells" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure, which enables searching at various levels of specificity.

MeSH information

Definition | Details | More General Concepts | Related Concepts | More Specific Concepts

A specialized subset of T-LYMPHOCYTES that exhibit features of INNATE IMMUNITY similar to that of NATURAL KILLER CELLS. They are reactive to glycolipids presented in the context of the major histocompatibility complex (MHC) class I-like molecule, CD1D ANTIGEN.

Descriptor ID	D055611
MeSH Number(s)	A11.118.637.555.567.569.290 A15.145.229.637.555.567.569.360 A15.382.490.555.567.569.470
Concept/Terms	Natural Killer T-Cells Natural Killer T-Cells Killer T-Cell, Natural Killer T-Cells, Natural Natural Killer T Cells T-Cell, Natural Killer T-Cells, Natural Killer NKT Cells Natural Killer T-Cell Natural Killer T Cell NKT Cell Invariant Natural Killer T-Cells Invariant Natural Killer T-Cells Invariant Natural Killer T Cells iNKT Cells Cell, iNKT Cells, iNKT iNKT Cell

Below are MeSH descriptors whose meaning is more general than "Natural Killer T-Cells".

Anatomy [A]
Cells [A11]
Blood Cells [A11.118]
Leukocytes [A11.118.637]
Leukocytes, Mononuclear [A11.118.637.555]
Lymphocytes [A11.118.637.555.567]
T-Lymphocytes [A11.118.637.555.567.569]
Natural Killer T-Cells [A11.118.637.555.567.569.290]
Hemic and Immune Systems [A15]
Blood [A15.145]
Blood Cells [A15.145.229]
Leukocytes [A15.145.229.637]
Leukocytes, Mononuclear [A15.145.229.637.555]
Lymphocytes [A15.145.229.637.555.567]
T-Lymphocytes [A15.145.229.637.555.567.569]
Natural Killer T-Cells [A15.145.229.637.555.567.569.360]
Immune System [A15.382]
Leukocytes [A15.382.490]
Leukocytes, Mononuclear [A15.382.490.555]
Lymphocytes [A15.382.490.555.567]
T-Lymphocytes [A15.382.490.555.567.569]
Natural Killer T-Cells [A15.382.490.555.567.569.470]

Below are MeSH descriptors whose meaning is related to "Natural Killer T-Cells".

Below are MeSH descriptors whose meaning is more specific than "Natural Killer T-Cells".

publications

Timeline | Most Recent

This graph shows the total number of publications written about "Natural Killer T-Cells" by people in this website by year, and whether "Natural Killer T-Cells" was a major or minor topic of these publications.

Bar chart showing 11 publications over 8 distinct years, with a maximum of 2 publications in 2009 and 2011 and 2017

To see the data from this visualization as text, click here.

Year	Major Topic	Minor Topic	Total
2009	2	0	2
2010	1	0	1
2011	1	1	2
2015	0	1	1
2016	0	1	1
2017	1	1	2
2021	1	0	1
2022	1	0	1

Below are the most recent publications written about "Natural Killer T-Cells" by people in Profiles.

D?vila Salda?a BJ, John T, Bonifant C, Buchbinder D, Chandra S, Chandrakasan S, Chang W, Chen L, Elfassy HL, Geerlinks AV, Giller RH, Goyal R, Hagin D, Islam S, Mallhi K, Miller HK, Owen W, Pacheco M, Patel NC, Querfeld C, Quigg T, Richard N, Schiff D, Shereck E, Stenger E, Jordan MB, Heslop HE, Bollard CM, Cohen JI. High risk of relapsed disease in patients with NK/T-cell chronic active Epstein-Barr virus disease outside of Asia. Blood Adv. 2022 01 25; 6(2):452-459.

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Shute T, Amiel E, Alam N, Yates JL, Mohrs K, Dudley E, Salas B, Mesa C, Serrata A, Angel D, Vincent BK, Weyers A, Lanthier PA, Vomhof-Dekrey E, Fromme R, Laughlin M, Durham O, Miao J, Shipp D, Linhardt RJ, Nash K, Leadbetter EA. Glycolipid-Containing Nanoparticle Vaccine Engages Invariant NKT Cells to Enhance Humoral Protection against Systemic Bacterial Infection but Abrogates T-Independent Vaccine Responses. J Immunol. 2021 04 15; 206(8):1806-1816.

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Li X, Huang J, Kawamura A, Funakoshi R, Porcelli SA, Tsuji M. Co-localization of a CD1d-binding glycolipid with an adenovirus-based malaria vaccine for a potent adjuvant effect. Vaccine. 2017 05 31; 35(24):3171-3177.

View in: PubMed
Shanker A, Thounaojam MC, Mishra MK, Dikov MM. Innate-Adaptive Immune Crosstalk 2016. J Immunol Res. 2017; 2017:3503207.

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Lee WJ, Lee MH, Won CH, Chang SE, Choi JH, Moon KC, Park CS, Lee MW. Comparative histopathologic analysis of cutaneous extranodal natural killer/T-cell lymphomas according to their clinical morphology. J Cutan Pathol. 2016 Apr; 43(4):324-33.

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Li X, Kawamura A, Andrews CD, Miller JL, Wu D, Tsao T, Zhang M, Oren D, Padte NN, Porcelli SA, Wong CH, Kappe SH, Ho DD, Tsuji M. Colocalization of a CD1d-Binding Glycolipid with a Radiation-Attenuated Sporozoite Vaccine in Lymph Node-Resident Dendritic Cells for a Robust Adjuvant Effect. J Immunol. 2015 Sep 15; 195(6):2710-21.

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Gordy LE, Bezbradica JS, Flyak AI, Spencer CT, Dunkle A, Sun J, Stanic AK, Boothby MR, He YW, Zhao Z, Van Kaer L, Joyce S. IL-15 regulates homeostasis and terminal maturation of NKT cells. J Immunol. 2011 Dec 15; 187(12):6335-45.

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Ghose P, Ali AQ, Fang R, Forbes D, Ballard B, Ismail N. The interaction between IL-18 and IL-18 receptor limits the magnitude of protective immunity and enhances pathogenic responses following infection with intracellular bacteria. J Immunol. 2011 Aug 01; 187(3):1333-46.

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Snyder-Cappione JE, Tincati C, Eccles-James IG, Cappione AJ, Ndhlovu LC, Koth LL, Nixon DF. A comprehensive ex vivo functional analysis of human NKT cells reveals production of MIP1-a and MIP1-?, a lack of IL-17, and a Th1-bias in males. PLoS One. 2010 Nov 03; 5(11):e15412.

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Ndhlovu LC, Snyder-Cappione JE, Carvalho KI, Leal FE, Loo CP, Bruno FR, Jha AR, Devita D, Hasenkrug AM, Barbosa HM, Segurado AC, Nixon DF, Murphy EL, Kallas EG. Lower numbers of circulating Natural Killer T (NK T) cells in individuals with human T lymphotropic virus type 1 (HTLV-1) associated neurological disease. Clin Exp Immunol. 2009 Dec; 158(3):294-9.

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