Galectins

"Galectins" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure, which enables searching at various levels of specificity.

MeSH information

Definition | Details | More General Concepts | Related Concepts | More Specific Concepts

A class of animal lectins that bind specifically to beta-galactoside in a calcium-independent manner. Members of this class are distiguished from other lectins by the presence of a conserved carbohydrate recognition domain. The majority of proteins in this class bind to sugar molecules in a sulfhydryl-dependent manner and are often referred to as S-type lectins, however this property is not required for membership in this class.

Descriptor ID	D037161
MeSH Number(s)	D12.776.503.307
Concept/Terms	Galectins Galectins beta-Galactoside Binding Lectin Binding Lectin, beta-Galactoside Lectin, beta-Galactoside Binding beta Galactoside Binding Lectin D-Galactoside-Binding Lectin D Galactoside Binding Lectin Lectin, D-Galactoside-Binding S-Type Lectins S Type Lectins Galaptins Galectin Lectins, S-Type Lectins, S Type S-Type Lectin Lectin, S-Type S Type Lectin beta-D-Galactosyl-Specific Lectin Lectin, beta-D-Galactosyl-Specific beta D Galactosyl Specific Lectin Galactose-Binding Lectin Galactose Binding Lectin Lectin, Galactose-Binding beta-D-Gal(1-3)D-GalNAc Specific Lectins beta-D-Gal(1-3)D-GalNAc Specific Lectins

Below are MeSH descriptors whose meaning is more general than "Galectins".

Chemicals and Drugs [D]
Amino Acids, Peptides, and Proteins [D12]
Proteins [D12.776]
Lectins [D12.776.503]
Galectins [D12.776.503.307]

Below are MeSH descriptors whose meaning is related to "Galectins".

Below are MeSH descriptors whose meaning is more specific than "Galectins".

publications

Timeline | Most Recent

This graph shows the total number of publications written about "Galectins" by people in this website by year, and whether "Galectins" was a major or minor topic of these publications.

Bar chart showing 18 publications over 11 distinct years, with a maximum of 3 publications in 2018

To see the data from this visualization as text, click here.

Year	Major Topic	Minor Topic	Total
2011	0	1	1
2013	1	1	2
2014	1	0	1
2016	1	1	2
2018	1	2	3
2019	1	0	1
2020	0	1	1
2021	1	1	2
2022	0	2	2
2023	2	0	2
2024	1	0	1

Below are the most recent publications written about "Galectins" by people in Profiles.

Moar P, Linn K, Premeaux TA, Bowler S, Sardarni UK, Gopalan BP, Shwe EE, San T, Han H, Clements D, Hlaing CS, Kyu EH, Thair C, Mar YY, Nway N, Mannarino J, Bolzenius J, Mar S, Aye AMM, Tandon R, Paul R, Ndhlovu LC. Plasma galectin-9 relates to cognitive performance and inflammation among adolescents with vertically acquired HIV. AIDS. 2024 Aug 01; 38(10):1460-1467.

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Du L, Bouzidi MS, Gala A, Deiter F, Billaud JN, Yeung ST, Dabral P, Jin J, Simmons G, Dossani ZY, Niki T, Ndhlovu LC, Greenland JR, Pillai SK. Human galectin-9 potently enhances SARS-CoV-2 replication and inflammation in airway epithelial cells. J Mol Cell Biol. 2023 08 03; 15(4).

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Premeaux TA, Yeung ST, Pillai SK, Ndhlovu LC. Elevated Galectin-9 across the human brain correlates with HIV neuropathology and detrimental cognitive states. J Neurovirol. 2023 06; 29(3):337-345.

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Yuan Z, Giron LB, Hart C, Gyampoh A, Koshy J, Hong KY, Niki T, Premeaux TA, Ndhlovu LC, Deleage C, Montaner LJ, Abdel-Mohsen M. Human galectin-9 promotes the expansion of HIV reservoirs in vivo in humanized mice. AIDS. 2023 03 15; 37(4):571-577.

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Yeung ST, Premeaux TA, Du L, Niki T, Pillai SK, Khanna KM, Ndhlovu LC. Galectin-9 protects humanized-ACE2 immunocompetent mice from SARS-CoV-2 infection. Front Immunol. 2022; 13:1011185.

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Chou WC, Tsai KL, Hsieh PL, Wu CH, Jou IM, Tu YK, Ma CH. Galectin-3 facilitates inflammation and apoptosis in chondrocytes through upregulation of the TLR-4-mediated oxidative stress pathway in TC28a2 human chondrocyte cells. Environ Toxicol. 2022 Mar; 37(3):478-488.

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Premeaux TA, Moser CB, McKhann A, Hoenigl M, Laws EI, Aquino DL, Lederman MM, Landay AL, Gianella S, Ndhlovu LC. Plasma galectin-9 as a predictor of adverse non-AIDS events in persons with chronic HIV during suppressive antiretroviral therapy. AIDS. 2021 12 01; 35(15):2489-2495.

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Premeaux TA, Javandel S, Hosaka KRJ, Greene M, Therrien N, Allen IE, Corley MJ, Valcour VG, Ndhlovu LC. Associations Between Plasma Immunomodulatory and Inflammatory Mediators With VACS Index Scores Among Older HIV-Infected Adults on Antiretroviral Therapy. Front Immunol. 2020; 11:1321.

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Colomb F, Giron LB, Premeaux TA, Mitchell BI, Niki T, Papasavvas E, Montaner LJ, Ndhlovu LC, Abdel-Mohsen M. Galectin-9 Mediates HIV Transcription by Inducing TCR-Dependent ERK Signaling. Front Immunol. 2019; 10:267.

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Premeaux TA, D'Antoni ML, Abdel-Mohsen M, Pillai SK, Kallianpur KJ, Nakamoto BK, Agsalda-Garcia M, Shiramizu B, Shikuma CM, Gissl?n M, Price RW, Valcour V, Ndhlovu LC. Elevated cerebrospinal fluid Galectin-9 is associated with central nervous system immune activation and poor cognitive performance in older HIV-infected individuals. J Neurovirol. 2019 04; 25(2):150-161.

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