CD8-Positive T-Lymphocytes

"CD8-Positive T-Lymphocytes" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure, which enables searching at various levels of specificity.

MeSH information

Definition | Details | More General Concepts | Related Concepts | More Specific Concepts

A critical subpopulation of regulatory T-lymphocytes involved in MHC Class I-restricted interactions. They include both cytotoxic T-lymphocytes (T-LYMPHOCYTES, CYTOTOXIC) and CD8+ suppressor T-lymphocytes.

Descriptor ID	D018414
MeSH Number(s)	A11.118.637.555.567.569.220 A15.145.229.637.555.567.569.220 A15.382.490.555.567.569.220
Concept/Terms	CD8-Positive T-Lymphocytes CD8-Positive T-Lymphocytes CD8 Positive T Lymphocytes CD8-Positive T-Lymphocyte T-Lymphocyte, CD8-Positive T-Lymphocytes, CD8-Positive T8 Lymphocytes Lymphocyte, T8 Lymphocytes, T8 T8 Lymphocyte T8 Cells Cell, T8 Cells, T8 T8 Cell CD8-Positive Lymphocytes CD8 Positive Lymphocytes CD8-Positive Lymphocyte Lymphocyte, CD8-Positive Lymphocytes, CD8-Positive Suppressor T-Lymphocytes, CD8-Positive Suppressor T-Lymphocytes, CD8-Positive CD8-Positive Suppressor T-Lymphocyte CD8-Positive Suppressor T-Lymphocytes Suppressor T Lymphocytes, CD8 Positive Suppressor T-Lymphocyte, CD8-Positive T-Lymphocyte, CD8-Positive Suppressor T-Lymphocytes, CD8-Positive Suppressor Suppressor T-Cells, CD8-Positive CD8-Positive Suppressor T-Cell CD8-Positive Suppressor T-Cells Suppressor T Cells, CD8 Positive Suppressor T-Cell, CD8-Positive T-Cell, CD8-Positive Suppressor T-Cells, CD8-Positive Suppressor

Below are MeSH descriptors whose meaning is more general than "CD8-Positive T-Lymphocytes".

Anatomy [A]
Cells [A11]
Blood Cells [A11.118]
Leukocytes [A11.118.637]
Leukocytes, Mononuclear [A11.118.637.555]
Lymphocytes [A11.118.637.555.567]
T-Lymphocytes [A11.118.637.555.567.569]
CD8-Positive T-Lymphocytes [A11.118.637.555.567.569.220]
Hemic and Immune Systems [A15]
Blood [A15.145]
Blood Cells [A15.145.229]
Leukocytes [A15.145.229.637]
Leukocytes, Mononuclear [A15.145.229.637.555]
Lymphocytes [A15.145.229.637.555.567]
T-Lymphocytes [A15.145.229.637.555.567.569]
CD8-Positive T-Lymphocytes [A15.145.229.637.555.567.569.220]
Immune System [A15.382]
Leukocytes [A15.382.490]
Leukocytes, Mononuclear [A15.382.490.555]
Lymphocytes [A15.382.490.555.567]
T-Lymphocytes [A15.382.490.555.567.569]
CD8-Positive T-Lymphocytes [A15.382.490.555.567.569.220]

Below are MeSH descriptors whose meaning is related to "CD8-Positive T-Lymphocytes".

Below are MeSH descriptors whose meaning is more specific than "CD8-Positive T-Lymphocytes".

CD8-Positive T-Lymphocytes
T-Lymphocytes, Cytotoxic

publications

Timeline | Most Recent

This graph shows the total number of publications written about "CD8-Positive T-Lymphocytes" by people in this website by year, and whether "CD8-Positive T-Lymphocytes" was a major or minor topic of these publications.

Bar chart showing 115 publications over 28 distinct years, with a maximum of 10 publications in 2015

To see the data from this visualization as text, click here.

Year	Major Topic	Minor Topic	Total
1996	1	1	2
1997	0	1	1
1998	2	1	3
1999	1	0	1
2001	1	1	2
2002	1	3	4
2003	0	1	1
2004	1	1	2
2005	0	1	1
2006	0	3	3
2007	3	4	7
2008	1	3	4
2009	3	3	6
2010	3	3	6
2011	4	1	5
2012	2	4	6
2013	3	5	8
2014	3	0	3
2015	6	4	10
2016	3	5	8
2017	3	3	6
2018	1	0	1
2019	2	2	4
2020	4	1	5
2021	2	4	6
2022	2	4	6
2023	0	2	2
2024	1	1	2

Below are the most recent publications written about "CD8-Positive T-Lymphocytes" by people in Profiles.

Webb GM, Pessoa CT, McCullen AJ, Hwang JM, Humkey MC, Thormin-Odum R, Kukula KA, Smedley J, Fischer M, Sciurba J, Bochart RM, Shriver-Munsch C, Ndhlovu LC, Sacha JB. Immune restoration by TIGIT blockade is insufficient to control chronic SIV infection. J Virol. 2024 Jun 13; 98(6):e0027324.

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Kidman J, Zemek RM, Sidhom JW, Correa D, Principe N, Sheikh F, Fear VS, Forbes CA, Chopra A, Boon L, Zaitouny A, de Jong E, Holt RA, Jones M, Millward MJ, Lassmann T, Forrest ARR, Nowak AK, Watson M, Lake RA, Lesterhuis WJ, Chee J. Immune checkpoint therapy responders display early clonal expansion of tumor infiltrating lymphocytes. Oncoimmunology. 2024; 13(1):2345859.

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Rosado MRS, Marzan-Rivera N, Watowich MM, Valle ADN, Pantoja P, Pavez-Fox MA, Siracusa ER, Cooper EB, Valle JEN, Phillips D, Ruiz-Lambides A, Martinez MI, Montague MJ, Platt ML, Higham JP, Brent LJN, Sariol CA, Snyder-Mackler N. Immune cell composition varies by age, sex and exposure to social adversity in free-ranging Rhesus Macaques. Geroscience. 2024 04; 46(2):2107-2122.

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Corley MJ, Pang APS, Shikuma CM, Ndhlovu LC. Cell-type specific impact of metformin on monocyte epigenetic age reversal in virally suppressed older people living with HIV. Aging Cell. 2024 01; 23(1):e13926.

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Postoak JL, Song W, Yang G, Guo X, Xiao S, Saffold CE, Zhang J, Joyce S, Manley NR, Wu L, Van Kaer L. Thymic epithelial cells require lipid kinase Vps34 for CD4 but not CD8 T cell selection. J Exp Med. 2022 10 03; 219(10).

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Gibbs C, So JY, Ahad A, Michalowski AM, Son DS, Li Y. CXCL14 Attenuates Triple-Negative Breast Cancer Progression by Regulating Immune Profiles of the Tumor Microenvironment in a T Cell-Dependent Manner. Int J Mol Sci. 2022 Aug 18; 23(16).

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Paul R, Cho K, Bolzenius J, Sacdalan C, Ndhlovu LC, Trautmann L, Krebs S, Tipsuk S, Crowell TA, Suttichom D, Colby DJ, Premeaux TA, Phanuphak N, Chan P, Kroon E, Vasan S, Hsu D, Carrico A, Valcour V, Ananworanich J, Robb ML, Ake JA, Sriplienchan S, Spudich S. Individual Differences in CD4/CD8 T-Cell Ratio Trajectories and Associated Risk Profiles Modeled From Acute HIV Infection. Psychosom Med. 2022 10 01; 84(8):976-983.

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Nguyen TT, Shin DH, Sohoni S, Singh SK, Rivera-Molina Y, Jiang H, Fan X, Gumin J, Lang FF, Alvarez-Breckenridge C, Godoy-Vitorino F, Zhu L, Zheng WJ, Zhai L, Ladomersky E, Lauing KL, Alonso MM, Wainwright DA, Gomez-Manzano C, Fueyo J. Reshaping the tumor microenvironment with oncolytic viruses, positive regulation of the immune synapse, and blockade of the immunosuppressive oncometabolic circuitry. J Immunother Cancer. 2022 07; 10(7).

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Castilho JL, Bian A, Jenkins CA, Shepherd BE, Sigel K, Gill MJ, Kitahata MM, Silverberg MJ, Mayor AM, Coburn SB, Wiley D, Achenbach CJ, Marconi VC, Bosch RJ, Horberg MA, Rabkin CS, Napravnik S, Novak RM, Mathews WC, Thorne JE, Sun J, Althoff KN, Moore RD, Sterling TR, Sudenga SL. CD4/CD8 Ratio and Cancer Risk Among Adults With HIV. J Natl Cancer Inst. 2022 06 13; 114(6):854-862.

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Heinze K, Nazeran TM, Lee S, Kr?mer P, Cairns ES, Chiu DS, Leung SC, Kang EY, Meagher NS, Kennedy CJ, Boros J, Kommoss F, Vollert HW, Heitz F, du Bois A, Harter P, Grube M, Kraemer B, Staebler A, Kommoss FK, Heublein S, Sinn HP, Singh N, Laslavic A, Elishaev E, Olawaiye A, Moysich K, Modugno F, Sharma R, Brand AH, Harnett PR, DeFazio A, Fortner RT, Lubinski J, Lener M, Toloczko-Grabarek A, Cybulski C, Gronwald H, Gronwald J, Coulson P, El-Bahrawy MA, Jones ME, Schoemaker MJ, Swerdlow AJ, Gorringe KL, Campbell I, Cook L, Gayther SA, Carney ME, Shvetsov YB, Hernandez BY, Wilkens LR, Goodman MT, Mateoiu C, Linder A, Sundfeldt K, Kelemen LE, Gentry-Maharaj A, Widschwendter M, Menon U, Bolton KL, Alsop J, Shah M, Jimenez-Linan M, Pharoah PD, Brenton JD, Cushing-Haugen KL, Harris HR, Doherty JA, Gilks B, Ghatage P, Huntsman DG, Nelson GS, Tinker AV, Lee CH, Goode EL, Nelson BH, Ramus SJ, Kommoss S, Talhouk A, K?bel M, Anglesio MS. Validated biomarker assays confirm that ARID1A loss is confounded with MMR deficiency, CD8+ TIL infiltration, and provides no independent prognostic value in endometriosis-associated ovarian carcinomas. J Pathol. 2022 04; 256(4):388-401.

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