Mutation

"Mutation" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure, which enables searching at various levels of specificity.

MeSH information

Definition | Details | More General Concepts | Related Concepts | More Specific Concepts

Any detectable and heritable change in the genetic material that causes a change in the GENOTYPE and which is transmitted to daughter cells and to succeeding generations.

Descriptor ID	D009154
MeSH Number(s)	G05.365.590
Concept/Terms	Mutation Mutation Mutations

Below are MeSH descriptors whose meaning is more general than "Mutation".

Biological Sciences [G]
Genetic Phenomena [G05]
Genetic Variation [G05.365]
Mutation [G05.365.590]

Below are MeSH descriptors whose meaning is related to "Mutation".

publications

Timeline | Most Recent

This graph shows the total number of publications written about "Mutation" by people in this website by year, and whether "Mutation" was a major or minor topic of these publications.

Bar chart showing 895 publications over 30 distinct years, with a maximum of 52 publications in 2007

To see the data from this visualization as text, click here.

Year	Major Topic	Minor Topic	Total
1995	0	4	4
1996	1	5	6
1997	0	7	7
1998	2	14	16
1999	1	10	11
2000	1	12	13
2001	2	14	16
2002	9	25	34
2003	10	29	39
2004	5	37	42
2005	6	32	38
2006	5	36	41
2007	8	44	52
2008	5	35	40
2009	9	24	33
2010	14	28	42
2011	7	37	44
2012	7	33	40
2013	18	29	47
2014	14	30	44
2015	18	33	51
2016	8	23	31
2017	11	32	43
2018	4	20	24
2019	5	19	24
2020	5	30	35
2021	8	21	29
2022	0	16	16
2023	1	17	18
2024	3	12	15

Below are the most recent publications written about "Mutation" by people in Profiles.

Gregory MD, Ofosu-Asante K, Lazarte JMS, Puente PE, Tawfeeq N, Belony N, Huang Y, Offringa IA, Lamango NS. Treatment of a mutant KRAS lung cancer cell line with polyisoprenylated cysteinyl amide inhibitors activates the MAPK pathway, inhibits cell migration and induces apoptosis. PLoS One. 2024; 19(10):e0312563.

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Hedde PN, Zhu S, Barylko B, Chiu CL, Nelson LT, Digman MA, Albanesi JP, James NG, Jameson DM. Effect of Pathogenic Mutations on the Formation of High-Order Dynamin 2 Assemblies in Living Cells. Biochemistry. 2024 Nov 05; 63(21):2750-2758.

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Chung CS, Kou Y, Shemtov SJ, Verheijen BM, Flores I, Love K, Del Dosso A, Thorwald MA, Liu Y, Hicks D, Sun Y, Toney RG, Carrillo L, Nguyen MM, Biao H, Jin Y, Jauregui AM, Quiroz JD, Head E, Moore DL, Simpson S, Thomas KW, Coba MP, Li Z, Benayoun BA, Rosenthal JJC, Kennedy SR, Quadrato G, Gout JF, Chen L, Vermulst M. Transcript errors generate amyloid-like proteins in huwman cells. Nat Commun. 2024 Oct 07; 15(1):8676.

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Lehle JD, Lin YH, Gomez A, Chavez L, McCarrey JR. An in vitro approach reveals molecular mechanisms underlying endocrine disruptor-induced epimutagenesis. Elife. 2024 Oct 03; 13.

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Peng X, Guo S, Zheng S, Hossain A, Zhang C, Mottamal M, Skripnikova E, Ma P, Martinez-Carter K, Zhang Q, Abedin F, Huckaba T, Wang G. Discovery of Oral Degraders of the ROS1 Fusion Protein with Potent Activity against Secondary Resistance Mutations. J Med Chem. 2024 Oct 24; 67(20):18098-18123.

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Gojanovich GS, Marsit CJ, Kacanek D, Russell J, Hudson G, Van Dyke RB, Naini AB, Gerschenson M. Relationships of mitochondrial DNA mutations and select clinical diagnoses in perinatally HIV- and ART-exposed uninfected children. Mitochondrion. 2024 Nov; 79:101949.

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Jalal MS, Duttaroy A. Maternal Spargel/dPGC-1 is critical for embryonic development and influences chorion gene amplification via Cyclin E activity. Dev Biol. 2024 Dec; 516:158-166.

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Hew BE, Gupta S, Sato R, Waller DF, Stoytchev I, Short JE, Sharek L, Tran CT, Badran AH, Owens JB. Directed evolution of hyperactive integrases for site specific insertion of transgenes. Nucleic Acids Res. 2024 Aug 12; 52(14):e64.

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Williams J, Regedanz E, Lucinda N, Nava Fereira AR, Lacatus G, Berger M, O'Connell N, Coursey T, Ruan J, Bisaro DM, Sunter G. Mutation of the conserved late element in geminivirus CP promoters abolishes Arabidopsis TCP24 transcription factor binding and decreases H3K27me3 levels on viral chromatin. PLoS Pathog. 2024 Jul; 20(7):e1012399.

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Vargas-Maya NI, Maunakea AK, Ram?rez-Montiel FB, Sultana R, Peres R, Mac?as-Cervantes QX, Medina-Nieto AL, Rangel-Serrano ?, Mart?nez-?lvarez JA, P?ramo-P?rez I, Anaya-Vel?zquez F, Padilla-Vaca F, Franco B. Avirulent UG10 Entamoeba histolytica mutant derived from HM-1:IMSS strain shows limited genome variability and aberrant 5-methyl cytosine genomic distribution. Mol Biochem Parasitol. 2024 12; 260:111647.

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