"Codon, Nonsense" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
An amino acid-specifying codon that has been converted to a stop codon (CODON, TERMINATOR) by mutation. Its occurance is abnormal causing premature termination of protein translation and results in production of truncated and non-functional proteins. A nonsense mutation is one that converts an amino acid-specific codon to a stop codon.
Descriptor ID |
D018389
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MeSH Number(s) |
D13.444.735.544.355.250.235 G05.360.335.355.250.235 G05.365.590.195
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Concept/Terms |
Codon, Nonsense- Codon, Nonsense
- Premature Termination Codon
- Codon, Premature Termination
- Codons, Premature Termination
- Premature Termination Codons
- Termination Codon, Premature
- Termination Codons, Premature
- Premature Stop Codon
- Codon, Premature Stop
- Codons, Premature Stop
- Premature Stop Codons
- Stop Codon, Premature
- Stop Codons, Premature
- Nonsense Codon
- Codons, Nonsense
- Nonsense Codons
- Codon, Termination, Premature
Mutation, Nonsense- Mutation, Nonsense
- Mutations, Nonsense
- Nonsense Mutations
- Nonsense Mutation
Ochre Nonsense Codon- Ochre Nonsense Codon
- Codon, Ochre Nonsense
- Codons, Ochre Nonsense
- Nonsense Codon, Ochre
- Nonsense Codons, Ochre
- Ochre Nonsense Codons
Ochre Nonsense Mutation- Ochre Nonsense Mutation
- Mutation, Ochre Nonsense
- Mutations, Ochre Nonsense
- Nonsense Mutation, Ochre
- Nonsense Mutations, Ochre
- Ochre Nonsense Mutations
Amber Nonsense Mutation- Amber Nonsense Mutation
- Amber Nonsense Mutations
- Mutation, Amber Nonsense
- Mutations, Amber Nonsense
- Nonsense Mutation, Amber
- Nonsense Mutations, Amber
Opal Nonsense Mutation- Opal Nonsense Mutation
- Mutation, Opal Nonsense
- Mutations, Opal Nonsense
- Nonsense Mutation, Opal
- Nonsense Mutations, Opal
- Opal Nonsense Mutations
Amber Nonsense Codon- Amber Nonsense Codon
- Amber Nonsense Codons
- Codon, Amber Nonsense
- Codons, Amber Nonsense
- Nonsense Codons, Amber
- Nonsense Codon, Amber
Codon, Unassigned- Codon, Unassigned
- Codons, Unassigned
- Unassigned Codons
- Unassigned Codon
Opal Nonsense Codon- Opal Nonsense Codon
- Codon, Opal Nonsense
- Codons, Opal Nonsense
- Nonsense Codon, Opal
- Nonsense Codons, Opal
- Opal Nonsense Codons
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Below are MeSH descriptors whose meaning is more general than "Codon, Nonsense".
Below are MeSH descriptors whose meaning is more specific than "Codon, Nonsense".
This graph shows the total number of publications written about "Codon, Nonsense" by people in this website by year, and whether "Codon, Nonsense" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
Year | Major Topic | Minor Topic | Total |
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2008 | 0 | 1 | 1 |
2009 | 1 | 0 | 1 |
2010 | 1 | 0 | 1 |
2011 | 0 | 1 | 1 |
2012 | 0 | 1 | 1 |
2013 | 0 | 2 | 2 |
2016 | 0 | 2 | 2 |
2017 | 0 | 1 | 1 |
2021 | 0 | 1 | 1 |
2023 | 0 | 2 | 2 |
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click here.
Below are the most recent publications written about "Codon, Nonsense" by people in Profiles.
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Diaz Quiroz JF, Ojha N, Shayhidin EE, De Silva D, Dabney J, Lancaster A, Coull J, Milstein S, Fraley AW, Brown CR, Rosenthal JJC. Development of a selection assay for small guide RNAs that drive efficient site-directed RNA editing. Nucleic Acids Res. 2023 04 24; 51(7):e41.
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Castro VL, Paz D, Virrueta V, Estevao IL, Grajeda BI, Ellis CC, Quintana AM. Missense and nonsense mutations of the zebrafish hcfc1a gene result in contrasting mTor and radial glial phenotypes. Gene. 2023 May 15; 864:147290.
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Salanga CM, Salanga MC. Genotype to Phenotype: CRISPR Gene Editing Reveals Genetic Compensation as a Mechanism for Phenotypic Disjunction of Morphants and Mutants. Int J Mol Sci. 2021 Mar 27; 22(7).
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Vallecillo-Viejo IC, Liscovitch-Brauer N, Montiel-Gonzalez MF, Eisenberg E, Rosenthal JJC. Abundant off-target edits from site-directed RNA editing can be reduced by nuclear localization of the editing enzyme. RNA Biol. 2018 01 02; 15(1):104-114.
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Montiel-Gonz?lez MF, Vallecillo-Viejo IC, Rosenthal JJ. An efficient system for selectively altering genetic information within mRNAs. Nucleic Acids Res. 2016 12 01; 44(21):e157.
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Fong KS, Hufnagel RB, Khadka VS, Corley MJ, Maunakea AK, Fogelgren B, Ahmed ZM, Lozanoff S. A mutation in the tuft mouse disrupts TET1 activity and alters the expression of genes that are crucial for neural tube closure. Dis Model Mech. 2016 05 01; 9(5):585-96.
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Montiel-Gonzalez MF, Vallecillo-Viejo I, Yudowski GA, Rosenthal JJ. Correction of mutations within the cystic fibrosis transmembrane conductance regulator by site-directed RNA editing. Proc Natl Acad Sci U S A. 2013 Nov 05; 110(45):18285-90.
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Price EP, Sarovich DS, Mayo M, Tuanyok A, Drees KP, Kaestli M, Beckstrom-Sternberg SM, Babic-Sternberg JS, Kidd TJ, Bell SC, Keim P, Pearson T, Currie BJ. Within-host evolution of Burkholderia pseudomallei over a twelve-year chronic carriage infection. mBio. 2013 Jul 16; 4(4).
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Conley ME, Dobbs AK, Quintana AM, Bosompem A, Wang YD, Coustan-Smith E, Smith AM, Perez EE, Murray PJ. Agammaglobulinemia and absent B lineage cells in a patient lacking the p85a subunit of PI3K. J Exp Med. 2012 Mar 12; 209(3):463-70.
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Franco HL, Casasnovas JJ, Leon RG, Friesel R, Ge Y, Desnick RJ, Cadilla CL. Nonsense mutations of the bHLH transcription factor TWIST2 found in Setleis Syndrome patients cause dysregulation of periostin. Int J Biochem Cell Biol. 2011 Oct; 43(10):1523-31.