Point Mutation

"Point Mutation" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure, which enables searching at various levels of specificity.

MeSH information

Definition | Details | More General Concepts | Related Concepts | More Specific Concepts

A mutation caused by the substitution of one nucleotide for another. This results in the DNA molecule having a change in a single base pair.

Descriptor ID	D017354
MeSH Number(s)	G05.365.590.675
Concept/Terms	Point Mutation Point Mutation Mutation, Point Mutations, Point Point Mutations

Below are MeSH descriptors whose meaning is more general than "Point Mutation".

Biological Sciences [G]
Genetic Phenomena [G05]
Genetic Variation [G05.365]
Mutation [G05.365.590]
Point Mutation [G05.365.590.675]

Below are MeSH descriptors whose meaning is more specific than "Point Mutation".

publications

Timeline | Most Recent

This graph shows the total number of publications written about "Point Mutation" by people in this website by year, and whether "Point Mutation" was a major or minor topic of these publications.

Bar chart showing 77 publications over 26 distinct years, with a maximum of 7 publications in 2003 and 2005

To see the data from this visualization as text, click here.

Year	Major Topic	Minor Topic	Total
1994	0	1	1
1995	1	1	2
1996	1	0	1
1998	1	0	1
1999	1	1	2
2000	2	0	2
2001	2	3	5
2002	1	3	4
2003	2	5	7
2004	0	5	5
2005	0	7	7
2006	2	3	5
2007	0	1	1
2008	2	1	3
2009	1	4	5
2010	1	0	1
2011	0	2	2
2012	0	1	1
2014	3	3	6
2015	0	2	2
2016	1	2	3
2017	1	2	3
2018	0	2	2
2019	1	1	2
2020	1	0	1
2021	1	2	3

Below are the most recent publications written about "Point Mutation" by people in Profiles.

Tsai WY, Ching LL, Hsieh SC, Melish ME, Nerurkar VR, Wang WK. A real-time and high-throughput neutralization test based on SARS-CoV-2 pseudovirus containing monomeric infrared fluorescent protein as reporter. Emerg Microbes Infect. 2021 Dec; 10(1):894-904.

View in: PubMed
Almanasra A, Havranek B, Islam SM. In-silico screening and microsecond molecular dynamics simulations to identify single point mutations that destabilize ?-hexosaminidase A causing Tay-Sachs disease. Proteins. 2021 11; 89(11):1587-1601.

View in: PubMed
Borrero-Garc?a LD, Del Mar Maldonado M, Medina-Vel?zquez J, Troche-Torres AL, Velazquez L, Grafals-Ruiz N, Dharmawardhane S. Rac inhibition as a novel therapeutic strategy for EGFR/HER2 targeted therapy resistant breast cancer. BMC Cancer. 2021 Jun 01; 21(1):652.

View in: PubMed
Gordeuk VR, Shah BN, Zhang X, Thuma PE, Zulu S, Moono R, Reading NS, Song J, Zhang Y, Nouraie M, Campbell A, Minniti CP, Rana SR, Darbari DS, Kato GJ, Niu M, Castro OL, Machado R, Gladwin MT, Prchal JT. The CYB5R3c.350C>G and G6PD A alleles modify severity of anemia in malaria and sickle cell disease. Am J Hematol. 2020 11; 95(11):1269-1279.

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Stenzoski NE, Zou J, Piserchio A, Ghose R, Holehouse AS, Raleigh DP. The Cold-Unfolded State Is Expanded but Contains Long- and Medium-Range Contacts and Is Poorly Described by Homopolymer Models. Biochemistry. 2020 09 15; 59(36):3290-3299.

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Dutil J, Teer JK, Golubeva V, Yoder S, Tong WL, Arroyo N, Karam R, Echenique M, Matta JL, Monteiro AN. Germline variants in cancer genes in high-risk non-BRCA patients from Puerto Rico. Sci Rep. 2019 11 28; 9(1):17769.

View in: PubMed
Sarker M, Lee HT, Mei L, Krokhotin A, de Los Reyes SE, Yen L, Costantini LM, Griffith J, Dokholyan NV, Alushin GM, Campbell SL. Cardiomyopathy Mutations in Metavinculin Disrupt Regulation of Vinculin-Induced F-Actin Assemblies. J Mol Biol. 2019 04 05; 431(8):1604-1618.

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Manda B, Mir H, Gangwar R, Meena AS, Amin S, Shukla PK, Dalal K, Suzuki T, Rao R. Phosphorylation hotspot in the C-terminal domain of occludin regulates the dynamics of epithelial junctional complexes. J Cell Sci. 2018 04 06; 131(7).

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Morel C, Sherrin T, Kennedy NJ, Forest KH, Avcioglu Barutcu S, Robles M, Carpenter-Hyland E, Alfulaij N, Standen CL, Nichols RA, Benveniste M, Davis RJ, Todorovic C. JIP1-Mediated JNK Activation Negatively Regulates Synaptic Plasticity and Spatial Memory. J Neurosci. 2018 04 11; 38(15):3708-3728.

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Figliozzi RW, Chen F, Hsia SV. Reversing thyroid-hormone-mediated repression of a HSV-1 promoter via computationally guided mutagenesis. J Cell Sci. 2017 Nov 01; 130(21):3740-3748.

View in: PubMed

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