Astrocytes

"Astrocytes" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure, which enables searching at various levels of specificity.

MeSH information

Definition | Details | More General Concepts | Related Concepts | More Specific Concepts

A class of large neuroglial (macroglial) cells in the central nervous system - the largest and most numerous neuroglial cells in the brain and spinal cord. Astrocytes (from "star" cells) are irregularly shaped with many long processes, including those with "end feet" which form the glial (limiting) membrane and directly and indirectly contribute to the BLOOD-BRAIN BARRIER. They regulate the extracellular ionic and chemical environment, and "reactive astrocytes" (along with MICROGLIA) respond to injury.

Descriptor ID	D001253
MeSH Number(s)	A08.637.200 A11.650.200
Concept/Terms	Astrocytes Astrocytes Astrocyte Astroglia Astroglias

Below are MeSH descriptors whose meaning is more general than "Astrocytes".

Anatomy [A]
Nervous System [A08]
Neuroglia [A08.637]
Astrocytes [A08.637.200]
Cells [A11]
Neuroglia [A11.650]
Astrocytes [A11.650.200]

Below are MeSH descriptors whose meaning is related to "Astrocytes".

Below are MeSH descriptors whose meaning is more specific than "Astrocytes".

publications

Timeline | Most Recent

This graph shows the total number of publications written about "Astrocytes" by people in this website by year, and whether "Astrocytes" was a major or minor topic of these publications.

Bar chart showing 160 publications over 30 distinct years, with a maximum of 15 publications in 2010

To see the data from this visualization as text, click here.

Year	Major Topic	Minor Topic	Total
1995	4	0	4
1996	1	1	2
1997	2	0	2
1998	3	1	4
1999	1	2	3
2000	0	1	1
2001	1	0	1
2002	3	2	5
2003	2	0	2
2004	2	2	4
2005	0	4	4
2006	3	4	7
2007	3	2	5
2008	0	4	4
2009	2	1	3
2010	10	5	15
2011	4	2	6
2012	6	3	9
2013	7	1	8
2014	8	2	10
2015	6	1	7
2016	5	3	8
2017	4	2	6
2018	2	3	5
2019	7	4	11
2020	4	1	5
2021	3	2	5
2022	3	4	7
2023	3	1	4
2024	1	2	3

Below are the most recent publications written about "Astrocytes" by people in Profiles.

Duarte Y, Quintana-Donoso D, Moraga-Amaro R, Dinamarca I, Lemunao Y, C?rdenas K, Bahamonde T, Barrientos T, Olivares P, Navas C, Carvajal FJ, Santib?nez Y, Castro-Lazo R, Paz Meza M, Jorquera R, G?mez GI, Henke M, Alarc?n R, Gabriel LA, Schiffmann S, Cerpa W, Retamal MA, Simon F, Linsambarth S, Gonzalez-Nilo F, Stehberg J. The role of astrocytes in depression, its prevention, and treatment by targeting astroglial gliotransmitter release. Proc Natl Acad Sci U S A. 2024 Nov 12; 121(46):e2307953121.

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Goodman LD, Ralhan I, Li X, Lu S, Moulton MJ, Park YJ, Zhao P, Kanca O, Ghaderpour Taleghani ZS, Jacquemyn J, Shulman JM, Ando K, Sun K, Ioannou MS, Bellen HJ. Tau is required for glial lipid droplet formation and resistance to neuronal oxidative stress. Nat Neurosci. 2024 Oct; 27(10):1918-1933.

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Wu L, Liu Y, He Q, Ao G, Xu N, He W, Liu X, Huang L, Yu Q, Kanamaru H, Dong S, Zhu S, Yuan Y, Han M, Ling Y, Liu L, Wu C, Zhou Y, Sherchan P, Flores JJ, Tang J, Chen X, He X, Zhang JH. PEDF-34 attenuates neurological deficit and suppresses astrocyte-dependent neuroinflammation by modulating astrocyte polarization via 67LR/JNK/STAT1 signaling pathway after subarachnoid hemorrhage in rats. J Neuroinflammation. 2024 Jul 21; 21(1):178.

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Farris T, Gonz?lez-Ochoa S, Mohammed M, Rajakaruna H, Tonello J, Kanagasabai T, Korolkova O, Shimamoto A, Ivanova A, Shanker A. Loss of Mitochondrial Tusc2/Fus1 Triggers a Brain Pro-Inflammatory Microenvironment and Early Spatial Memory Impairment. Int J Mol Sci. 2024 Jul 05; 25(13).

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Rorex C, Cardona SM, Church KA, Rodriguez D, Vanegas D, Saldivar R, Faz B, Cardona AE. Astrogliosis in the GFAP-CreERT2:Rosa26iDTR Mouse Model Does Not Exacerbate Retinal Microglia Activation or M?ller Cell Gliosis under Hypoxic Conditions. Biomolecules. 2024 May 10; 14(5).

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Correia SC, Perry G, Moreira PI. Fueling Alzheimer's Disease: Where Does Immunometabolism Stand? J Alzheimers Dis. 2024; 100(s1):S363-S385.

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Capuz A, Osien S, Cardon T, Karnoub MA, Aboulouard S, Raffo-Romero A, Duhamel M, Cizkova D, Trerotola M, Devos D, Kobeissy F, Vanden Abeele F, Bonnefond A, Fournier I, Rodet F, Salzet M. Heimdall, an alternative protein issued from a ncRNA related to kappa light chain variable region of immunoglobulins from astrocytes: a new player in neural proteome. Cell Death Dis. 2023 08 16; 14(8):526.

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Cottam NC, Bamfo T, Harrington MA, Charvet CJ, Hekmatyar K, Tulin N, Sun J. Cerebellar structural, astrocytic, and neuronal abnormalities in the SMN?7 mouse model of spinal muscular atrophy. Brain Pathol. 2023 09; 33(5):e13162.

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Capuz A, Osien S, Karnoub MA, Aboulouard S, Laurent E, Coyaud E, Raffo-Romero A, Duhamel M, Bonnefond A, Derhourhi M, Trerotola M, El Yazidi-Belkoura I, Devos D, Zilkova M, Kobeissy F, Vanden Abeele F, Fournier I, Cizkova D, Rodet F, Salzet M. Astrocytes express aberrant immunoglobulins as putative gatekeeper of astrocytes to neuronal progenitor conversion. Cell Death Dis. 2023 04 04; 14(4):237.

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Kim S, Pajarillo E, Nyarko-Danquah I, Aschner M, Lee E. Role of Astrocytes in Parkinson's Disease Associated with Genetic Mutations and Neurotoxicants. Cells. 2023 02 15; 12(4).

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