Astrocytes

"Astrocytes" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure, which enables searching at various levels of specificity.

MeSH information

Definition | Details | More General Concepts | Related Concepts | More Specific Concepts

A class of large neuroglial (macroglial) cells in the central nervous system - the largest and most numerous neuroglial cells in the brain and spinal cord. Astrocytes (from "star" cells) are irregularly shaped with many long processes, including those with "end feet" which form the glial (limiting) membrane and directly and indirectly contribute to the BLOOD-BRAIN BARRIER. They regulate the extracellular ionic and chemical environment, and "reactive astrocytes" (along with MICROGLIA) respond to injury.

Descriptor ID	D001253
MeSH Number(s)	A08.637.200 A11.650.200
Concept/Terms	Astrocytes Astrocytes Astrocyte Astroglia Astroglias

Below are MeSH descriptors whose meaning is more general than "Astrocytes".

Anatomy [A]
Nervous System [A08]
Neuroglia [A08.637]
Astrocytes [A08.637.200]
Cells [A11]
Neuroglia [A11.650]
Astrocytes [A11.650.200]

Below are MeSH descriptors whose meaning is related to "Astrocytes".

Below are MeSH descriptors whose meaning is more specific than "Astrocytes".

publications

Timeline | Most Recent

This graph shows the total number of publications written about "Astrocytes" by people in this website by year, and whether "Astrocytes" was a major or minor topic of these publications.

Bar chart showing 162 publications over 31 distinct years, with a maximum of 15 publications in 2010

To see the data from this visualization as text, click here.

Year	Major Topic	Minor Topic	Total
1994	2	0	2
1995	4	0	4
1996	1	1	2
1997	2	0	2
1998	3	1	4
1999	1	2	3
2000	0	1	1
2001	1	0	1
2002	3	2	5
2003	2	0	2
2004	2	2	4
2005	0	4	4
2006	3	4	7
2007	3	2	5
2008	0	4	4
2009	2	1	3
2010	10	5	15
2011	4	2	6
2012	6	3	9
2013	7	1	8
2014	8	2	10
2015	6	1	7
2016	5	3	8
2017	4	2	6
2018	2	3	5
2019	7	4	11
2020	4	1	5
2021	3	2	5
2022	3	4	7
2023	3	1	4
2024	1	2	3

Below are the most recent publications written about "Astrocytes" by people in Profiles.

Wu L, Liu Y, He Q, Ao G, Xu N, He W, Liu X, Huang L, Yu Q, Kanamaru H, Dong S, Zhu S, Yuan Y, Han M, Ling Y, Liu L, Wu C, Zhou Y, Sherchan P, Flores JJ, Tang J, Chen X, He X, Zhang JH. PEDF-34 attenuates neurological deficit and suppresses astrocyte-dependent neuroinflammation by modulating astrocyte polarization via 67LR/JNK/STAT1 signaling pathway after subarachnoid hemorrhage in rats. J Neuroinflammation. 2024 Jul 21; 21(1):178.

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Farris T, Gonz?lez-Ochoa S, Mohammed M, Rajakaruna H, Tonello J, Kanagasabai T, Korolkova O, Shimamoto A, Ivanova A, Shanker A. Loss of Mitochondrial Tusc2/Fus1 Triggers a Brain Pro-Inflammatory Microenvironment and Early Spatial Memory Impairment. Int J Mol Sci. 2024 Jul 05; 25(13).

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Rorex C, Cardona SM, Church KA, Rodriguez D, Vanegas D, Saldivar R, Faz B, Cardona AE. Astrogliosis in the GFAP-CreERT2:Rosa26iDTR Mouse Model Does Not Exacerbate Retinal Microglia Activation or M?ller Cell Gliosis under Hypoxic Conditions. Biomolecules. 2024 May 10; 14(5).

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Capuz A, Osien S, Cardon T, Karnoub MA, Aboulouard S, Raffo-Romero A, Duhamel M, Cizkova D, Trerotola M, Devos D, Kobeissy F, Vanden Abeele F, Bonnefond A, Fournier I, Rodet F, Salzet M. Heimdall, an alternative protein issued from a ncRNA related to kappa light chain variable region of immunoglobulins from astrocytes: a new player in neural proteome. Cell Death Dis. 2023 Aug 16; 14(8):526.

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Cottam NC, Bamfo T, Harrington MA, Charvet CJ, Hekmatyar K, Tulin N, Sun J. Cerebellar structural, astrocytic, and neuronal abnormalities in the SMN?7 mouse model of spinal muscular atrophy. Brain Pathol. 2023 09; 33(5):e13162.

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Capuz A, Osien S, Karnoub MA, Aboulouard S, Laurent E, Coyaud E, Raffo-Romero A, Duhamel M, Bonnefond A, Derhourhi M, Trerotola M, El Yazidi-Belkoura I, Devos D, Zilkova M, Kobeissy F, Vanden Abeele F, Fournier I, Cizkova D, Rodet F, Salzet M. Astrocytes express aberrant immunoglobulins as putative gatekeeper of astrocytes to neuronal progenitor conversion. Cell Death Dis. 2023 Apr 04; 14(4):237.

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Kim S, Pajarillo E, Nyarko-Danquah I, Aschner M, Lee E. Role of Astrocytes in Parkinson's Disease Associated with Genetic Mutations and Neurotoxicants. Cells. 2023 02 15; 12(4).

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Benedikt J, Malpica-Nieves CJ, Rivera Y, M?ndez-Gonz?lez M, Nichols CG, Veh RW, Eaton MJ, Skatchkov SN. The Polyamine Spermine Potentiates the Propagation of Negatively Charged Molecules through the Astrocytic Syncytium. Biomolecules. 2022 12 05; 12(12).

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Kong W, Montano M, Corley MJ, Helmy E, Kobayashi H, Kinisu M, Suryawanshi R, Luo X, Royer LA, Roan NR, Ott M, Ndhlovu LC, Greene WC. Neuropilin-1 Mediates SARS-CoV-2 Infection of Astrocytes in Brain Organoids, Inducing Inflammation Leading to Dysfunction and Death of Neurons. mBio. 2022 12 20; 13(6):e0230822.

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Cancel LM, Silas D, Bikson M, Tarbell JM. Direct current stimulation modulates gene expression in isolated astrocytes with implications for glia-mediated plasticity. Sci Rep. 2022 10 26; 12(1):17964.

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