"Neuroprotective Agents" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Drugs intended to prevent damage to the brain or spinal cord from ischemia, stroke, convulsions, or trauma. Some must be administered before the event, but others may be effective for some time after. They act by a variety of mechanisms, but often directly or indirectly minimize the damage produced by endogenous excitatory amino acids.
| Descriptor ID |
D018696
|
| MeSH Number(s) |
D27.505.696.706.548 D27.505.954.427.575
|
| Concept/Terms |
Neuroprotective Agents- Neuroprotective Agents
- Agents, Neuroprotective
- Neuroprotectants
- Neuroprotective Drugs
- Drugs, Neuroprotective
Neuroprotective Effect- Neuroprotective Effect
- Effect, Neuroprotective
- Neuroprotective Effects
- Effects, Neuroprotective
|
Below are MeSH descriptors whose meaning is more general than "Neuroprotective Agents".
Below are MeSH descriptors whose meaning is more specific than "Neuroprotective Agents".
This graph shows the total number of publications written about "Neuroprotective Agents" by people in this website by year, and whether "Neuroprotective Agents" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 2000 | 1 | 0 | 1 |
| 2001 | 1 | 1 | 2 |
| 2002 | 5 | 1 | 6 |
| 2003 | 6 | 3 | 9 |
| 2004 | 2 | 3 | 5 |
| 2005 | 4 | 4 | 8 |
| 2006 | 5 | 5 | 10 |
| 2007 | 4 | 1 | 5 |
| 2008 | 7 | 2 | 9 |
| 2009 | 5 | 1 | 6 |
| 2010 | 6 | 3 | 9 |
| 2011 | 10 | 1 | 11 |
| 2012 | 5 | 2 | 7 |
| 2013 | 7 | 3 | 10 |
| 2014 | 11 | 2 | 13 |
| 2015 | 9 | 1 | 10 |
| 2016 | 1 | 2 | 3 |
| 2017 | 12 | 4 | 16 |
| 2018 | 6 | 1 | 7 |
| 2019 | 5 | 2 | 7 |
| 2020 | 6 | 1 | 7 |
| 2021 | 6 | 0 | 6 |
| 2022 | 6 | 0 | 6 |
| 2023 | 2 | 0 | 2 |
To return to the timeline,
click here.
Below are the most recent publications written about "Neuroprotective Agents" by people in Profiles.
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Yu J, Li J, Matei N, Wang W, Tang L, Pang J, Li X, Fang L, Tang J, Zhang JH, Yan M. Intranasal administration of recombinant prosaposin attenuates neuronal apoptosis through GPR37/PI3K/Akt/ASK1 pathway in MCAO rats. Exp Neurol. 2024 Mar; 373:114656.
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Mito S, Cheng B, Garcia BA, Yee Ooi X, Gonzalez D, Ruiz TC, Elisarraras FX, Tsin A. SAR study of niclosamide derivatives for neuroprotective function in SH-SY5Y neuroblastoma. Bioorg Med Chem Lett. 2023 11 15; 96:129498.
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Getachew B, Csoka AB, Copeland RL, Manaye KF, Tizabi Y. Dihydromyricetin Protects Against Salsolinol-Induced Toxicity in Dopaminergic Cell Line: Implication for Parkinson's Disease. Neurotox Res. 2023 Apr; 41(2):141-148.
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Ferrer-Acosta Y, Rodriguez-Mass? S, P?rez D, Eterovic VA, Ferchmin PA, Martins AH. Memantine has a nicotinic neuroprotective pathway in acute hippocampal slices after an NMDA insult. Toxicol In Vitro. 2022 Oct; 84:105453.
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Evans JA, Mendonca P, Soliman KFA. Neuroprotective Effects and Therapeutic Potential of the Citrus Flavonoid Hesperetin in Neurodegenerative Diseases. Nutrients. 2022 May 26; 14(11).
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Payne A, Nahashon S, Taka E, Adinew GM, Soliman KFA. Epigallocatechin-3-Gallate (EGCG): New Therapeutic Perspectives for Neuroprotection, Aging, and Neuroinflammation for the Modern Age. Biomolecules. 2022 02 25; 12(3).
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Yu S, Doycheva DM, Gamdzyk M, Gao Y, Guo Y, Travis ZD, Tang J, Chen WX, Zhang JH. BMS-470539 Attenuates Oxidative Stress and Neuronal Apoptosis via MC1R/cAMP/PKA/Nurr1 Signaling Pathway in a Neonatal Hypoxic-Ischemic Rat Model. Oxid Med Cell Longev. 2022; 2022:4054938.
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Chen WN, Shaikh MF, Bhuvanendran S, Date A, Ansari MT, Radhakrishnan AK, Othman I. Poloxamer 188 (P188), A Potential Polymeric Protective Agent for Central Nervous System Disorders: A Systematic Review. Curr Neuropharmacol. 2022; 20(4):799-808.
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Getachew B, Csoka AB, Garden AR, Copeland RL, Tizabi Y. Sodium Butyrate Protects Against Ethanol-Induced Toxicity in SH-SY5Y Cell Line. Neurotox Res. 2021 Dec; 39(6):2186-2193.
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He M, Kittur FS, Hung CY, Zhang J, Jing L, Sane DC, Li PA, Xie J. A Novel Plant-Produced Asialo-rhuEPO Protects Brain from Ischemic Damage Without Erythropoietic Action. Transl Stroke Res. 2022 04; 13(2):338-354.