Interferon-Stimulated Gene Factor 3

"Interferon-Stimulated Gene Factor 3" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure, which enables searching at various levels of specificity.

MeSH information

Definition | Details | More General Concepts | Related Concepts | More Specific Concepts

A multimeric complex that functions as a ligand-dependent transcription factor. ISGF3 is assembled in the CYTOPLASM and translocated to the CELL NUCLEUS in response to INTERFERON signaling. It consists of ISGF3-GAMMA and ISGF3-ALPHA, and it regulates expression of many interferon-responsive GENES.

Descriptor ID	D050832
MeSH Number(s)	D12.644.360.024.303 D12.776.157.057.061 D12.776.260.513 D12.776.476.024.386 D12.776.930.354
Concept/Terms	Interferon-Stimulated Gene Factor 3 Interferon-Stimulated Gene Factor 3 Interferon Stimulated Gene Factor 3 Transcription Factor ISGF3 ISGF3, Transcription Factor ISGF3 Transcription Factor Transcription Factor, ISGF3 IFN-Stimulated Gene Factor 3 Complex IFN Stimulated Gene Factor 3 Complex ISGF3 Factor

Below are MeSH descriptors whose meaning is more general than "Interferon-Stimulated Gene Factor 3".

Chemicals and Drugs [D]
Amino Acids, Peptides, and Proteins [D12]
Peptides [D12.644]
Intracellular Signaling Peptides and Proteins [D12.644.360]
Adaptor Proteins, Signal Transducing [D12.644.360.024]
Interferon-Stimulated Gene Factor 3 [D12.644.360.024.303]
Proteins [D12.776]
Carrier Proteins [D12.776.157]
Adaptor Proteins, Signal Transducing [D12.776.157.057]
Interferon-Stimulated Gene Factor 3 [D12.776.157.057.061]
DNA-Binding Proteins [D12.776.260]
Interferon-Stimulated Gene Factor 3 [D12.776.260.513]
Intracellular Signaling Peptides and Proteins [D12.776.476]
Adaptor Proteins, Signal Transducing [D12.776.476.024]
Interferon-Stimulated Gene Factor 3 [D12.776.476.024.386]
Transcription Factors [D12.776.930]
Interferon-Stimulated Gene Factor 3 [D12.776.930.354]

Below are MeSH descriptors whose meaning is related to "Interferon-Stimulated Gene Factor 3".

Below are MeSH descriptors whose meaning is more specific than "Interferon-Stimulated Gene Factor 3".

Interferon-Stimulated Gene Factor 3
Interferon-Stimulated Gene Factor 3, alpha Subunit
Interferon-Stimulated Gene Factor 3, gamma Subunit

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