Orphan Nuclear Receptors

"Orphan Nuclear Receptors" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure, which enables searching at various levels of specificity.

MeSH information

Definition | Details | More General Concepts | Related Concepts | More Specific Concepts

A broad category of receptor-like proteins that may play a role in transcriptional-regulation in the CELL NUCLEUS. Many of these proteins are similar in structure to known NUCLEAR RECEPTORS but appear to lack a functional ligand-binding domain, while in other cases the specific ligands have yet to be identified.

Descriptor ID	D057093
MeSH Number(s)	D12.776.260.643 D12.776.826.209 D12.776.930.645
Concept/Terms	Orphan Nuclear Receptors Orphan Nuclear Receptors Nuclear Receptors, Orphan Receptors, Orphan Nuclear

Below are MeSH descriptors whose meaning is more general than "Orphan Nuclear Receptors".

Chemicals and Drugs [D]
Amino Acids, Peptides, and Proteins [D12]
Proteins [D12.776]
DNA-Binding Proteins [D12.776.260]
Orphan Nuclear Receptors [D12.776.260.643]
Receptors, Cytoplasmic and Nuclear [D12.776.826]
Orphan Nuclear Receptors [D12.776.826.209]
Transcription Factors [D12.776.930]
Orphan Nuclear Receptors [D12.776.930.645]

Below are MeSH descriptors whose meaning is related to "Orphan Nuclear Receptors".

Below are MeSH descriptors whose meaning is more specific than "Orphan Nuclear Receptors".

publications

Timeline | Most Recent

This graph shows the total number of publications written about "Orphan Nuclear Receptors" by people in this website by year, and whether "Orphan Nuclear Receptors" was a major or minor topic of these publications.

Bar chart showing 5 publications over 5 distinct years, with a maximum of 1 publications in 2006 and 2011 and 2014 and 2018 and 2019

To see the data from this visualization as text, click here.

Year	Major Topic	Minor Topic	Total
2006	0	1	1
2011	1	0	1
2014	1	0	1
2018	0	1	1
2019	1	0	1

Below are the most recent publications written about "Orphan Nuclear Receptors" by people in Profiles.

Mazaira GI, Zgajnar NR, Lotufo CM, Daneri-Becerra C, Sivils JC, Soto OB, Cox MB, Galigniana MD. Nuclear Receptors: A Historical Perspective. Methods Mol Biol. 2019; 1966:1-5.

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Jean-Charles N, Buenaventura DF, Emerson MM. Identification and characterization of early photoreceptor cis-regulatory elements and their relation to Onecut1. Neural Dev. 2018 11 22; 13(1):26.

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Liang B, Wang X, Bian Y, Yang H, Liu M, Bai R, Yang Z, Xiao C. Angiotensin-(1-7) upregulates expression of adenosine triphosphate-binding cassette transporter A1 and adenosine triphosphate-binding cassette transporter G1 through the Mas receptor through the liver X receptor alpha signalling pathway in THP-1 macrophages treated with angiotensin-II. Clin Exp Pharmacol Physiol. 2014 Dec; 41(12):1023-30.

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Liang H, Zhong Y, Zhou S, Li QQ. Palmitic acid-induced apoptosis in pancreatic ?-cells is increased by liver X receptor agonist and attenuated by eicosapentaenoate. In Vivo. 2011 Sep-Oct; 25(5):711-8.

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Villacorta L, Garcia-Barrio MT, Chen YE. Transcriptional regulation of peroxisome proliferator-activated receptors and liver X receptors. Curr Atheroscler Rep. 2007 Sep; 9(3):230-7.

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Liu Y, Yan C, Wang Y, Nakagawa Y, Nerio N, Anghel A, Lutfy K, Friedman TC. Liver X receptor agonist T0901317 inhibition of glucocorticoid receptor expression in hepatocytes may contribute to the amelioration of diabetic syndrome in db/db mice. Endocrinology. 2006 Nov; 147(11):5061-8.

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Morello F, de Boer RA, Steffensen KR, Gnecchi M, Chisholm JW, Boomsma F, Anderson LM, Lawn RM, Gustafsson JA, Lopez-Ilasaca M, Pratt RE, Dzau VJ. Liver X receptors alpha and beta regulate renin expression in vivo. J Clin Invest. 2005 Jul; 115(7):1913-22.

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Anderson LM, Choe SE, Yukhananov RY, Hopfner RL, Church GM, Pratt RE, Dzau VJ. Identification of a novel set of genes regulated by a unique liver X receptor-alpha -mediated transcription mechanism. J Biol Chem. 2003 Apr 25; 278(17):15252-60.

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