Heterogeneous-Nuclear Ribonucleoprotein K
"Heterogeneous-Nuclear Ribonucleoprotein K" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A heterogeneous-nuclear ribonucleoprotein found in the CELL NUCLEUS and the CYTOPLASM. Heterogeneous-nuclear ribonucleoprotein K has been implicated in the regulation of gene expression at nearly all levels: GENETIC TRANSCRIPTION; mRNA processing (RNA PROCESSING, POST-TRANSCRIPTIONAL), mRNA transport, mRNA stability, and translation (TRANSLATION, GENETIC). The hnRNP protein has a strong affinity for polypyrimidine-rich RNA and for single-stranded polypyrimidine-rich DNA. Multiple hnRNP K protein isoforms exist due to alternative splicing and display different nucleic-acid-binding properties.
| Descriptor ID |
D034641
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| MeSH Number(s) |
D12.776.157.725.813.750.500 D12.776.260.268 D12.776.664.962.813.750.500
|
| Concept/Terms |
hnRNP K Protein- hnRNP K Protein
- Heterogeneous Nuclear Ribonucleoprotein Particle K Protein
- dC-Stretch-Binding Protein
- dC Stretch Binding Protein
|
Below are MeSH descriptors whose meaning is more general than "Heterogeneous-Nuclear Ribonucleoprotein K".
Below are MeSH descriptors whose meaning is more specific than "Heterogeneous-Nuclear Ribonucleoprotein K".
This graph shows the total number of publications written about "Heterogeneous-Nuclear Ribonucleoprotein K" by people in this website by year, and whether "Heterogeneous-Nuclear Ribonucleoprotein K" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2009 | 1 | 0 | 1 |
| 2018 | 0 | 1 | 1 |
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Below are the most recent publications written about "Heterogeneous-Nuclear Ribonucleoprotein K" by people in Profiles.
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Ali MM, Akhade VS, Kosalai ST, Subhash S, Statello L, Meryet-Figuiere M, Abrahamsson J, Mondal T, Kanduri C. PAN-cancer analysis of S-phase enriched lncRNAs identifies oncogenic drivers and biomarkers. Nat Commun. 2018 02 28; 9(1):883.
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Mukhopadhyay NK, Kim J, Cinar B, Ramachandran A, Hager MH, Di Vizio D, Adam RM, Rubin MA, Raychaudhuri P, De Benedetti A, Freeman MR. Heterogeneous nuclear ribonucleoprotein K is a novel regulator of androgen receptor translation. Cancer Res. 2009 Mar 15; 69(6):2210-8.