Drug Contamination

"Drug Contamination" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure, which enables searching at various levels of specificity.

MeSH information

Definition | Details | More General Concepts | Related Concepts | More Specific Concepts

The presence of organisms, or any foreign material that makes a drug preparation impure.

Descriptor ID	D004340
MeSH Number(s)	N06.850.360
Concept/Terms	Drug Contamination Drug Contamination Contamination, Drug Contaminations, Drug Drug Contaminations Drug Impurity Drug Impurity Drug Adulteration Drug Adulteration Adulteration, Drug Adulterations, Drug Drug Adulterations

Below are MeSH descriptors whose meaning is more general than "Drug Contamination".

Health Care [N]
Environment and Public Health [N06]
Public Health [N06.850]
Drug Contamination [N06.850.360]

Below are MeSH descriptors whose meaning is more specific than "Drug Contamination".

publications

Timeline | Most Recent

This graph shows the total number of publications written about "Drug Contamination" by people in this website by year, and whether "Drug Contamination" was a major or minor topic of these publications.

Bar chart showing 11 publications over 7 distinct years, with a maximum of 4 publications in 2024

To see the data from this visualization as text, click here.

Year	Major Topic	Minor Topic	Total
1997	0	1	1
2002	0	1	1
2012	0	1	1
2014	0	1	1
2016	0	2	2
2024	3	1	4
2025	1	0	1

Below are the most recent publications written about "Drug Contamination" by people in Profiles.

Kodishala RK, Sayyad K, Kowtharapu LP, Konduru N, Mondal T, Varkolu M, Gundekari S. Unspecified degradation impurities identification and characterization in bilastine and montelukast tablet formulations by using UPLC and LCMS/MS: Robustness by design expert and green assessment. Ann Pharm Fr. 2025 Nov; 83(6):1092-1113.

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Dicker F, Lothet E, Schwarz E, Aldy K, Brent J, Wax P, Culbreth R, Campleman S, Krotulski A, Logan B, Amaducci A, Judge B, Levine M, Calello D, Shulman J, Hughes A, Hendrickson RG, Meaden CW, Manini AF. Tramadol as a fentanyl adulterant: Prevalence and management in a ToxIC Fentalog study prospective cohort. Am J Emerg Med. 2025 Mar; 89:169-173.

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Sayyad K, Kowtharapu LP, Mondal T. Headspace Gas Chromatography-Mass Spectrometry Method for Determination of Class-I Residual Solvents in Several Drug Substances: Method Evaluation by Quality by Design Statistical Tool. J AOAC Int. 2024 Nov 01; 107(6):921-933.

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Kousrali S, Kowtharapu LP, Mondal T. Gas chromatography mass spectrometer determination of dimethylamine impurity in N,N-dimethylformamide solvent by derivatization of N,N-dimethylbenzamide with benzoyl chloride agent. Biomed Chromatogr. 2024 Aug; 38(8):e5920.

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Kousrali S, Kowtharapu LP, Mondal T. Analytical determination of ethylenediamine impurity in tripelennamine hydrochloride by gas chromatography-mass spectrometry using phthalaldehyde as the derivatizing agent. Biomed Chromatogr. 2024 Jun; 38(6):e5850.

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El-Zaher AA, Elkady EF, Elwy HM, Saleh MA. Simultaneous Determination of Metformin, Glipizide, Repaglinide, and Glimepiride or Metformin and Pioglitazone by a Validated LC Method: Application in the Presence of Metformin Impurity (1-Cyanoguanidine). J AOAC Int. 2016 Jul; 99(4):957-963.

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Syvertsen JL, Ohaga S, Agot K, Dimova M, Guise A, Rhodes T, Wagner KD. An ethnographic exploration of drug markets in Kisumu, Kenya. Int J Drug Policy. 2016 Apr; 30:82-90.

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Kalita M, Balivada S, Swarup VP, Mencio C, Raman K, Desai UR, Troyer D, Kuberan B. A nanosensor for ultrasensitive detection of oversulfated chondroitin sulfate contaminant in heparin. J Am Chem Soc. 2014 Jan 15; 136(2):554-7.

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Ruiz-Col?n K, Mart?nez MA, Silva-Torres LA, Chavez-Arias C, Mel?ndez-Negr?n M, Conte-Miller MS, Bloom-Oquendo J. Simultaneous determination of xylazine, free morphine, codeine, 6-acetylmorphine, cocaine and benzoylecgonine in postmortem blood by UPLC-MS-MS. J Anal Toxicol. 2012 Jun; 36(5):319-26.

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Carbone M, Pass HI. Re: Debate on the link between SV40 and human cancer continues. J Natl Cancer Inst. 2002 Feb 06; 94(3):229-30.

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