Macrophage Colony-Stimulating Factor
"Macrophage Colony-Stimulating Factor" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A mononuclear phagocyte colony-stimulating factor (M-CSF) synthesized by mesenchymal cells. The compound stimulates the survival, proliferation, and differentiation of hematopoietic cells of the monocyte-macrophage series. M-CSF is a disulfide-bonded glycoprotein dimer with a MW of 70 kDa. It binds to a specific high affinity receptor (RECEPTOR, MACROPHAGE COLONY-STIMULATING FACTOR).
Descriptor ID |
D016173
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MeSH Number(s) |
D12.644.276.374.410.240.500 D12.776.395.240.500 D12.776.467.374.410.240.500 D23.529.374.410.240.500
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Concept/Terms |
Macrophage Colony-Stimulating Factor- Macrophage Colony-Stimulating Factor
- M-CSF
- CSF-1
- CSF-M
- Colony-Stimulating Factor 1
- Colony Stimulating Factor 1
- Colony-Stimulating Factor, Macrophage
- Colony Stimulating Factor, Macrophage
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Below are MeSH descriptors whose meaning is more general than "Macrophage Colony-Stimulating Factor".
Below are MeSH descriptors whose meaning is more specific than "Macrophage Colony-Stimulating Factor".
This graph shows the total number of publications written about "Macrophage Colony-Stimulating Factor" by people in this website by year, and whether "Macrophage Colony-Stimulating Factor" was a major or minor topic of these publications.
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Year | Major Topic | Minor Topic | Total |
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1998 | 0 | 1 | 1 |
2002 | 1 | 2 | 3 |
2016 | 1 | 0 | 1 |
2020 | 2 | 0 | 2 |
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Below are the most recent publications written about "Macrophage Colony-Stimulating Factor" by people in Profiles.
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Sinha SK, Miikeda A, Fouladian Z, Mehrabian M, Edillor C, Shih D, Zhou Z, Paul MK, Charugundla S, Davis RC, Rajavashisth TB, Lusis AJ. Local M-CSF (Macrophage Colony-Stimulating Factor) Expression Regulates Macrophage Proliferation and Apoptosis in Atherosclerosis. Arterioscler Thromb Vasc Biol. 2021 01; 41(1):220-233.
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Hu X, Li S, Doycheva DM, Huang L, Lenahan C, Liu R, Huang J, Gao L, Tang J, Zuo G, Zhang JH. Rh-CSF1 Attenuates Oxidative Stress and Neuronal Apoptosis via the CSF1R/PLCG2/PKA/UCP2 Signaling Pathway in a Rat Model of Neonatal HIE. Oxid Med Cell Longev. 2020; 2020:6801587.
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Mishra V, Sinha SK, Rajavashisth TB. Role of macrophage colony-stimulating factor in the development of neointimal thickening following arterial injury. Cardiovasc Pathol. 2016 Jul-Aug; 25(4):284-292.
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Uzui H, Harpf A, Liu M, Doherty TM, Shukla A, Chai NN, Tripathi PV, Jovinge S, Wilkin DJ, Asotra K, Shah PK, Rajavashisth TB. Increased expression of membrane type 3-matrix metalloproteinase in human atherosclerotic plaque: role of activated macrophages and inflammatory cytokines. Circulation. 2002 Dec 10; 106(24):3024-30.
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Finkelstein A, Makkar R, Doherty TM, Vegesna VR, Tripathi P, Liu M, Bergman J, Fishbein M, Hausleiter J, Takizawa K, Rukshin V, Shah PK, Rajavashisth TB. Increased expression of macrophage colony-stimulating factor after coronary artery balloon injury is inhibited by intracoronary brachytherapy. Circulation. 2002 May 21; 105(20):2411-5.
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Doherty TM, Uzui H, Fitzpatrick LA, Tripathi PV, Dunstan CR, Asotra K, Rajavashisth TB. Rationale for the role of osteoclast-like cells in arterial calcification. FASEB J. 2002 Apr; 16(6):577-82.
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Slayton WB, Juul SE, Calhoun DA, Li Y, Braylan RC, Christensen RD. Hematopoiesis in the liver and marrow of human fetuses at 5 to 16 weeks postconception: quantitative assessment of macrophage and neutrophil populations. Pediatr Res. 1998 Jun; 43(6):774-82.
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Adunyah SE. Granulocyte-macrophage colony stimulating factor stimulates rapid phosphorylation of proteins on tyrosines in human U937 and HL-60 leukemic cells. Biochem Biophys Res Commun. 1993 Jun 30; 193(3):890-6.
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Ernst TJ, Ritchie AR, O'Rourke R, Griffin JD. Colony-stimulating factor gene expression in human acute myeloblastic leukemia cells is posttranscriptionally regulated. Leukemia. 1989 Sep; 3(9):620-5.