Repressor Proteins

RCMI Coordinating Center (RCMI CC)

"Repressor Proteins" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure, which enables searching at various levels of specificity.

MeSH information

Definition | Details | More General Concepts | Related Concepts | More Specific Concepts

Proteins which maintain the transcriptional quiescence of specific GENES or OPERONS. Classical repressor proteins are DNA-binding proteins that are normally bound to the OPERATOR REGION of an operon, or the ENHANCER SEQUENCES of a gene until a signal occurs that causes their release.

Descriptor ID	D012097
MeSH Number(s)	D12.776.260.703 D12.776.930.780
Concept/Terms	Repressor Proteins Repressor Proteins Proteins, Repressor Transcriptional Silencing Factors Transcriptional Silencing Factors Silencing Factors, Transcriptional Repressor Molecules Repressor Molecules

Below are MeSH descriptors whose meaning is more general than "Repressor Proteins".

Chemicals and Drugs [D]
Amino Acids, Peptides, and Proteins [D12]
Proteins [D12.776]
DNA-Binding Proteins [D12.776.260]
Repressor Proteins [D12.776.260.703]
Transcription Factors [D12.776.930]
Repressor Proteins [D12.776.930.780]

Below are MeSH descriptors whose meaning is related to "Repressor Proteins".

Below are MeSH descriptors whose meaning is more specific than "Repressor Proteins".

publications

Timeline | Most Recent

This graph shows the total number of publications written about "Repressor Proteins" by people in this website by year, and whether "Repressor Proteins" was a major or minor topic of these publications.

Bar chart showing 201 publications over 30 distinct years, with a maximum of 20 publications in 2005

To see the data from this visualization as text, click here.

Year	Major Topic	Minor Topic	Total
1996	3	0	3
1997	0	1	1
1998	0	1	1
1999	2	0	2
2000	1	1	2
2001	1	0	1
2002	6	1	7
2003	3	7	10
2004	5	6	11
2005	17	3	20
2006	4	3	7
2007	6	5	11
2008	3	3	6
2009	5	0	5
2010	4	3	7
2011	3	1	4
2012	7	2	9
2013	6	5	11
2014	5	7	12
2015	5	4	9
2016	6	3	9
2017	6	1	7
2018	3	4	7
2019	5	3	8
2020	7	1	8
2021	9	3	12
2022	1	1	2
2023	0	2	2
2024	1	3	4
2025	3	0	3

Below are the most recent publications written about "Repressor Proteins" by people in Profiles.

Aubee JI, Williams K, Adigun A, Olusanya O, Nurse J, Thompson KM. Post-Transcriptional Regulation of the MiaA Prenyl Transferase by CsrA and the Small RNA CsrB in Escherichia coli. Int J Mol Sci. 2025 Jun 24; 26(13).

View in: PubMed
Digman A, Pajarillo E, Kim S, Ajayi I, Son DS, Aschner M, Lee E. Tamoxifen induces protection against manganese toxicity by REST upregulation via the ER-a/Wnt/?-catenin pathway in neuronal cells. J Biol Chem. 2025 06; 301(6):108529.

View in: PubMed
Kim S, Pajarillo E, Digman A, Ajayi I, Son DS, Aschner M, Lee E. Role of dopaminergic RE1-silencing transcription factor (REST) in manganese-induced behavioral deficits and dysregulating dopaminergic and serotonergic neurotransmission in mice. Neurotoxicology. 2025 May; 108:57-68.

View in: PubMed
Pajarillo E, Kim S, Digman A, Ajayi I, Nyarko-Danquah I, Son DS, Aschner M, Lee E. Dopaminergic REST/NRSF is protective against manganese-induced neurotoxicity in mice. J Biol Chem. 2024 09; 300(9):107707.

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Qin M, Fan W, Li L, Xu T, Zhang H, Chen F, Man J, Kombe AJK, Zhang J, Shi Y, Yao X, Yang Z, Hou Z, Ruan K, Liu D. PRMT1 and TDRD3 promote stress granule assembly by rebuilding the protein-RNA interaction network. Int J Biol Macromol. 2024 Oct; 277(Pt 3):134411.

View in: PubMed
Yoshida S, Kawamura A, Aoki K, Wiriyasermkul P, Sugimoto S, Tomiyoshi J, Tajima A, Ishida Y, Katoh Y, Tsukada T, Tsuneoka Y, Yamada K, Nagamori S, Nakayama K, Yoshida K. Positive regulation of Hedgehog signaling via phosphorylation of GLI2/GLI3 by DYRK2 kinase. Proc Natl Acad Sci U S A. 2024 Jul 09; 121(28):e2320070121.

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Brown LK, Kanagasabai T, Li G, Celada SI, Rumph JT, Adunyah SE, Stewart LV, Chen Z. Co-targeting SKP2 and KDM5B inhibits prostate cancer progression by abrogating AKT signaling with induction of senescence and apoptosis. Prostate. 2024 Jun; 84(9):877-887.

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Givony T, Leshkowitz D, Del Castillo D, Nevo S, Kadouri N, Dassa B, Gruper Y, Khalaila R, Ben-Nun O, Gome T, Dobe? J, Ben-Dor S, Kedmi M, Keren-Shaul H, Heffner-Krausz R, Porat Z, Golani O, Addadi Y, Brenner O, Lo DD, Goldfarb Y, Abramson J. Thymic mimetic cells function beyond self-tolerance. Nature. 2023 10; 622(7981):164-172.

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Casasnovas-Nieves JJ, Rodr?guez Y, Franco HL, Cadilla CL. Mechanisms of Regulation of the CHRDL1 Gene by the TWIST2 and ADD1/SREBP1c Transcription Factors. Genes (Basel). 2023 Aug 30; 14(9).

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Sun Y, Bae YE, Zhu J, Zhang Z, Zhong H, Yu J, Wu C, Wu L. A splicing transcriptome-wide association study identifies novel altered splicing for Alzheimer's disease susceptibility. Neurobiol Dis. 2023 08; 184:106209.

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