beta Catenin

"beta Catenin" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure, which enables searching at various levels of specificity.

MeSH information

Definition | Details | More General Concepts | Related Concepts | More Specific Concepts

A multi-functional catenin that participates in CELL ADHESION and nuclear signaling. Beta catenin binds CADHERINS and helps link their cytoplasmic tails to the ACTIN in the CYTOSKELETON via ALPHA CATENIN. It also serves as a transcriptional co-activator and downstream component of WNT PROTEIN-mediated SIGNAL TRANSDUCTION PATHWAYS.

Descriptor ID	D051176
MeSH Number(s)	D12.776.091.249 D12.776.220.145.500 D12.776.930.130
Concept/Terms	beta Catenin beta Catenin Catenin, beta beta-Catenin

Below are MeSH descriptors whose meaning is more general than "beta Catenin".

Chemicals and Drugs [D]
Amino Acids, Peptides, and Proteins [D12]
Proteins [D12.776]
Armadillo Domain Proteins [D12.776.091]
beta Catenin [D12.776.091.249]
Cytoskeletal Proteins [D12.776.220]
Catenins [D12.776.220.145]
beta Catenin [D12.776.220.145.500]
Transcription Factors [D12.776.930]
beta Catenin [D12.776.930.130]

Below are MeSH descriptors whose meaning is related to "beta Catenin".

Below are MeSH descriptors whose meaning is more specific than "beta Catenin".

publications

Timeline | Most Recent

This graph shows the total number of publications written about "beta Catenin" by people in this website by year, and whether "beta Catenin" was a major or minor topic of these publications.

Bar chart showing 53 publications over 22 distinct years, with a maximum of 5 publications in 2014 and 2017

To see the data from this visualization as text, click here.

Year	Major Topic	Minor Topic	Total
2001	0	1	1
2002	0	1	1
2003	0	3	3
2005	1	1	2
2006	2	0	2
2008	2	0	2
2009	1	1	2
2010	1	2	3
2011	2	1	3
2012	1	1	2
2013	2	1	3
2014	3	2	5
2015	1	1	2
2016	1	0	1
2017	2	3	5
2018	0	3	3
2019	1	0	1
2020	3	1	4
2021	1	2	3
2022	1	1	2
2024	0	1	1
2025	1	1	2

Below are the most recent publications written about "beta Catenin" by people in Profiles.

Zhu X, Zhang X, Qin Y, Chen Y, Feng X, Deng S, Hu F, Yuan Y, Luo X, Du K, Chang S, Fan X, Ashktorab H, Smoot D, Jin Z, Peng Y. Circular RNA circATM binds PARP1 to suppress Wnt/?-catenin signaling and induce cell cycle arrest in gastric cancer cells. J Adv Res. 2026 Feb; 80:609-625.

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Digman A, Pajarillo E, Kim S, Ajayi I, Son DS, Aschner M, Lee E. Tamoxifen induces protection against manganese toxicity by REST upregulation via the ER-a/Wnt/?-catenin pathway in neuronal cells. J Biol Chem. 2025 06; 301(6):108529.

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Callaway DJE, Nicholl ID, Shi B, Reyes G, Farago B, Bu Z. Nanoscale dynamics of the cadherin-catenin complex bound to vinculin revealed by neutron spin echo spectroscopy. Proc Natl Acad Sci U S A. 2024 Sep 24; 121(39):e2408459121.

View in: PubMed
Tang Y, Wang C, Desamero MJM, Kok MK, Chambers JK, Uchida K, Kominami Y, Ushio H, Cervancia C, Estacio MA, Kyuwa S, Kakuta S. The Philippines stingless bee propolis promotes hair growth through activation of Wnt/?-catenin signaling pathway. Exp Anim. 2023 Feb 21; 72(1):132-139.

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Arun A, Rayford KJ, Cooley A, Rana T, Rachakonda G, Villalta F, Pratap S, Lima MF, Sheibani N, Nde PN. Thrombospondin-1 expression and modulation of Wnt and hippo signaling pathways during the early phase of Trypanosoma cruzi infection of heart endothelial cells. PLoS Negl Trop Dis. 2022 01; 16(1):e0010074.

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He W, Lu Q, Sherchan P, Huang L, Hu X, Zhang JH, Dai H, Tang J. Activation of Frizzled-7 attenuates blood-brain barrier disruption through Dvl/?-catenin/WISP1 signaling pathway after intracerebral hemorrhage in mice. Fluids Barriers CNS. 2021 Sep 26; 18(1):44.

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Fu Y, Katsaros D, Biglia N, Wang Z, Pagano I, Tius M, Tiirikainen M, Rosser C, Yang H, Yu H. Vitamin D receptor upregulates lncRNA TOPORS-AS1 which inhibits the Wnt/?-catenin pathway and associates with favorable prognosis of ovarian cancer. Sci Rep. 2021 04 05; 11(1):7484.

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Sayaman RW, Saad M, Thorsson V, Hu D, Hendrickx W, Roelands J, Porta-Pardo E, Mokrab Y, Farshidfar F, Kirchhoff T, Sweis RF, Bathe OF, Heimann C, Campbell MJ, Stretch C, Huntsman S, Graff RE, Syed N, Radvanyi L, Shelley S, Wolf D, Marincola FM, Ceccarelli M, Galon J, Ziv E, Bedognetti D. Germline genetic contribution to the immune landscape of cancer. Immunity. 2021 02 09; 54(2):367-386.e8.

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Peng Y, Zhang X, Lin H, Deng S, Qin Y, Yuan Y, Feng X, Wang J, Chen W, Hu F, Yan R, Zhao Y, Cheng Y, Wei Y, Fan X, Ashktorab H, Smoot D, Li S, Meltzer SJ, Jin Z. SUFU mediates EMT and Wnt/?-catenin signaling pathway activation promoted by miRNA-324-5p in human gastric cancer. Cell Cycle. 2020 10; 19(20):2720-2733.

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Jun SY, Brown AJ, Chua NK, Yoon JY, Lee JJ, Yang JO, Jang I, Jeon SJ, Choi TI, Kim CH, Kim NS. Reduction of Squalene Epoxidase by Cholesterol Accumulation Accelerates Colorectal Cancer Progression and Metastasis. Gastroenterology. 2021 03; 160(4):1194-1207.e28.

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