Nitric Oxide

"Nitric Oxide" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure, which enables searching at various levels of specificity.

MeSH information

Definition | Details | More General Concepts | Related Concepts | More Specific Concepts

A free radical gas produced endogenously by a variety of mammalian cells, synthesized from ARGININE by NITRIC OXIDE SYNTHASE. Nitric oxide is one of the ENDOTHELIUM-DEPENDENT RELAXING FACTORS released by the vascular endothelium and mediates VASODILATION. It also inhibits platelet aggregation, induces disaggregation of aggregated platelets, and inhibits platelet adhesion to the vascular endothelium. Nitric oxide activates cytosolic GUANYLATE CYCLASE and thus elevates intracellular levels of CYCLIC GMP.

Descriptor ID	D009569
MeSH Number(s)	D01.339.387 D01.625.550.500 D01.625.700.500 D01.650.550.587.600
Concept/Terms	Nitric Oxide Nitric Oxide Oxide, Nitric Nitrogen Monoxide Monoxide, Nitrogen Nitric Oxide, Endothelium-Derived Endothelium-Derived Nitric Oxide Nitric Oxide, Endothelium Derived Endogenous Nitrate Vasodilator Nitrate Vasodilator, Endogenous Vasodilator, Endogenous Nitrate Mononitrogen Monoxide Monoxide, Mononitrogen

Below are MeSH descriptors whose meaning is more general than "Nitric Oxide".

Chemicals and Drugs [D]
Inorganic Chemicals [D01]
Free Radicals [D01.339]
Nitric Oxide [D01.339.387]
Nitrogen Compounds [D01.625]
Nitrogen Oxides [D01.625.550]
Nitric Oxide [D01.625.550.500]
Reactive Nitrogen Species [D01.625.700]
Nitric Oxide [D01.625.700.500]
Oxygen Compounds [D01.650]
Oxides [D01.650.550]
Nitrogen Oxides [D01.650.550.587]
Nitric Oxide [D01.650.550.587.600]

Below are MeSH descriptors whose meaning is related to "Nitric Oxide".

Below are MeSH descriptors whose meaning is more specific than "Nitric Oxide".

publications

Timeline | Most Recent

This graph shows the total number of publications written about "Nitric Oxide" by people in this website by year, and whether "Nitric Oxide" was a major or minor topic of these publications.

Bar chart showing 222 publications over 28 distinct years, with a maximum of 19 publications in 2010

To see the data from this visualization as text, click here.

Year	Major Topic	Minor Topic	Total
1995	1	1	2
1996	1	0	1
1998	3	0	3
1999	0	1	1
2000	1	1	2
2001	0	1	1
2002	6	4	10
2003	7	7	14
2004	8	7	15
2005	9	8	17
2006	7	6	13
2007	7	6	13
2008	4	5	9
2009	7	3	10
2010	8	11	19
2011	7	5	12
2012	2	7	9
2013	3	8	11
2014	1	10	11
2015	3	8	11
2016	4	6	10
2017	3	3	6
2018	1	5	6
2019	3	0	3
2020	2	1	3
2021	2	1	3
2022	1	2	3
2023	1	3	4

Below are the most recent publications written about "Nitric Oxide" by people in Profiles.

Silva BJA, Krogstad PA, Teles RMB, Andrade PR, Rajfer J, Ferrini MG, Yang OO, Bloom BR, Modlin RL. IFN-?-mediated control of SARS-CoV-2 infection through nitric oxide. Front Immunol. 2023; 14:1284148.

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Barber K, Mendonca P, Evans JA, Soliman KFA. Antioxidant and Anti-Inflammatory Mechanisms of Cardamonin through Nrf2 Activation and NF-kB Suppression in LPS-Activated BV-2 Microglial Cells. Int J Mol Sci. 2023 Jun 29; 24(13).

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Tuluri F, Remata R, Walters WL, Tchounwou PB. Impact of Regional Mobility on Air Quality during COVID-19 Lockdown in Mississippi, USA Using Machine Learning. Int J Environ Res Public Health. 2023 05 31; 20(11).

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Gouveia J?nior FS, Silveira JAM, Holanda TM, Marinho AD, Ridnour LA, Wink DA, de Siqueira RJB, Monteiro HSA, Sousa EHS, Lopes LGF. New nitrosyl ruthenium complexes with combined activities for multiple cardiovascular disorders. Dalton Trans. 2023 Apr 25; 52(16):5176-5191.

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Edosuyi O, Adesuyi A, Choi M, Igbe I, Oyekan A. Malate reduced blood pressure and exerted differential effects on renal hemodynamics; role of the nitric oxide system and renal epithelial sodium channels (ENaC). Eur J Pharmacol. 2023 Jan 05; 938:175441.

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Ajibade TO, Awodele OA, Tijani MO, Adejumobi OA, Adetona MO, Oyagbemi AA, Adedapo AD, Omobowale TO, Aro AO, Ola-Davies OE, Saba AB, Adedapo AA, Nkadimeng SM, McGaw LJ, Kayoka-Kabongo PN, Oguntibeju OO, Yakubu MA. L-arginine and lisinopril supplementation protects against sodium fluoride-induced nephrotoxicity and hypertension by suppressing mineralocorticoid receptor and angiotensin-converting enzyme 3 activity. Environ Sci Pollut Res Int. 2023 Feb; 30(9):23263-23275.

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Ikwu I, Nicolas LG, Mehari A, Gillum RF. Fractional exhaled nitric oxide and mortality in asthma and chronic obstructive pulmonary disease in a national cohort aged 40 years and older. Respir Med. 2022 07; 198:106879.

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Craighead DH, Heinbockel TC, Freeberg KA, Rossman MJ, Jackman RA, Jankowski LR, Hamilton MN, Ziemba BP, Reisz JA, D'Alessandro A, Brewster LM, DeSouza CA, You Z, Chonchol M, Bailey EF, Seals DR. Time-Efficient Inspiratory Muscle Strength Training Lowers Blood Pressure and Improves Endothelial Function, NO Bioavailability, and Oxidative Stress in Midlife/Older Adults With Above-Normal Blood Pressure. J Am Heart Assoc. 2021 07 06; 10(13):e020980.

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Bartosch AMW, Mathews R, Mahmoud MM, Cancel LM, Haq ZS, Tarbell JM. Heparan sulfate proteoglycan glypican-1 and PECAM-1 cooperate in shear-induced endothelial nitric oxide production. Sci Rep. 2021 05 31; 11(1):11386.

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Sampath C, Wilus D, Tabatabai M, Freeman ML, Gangula PR. Mechanistic role of antioxidants in rescuing delayed gastric emptying in high fat diet induced diabetic female mice. Biomed Pharmacother. 2021 May; 137:111370.

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