"Nitric Oxide" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A free radical gas produced endogenously by a variety of mammalian cells, synthesized from ARGININE by NITRIC OXIDE SYNTHASE. Nitric oxide is one of the ENDOTHELIUM-DEPENDENT RELAXING FACTORS released by the vascular endothelium and mediates VASODILATION. It also inhibits platelet aggregation, induces disaggregation of aggregated platelets, and inhibits platelet adhesion to the vascular endothelium. Nitric oxide activates cytosolic GUANYLATE CYCLASE and thus elevates intracellular levels of CYCLIC GMP.
| Descriptor ID |
D009569
|
| MeSH Number(s) |
D01.339.387 D01.625.550.500 D01.625.700.500 D01.650.550.587.600
|
| Concept/Terms |
Nitric Oxide- Nitric Oxide
- Oxide, Nitric
- Nitrogen Monoxide
- Monoxide, Nitrogen
- Nitric Oxide, Endothelium-Derived
- Endothelium-Derived Nitric Oxide
- Nitric Oxide, Endothelium Derived
- Endogenous Nitrate Vasodilator
- Nitrate Vasodilator, Endogenous
- Vasodilator, Endogenous Nitrate
- Mononitrogen Monoxide
- Monoxide, Mononitrogen
|
Below are MeSH descriptors whose meaning is more general than "Nitric Oxide".
Below are MeSH descriptors whose meaning is more specific than "Nitric Oxide".
This graph shows the total number of publications written about "Nitric Oxide" by people in this website by year, and whether "Nitric Oxide" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1995 | 1 | 1 | 2 |
| 1996 | 1 | 0 | 1 |
| 1997 | 0 | 1 | 1 |
| 1998 | 3 | 0 | 3 |
| 1999 | 0 | 1 | 1 |
| 2000 | 1 | 1 | 2 |
| 2001 | 0 | 5 | 5 |
| 2002 | 10 | 8 | 18 |
| 2003 | 8 | 9 | 17 |
| 2004 | 8 | 7 | 15 |
| 2005 | 9 | 8 | 17 |
| 2006 | 7 | 6 | 13 |
| 2007 | 7 | 6 | 13 |
| 2008 | 5 | 5 | 10 |
| 2009 | 7 | 4 | 11 |
| 2010 | 8 | 11 | 19 |
| 2011 | 7 | 5 | 12 |
| 2012 | 2 | 8 | 10 |
| 2013 | 3 | 8 | 11 |
| 2014 | 1 | 10 | 11 |
| 2015 | 3 | 8 | 11 |
| 2016 | 3 | 6 | 9 |
| 2017 | 3 | 3 | 6 |
| 2018 | 1 | 5 | 6 |
| 2019 | 3 | 1 | 4 |
| 2020 | 2 | 1 | 3 |
| 2021 | 2 | 1 | 3 |
| 2022 | 1 | 2 | 3 |
| 2023 | 1 | 5 | 6 |
| 2024 | 1 | 0 | 1 |
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Below are the most recent publications written about "Nitric Oxide" by people in Profiles.
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Sampath C, Chukkapalli SS, Raju AV, Alluri LSC, Srisai D, Gangula PR. Cinnamaldehyde Protects against P. gingivalis Induced Intestinal Epithelial Barrier Dysfunction in IEC-6 Cells via the PI3K/Akt-Mediated NO/Nrf2 Signaling Pathway. Int J Mol Sci. 2024 Apr 26; 25(9).
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Silva BJA, Krogstad PA, Teles RMB, Andrade PR, Rajfer J, Ferrini MG, Yang OO, Bloom BR, Modlin RL. IFN-?-mediated control of SARS-CoV-2 infection through nitric oxide. Front Immunol. 2023; 14:1284148.
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Barber K, Mendonca P, Evans JA, Soliman KFA. Antioxidant and Anti-Inflammatory Mechanisms of Cardamonin through Nrf2 Activation and NF-kB Suppression in LPS-Activated BV-2 Microglial Cells. Int J Mol Sci. 2023 Jun 29; 24(13).
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Tuluri F, Remata R, Walters WL, Tchounwou PB. Impact of Regional Mobility on Air Quality during COVID-19 Lockdown in Mississippi, USA Using Machine Learning. Int J Environ Res Public Health. 2023 05 31; 20(11).
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Gouveia J?nior FS, Silveira JAM, Holanda TM, Marinho AD, Ridnour LA, Wink DA, de Siqueira RJB, Monteiro HSA, Sousa EHS, Lopes LGF. New nitrosyl ruthenium complexes with combined activities for multiple cardiovascular disorders. Dalton Trans. 2023 Apr 25; 52(16):5176-5191.
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Dokunmu TM, Opara SC, Imaga NA, Awani OU, Enoma DO, Adelani BI. P53 Gene Expression and Nitric Oxide Levels after Artemisinin-Caffeine Treatment in Breast, Lungs and Liver of DMBA-Induced Tumorigenesis. Asian Pac J Cancer Prev. 2023 Feb 01; 24(2):451-458.
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Edosuyi O, Choi M, Edosuyi V, Igbe I, Oyekan A. Malate reduced kidney injury molecule (KIM-1) expression and selectively upregulated the renal nitric oxide production in obstructive nephropathy. Bratisl Lek Listy. 2023; 124(2):151-157.
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Edosuyi O, Adesuyi A, Choi M, Igbe I, Oyekan A. Malate reduced blood pressure and exerted differential effects on renal hemodynamics; role of the nitric oxide system and renal epithelial sodium channels (ENaC). Eur J Pharmacol. 2023 Jan 05; 938:175441.
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Ajibade TO, Awodele OA, Tijani MO, Adejumobi OA, Adetona MO, Oyagbemi AA, Adedapo AD, Omobowale TO, Aro AO, Ola-Davies OE, Saba AB, Adedapo AA, Nkadimeng SM, McGaw LJ, Kayoka-Kabongo PN, Oguntibeju OO, Yakubu MA. L-arginine and lisinopril supplementation protects against sodium fluoride-induced nephrotoxicity and hypertension by suppressing mineralocorticoid receptor and angiotensin-converting enzyme 3 activity. Environ Sci Pollut Res Int. 2023 Feb; 30(9):23263-23275.
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Ikwu I, Nicolas LG, Mehari A, Gillum RF. Fractional exhaled nitric oxide and mortality in asthma and chronic obstructive pulmonary disease in a national cohort aged 40 years and older. Respir Med. 2022 07; 198:106879.