Reactive Oxygen Species

"Reactive Oxygen Species" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure, which enables searching at various levels of specificity.

MeSH information

Definition | Details | More General Concepts | Related Concepts | More Specific Concepts

Molecules or ions formed by the incomplete one-electron reduction of oxygen. These reactive oxygen intermediates include SINGLET OXYGEN; SUPEROXIDES; PEROXIDES; HYDROXYL RADICAL; and HYPOCHLOROUS ACID. They contribute to the microbicidal activity of PHAGOCYTES, regulation of SIGNAL TRANSDUCTION and GENE EXPRESSION, and the oxidative damage to NUCLEIC ACIDS; PROTEINS; and LIPIDS.

Descriptor ID	D017382
MeSH Number(s)	D01.339.431 D01.650.775
Concept/Terms	Reactive Oxygen Species Reactive Oxygen Species Oxygen Species, Reactive Active Oxygen Oxygen, Active Oxygen Radicals Pro-Oxidants Pro Oxidants

Below are MeSH descriptors whose meaning is more general than "Reactive Oxygen Species".

Chemicals and Drugs [D]
Inorganic Chemicals [D01]
Free Radicals [D01.339]
Reactive Oxygen Species [D01.339.431]
Oxygen Compounds [D01.650]
Reactive Oxygen Species [D01.650.775]

Below are MeSH descriptors whose meaning is related to "Reactive Oxygen Species".

Below are MeSH descriptors whose meaning is more specific than "Reactive Oxygen Species".

publications

Timeline | Most Recent

This graph shows the total number of publications written about "Reactive Oxygen Species" by people in this website by year, and whether "Reactive Oxygen Species" was a major or minor topic of these publications.

Bar chart showing 374 publications over 28 distinct years, with a maximum of 26 publications in 2024

To see the data from this visualization as text, click here.

Year	Major Topic	Minor Topic	Total
1998	0	3	3
1999	0	2	2
2000	1	4	5
2001	2	2	4
2002	3	8	11
2003	2	5	7
2004	4	4	8
2005	1	6	7
2006	5	6	11
2007	2	17	19
2008	5	9	14
2009	1	14	15
2010	4	21	25
2011	4	14	18
2012	5	11	16
2013	3	13	16
2014	3	15	18
2015	3	18	21
2016	6	16	22
2017	3	14	17
2018	4	10	14
2019	0	17	17
2020	3	10	13
2021	3	7	10
2022	2	11	13
2023	0	12	12
2024	7	19	26
2025	0	10	10

Below are the most recent publications written about "Reactive Oxygen Species" by people in Profiles.

Lazarte JMS, Ofosu-Asante K, Tilghman SL, Lamango NS. PCAIs stimulate MAPK, PI3K/AKT pathways and ROS-Mediated apoptosis in aromatase inhibitor-resistant breast cancer cells while disrupting actin filaments and focal adhesion. Oncotarget. 2025 Jul 29; 16:621-641.

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Pal A, Bawali P, Brahma A, Rana SR, Mohapatra R, Chakraborty D, Poirah I, Samal S, Banerjee S, Smoot DT, Ashktorab H, Bhattacharyya A. RHOA-dependent regulation of mitochondrial remodeling and cell motility in hypoxia-exposed gastric epithelial cells. J Cell Sci. 2025 Jul 15; 138(14).

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Pacurari M, Cox I, Farah I. MiR-1 Is Regulated by Hydrogen Peroxide via MAPK and Limits Cell Migration and Invasion. Environ Toxicol. 2025 Nov; 40(11):1249-1260.

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Poirah I, Chakraborty S, Padhan PK, Mishra AK, Chakraborty D, Dixit P, Samal S, Rout N, Singh SP, Nath G, Smoot DT, Ashktorab H, Bhattacharyya A. Hypoxia and Hypoxia-Reoxygenation Potentiate Helicobacter pylori Infection and Gastric Epithelial Cell Proliferation. Cancer Med. 2025 May; 14(9):e70860.

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Aishwarya S, Torres GC, Lopez-Saenz JA, Gutierrez DA, Kumar S, Madarakhandi A, Metikurki B, Teraiya N, Aguilera RJ, Karki SS. Synthesis of novel pyridazine and pyrimidine linked pyrazole derivatives as DNA ligase 1 and IV inhibitors that induce apoptosis. Chem Biol Interact. 2025 Jun 01; 414:111509.

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Garcia-Baez J, Chaves-Negr?n I, Javadov S, Bazil JN, Chapa-Dubocq XR. Developing a physiologically relevant cell model of ferroptosis in cardiomyocytes. Free Radic Biol Med. 2025 Jun; 233:330-339.

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Scacco S, Acquaviva S, Fran?a Vieira E Silva F, Zhang JH, Lo Muzio L, Corso G, Caponio VCA, Reveglia P, Lecce L, Bizzoca ME, Sherchan P, Cantore S, Ballini A. Bioactivity and Neuroprotective Effects of Extra Virgin Olive Oil in a Mouse Model of Cerebral Ischemia: An In Vitro and In Vivo Study. Int J Mol Sci. 2025 Feb 19; 26(4).

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Marcantonio E, Burger AD, Chang KH, Hoffmann FW, Fu Y, Khadka VS, Smagghe BJ, Deng Y, Hoffmann PR, Prisic S. Zinc-limited Mycobacterium tuberculosis stimulate distinct responses in macrophages compared with standard zinc-replete bacteria. Infect Immun. 2025 03 11; 93(3):e0057824.

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Bradley CC, Walker-Franklin I, Kovach A, Sivaraman V, Onyenwoke RU. The effects of flavored vaped e-liquids on cultured human macrophages derived from the central and peripheral nervous systems. Toxicol In Vitro. 2025 Apr; 104:106013.

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ElMorsy SM, Gutierrez DA, Valdez S, Kumar J, Aguilera RJ, Noufal M, Chinnam S, Sarma H, Narayan M. Nitrogen doped carbon quantum dots: a multifaceted carbon nanomaterial that interferes in an amyloid-forming trajectory. J Mater Chem B. 2025 01 22; 13(4):1403-1411.

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