Antineoplastic Agents

"Antineoplastic Agents" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure, which enables searching at various levels of specificity.

MeSH information

Definition | Details | More General Concepts | Related Concepts | More Specific Concepts

Substances that inhibit or prevent the proliferation of NEOPLASMS.

Descriptor ID	D000970
MeSH Number(s)	D27.505.954.248
Concept/Terms	Antineoplastic Agents Antineoplastic Agents Agents, Antineoplastic Antineoplastic Drugs Drugs, Antineoplastic Antineoplastics Chemotherapeutic Anticancer Drug Drug, Chemotherapeutic Anticancer Antitumor Drugs Drugs, Antitumor Cancer Chemotherapy Agents Agents, Cancer Chemotherapy Chemotherapy Agents, Cancer Cancer Chemotherapy Drugs Chemotherapy Drugs, Cancer Drugs, Cancer Chemotherapy Chemotherapeutic Anticancer Agents Agents, Chemotherapeutic Anticancer Anticancer Agents Agents, Anticancer Antitumor Agents Agents, Antitumor

Below are MeSH descriptors whose meaning is more general than "Antineoplastic Agents".

Chemicals and Drugs [D]
Chemical Actions and Uses [D27]
Pharmacologic Actions [D27.505]
Therapeutic Uses [D27.505.954]
Antineoplastic Agents [D27.505.954.248]

Below are MeSH descriptors whose meaning is more specific than "Antineoplastic Agents".

publications

Timeline | Most Recent

This graph shows the total number of publications written about "Antineoplastic Agents" by people in this website by year, and whether "Antineoplastic Agents" was a major or minor topic of these publications.

Bar chart showing 742 publications over 30 distinct years, with a maximum of 58 publications in 2015

To see the data from this visualization as text, click here.

Year	Major Topic	Minor Topic	Total
1996	0	1	1
1997	3	1	4
1998	2	0	2
1999	1	1	2
2000	6	2	8
2001	7	1	8
2002	11	2	13
2003	9	8	17
2004	10	9	19
2005	10	10	20
2006	13	5	18
2007	22	5	27
2008	21	9	30
2009	11	8	19
2010	29	13	42
2011	27	13	40
2012	14	11	25
2013	31	10	41
2014	46	9	55
2015	48	10	58
2016	23	14	37
2017	36	5	41
2018	31	8	39
2019	28	6	34
2020	26	4	30
2021	21	6	27
2022	22	1	23
2023	12	0	12
2024	13	15	28
2025	20	2	22

Below are the most recent publications written about "Antineoplastic Agents" by people in Profiles.

Egbe Vydaline AO, Rozhkov S, Sosa G, Mallikaratchy P. Aptamers as target-specific recognition elements in drug delivery. Adv Drug Deliv Rev. 2025 Nov; 226:115685.

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Mondal T, Sahoo P, Nandi SK, Kundu S, Li M, Haldar N, Kabir R, Mitra K, Roy S, Das M, Ghosh CK. Opto-magnetic optimization enhances the multimodal therapeutic and diagnostic (UCL/T1-T2W MRI) potential of GdOF against MDA-MB-231. J Mater Chem B. 2025 Aug 13; 13(32):9993-10008.

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Acosta-Mercado J, Oliveras-Alsina A, Marcano-Maiz AI, Rivera-Torres AP, Cordero-Gimenez KT, Malavez-Cajigas S, Bayro MJ, Ramos-Benitez MJ, Pi?ero Cruz DM. Evaluating Naphthalene-Modified Metallosalen Complexes as Anticancer Agents. J Med Chem. 2025 Jul 24; 68(14):14300-14311.

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Srour AM, El-Bayaa MN, Temirak A, Alanzy AL, Awad HM, Saleh A, Saleh MG, El-Sayed WA. New benzimidazole-triazole glycoconjugates as anti-cancer agents and EGFR inhibitors. Sci Rep. 2025 Jul 15; 15(1):25514.

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Okpattah D, Karki A, Pillarsetty NVK, Harding WW. Synthesis and evaluation of aporphinoid 5-HT7AR ligands as inhibitors of PC3 prostate cancer cell growth. Bioorg Med Chem Lett. 2025 Dec 01; 128:130328.

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Chakrabarti S, Wagh C, Bagnall-Moreau C, Uddin F, Reiser J, Salas-Ramirez K, Ahles T, Hubbard K. Chemotherapy treatment alters DNA methylation patterns in the prefrontal cortex of female rat brain. Sci Rep. 2025 Jul 01; 15(1):20681.

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Mishra SD, Mendonca P, Kaur S, Soliman KFA. Silibinin Anticancer Effects Through the Modulation of the Tumor Immune Microenvironment in Triple-Negative Breast Cancer. Int J Mol Sci. 2025 Jun 28; 26(13).

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Kolawole OP, Pramanik A, Kasani-Akula P, Rai S, Janorkar S, Edorodion Z, Gates K, Kundu S, Ray PC. Multifunctional Nanoplatform for Highly Accurate Profiling of Triple-Negative Breast Cancer-Derived Chemo- and Immunotherapy Resistance Exosomes. ACS Appl Bio Mater. 2025 Jul 21; 8(7):5959-5969.

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Nakazawa S, Pecci F, Odintsov I, Gazgalis D, Gottlieb FH, Ricciuti B, Zullo L, Alessi JV, Di Federico A, Aldea M, Garbo E, Gandhi MM, Saini A, Feng WW, Jiang J, Baldacci S, Facchinetti F, Makarem M, Locquet MA, Haratani K, Haradon D, Besse B, Italiano A, Remon J, Lavaud P, Vasseur D, Planchard D, Sato Y, Watanabe Y, Owen S, Cortot AB, Mahran H, Forster MD, Niu J, Tomasini P, Leong SS, Tay K, Esteban E, Minchom A, Kizilbash SH, Cruz-Correa M, Yu KP, Zhang X, Chen P, Sangem M, Che J, Sholl LM, J?nne PA, Awad MM. Antitumor Activity of Vebreltinib and Characterization of Clinicogenomic Features in Solid Tumors with MET Rearrangements. Cancer Discov. 2025 Jun 03; 15(6):1129-1140.

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Sharma T, Mondal T, Saralamma VVG, Hassan MI, Kim CJ, Churqui MP, Nystr?m K, Thombare K, Baig MH, Dong JJ. Exploring the exportin-1 inhibitors for COVID-19 and anticancer treatment. J Biomol Struct Dyn. 2026 Jan; 44(1):463-474.

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