Otx Transcription Factors
"Otx Transcription Factors" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A family of VERTEBRATE homeodomain proteins that share homology with orthodenticle protein, Drosophila. They regulate GENETIC TRANSCRIPTION and play an important role in EMBRYONIC DEVELOPMENT of the BRAIN.
| Descriptor ID |
D051857
|
| MeSH Number(s) |
D12.776.260.400.718 D12.776.930.650
|
| Concept/Terms |
Otx Transcription Factors- Otx Transcription Factors
- Transcription Factors, Otx
- Otx Homeodomain Proteins
- Homeodomain Proteins, Otx
- Orthodenticle Homolog Homeodomain Proteins
|
Below are MeSH descriptors whose meaning is more general than "Otx Transcription Factors".
Below are MeSH descriptors whose meaning is more specific than "Otx Transcription Factors".
This graph shows the total number of publications written about "Otx Transcription Factors" by people in this website by year, and whether "Otx Transcription Factors" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2011 | 1 | 0 | 1 |
| 2013 | 1 | 0 | 1 |
| 2014 | 0 | 1 | 1 |
| 2020 | 2 | 0 | 2 |
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Below are the most recent publications written about "Otx Transcription Factors" by people in Profiles.
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Ghinia Tegla MG, Buenaventura DF, Kim DY, Thakurdin C, Gonzalez KC, Emerson MM. OTX2 represses sister cell fate choices in the developing retina to promote photoreceptor specification. Elife. 2020 04 29; 9.
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Patoori S, Jean-Charles N, Gopal A, Sulaiman S, Gopal S, Wang B, Souferi B, Emerson MM. Cis-regulatory analysis of Onecut1 expression in fate-restricted retinal progenitor cells. Neural Dev. 2020 03 19; 15(1):5.
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Wang S, Sengel C, Emerson MM, Cepko CL. A gene regulatory network controls the binary fate decision of rod and bipolar cells in the vertebrate retina. Dev Cell. 2014 Sep 08; 30(5):513-27.
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Emerson MM, Surzenko N, Goetz JJ, Trimarchi J, Cepko CL. Otx2 and Onecut1 promote the fates of cone photoreceptors and horizontal cells and repress rod photoreceptors. Dev Cell. 2013 Jul 15; 26(1):59-72.
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Emerson MM, Cepko CL. Identification of a retina-specific Otx2 enhancer element active in immature developing photoreceptors. Dev Biol. 2011 Dec 01; 360(1):241-55.