Peroxisome Proliferator-Activated Receptors

"Peroxisome Proliferator-Activated Receptors" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure, which enables searching at various levels of specificity.

MeSH information

Definition | Details | More General Concepts | Related Concepts | More Specific Concepts

TRANSCRIPTION FACTORS that are activated by ligands and heterodimerize with RETINOID X RECEPTORS and bind to peroxisome proliferator response elements in the promoter regions of target genes.

Descriptor ID	D047492
MeSH Number(s)	D12.776.826.239 D12.776.930.705
Concept/Terms	Peroxisome Proliferator-Activated Receptors Peroxisome Proliferator-Activated Receptors Peroxisome Proliferator Activated Receptors Proliferator-Activated Receptors, Peroxisome Receptors, Peroxisome Proliferator-Activated PPAR NUC1 PPAR NUC1 PPAR PPAR, NUC1

Below are MeSH descriptors whose meaning is more general than "Peroxisome Proliferator-Activated Receptors".

Chemicals and Drugs [D]
Amino Acids, Peptides, and Proteins [D12]
Proteins [D12.776]
Receptors, Cytoplasmic and Nuclear [D12.776.826]
Peroxisome Proliferator-Activated Receptors [D12.776.826.239]
Transcription Factors [D12.776.930]
Peroxisome Proliferator-Activated Receptors [D12.776.930.705]

Below are MeSH descriptors whose meaning is related to "Peroxisome Proliferator-Activated Receptors".

Below are MeSH descriptors whose meaning is more specific than "Peroxisome Proliferator-Activated Receptors".

Peroxisome Proliferator-Activated Receptors
PPAR alpha
PPAR delta
PPAR gamma
PPAR-beta

publications

Timeline | Most Recent

This graph shows the total number of publications written about "Peroxisome Proliferator-Activated Receptors" by people in this website by year, and whether "Peroxisome Proliferator-Activated Receptors" was a major or minor topic of these publications.

Bar chart showing 9 publications over 7 distinct years, with a maximum of 2 publications in 2011 and 2017

To see the data from this visualization as text, click here.

Year	Major Topic	Minor Topic	Total
2008	1	0	1
2009	0	1	1
2011	2	0	2
2014	1	0	1
2017	1	1	2
2018	1	0	1
2022	0	1	1

Below are the most recent publications written about "Peroxisome Proliferator-Activated Receptors" by people in Profiles.

Williams SD, Smith TM, Stewart LV, Sakwe AM. Hypoxia-Inducible Expression of Annexin A6 Enhances the Resistance of Triple-Negative Breast Cancer Cells to EGFR and AR Antagonists. Cells. 2022 09 27; 11(19).

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Khuchua Z, Glukhov AI, Strauss AW, Javadov S. Elucidating the Beneficial Role of PPAR Agonists in Cardiac Diseases. Int J Mol Sci. 2018 Nov 04; 19(11).

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Huang Y, Powers C, Moore V, Schafer C, Ren M, Phoon CK, James JF, Glukhov AV, Javadov S, Vaz FM, Jefferies JL, Strauss AW, Khuchua Z. The PPAR pan-agonist bezafibrate ameliorates cardiomyopathy in a mouse model of Barth syndrome. Orphanet J Rare Dis. 2017 03 09; 12(1):49.

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Irizarry KJL, Chan A, Kettle D, Kezian S, Ma D, Palacios L, Li QQ, Keeler CL, Drechsler Y. Bioinformatics Analysis of Chicken miRNAs Associated with Monocyte to Macrophage Differentiation and Subsequent IFN? Stimulated Activation. Microrna. 2017; 6(1):53-70.

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Zhao X, Zhang Y, Leander M, Li L, Wang G, Emmett N. Altered expression profile of renal a(1D)-adrenergic receptor in diabetes and its modulation by PPAR agonists. J Diabetes Res. 2014; 2014:725634.

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Oyekan A. PPARs and their effects on the cardiovascular system. Clin Exp Hypertens. 2011; 33(5):287-93.

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Thomas K, Sung DY, Chen X, Thompson W, Chen YE, McCarrey J, Walker W, Griswold M. Developmental patterns of PPAR and RXR gene expression during spermatogenesis. Front Biosci (Elite Ed). 2011 06 01; 3(4):1209-20.

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Guo Q, Wang G, Liu X, Namura S. Effects of gemfibrozil on outcome after permanent middle cerebral artery occlusion in mice. Brain Res. 2009 Jul 07; 1279:121-30.

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Magee TR, Han G, Cherian B, Khorram O, Ross MG, Desai M. Down-regulation of transcription factor peroxisome proliferator-activated receptor in programmed hepatic lipid dysregulation and inflammation in intrauterine growth-restricted offspring. Am J Obstet Gynecol. 2008 Sep; 199(3):271.e1-5.

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Villacorta L, Garcia-Barrio MT, Chen YE. Transcriptional regulation of peroxisome proliferator-activated receptors and liver X receptors. Curr Atheroscler Rep. 2007 Sep; 9(3):230-7.

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