PPAR gamma

"PPAR gamma" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure, which enables searching at various levels of specificity.

MeSH information

Definition | Details | More General Concepts | Related Concepts | More Specific Concepts

A nuclear transcription factor. Heterodimerization with RETINOID X RECEPTOR ALPHA is important in regulation of GLUCOSE metabolism and CELL GROWTH PROCESSES. It is a target of THIAZOLIDINEDIONES for control of DIABETES MELLITUS.

Descriptor ID	D047495
MeSH Number(s)	D12.776.826.239.588
Concept/Terms	PPAR gamma PPAR gamma PPARgamma Thiazolidinedione Receptor Receptor, Thiazolidinedione Peroxisome Proliferator-Activated Receptor gamma Peroxisome Proliferator Activated Receptor gamma PPARgamma3 PPARgamma3 PPARgamma2 PPARgamma2 mPPARgamma1 mPPARgamma1 mPPARgamma2 mPPARgamma2

Below are MeSH descriptors whose meaning is more general than "PPAR gamma".

Chemicals and Drugs [D]
Amino Acids, Peptides, and Proteins [D12]
Proteins [D12.776]
Receptors, Cytoplasmic and Nuclear [D12.776.826]
Peroxisome Proliferator-Activated Receptors [D12.776.826.239]
PPAR gamma [D12.776.826.239.588]

Below are MeSH descriptors whose meaning is related to "PPAR gamma".

Below are MeSH descriptors whose meaning is more specific than "PPAR gamma".

publications

Timeline | Most Recent

This graph shows the total number of publications written about "PPAR gamma" by people in this website by year, and whether "PPAR gamma" was a major or minor topic of these publications.

Bar chart showing 44 publications over 18 distinct years, with a maximum of 5 publications in 2007 and 2018

To see the data from this visualization as text, click here.

Year	Major Topic	Minor Topic	Total
2005	1	0	1
2006	1	0	1
2007	3	2	5
2008	1	2	3
2009	2	1	3
2010	2	1	3
2011	1	2	3
2012	1	2	3
2013	2	1	3
2014	2	2	4
2015	1	0	1
2016	1	0	1
2017	2	0	2
2018	1	4	5
2019	0	1	1
2021	1	0	1
2022	0	3	3
2024	0	1	1

Below are the most recent publications written about "PPAR gamma" by people in Profiles.

Ofosu-Boateng M, Shaik F, Choi S, Ekuban FA, Gebreyesus LH, Twum E, Nnamani DO, Yeyeodu ST, Yadak N, Collier DM, Gyamfi MA. High-fat diet induced obesity promotes inflammation, oxidative stress, and hepatotoxicity in female FVB/N mice. Biofactors. 2024 May-Jun; 50(3):572-591.

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Yousefzadeh N, Jeddi S, Afzali H, Kashfi K, Ghasemi A. Chronic nitrate administration increases the expression the genes involved in the browning of white adipose tissue in female rats. Cell Biochem Funct. 2022 Oct; 40(7):750-759.

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Roy S, Bhowmik DR, Begum R, Amin MT, Islam MA, Ahmed F, Hossain MS. Aspirin attenuates the expression of adhesion molecules, risk of obesity, and adipose tissue inflammation in high-fat diet-induced obese mice. Prostaglandins Other Lipid Mediat. 2022 10; 162:106664.

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Xu N, Li X, Weng J, Wei C, He Z, Doycheva DM, Lenahan C, Tang W, Zhou J, Liu Y, Xu Q, Liu Y, He X, Tang J, Zhang JH, Duan C. Adiponectin Ameliorates GMH-Induced Brain Injury by Regulating Microglia M1/M2 Polarization Via AdipoR1/APPL1/AMPK/PPAR? Signaling Pathway in Neonatal Rats. Front Immunol. 2022; 13:873382.

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Tilekar K, Hess JD, Upadhyay N, Bianco AL, Schweipert M, Laghezza A, Loiodice F, Meyer-Almes FJ, Aguilera RJ, Lavecchia A, C S R. Thiazolidinedione "Magic Bullets" Simultaneously Targeting PPAR? and HDACs: Design, Synthesis, and Investigations of their In Vitro and In Vivo Antitumor Effects. J Med Chem. 2021 05 27; 64(10):6949-6971.

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Arnold JM, Gu F, Ambati CR, Rasaily U, Ramirez-Pena E, Joseph R, Manikkam M, San Martin R, Charles C, Pan Y, Chatterjee SS, Den Hollander P, Zhang W, Nagi C, Sikora AG, Rowley D, Putluri N, Zhang XH, Karanam B, Mani SA, Sreekumar A. UDP-glucose 6-dehydrogenase regulates hyaluronic acid production and promotes breast cancer progression. Oncogene. 2020 04; 39(15):3089-3101.

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Krishnan V, Baskaran P, Thyagarajan B. Troglitazone activates TRPV1 and causes deacetylation of PPAR? in 3T3-L1 cells. Biochim Biophys Acta Mol Basis Dis. 2019 02 01; 1865(2):445-453.

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Chang L, Zhao X, Garcia-Barrio M, Zhang J, Eugene Chen Y. MitoNEET in Perivascular Adipose Tissue Prevents Arterial Stiffness in Aging Mice. Cardiovasc Drugs Ther. 2018 10; 32(5):531-539.

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Oyagbemi AA, Omobowale TO, Ola-Davies OE, Asenuga ER, Ajibade TO, Adejumobi OA, Arojojoye OA, Afolabi JM, Ogunpolu BS, Falayi OO, Hassan FO, Ochigbo GO, Saba AB, Adedapo AA, Yakubu MA. Quercetin attenuates hypertension induced by sodium fluoride via reduction in oxidative stress and modulation of HSP 70/ERK/PPAR? signaling pathways. Biofactors. 2018 Sep; 44(5):465-479.

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Xiong W, Zhao X, Villacorta L, Rom O, Garcia-Barrio MT, Guo Y, Fan Y, Zhu T, Zhang J, Zeng R, Chen YE, Jiang Z, Chang L. Brown Adipocyte-Specific PPAR? (Peroxisome Proliferator-Activated Receptor ?) Deletion Impairs Perivascular Adipose Tissue Development and Enhances Atherosclerosis in Mice. Arterioscler Thromb Vasc Biol. 2018 08; 38(8):1738-1747.

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