"Steroidogenic Factor 1" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A transcription factor and member of the nuclear receptor family NR5 that is expressed throughout the adrenal and reproductive axes during development. It plays an important role in sexual differentiation, formation of primary steroidogenic tissues, and their functions in post-natal and adult life. It regulates the expression of key steroidogenic enzymes.
| Descriptor ID |
D054339
|
| MeSH Number(s) |
D12.776.826.925
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| Concept/Terms |
Steroidogenic Factor 1- Steroidogenic Factor 1
- Ad4-Binding Protein
- Ad4 Binding Protein
- Adrenal 4 Binding Protein
- AD4BP Protein
- Fushi Tarazu Factor Homolog 1
- NR5A1 Protein
- Nuclear Receptor 5A1 Protein
- FTZF1 Protein
- SF-1 Transcription Factor
- Transcription Factor, SF-1
- Steroid Hormone Receptor Ad4BP
|
Below are MeSH descriptors whose meaning is more general than "Steroidogenic Factor 1".
Below are MeSH descriptors whose meaning is more specific than "Steroidogenic Factor 1".
This graph shows the total number of publications written about "Steroidogenic Factor 1" by people in this website by year, and whether "Steroidogenic Factor 1" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2002 | 0 | 1 | 1 |
| 2003 | 0 | 1 | 1 |
| 2010 | 2 | 1 | 3 |
| 2013 | 0 | 1 | 1 |
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Below are the most recent publications written about "Steroidogenic Factor 1" by people in Profiles.
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Wood MA, Acharya A, Finco I, Swonger JM, Elston MJ, Tallquist MD, Hammer GD. Fetal adrenal capsular cells serve as progenitor cells for steroidogenic and stromal adrenocortical cell lineages in M. musculus. Development. 2013 Nov; 140(22):4522-32.
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Yazawa T, Kawabe S, Inaoka Y, Okada R, Mizutani T, Imamichi Y, Ju Y, Yamazaki Y, Usami Y, Kuribayashi M, Umezawa A, Miyamoto K. Differentiation of mesenchymal stem cells and embryonic stem cells into steroidogenic cells using steroidogenic factor-1 and liver receptor homolog-1. Mol Cell Endocrinol. 2011 Apr 10; 336(1-2):127-32.
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Chen MC, Wang SW, Kan SF, Tsai SC, Wu YC, Wang PS. Stimulatory effects of propylthiouracil on pregnenolone production through upregulation of steroidogenic acute regulatory protein expression in rat granulosa cells. Toxicol Sci. 2010 Dec; 118(2):667-74.
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Yazawa T, Inaoka Y, Okada R, Mizutani T, Yamazaki Y, Usami Y, Kuribayashi M, Orisaka M, Umezawa A, Miyamoto K. PPAR-gamma coactivator-1alpha regulates progesterone production in ovarian granulosa cells with SF-1 and LRH-1. Mol Endocrinol. 2010 Mar; 24(3):485-96.
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Mayer LP, Dyer CA, Propper CR. Exposure to 4-tert-octylphenol accelerates sexual differentiation and disrupts expression of steroidogenic factor 1 in developing bullfrogs. Environ Health Perspect. 2003 Apr; 111(4):557-61.
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Mayer LP, Overstreet SL, Dyer CA, Propper CR. Sexually dimorphic expression of steroidogenic factor 1 (SF-1) in developing gonads of the American bullfrog, Rana catesbeiana. Gen Comp Endocrinol. 2002 Jun 01; 127(1):40-7.