Ghrelin

"Ghrelin" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure, which enables searching at various levels of specificity.

MeSH information

Definition | Details | More General Concepts | Related Concepts | More Specific Concepts

A 28-amino acid, acylated, orexigenic peptide that is a ligand for GROWTH HORMONE SECRETAGOGUE RECEPTORS. Ghrelin is widely expressed but primarily in the stomach in the adults. Ghrelin acts centrally to stimulate growth hormone secretion and food intake, and peripherally to regulate energy homeostasis. Its large precursor protein, known as appetite-regulating hormone or motilin-related peptide, contains ghrelin and obestatin.

Descriptor ID	D054439
MeSH Number(s)	D06.472.699.301 D12.644.548.322
Concept/Terms	Ghrelin Ghrelin GHRL Protein GHRL Protein Ppghrelin Ghrelin-Obestatin Preprohormone Ghrelin Obestatin Preprohormone Motilin-Related Peptide Precursor Motilin Related Peptide Precursor Peptide Precursor, Motilin-Related Precursor, Motilin-Related Peptide PpMTLRP Ghrelin Precursor Precursor, Ghrelin Obestatin Obestatin Appetite-Regulating Hormone Appetite-Regulating Hormone Appetite Regulating Hormone Motilin-Related Peptide Motilin Related Peptide Gastric MLTRP

Below are MeSH descriptors whose meaning is more general than "Ghrelin".

Chemicals and Drugs [D]
Hormones, Hormone Substitutes, and Hormone Antagonists [D06]
Hormones [D06.472]
Peptide Hormones [D06.472.699]
Ghrelin [D06.472.699.301]
Amino Acids, Peptides, and Proteins [D12]
Peptides [D12.644]
Peptide Hormones [D12.644.548]
Ghrelin [D12.644.548.322]

Below are MeSH descriptors whose meaning is more specific than "Ghrelin".

publications

Timeline | Most Recent

This graph shows the total number of publications written about "Ghrelin" by people in this website by year, and whether "Ghrelin" was a major or minor topic of these publications.

Bar chart showing 12 publications over 9 distinct years, with a maximum of 2 publications in 2006 and 2011 and 2020

To see the data from this visualization as text, click here.

Year	Major Topic	Minor Topic	Total
2004	0	1	1
2006	0	2	2
2008	1	0	1
2011	2	0	2
2013	1	0	1
2016	1	0	1
2017	1	0	1
2019	1	0	1
2020	1	1	2

Below are the most recent publications written about "Ghrelin" by people in Profiles.

Tchio C, Baba K, Piccione G, Tosini G. Removal of melatonin receptor type 1 signalling induces dyslipidaemia and hormonal changes in mice subjected to environmental circadian disruption. Endocrinol Diabetes Metab. 2021 01; 4(1):e00171.

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O'Neill MJ, Chan K, Jaynes JM, Knotts Z, Xu X, Abisoye-Ogunniyan A, Guerin T, Schlomer J, Li D, Cary JW, Rajasekaran K, Yates C, Kozlov S, Andresson T, Rudloff U. LC-MS/MS assay coupled with carboxylic acid magnetic bead affinity capture to quantitatively measure cationic host defense peptides (HDPs) in complex matrices with application to preclinical pharmacokinetic studies. J Pharm Biomed Anal. 2020 Mar 20; 181:113093.

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Pritchett NR, Maziarz M, Shu XO, Kamangar F, Dawsey SM, Fan JH, Ji BT, Gao YT, Xiang YB, Qiao YL, Li H, Yang G, Wang SM, Stanczyk FZ, Chow WH, Katki HA, Zheng W, Lan Q, Freedman ND, Rothman N, Abnet CC, Murphy G. Serum ghrelin and esophageal and gastric cancer in two cohorts in China. Int J Cancer. 2020 05 15; 146(10):2728-2735.

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Murphy G, Cross AJ, Dawsey SM, Stanczyk FZ, Kamangar F, Weinstein SJ, Taylor PR, M?nnist? S, Albanes D, Abnet CC, Freedman ND. Serum ghrelin is associated with risk of colorectal adenocarcinomas in the ATBC study. Gut. 2018 09; 67(9):1646-1651.

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Balivada S, Pawar HN, Montgomery S, Kenney MJ. Effect of ghrelin on regulation of splenic sympathetic nerve discharge. Auton Neurosci. 2016 12; 201:68-71.

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Fluitt MB, Gambhir KK, Nunlee-Bland G, Odonkor W. Fasting plasma ghrelin levels are reduced, but not suppressed during OGTT in obese African American adolescents. Ethn Dis. 2013; 23(4):436-40.

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Murphy G, Kamangar F, Albanes D, Stanczyk FZ, Weinstein SJ, Taylor PR, Virtamo J, Abnet CC, Dawsey SM, Freedman ND. Serum ghrelin is inversely associated with risk of subsequent oesophageal squamous cell carcinoma. Gut. 2012 Nov; 61(11):1533-7.

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Murphy G, Kamangar F, Dawsey SM, Stanczyk FZ, Weinstein SJ, Taylor PR, Virtamo J, Abnet CC, Albanes D, Freedman ND. The relationship between serum ghrelin and the risk of gastric and esophagogastric junctional adenocarcinomas. J Natl Cancer Inst. 2011 Jul 20; 103(14):1123-9.

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Stewart ML, Nikhanj SD, Timm DA, Thomas W, Slavin JL. Evaluation of the effect of four fibers on laxation, gastrointestinal tolerance and serum markers in healthy humans. Ann Nutr Metab. 2010; 56(2):91-8.

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Nguyen T, Desai M, Ross MG. Programmed alterations in hypothalamic neuronal orexigenic responses to ghrelin following gestational nutrient restriction. Reprod Sci. 2008 Sep; 15(7):702-9.

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