Retinal Pigment Epithelium
"Retinal Pigment Epithelium" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
The single layer of pigment-containing epithelial cells in the RETINA, situated closely to the tips (outer segments) of the RETINAL PHOTORECEPTOR CELLS. These epithelial cells are macroglia that perform essential functions for the photoreceptor cells, such as in nutrient transport, phagocytosis of the shed photoreceptor membranes, and ensuring retinal attachment.
Descriptor ID |
D055213
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MeSH Number(s) |
A09.371.670.500 A09.371.729.887
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Concept/Terms |
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Below are MeSH descriptors whose meaning is more general than "Retinal Pigment Epithelium".
Below are MeSH descriptors whose meaning is more specific than "Retinal Pigment Epithelium".
This graph shows the total number of publications written about "Retinal Pigment Epithelium" by people in this website by year, and whether "Retinal Pigment Epithelium" was a major or minor topic of these publications.
To see the data from this visualization as text,
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Year | Major Topic | Minor Topic | Total |
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2008 | 1 | 0 | 1 |
2009 | 1 | 0 | 1 |
2010 | 1 | 0 | 1 |
2011 | 2 | 1 | 3 |
2012 | 2 | 1 | 3 |
2013 | 1 | 0 | 1 |
2014 | 1 | 0 | 1 |
2017 | 2 | 2 | 4 |
2018 | 0 | 2 | 2 |
2020 | 4 | 1 | 5 |
2021 | 1 | 0 | 1 |
2022 | 1 | 3 | 4 |
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Below are the most recent publications written about "Retinal Pigment Epithelium" by people in Profiles.
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Sun M, Cherian N, Liu L, Chan AM, Aguirre B, Chu A, Strawbridge J, Kim ES, Lin MC, Tsui I, Gordon LK, Wadehra M. Epithelial membrane protein 2 (EMP2) regulates hypoxia-induced angiogenesis in the adult retinal pigment epithelial cell lines. Sci Rep. 2022 11 12; 12(1):19432.
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DeVera C, Dixon J, Chrenek MA, Baba K, Le YZ, Iuvone PM, Tosini G. The Circadian Clock in the Retinal Pigment Epithelium Controls the Diurnal Rhythm of Phagocytic Activity. Int J Mol Sci. 2022 May 10; 23(10).
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Baba K, Goyal V, Tosini G. Circadian Regulation of Retinal Pigment Epithelium Function. Int J Mol Sci. 2022 Feb 28; 23(5).
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Baba K, Tosini G. Real-Time Monitoring of Circadian Rhythms in the Eye. Methods Mol Biol. 2022; 2550:367-375.
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Rohrer B, Biswal MR, Obert E, Dang Y, Su Y, Zuo X, Fogelgren B, Kondkar AA, Lobo GP, Lipschutz JH. Conditional Loss of the Exocyst Component Exoc5 in Retinal Pigment Epithelium (RPE) Results in RPE Dysfunction, Photoreceptor Cell Degeneration, and Decreased Visual Function. Int J Mol Sci. 2021 May 11; 22(10).
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Goyal V, DeVera C, Baba K, Sellers J, Chrenek MA, Iuvone PM, Tosini G. Photoreceptor Degeneration in Homozygous Male Per2luc Mice During Aging. J Biol Rhythms. 2021 04; 36(2):137-145.
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Goyal V, DeVera C, Laurent V, Sellers J, Chrenek MA, Hicks D, Baba K, Iuvone PM, Tosini G. Dopamine 2 Receptor Signaling Controls the Daily Burst in Phagocytic Activity in the Mouse Retinal Pigment Epithelium. Invest Ophthalmol Vis Sci. 2020 05 11; 61(5):10.
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DeVera C, Tosini G. Circadian analysis of the mouse retinal pigment epithelium transcriptome. Exp Eye Res. 2020 04; 193:107988.
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Sun M, Wadehra M, Casero D, Lin MC, Aguirre B, Parikh S, Matynia A, Gordon L, Chu A. Epithelial Membrane Protein 2 (EMP2) Promotes VEGF-Induced Pathological Neovascularization in Murine Oxygen-Induced Retinopathy. Invest Ophthalmol Vis Sci. 2020 02 07; 61(2):3.
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Ma L, Ng M, van der Weele CM, Yoshizawa M, Jeffery WR. Dual roles of the retinal pigment epithelium and lens in cavefish eye degeneration. J Exp Zool B Mol Dev Evol. 2020 11; 334(7-8):438-449.