"Melatonin" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A biogenic amine that is found in animals and plants. In mammals, melatonin is produced by the PINEAL GLAND. Its secretion increases in darkness and decreases during exposure to light. Melatonin is implicated in the regulation of SLEEP, mood, and REPRODUCTION. Melatonin is also an effective antioxidant.
Descriptor ID |
D008550
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MeSH Number(s) |
D03.633.100.473.914.481 D06.472.506
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Concept/Terms |
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Below are MeSH descriptors whose meaning is more general than "Melatonin".
Below are MeSH descriptors whose meaning is more specific than "Melatonin".
This graph shows the total number of publications written about "Melatonin" by people in this website by year, and whether "Melatonin" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
Year | Major Topic | Minor Topic | Total |
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1994 | 0 | 1 | 1 |
1996 | 2 | 0 | 2 |
1997 | 0 | 2 | 2 |
1998 | 1 | 2 | 3 |
2000 | 2 | 1 | 3 |
2001 | 3 | 1 | 4 |
2002 | 3 | 1 | 4 |
2003 | 4 | 1 | 5 |
2004 | 3 | 3 | 6 |
2005 | 2 | 1 | 3 |
2006 | 2 | 2 | 4 |
2007 | 1 | 2 | 3 |
2008 | 4 | 2 | 6 |
2009 | 1 | 0 | 1 |
2010 | 3 | 0 | 3 |
2011 | 2 | 0 | 2 |
2012 | 3 | 0 | 3 |
2013 | 0 | 1 | 1 |
2014 | 1 | 1 | 2 |
2015 | 4 | 0 | 4 |
2016 | 1 | 0 | 1 |
2017 | 2 | 2 | 4 |
2018 | 1 | 1 | 2 |
2019 | 1 | 1 | 2 |
2020 | 1 | 0 | 1 |
2022 | 1 | 0 | 1 |
2023 | 1 | 0 | 1 |
2024 | 1 | 0 | 1 |
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Below are the most recent publications written about "Melatonin" by people in Profiles.
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Felder-Schmittbuhl MP, Hicks D, Ribelayga CP, Tosini G. Melatonin in the mammalian retina: Synthesis, mechanisms of action and neuroprotection. J Pineal Res. 2024 04; 76(3):e12951.
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Wilson JB, Epstein M, Lopez B, Brown AK, Lutfy K, Friedman TC. The role of Neurochemicals, Stress Hormones and Immune System in the Positive Feedback Loops between Diabetes, Obesity and Depression. Front Endocrinol (Lausanne). 2023; 14:1224612.
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Baba K, Tosini G. Assessing the Role of Melatonin in the Modulation of Visual Functions in the Mouse. Methods Mol Biol. 2022; 2550:377-389.
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Buonfiglio D, Hummer DL, Armstrong A, Christopher Ehlen J, DeBruyne JP. Angelman syndrome and melatonin: What can they teach us about sleep regulation. J Pineal Res. 2020 Nov; 69(4):e12697.
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S?nchez-Breta?o A, Suen TC, Baba K, DeBruyne J, Tosini G. Melatonin receptor heterodimerization in a photoreceptor-like cell line endogenously expressing melatonin receptors. Mol Vis. 2019; 25:791-799.
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Jilg A, Bechstein P, Saade A, Dick M, Li TX, Tosini G, Rami A, Zemmar A, Stehle JH. Melatonin modulates daytime-dependent synaptic plasticity and learning efficiency. J Pineal Res. 2019 Apr; 66(3):e12553.
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Felder-Schmittbuhl MP, Buhr ED, Dkhissi-Benyahya O, Hicks D, Peirson SN, Ribelayga CP, Sandu C, Spessert R, Tosini G. Ocular Clocks: Adapting Mechanisms for Eye Functions and Health. Invest Ophthalmol Vis Sci. 2018 10 01; 59(12):4856-4870.
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Piano I, Baba K, Tosini G. Heteromeric MT1/MT2 melatonin receptors modulate the scotopic electroretinogram via PKC? in mice. Exp Eye Res. 2018 12; 177:50-54.
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S?nchez-Breta?o A, Baba K, Janjua U, Piano I, Gargini C, Tosini G. Melatonin partially protects 661W cells from H2O2-induced death by inhibiting Fas/FasL-caspase-3. Mol Vis. 2017; 23:844-852.
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Yoshimoto FK, Arman HD, Griffith WP, Yan F, Wherritt DJ. Chemical synthesis of 7a-hydroxypregnenolone, a neuroactive steroid that stimulates locomotor activity. Steroids. 2017 12; 128:50-57.