Enzyme-Linked Immunosorbent Assay

"Enzyme-Linked Immunosorbent Assay" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure, which enables searching at various levels of specificity.

MeSH information

Definition | Details | More General Concepts | Related Concepts | More Specific Concepts

An immunoassay utilizing an antibody labeled with an enzyme marker such as horseradish peroxidase. While either the enzyme or the antibody is bound to an immunosorbent substrate, they both retain their biologic activity; the change in enzyme activity as a result of the enzyme-antibody-antigen reaction is proportional to the concentration of the antigen and can be measured spectrophotometrically or with the naked eye. Many variations of the method have been developed.

Descriptor ID	D004797
MeSH Number(s)	E05.478.566.350.170 E05.478.566.380.360 E05.478.583.400.170 E05.601.470.350.170 E05.601.470.380.360
Concept/Terms	Enzyme-Linked Immunosorbent Assay Enzyme-Linked Immunosorbent Assay Assay, Enzyme-Linked Immunosorbent Assays, Enzyme-Linked Immunosorbent Enzyme Linked Immunosorbent Assay Enzyme-Linked Immunosorbent Assays Immunosorbent Assay, Enzyme-Linked Immunosorbent Assays, Enzyme-Linked ELISA

Below are MeSH descriptors whose meaning is more general than "Enzyme-Linked Immunosorbent Assay".

Analytical, Diagnostic and Therapeutic Techniques and Equipment [E]
Investigative Techniques [E05]
Immunologic Techniques [E05.478]
Immunoassay [E05.478.566]
Immunoenzyme Techniques [E05.478.566.350]
Enzyme-Linked Immunosorbent Assay [E05.478.566.350.170]
Immunosorbent Techniques [E05.478.566.380]
Enzyme-Linked Immunosorbent Assay [E05.478.566.380.360]
Immunohistochemistry [E05.478.583]
Immunoenzyme Techniques [E05.478.583.400]
Enzyme-Linked Immunosorbent Assay [E05.478.583.400.170]
Molecular Probe Techniques [E05.601]
Immunoassay [E05.601.470]
Immunoenzyme Techniques [E05.601.470.350]
Enzyme-Linked Immunosorbent Assay [E05.601.470.350.170]
Immunosorbent Techniques [E05.601.470.380]
Enzyme-Linked Immunosorbent Assay [E05.601.470.380.360]

Below are MeSH descriptors whose meaning is related to "Enzyme-Linked Immunosorbent Assay".

Below are MeSH descriptors whose meaning is more specific than "Enzyme-Linked Immunosorbent Assay".

Enzyme-Linked Immunosorbent Assay
Enzyme-Linked Immunospot Assay

publications

Timeline | Most Recent

This graph shows the total number of publications written about "Enzyme-Linked Immunosorbent Assay" by people in this website by year, and whether "Enzyme-Linked Immunosorbent Assay" was a major or minor topic of these publications.

Bar chart showing 332 publications over 29 distinct years, with a maximum of 24 publications in 2012

To see the data from this visualization as text, click here.

Year	Major Topic	Minor Topic	Total
1994	0	1	1
1995	0	4	4
1996	0	2	2
1997	0	3	3
1998	1	1	2
1999	0	6	6
2000	0	11	11
2001	0	4	4
2002	0	9	9
2003	1	11	12
2004	0	17	17
2005	3	19	22
2006	5	12	17
2007	4	13	17
2008	4	18	22
2009	2	18	20
2010	3	18	21
2011	1	21	22
2012	3	21	24
2013	2	15	17
2014	1	9	10
2015	0	14	14
2016	0	18	18
2017	0	10	10
2018	0	12	12
2019	1	3	4
2020	1	4	5
2021	2	2	4
2022	0	2	2

Below are the most recent publications written about "Enzyme-Linked Immunosorbent Assay" by people in Profiles.

Schuettenberg A, Pi?a A, Metrailer M, Pel?ez-S?nchez RG, Agudelo-Fl?rez P, Lopez J?, Ryle L, Monroy FP, Altin JA, Ladner JT. Highly Multiplexed Serology for Nonhuman Mammals. Microbiol Spectr. 2022 10 26; 10(5):e0287322.

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Munoz-Jordan J, Cardona J, Beltr?n M, Col?n C, Schiffer J, Stewart-Clark E, Zellner B, Semenova V, Li Y, Jia LT, Maniatis P, Pawloski L, Adams L, Paz-Bailey G, Rivera-Amill V, Medina F. Evaluation of Serologic Cross-Reactivity Between Dengue Virus and SARS-CoV-2 in Patients with Acute Febrile Illness - United States and Puerto Rico, April 2020-March 2021. MMWR Morb Mortal Wkly Rep. 2022 Mar 11; 71(10):375-377.

View in: PubMed
Gojanovich GS, Jacobson DL, Broadwell C, Karalius B, Kirmse B, Geffner ME, Jao J, Van Dyke RB, McFarland EJ, Silio M, Crain M, Gerschenson M. Associations of FGF21 and GDF15 with mitochondrial dysfunction in children living with perinatally-acquired HIV: A cross-sectional evaluation of pediatric AIDS clinical trials group 219/219C. PLoS One. 2021; 16(12):e0261563.

View in: PubMed
Medina FA, Vila F, Premkumar L, Lorenzi O, Paz-Bailey G, Alvarado LI, Rivera-Amill V, de Silva A, Waterman S, Mu?oz-Jord?n J. Capacity of a Multiplex IgM Antibody Capture ELISA to Differentiate Zika and Dengue Virus Infections in Areas of Concurrent Endemic Transmission. Am J Trop Med Hyg. 2021 12 20; 106(2):585-592.

View in: PubMed
Hsieh SC, Tsai WY, Tsai JJ, Stone M, Simmons G, Busch MP, Lanteri M, Stramer SL, Balmaseda A, Harris E, Wang WK. Identification of Anti-Premembrane Antibody as a Serocomplex-Specific Marker To Discriminate Zika, Dengue, and West Nile Virus Infections. J Virol. 2021 09 09; 95(19):e0061921.

View in: PubMed
Ma L, Abugalyon Y, Li X. Multicolorimetric ELISA biosensors on a paper/polymer hybrid analytical device for visual point-of-care detection of infection diseases. Anal Bioanal Chem. 2021 Jul; 413(18):4655-4663.

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Tsai WY, Driesse K, Tsai JJ, Hsieh SC, Sznajder Granat R, Jenkins O, Chang GJ, Wang WK. Enzyme-linked immunosorbent assays using virus-like particles containing mutations of conserved residues on envelope protein can distinguish three flavivirus infections. Emerg Microbes Infect. 2020 Dec; 9(1):1722-1732.

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Watts DM, Rodriguez CM, Palermo PM, Suarez V, Wong SJ, Orbegozo J, Dupuis AP, Kramer LD, Gonzalez FJ, Handel GA. Serosurvey for dengue virus infection among pregnant women in the West Nile virus enzootic community of El Paso Texas. PLoS One. 2020; 15(11):e0242889.

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Taylor DW, Bobbili N, Kayatani A, Tassi Yunga S, Kidima W, Leke RFG. Measuring antibody avidity to Plasmodium falciparum merozoite antigens using a multiplex immunoassay approach. Malar J. 2020 May 01; 19(1):171.

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Casta?eda-Avila MA, Su?rez-P?rez E, Bernabe-Dones R, Unger ER, Panicker G, Ortiz AP. Chlamydia Trachomatis and Human Papillomavirus Serostatus in Puerto Rican Women. P R Health Sci J. 2020 03; 39(1):28-33.

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