"Cortactin" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A microfilament protein that interacts with F-ACTIN and regulates cortical actin assembly and organization. It is also an SH3 DOMAIN containing phosphoprotein, and it mediates tyrosine PHOSPHORYLATION based SIGNAL TRANSDUCTION by PROTO-ONCOGENE PROTEIN PP60(C-SRC).
| Descriptor ID |
D051356
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| MeSH Number(s) |
D05.750.078.730.281 D12.644.360.024.280 D12.776.157.057.014 D12.776.220.525.281 D12.776.476.024.311 D12.776.744.390
|
| Concept/Terms |
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Below are MeSH descriptors whose meaning is more general than "Cortactin".
Below are MeSH descriptors whose meaning is more specific than "Cortactin".
This graph shows the total number of publications written about "Cortactin" by people in this website by year, and whether "Cortactin" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2004 | 0 | 1 | 1 |
| 2016 | 1 | 0 | 1 |
| 2017 | 1 | 0 | 1 |
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Below are the most recent publications written about "Cortactin" by people in Profiles.
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Alicea D, Perez M, Maldonado C, Dominicci-Cotto C, Marie B. Cortactin Is a Regulator of Activity-Dependent Synaptic Plasticity Controlled by Wingless. J Neurosci. 2017 02 22; 37(8):2203-2215.
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Adams G, Zhou J, Wang W, Wu H, Quan J, Liu Y, Xia P, Wang Z, Zhou S, Jiang J, Mo F, Zhuang X, Thomas K, Hill DL, Aikhionbare FO, He P, Liu X, Ding X, Yao X. The Microtubule Plus End Tracking Protein TIP150 Interacts with Cortactin to Steer Directional Cell Migration. J Biol Chem. 2016 09 23; 291(39):20692-706.
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Qian A, Meals RA, Rajfer J, Gonzalez-Cadavid NF. Comparison of gene expression profiles between Peyronie's disease and Dupuytren's contracture. Urology. 2004 Aug; 64(2):399-404.